• Title/Summary/Keyword: Multiple resistance

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Evaluation of the Applicability of CLSM by Numerical Method and Field Test (현장시험과 수치해석에 의한 관거 뒤채움용 CLSM 적용성 평가)

  • Nam, Joongwoo;Byun, Yoshep;Chun, Byungsik
    • Journal of the Korean GEO-environmental Society
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    • v.14 no.7
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    • pp.5-12
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    • 2013
  • The safety and structural integrity of buried pipes are usually at risk from constructing loading and compaction of backfill materials. The backfill material should be strong enough to help resistance and redistribute loads so that the buried pipe remains unaffected. Due to the many problems associated with buried pipes, there have been multiple studies on the development of a sustainable backfill material. In this study, a Controlled Low Strength Material made of coal ash was considered as a buried pipe backfill material. To determine the feasibility and performance of this backfill material, a numerical simulation was conducted with the results confirmed by a field test. Results showed maximum settlement to be 2 mm with the elastic strain of the buried pipe to be about 0.006.

High School Students' Views about Learning and Knowing of Science (고등학생의 과학학습관)

  • Park, Hyun-Ju;Choi, Byung-Soon
    • Journal of The Korean Association For Science Education
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    • v.21 no.1
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    • pp.59-75
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    • 2001
  • While previous studies have recognized and have researched the resistance of students' scientific conception to change and the difficulty of the change of a conception's status, few have investigated the idea of conceptual ecology as a context of conceptual change learning, including the role that affective and motivational aspects might play when students are exposed to conceptual change learning, The present study was conducted to describe in detail high school students' views about learning and knowing science by summarizing of students' conceptual ecologies. The study was interpretive, using multiple data sources to achieve a triangulation of data. Three students from a public high school for boys serve as cases representative of students' views about learning and knowing science. Students' enthusiasm to pursue science was closely connected to their views about learning and knowing science. Students' views about learning and knowing science are influenced by their views regarding science and science class including the nature of knowledge, learning, and their epistemological commitments, They influence students' self-efficacy and motivation on learning science.

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Study of Surges in a Large-Diameter Subteranean Diversion Channel with Multiple Surge Tanks (대심도 지하관로 배수 시스템의 서어징 현상에 관한 연구)

  • Jeong, Gwang-Geun;Yeo, Un-Sik;An, Tae-Jin
    • Journal of Korea Water Resources Association
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    • v.31 no.6
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    • pp.757-768
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    • 1998
  • rate of outflow is equated to the total rate of flow, both the state equation and its linearized equation yield almost identical oscillations of water levels. This shows that effects of pipe resistance on the surges are small, and justifies a free oscillation analysis. Free oscillation equation has six eigen modes of different periods, including a rigid mode which is existed when the pumped rate of outflow differs from the total rate of inflow. The six modes constitute a variety of surges dependent on different inflow and outflow conditions. Presence of the rigid mode needs sophisticated pump operations adjusted to real flood inflows.

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A Profile Tolerance Usage in GD&T for Precision Manufacturing (정밀제조를 위한 기하공차에서의 윤곽공차 사용)

  • Kim, Kyung-Wook;Chang, Sung-Ho
    • Journal of Korean Society of Industrial and Systems Engineering
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    • v.40 no.2
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    • pp.145-149
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    • 2017
  • One of the challenges facing precision manufacturers is the increasing feature complexity of tight tolerance parts. All engineering drawings must account for the size, form, orientation, and location of all features to ensure manufacturability, measurability, and design intent. Geometric controls per ASME Y14.5 are typically applied to specify dimensional tolerances on engineering drawings and define size, form, orientation, and location of features. Many engineering drawings lack the necessary geometric dimensioning and tolerancing to allow for timely and accurate inspection and verification. Plus-minus tolerancing is typically ambiguous and requires extra time by engineering, programming, machining, and inspection functions to debate and agree on a single conclusion. Complex geometry can result in long inspection and verification times and put even the most sophisticated measurement equipment and processes to the test. In addition, design, manufacturing and quality engineers are often frustrated by communication errors over these features. However, an approach called profile tolerancing offers optimal definition of design intent by explicitly defining uniform boundaries around the physical geometry. It is an efficient and effective method for measurement and quality control. There are several advantages for product designers who use position and profile tolerancing instead of linear dimensioning. When design intent is conveyed unambiguously, manufacturers don't have to field multiple question from suppliers as they design and build a process for manufacturing and inspection. Profile tolerancing, when it is applied correctly, provides manufacturing and inspection functions with unambiguously defined tolerancing. Those data are manufacturable and measurable. Customers can see cost and lead time reductions with parts that consistently meet the design intent. Components can function properly-eliminating costly rework, redesign, and missed market opportunities. However a supplier that is poised to embrace profile tolerancing will no doubt run into resistance from those who would prefer the way things have always been done. It is not just internal naysayers, but also suppliers that might fight the change. In addition, the investment for suppliers can be steep in terms of training, equipment, and software.

