• Journal of Korean Neurosurgical Society
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• 제29권4호
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• pp.550-554
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• 2000

Most extracranial schwannomas are solitary, but neurofibromas are frequently associated with other manietations of neurofibromatosis. Schwannomas that occur within the context of neurofibromatosis tend to be multiple, but multiple schwannomas without manifestation of neurofibromatosis type 2 are very rare. The authors report a very rare case of multiple spinal intradural schwannomas in the absence of neurofibromatosis Type 2 maniestations. A 40-year-old man suffered from longstanding low back pain and left side sciatica which was treated with two stage operations. MRI showed multiple intradural mass lesions extending from L1 vertebral segment to S1 vertebral segment. There were no clinical and radiological manifestations of Type 2 neurofibromatosis. Histologically confirmed diagnosis was schwannoma.

• 대한두개안면성형외과학회지
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• 제21권6호
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• pp.380-383
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• 2020

Schwannomas, which originate from Schwann cells in the peripheral nervous system, are slowg-rowing and uncommon benign tumors. Most schwannomas (90%) occur in isolation, and multiple occurrences are a characteristic feature of neurofibromas. Schwannomas of the nose and nasal tip are particularly unusual. Although a few cases of schwannomas of the sinusoidal tract and nasal septum have been reported, schwannomas arising from the nasal dorsum area and tip are extremely rare. Sensory abnormalities are also a very rare symptom. We excised a schwannoma on the nasal dorsum through direct incision and a schwannoma on the nasal tip through open rhinoplasty. No postoperative complications involving recurrence, hematoma, or infection occurred. The possibility of neurological changes should be considered in cases of an abnormality in the peripheral nervous system. Schwannoma must be kept in mind as a possible cause of neurological changes localized to a specific dermatome, and should always be considered in the differential diagnosis of a mass on the nose.

• Journal of Chest Surgery
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• 제22권3호
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• pp.494-497
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• 1989

Schwannomas are rare and distinctive nerve sheath tumors. They occur commonly along the course of central and peripheral nerves, especially on the skin of the head, neck and extremities. Histologically, they are characterized by Antoni A and Antoni B tissues of high and low cellularity. 2 cases of intrapulmonary Schwannomas were reported worldwide by 1980. We report a case of twenty seven-year-old male patient with intrapulmonary Schwannoma, who had multiple nodules on the skin of the both upper extremities and scrotum with their characteristic findings.

• Journal of Korean Neurosurgical Society
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• 제30권sup1호
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• pp.140-143
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• 2001

We report a case of huge trigeminal schwannoma in a 10-year-old boy with neurofibromatosis type II, extending into the three spaces of the left middle, posterior, and infratemporal fossa. Initially we thought the child had a solitary trigeminal schwannoma, and most of the mass was resected successfully through one-stage operation, cranio-orbito-zygomatic intradural approach. However during the follow-up of the patient we found radiographically other multiple intracranial tumors of bilateral acoustic schwannomas, right trigeminal schwannoma, and foramen magnum tumor. Eventually the patient was diagnosed as neurofibromatosis type II presenting multiple intracranial tumors. We think childhood trigeminal schwannoma, even though in the case of solitary tumor, should be considered as possible initial manifestation of neurofibromatosis type II and that careful follow-up for the possibility of occurrence of other brain tumors such as schwannomas or meningiomas is necessary.

• 대한영상의학회지
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• 제82권1호
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• pp.194-200
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• 2021

신경초종은 슈반세포에서 기원하는 양성 종양이며 말초신경집에서 생기는 가장 흔한 종양이다. 신경초종은 신체 어디에서나 발견될 수 있으나, 보통 머리와 목, 그리고 사지의 굽힘 면에서 흔하게 보일 수 있는 종양이다. 췌장은 신경초종이 드물게 생기는 위치이며 적은 수의 증례가 보고되었다. 보고된 신경초종 증례의 약 3분의 2 정도에서 낭성변화를 동반한다. 따라서 적절한 진단과 치료를 위해서는 췌장에서 발견되는 낭성변화를 동반한 고형 종양의 경우 신경초종이 감별진단에 포함되어야 한다. 이에 저자들은 병리학적으로 진단된 낭성변화를 동반한 췌장의 신경초종을 문헌고찰과 함께 보고하고자 한다.

