• Advances in Traditional Medicine
• /
• v.8 no.4
• /
• pp.365-373
• /
• 2008

Murraya koenigii leaves commonly known as 'curry patta' are routinely added to Indian gravy and vegetarian dishes by south Indian as a favourate condiment. The present study was undertaken to investigate the effects of Murraya koenigii leaves (MKL) on memory in rats. Elevated plus-maze and Hebb-Williams maze served as the exteroceptive behavioral models for testing memory. Diazepam-, scopolamine- and ageing-induced amnesia served as the interoceptive behavioral models. MKL fed orally to various groups of young and aged rats with diet containing 2, 4 and 8% w/w of MKL for 30 days consecutively were investigated. The MKL diets produced a significant dose-dependent improvement in memory scores of young and aged rats and significantly reduced the amnesia induced by scopolamine (0.4 mg/kg, i.p.) and diazepam (1 mg/kg, i.p.). Therefore, it would be worthwhile to specifically investigate the therapeutic potential of MKL in the management of dementia patients.

• Advances in nano research
• /
• v.11 no.6
• /
• pp.657-665
• /
• 2021

The present work aimed to explore green approach via aqueous leaves extract of Murraya koenigii (ALEMk) for the synthesis of silver nanoparticles (AgNPsMk) in single step. The synthesis process was visualized with a color change and monitored by employing UV/Visible spectroscopy and a clear peak attained at 420 nm confirming the synthesis of AgNPsMk. The possible functional groups present in the extract which participated in the synthesis of AgNPsMk were identified with the help of FTIR spectroscopy. Further characterization using TEM images revealed the spherical shape of AgNPsMk with average particle size of 20 nm displaying well dispersion throughout the solution. Pronounced antioxidant activities of AgNPsMk at increased concentrations observed which evidencing strong radical scavenging ability. Moreover, AgNPsMk exhibited strong antibacterial behavior when tested against bacterial strains of Escherichia coli and Bacillus subtilis. Moving ahead, in vitro cytotoxicity work revealed potent cell viability loss appearing in AU565 and HeLa cancer cell lines on exposure to AgNPsMk at increased concentration. Finally, in vivo assessment carried out inside male Wistar rats indicated non toxic effect on examined liver tissues besides biochemical analysis including bilirubin, alkaline phosphtase (ALP) and serum glutamate pyruvate transaminase (SGPT) which found within the normal range when compared with control. The prior research work profoundly apprises the potential of green synthesized AgNPsMk to play a significant role in biomedical applications and formulations.

• Korean Journal of Poultry Science
• /
• v.43 no.3
• /
• pp.169-176
• /
• 2016

An experiment was conducted to evaluate the growth performance and meat quality traits of broilers fed a diet supplemented with dry-ground curry leaves (Murraya koenigii). A total of 750 one-day-old broiler chicks (Cobbs 500) were arranged in the experiment with a completely randomized design and allotted to one of five treatments, with $T_1-Control$ and $T_2-T_5$ curry leaves powder levels (i.e., 0.3%, 0.6%, 0.9% and 1.2%, respectively). The initial body weights, final body weights and daily feed intake were measured over an experimental period of 32 days. At the conclusion of the experiment, the carcass weights and meat quality parameters were measured. The birds fed diets supplemented with curry leaves powder had a higher weight gain (P<0.05; ADG), improved feed conversion ratio (P<0.05; FCR) and lower mortality (P<0.05) rates compared to the birds in the control group. Nonetheless, there was no difference (P>0.05) in feed intake among the dietary treatments. Similarly, supplementation of curry leaves powder had no effect (P>0.05) on the proportions of the carcass, leg meat and drumstick. No differences were (P>0.05) observed in cooking loss or the pH of meat from broilers fed the curry leaves supplemented diet. However, curry leaf supplementation affected (P<0.05) the meat water holding capacity. A sensory evaluation showed higher levels of taste and tenderness in meat from broilers fed with curry leaves powder. In conclusion, our results suggested that curry leaves powder improved the growth performance of broilers, with a lower incidence of mortality and improvement of some meat qualities.

• International Journal of Industrial Entomology and Biomaterials
• /
• v.47 no.1
• /
• pp.12-24
• /
• 2023

Sitophilus oryzae L. (Rice Weevil) is a stored pest of rice that causes extensive loss throughout the world. We tested the leaf powders of 12 plant species viz., Chrysanthemum sp., Cinnamomum zeylanicum, Citrus grandis, Citrus limon, Gliricidia sepium, Gymnema sylvestre, Hemigraphis colorata, Michelia champaca, Moringa oleifera, Murraya koenigii, Polyalthia longifolia, and Sauropus androgynus at dosages of 1.00, 1.50, 2.00 and 3.00g against the adult rice weevil and mortality was recorded at 1, 2, 3, 5, 7, 12 and 2l days after treatment (DAT) by direct contact toxicity for their adulticidal effect. We observed 100 percent adult mortality in C. zevlanicum and M. koenigii among the tested leaf powders. In addition, the first-time tested H. colorata and S. androgynus also caused high mortality compared to other plants. All the plant powders caused moderate to high adult mortality. Hence, these plants could be effective botanical insecticides against S. oryzae as they comprise a potential source of bioactive chemicals and are generally free from toxicants. Applications of these natural derivatives in S. oryzae control could reduce the cost of control methods and storage of rice contamination. Therefore, the present study indicates that some plant extracts can be used as an alternative to toxic synthetic chemicals in the management of rice weevils.