Evolving Problem Analyses of Recent Marek's Disease (최근 진화하는 마렉병의 원인 분석)

  • Jang, H.K.;Park, Y.M.;Cha, S.Y.;Park, J.B.
    • Korean Journal of Poultry Science
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    • v.34 no.4
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    • pp.301-318
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    • 2007
  • Marek's disease (MD) is a highly contagious lymphoproliferative disease of poultry caused by the oncogenic herpesvirus designated Marek's disease virus (MDV). MD has a worldwide distribution and is thought to cause an annual loss over US$ one billion to the poultry industry. Originally described as a paralytic disease, today MD is mostly manifested as an acute disease with tumors in multiple visceral organs. MD is controlled essentially by the widespread use of live vaccines administered either in ovo into 18-day-old embryos or into chicks immediately after they hatch. In spite of the success of the vaccines in reducing the losses from the disease in the last 30 years, MDV strains have shown continuous evolution in virulence acquiring the ability to overcome the immune responses induced by the vaccines. During this period, different generations of MD vaccines have been introduced to protect birds from the increasingly virulent MDV strains. However, the virus will be countered each new vaccine strategy with ever more virulent strains. In spite of this concern, currently field problem from MD is likely to be controled by strategy of using bivalent vaccine. But, potential risk factors for outbreak of MD are still remained in this condition. The major factors can be thought that improper handling and incorrect administration of the vaccine, infection prior to establishment of immunity, suppression of immune system by environmental stress and outbreaks of more virulent MDV strain by using vaccine and genetic resistance of host.

Study on characteristic for Larson's ratio of water treatment plants (국내 정수장의 Larson's ratio 특성에 관한 연구)

  • Min, Byung-dae;Chung, Hyen-mi;Ahn, Kyung-hee;Park, Ju-hyun
    • Journal of Korean Society of Water and Wastewater
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    • v.30 no.5
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    • pp.579-586
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    • 2016
  • In many countries in order to manage corrosion of water treatment process, it is currently using Langelier index (LI). However, management of the Larson's ratio (LR) to compare corrosion management and LI which can be generated by the water treatment process is required. In this study, in order to ensure data LR, factors associated with the actual corrosion resistance of water treatment plant was measured. Using the measured data, the model equation can be estimated alkalinity, and using the statutory water quality data, LR and alkalinity is estimated. At comparison of the measured value and estimated value of alkalinity, it appeared in $R^2$ = 0.629, using the statutory water quality data and estimated alkalinity model, LR and alkalinity (Whole water treatment plants : 472) is estimated. Concentration of estimated alkalinity is 0.5 mg/L to 107.5 mg/L (average : 23.2 mg/L), and LR is 0.1 to 10 (average : 1.3). At tendency to corrosion of investigated LR, "No metal tendency" (>0.5) is 39 water treatment plants, 8.26 %, and "corrosion metal tendency" is 433 water treatment plants, 91.74%.

Molecular Characterization of Plasmids Encoding CTX-M β-Lactamases and their Associated Addiction Systems Circulating Among Escherichia coli from Retail Chickens, Chicken Farms, and Slaughterhouses in Korea

  • Jo, Su-Jin;Woo, Gun-Jo
    • Journal of Microbiology and Biotechnology
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    • v.26 no.2
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    • pp.270-276
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    • 2016
  • Extended-spectrum β-lactamases (ESBLs), particularly those of the CTX-M types, are the predominant resistance determinants of Escherichia coli that are rapidly spreading worldwide. To determine CTX-M types, E. coli isolates were collected from retail chickens (n = 390) and environmental samples from chicken farms (n = 32) and slaughterhouses (n = 67) in Korea. Fifteen strains harboring blaCTX-M genes were isolated from 358 E. coli isolates. The most common CTX-M type was eight of CTX-M-15, followed by six of CTX-M-1 and one of CTX-M-14. The blaCTX-M genes were identified in the isolates from retail chickens (n = 9), followed by feces, water pipes, floors, and walls. Conjugations confirmed the transferability of the plasmids carrying blaCTX-M genes to the recipient E. coli J53 strain. Furthermore, eight addiction systems carried by the replicons in CTX-M types were confirmed. The dominant system was identified as ccdAB, vagCD, and pndAC in donor strains and transconjugants. The clonal relationship between the two strains carrying blaCTX-M genes indicates that E. coli may transmit from the farm to retail chickens, suggesting a possible public health risk. Our findings demonstrate that the detection of CTX-M types in E. coli isolates is important for tracking ESBL production in animals, and suggest linkage of multiple addiction systems in plasmids bearing blaCTX-M genes.

