• The Transactions of the Korean Institute of Power Electronics
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• v.9 no.1
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• pp.36-41
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• 2004

In this paper a large scale STATCOM using double-connected multi-step inverter is proposed and operating principle along with control method is detailed. A simple auxiliary circuit including an interphase transformer is employed to improve output voltage waveform of 12-step into 36-step. The proposed scheme could be a cost effective approach in high power applications such as 10MVar to 30MVar STATCOM. Experimental results from a 2KVA laboratory prototype show validity of the proposed method.

• Proceedings of the Korean Society for Technology of Plasticity Conference
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• 2002.02a
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• pp.239-244
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• 2002

In this study, we developed the manufacturing technology of micro-hole and micro-shaft for micro punching system using micro electrical discharge machining and micro electro chemical machining. Micro punching dies of tungsten carbide with $55\;{\mu}m\;and\;110\;{\mu}m$ diameter and $250\;{\mu}m$ depth were made by micro electrical discharge machining. The form accuracy and surface roughness of die hole were pretty good and it was shown that the punched hole quality was fine. WC micro-shaft with $30\;{\mu}m$ diameter was made by the multistep micro electro chemical machining. The developed technologies can be effectively used in precision manufacturing of micro punching die and mass production of micro-shaft.

• Tunnel and Underground Space
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• v.5 no.2
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• pp.123-133
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• 1995

A two dimensional visco-plastic finite element model capable of handling the multistep excavaton was developed for investigating the effect of excavation-support sequences on the behaviour of underground openings in the jointed rock mass. Ubiquitous joint pattern was considered in the model and joint properties in each set were assumed to be identical. Passive, fully-grouted rockbolts were considered in the model. Visco-plastic deformations of joints and rockbolts were assumed to be governed by Mohr-Coulomb and von Mises yield criteria, respectively. With the ability of removing elements, the model can von Mises yield criteria, respectively. With the ability of removing elements, the model can simulate the multi-step excavation-support sequences. The reliability of the model to the stability analysis for the underground excavation in practice was checked by simulating the behavior of underground crude oil storage caverns under construction.

• Proceedings of the Korean Vacuum Society Conference
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• 2011.02a
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• pp.203-203
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• 2011

Metastable statates, resonant states in 4s level and excited states in 4p level were investigated with a simple global model and examined by the LIF experiments. Metastable states exhibit an anomalous behavior with the plasma density, on the other hands, other states show monotonous increasing behaviors. It turns out that the metastable state can have such an anomalous behavior due to its special characteristic, electric dipole radiation forbidden. It is expected to resolve the ambiguity of previously reported metastable density behaviors and provide further understanding.

• Proceedings of the Korea Society of Environmental Biology Conference
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• 2004.12a
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• pp.124-126
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• 2004

Molinate is thiocarbamate herbicide used primarily in rice production. Chondrogenesis is a multistep process that is essential for endocondral bone formation. The transcription factor Sox9 has an essential role during the sequential steps of chondrocyte differentiation. Bombina orientalis is one of the most common amphibians in the world and comprises a large proportion of their total number. We examined the embryotoxic and survival effects of molinate at various concentration in B. orientalis embryos. The survival rates of embryos at 312h post fertilization treated with molinate was decreased with concentration dependent manner. Also, developmental malformations appeared by molinate in B. orientalis embryos. the expression levels of Sox9 mRNA was examined by RT-PCR. In our result showed that Sox9 expression was found to be increased in malformed tadpole compared to normal tadpole. These results suggested that molinate was detrimental for survival and development of B. orientalis embryo.

• Bulletin of the Korean Chemical Society
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• v.31 no.11
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• pp.3318-3326
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• 2010

Five new series of 3,4-ethylenedioxythiophene derivatives carrying important pharamacophores, viz., amide, ester, ether and active secondary aryl moieties have been designed and synthesized through multistep reactions starting from thiodiglycolic ester and diethyl oxalate. They have been characterized by elemental and spectral data. All the target compounds have been screened for their anticonvulsant activity at three different models viz. maximal electroshock (MES), subcutaneous metrazole (scMET), and 6 Hz screen and evaluated for their neurotoxicity in rotorod model. Compound 6a emerged as lead with no neurotoxicity. All the five series of compounds are safe in the toxicity studies at the maximum dose of 300 mg/kg of body weight. Amongst the tested compounds, the ester pharmacophore with thioamide fragment has showed better activity than the other analogs.

• Nuclear Engineering and Technology
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• v.47 no.5
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• pp.588-595
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• 2015

This study presents an effective method for additional recovery of residual actinides in liquid electrodes after the electrowinning process of pyroprocessing. The major distinctive feature of this method is a reactor with multiple reaction cells separated by partition walls in order to improve the recovery yield, thereby using the interelement difference in diffusion coefficients within the liquid electrode and controlling the selectivity and purity of element recovery. Through an example of numerical simulation of the diffusion scenarios of individual elements, we verified that the proposed method could effectively separate the actinides (U and Pu) and rare-earth elements contained in liquid cadmium. We performed a five-step consecutive recovery process using a simplified conceptual reaction cell and recovered 58% of the initial amount of actinides (U + Pu) in high purity (${\geq}99%$).

• BMB Reports
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• v.51 no.3
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• pp.157-162
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• 2018

Angiogenesis is a complex, multistep process involving dynamic changes in endothelial cell (EC) shapes and behaviors, especially in specialized cell types such as tip cells (with active filopodial extensions), stalk cells (with less motility) and phalanx cells (with stable junction connections). The Hippo-Yes-associated protein (YAP)/ transcription activator with PDZ binding motif (TAZ) signaling plays a critical role in development, regeneration and organ size by regulating cell-cell contact and actin cytoskeleton dynamics. Recently, with the finding that YAP is expressed in the front edge of the developing retinal vessels, Hippo-YAP/TAZ signaling has emerged as a new pathway for blood vessel development. Intriguingly, the LATS1/2-mediated angiomotin (AMOT) family and YAP/TAZ activities contribute to EC shapes and behaviors by spatiotemporally modulating actin cytoskeleton dynamics and EC junction stability. Herein, we summarize the recent understanding of the role of Hippo-YAP/TAZ signaling in the processes of EC sprouting and junction maturation in angiogenesis.

• Proceedings of the Korean Biophysical Society Conference
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• 1999.06a
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• pp.13-13
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• 1999

"Two-component" phosphorelay signal transduction systems constitute a potential target for antibacterial and antifungal agents, since they are found exclusively in prokaryotes and lower eukaryotes (yeast, fungi, slime mold, and plants) but not in mammalian organisms.(omitted)

• Journal of Korean Society of Water and Wastewater
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• v.13 no.3
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• pp.42-55
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• 1999

A mathematical model for biological nutrient removal in a sequencing batch reactor process, which is based on the IAWQ Activated Sludge Model No. 2 with a few modifications, has been developed. Twenty water quality components and twenty three kinetic equations are incorporated in the model. The model is structured in the matrix form based on the law of mass conservation using stoichiometry and kinetic equations. Stoichiometric coefficients and kinetic parameters included in the model equations are chosen from the literature. A multistep predictor-corrector algorithm of variable step-size is adopted for solving the vector nonlinear ordinary differential equations. The simulation for experimental results is conducted to evaluate the validity of the model and to calibrate coefficients and parameters. The simulation using the model well represents the experimental results from laboratory. The mathematical model developed in this study may be utilized for the design and operation of a sequencing batch reactor process under the steady and unsteady-state at various environmental conditions.