• 대한정형외과학회지
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• 제54권1호
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• pp.84-89
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• 2019

신경초종은 Schwann 세포에서 기원하는 양성 종양이다. 총상 신경초종은 총상형이나 다결정성의 성장 형태를 보이는 신경초종의 드문 아형이다. 총상 신경초종은 대부분은 피부와 피하조직에 고립성 병변(solitary lesion)을 보이지만 드물게 심부조직 내에 위치하기도 한다. 저자들은 매우 드물게 후경골 신경 및 원위부 분지 신경에서 발생하였으며, 심부조직에 위치하여 골 변형을 동반한 다발성 총상 신경초종이 재발한 1예를 경험하였기에 이를 보고하고자 한다.

• Journal of Korean Neurosurgical Society
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• 제29권9호
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• pp.1238-1242
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• 2000

Spinal schwannomas are usually extramedullary intradural tumors and their intramedullary localizations are thought to be extremely rare. A 60-year-old woman complaining spastic quadriparesis, voiding difficulty and dyspnea was admitted. Her cervical MRI revealed an intramedullary mass in the cervicomedullary junction with multiple cyst which extended from lower cervical to C3 spinal cord. The mass showed a low signal on T1WI, high signal on T2WI with an wall enhancement. The patient underwent a suboccipital craniectomy and C1-2 laminectomy and the cystic tumor was totally removed through a midline myelotomy. The tumor was proved as an intramedullary schwannoma by pathologic examination. The Intramedullary presence of a tumor arising from the cells of the nerve sheath is unusual, because the central nervous system fibers do not contain the Schwann cell. There have been several hypotheses, but none has been accepted universally. This rare tumor is considered as a curable benign neoplasm, and an accurate intraoperative diagnosis and surgically total removal are essential.

• Journal of Korean Neurosurgical Society
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• 제48권4호
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• pp.383-387
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• 2010

Complete removal of three-compartment trigeminal schwannomas is a challenge to neurosurgeons. To expand exposure of each compartment, the combination and modification of skull base approaches are necessary. The 61-year-old woman was admitted with chronic headache. Preoperative magnetic resonance imaging showed $47{\times}50{\times}40\;mm$-sized tumor originating primarily in the middle cranial fossa extended to the posterior and the infratemporal fossa. We performed operation in five stage; 1. Zygomatic osteotomy, 2. Inferior temporal fossa plate removal and foramen ovale opening, 3. Cavernous sinus opening, 4. Tailored anterior petrosectomy, 5. Meckel's cave opening. Combination of skull base surgery should be concerned according to the patient. In this study, extradural basal extension with zygomatic osteotomy, interdural posterior extension with tailored anterior petrosectomy, and intracavemous exploration are reasonable options for remodeling three-compartment lesion into a single compartment. Tailoring of bone resection and exploring through natural pathway between meningeal layers accomplish single-stage operation for complete removal of tumors.

• Journal of Korean Neurosurgical Society
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• 제30권9호
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• pp.1127-1129
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• 2001

The vast majority of schwannomas occur on cranial nerves, and rarely in the retroperitoneum. Solitary schwannoma in the psoas muscle is extremely rare. The authors present a case of retroperitoneal neoplasm in the psoas muscle identified as schwannoma which is not associated with von Recklinghausen's disease. A 68 years old female patient was admitted because of low back pain and weakness at the left leg. CT and MRI revealed a large cystic mass with well-defined margin and multiple internal septation within the left psoas muscle. The tumor was totally extirpated and histologically confirmed as a schwannoma.

• 대한골관절종양학회지
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• 제11권1호
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• pp.105-109
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• 2005

제 2형 신경섬유종증(Neurofibromatosis)의 임상적 특징 없이 말초에 발생한 티넬징후를 보이는 다발성신경초종(Schwannomatosis) 3례를 경험하여 이를 보고하고자 한다. 주증상은 동통이었으며 3예에서 청장년에서 발생하였다. 발생부위는 상완신경총, 슬와부 그리고 수부였다. 상기 환자 모두에서 이명과 현훈 및 시력저하소견 관찰되지 않았으며 가족력은 없었다. 3예에서 모두에서 두부 자기공명영상 촬영상 전정신경초종(Vestibular schwannoma)이 관찰되지 않았다. 병리소견상 신경초종이 확인되었다. 앞으로 더 많은 증례의 수집과 연구로 다발성 신경초종의 임상양상, 임상경과 그리고 유전학적 특징에 대한 추가적인 연구가 필요할 것으로 사료된다.