Genetic Characterization of Atypical Shigella flexneri Isolated in Korea

  • Hong, Sa-Hyun;Choi, Yeon-Hwa;Choo, Yun-Ae;Choi, Young-Woon;Choi, Seon-Young;Kim, Dong-Wook;Lee, Bok-Kwon;Park, Mi-Sun
    • Journal of Microbiology and Biotechnology
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    • v.20 no.10
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    • pp.1457-1462
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    • 2010
  • Three types of serotypically atypical Shigella flexneri isolates were collected between 2007 and 2008 from Korean patients at the Korea National Institute of Health (NIH). These atypical isolates were characterized and compared with serologically typical S. flexneri. The first grouping of 11 atypical isolates displayed agglutination only with polyB antiserum and exhibited no reaction with any typing or grouping sera (PolyB:un). The second group of 3 isolates displayed reactions with typing sera IV, but also did not bind with any grouping sera (IV:un). The third group of 14 isolates exhibited a plural agglutination pattern, reacting with typing sera II, and two grouping sera (II:(3)4,7(8)). Amongst these atypical isolates, isolates belonging to IV:un and II:(3)4,7(8) exhibited greater antibiotic resistance, in particular to ampicillin, streptomycin, and trimethoprim-sulfamethoxazole, than typical S. flexneri strains. Furthermore, all II:(3)4,7(8) strains harbored integrons. This study suggests that these multiple antibiotic-resistant atypical S. flexneri are new subserotypes of S. flexneri that await further serological classification.

Construction of a Shuttle Vector for Protein Secretory Expression in Bacillus subtilis and the Application of the Mannanase Functional Heterologous Expression

  • Guo, Su;Tang, Jia-Jie;Wei, Dong-Zhi;Wei, Wei
    • Journal of Microbiology and Biotechnology
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    • v.24 no.4
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    • pp.431-439
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    • 2014
  • We report the construction of two Bacillus subtilis expression vectors, pBNS1/pBNS2. Both vectors are based on the strong promoter P43 and the ampicillin resistance gene expression cassette. Additionally, a fragment with the Shine-Dalgarno sequence and a multiple cloning site (BamHI, SalI, SacI, XhoI, PstI, SphI) were inserted. The coding region for the amyQ (encoding an amylase) signal peptide was fused to the promoter P43 of pBNS1 to construct the secreted expression vector pBNS2. The applicability of vectors was tested by first generating the expression vectors pBNS1-GFP/pBNS2-GFP and then detecting for green fluorescent protein gene expression. Next, the mannanase gene from B. pumilus Nsic-2 was fused to vector pBNS2 and we measured the mannanase activity in the supernatant. The mannanase total enzyme activity was 8.65 U/ml, which was 6 times higher than that of the parent strain. Our work provides a feasible way to achieve an effective transformation system for gene expression in B. subtilis and is the first report to achieve B. pumilus mannanase secretory expression in B. subtilis.

A Study of Characteristics on the Dissimilar Metals (Alloy steel : A387 Gr. 91 - Carbon Steel : A516 Gr. 70) Welds Made with FCA Multiple Layer Welding: Part 2 (합금강(ASTM A387 Gr. 91) - 탄소강(ASTM A516 Gr.70) 이종금속의 FCA 다층 용접부 특성 평가 : Part. 2)

  • Shin, Tae Woo;Hyun, Jun Hyeok;Koh, Jin Hyun
    • Journal of Welding and Joining
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    • v.35 no.3
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    • pp.68-74
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    • 2017
  • Characteristics of dissimilar metal welds between alloy steel ASTM A387 Gr. 91 and carbon steel ASTM A516 Gr.70 made with Flux cored arc welding(FCAW) have been evaluated in terms of microstructure, mechanical strength, chemical analysis by EDS as well as corrosion test. Three heat inputs of 15.0, 22.5, 30.0kJ/cm were employed to make joints of dissimilar metals with E71T-1C wire. Post-weld heat treatment was carried out at $750^{\circ}C$ for 2.5 h. Based on microstructural examination, Intragranular polygonal ferrite and grainboundary ferrite were formed only in first layer of weld metal. Another layers consisted of acicular ferrite and $Widmannst{\ddot{a}}tten$ ferrite. The amount of acicular ferrite was increased with decreasing heat input and layer. Heat affected zone of alloy steel showed the highest hardness due to the formation of tempered martensite and lower bainite. Lower and upper bainite were formed in heat affected zone of carbon steel. Tensile strengths of dissimilar metal welds decreased with increasing heat inputs. Dissimilar metal welds showed a good hot cracking resistance due to the low HCS index below 4. The salt spray test of dissimilar metals welds showed that the weight loss rate by corrosion below 170 hours was decreased with increasing heat inputs due to the increase of the amount of acicular ferrite.