• Journal of Korean Society of Transportation
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• v.22 no.2 s.73
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• pp.131-143
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• 2004

Given a path represented by a sequence of link numbers in a graph, the vine is differentiated from the loop in a sense that any link number can be visited in the path no more than once, while more than once in the loop. The vine provides a proper idea on complicated travel patterns such as U-turn and P-turn witnessed near intersections in urban transportation networks. Application of the link label method(LLM) to the shortest Path algorithms(SPA) enables to take into account these vine travel features. This study aims at expanding the LLM to a K-th path search algorithm (KPSA), which adopts the node-based-label correcting method to find a group of K number of paths. The paths including the vine type of travels are conceptualized as drivers reasonable route choice behaviors(RRCB) based on non-repetition of the same link in the paths, and the link-label-based MPSA is proposed on the basis of the RRCB. The small-scaled network test shows that the algorithm sequence works correctly producing multiple paths satisfying the RRCB. The large-scaled network study detects the solution degeneration (SD) problem in case the number of paths (K) is not sufficient enough, and the (K-1) dimension algorithm is developed to prevent the SD from the 1st path of each link, so that it may be applied as reasonable alternative route information tool, an important requirement of which is if it can generate small number of distinct alternative paths.

• Korean Journal of Head & Neck Oncology
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• v.17 no.2
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• pp.205-209
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• 2001

Purpose: Most cases of primary hyperparathyroidism are due to parathyroid adenoma or parathyroid hyperplasia. Parathyroid carcinoma is a very rare cause of hyperparathyroidism. Although the diagnosis of parathyroid carcinoma is usually established by pathologic criteria especially of vascular or capsular invasion, some clinical and biochemical features differentiate it from benign forms of hyperparathyroidism. We under-took a retrospective study in 6 patients with parathyroid carcinoma, with the aim of conveying experience from management for this rare cause of hyperparathyroidism. Methods: Clinical symptoms, biochemical laboratory, radiologic, and intraoperative findings, local recurrence and distant metastasis were analyzed in 6 patients diagnosed pathologically as a parathyroid carcinoma after operation from 1992 to 2001. Results: Mean age was 50.2 years (33.0-60.0 years) and male to female ratio was 1:1. Neck mass was found in 5 patients, multiple bone pain in 3 patients and renal stone in 1 patient. One case has suffered from chronic renal failure for 19 years. Although preoperative laboratory evaluations showed the aspects of hyperparathyroidism in all cases, mean serum calcium level was 11.2mg/dl(10.5-12.1mg/dl), slightly elevated. Laboratory values after surgery were within the normal range in 5 cases. However, in one case with chronic renal failure, serum PTH levels, serially checked, were above the normal range. Any of imaging methods failed to suggest a parathyroid carcinoma preoperatively. Parathyroid adenoma was suspected in 3 cases, thyroid cancer in the other cases before surgery. The extent of resection was radical resection of parathyroid lesion with more than unilateral thyroid lobectomy and central compartment neck node dissection and in 2 cases, the resection of recurrent laryngeal nerve or strap muscles was added. During follow-up period, any local or systemic recurrence were not evident in all the cases. Conclusion: Although parathyroid carcinoma is a rare disease and its preoperative diagnosis, in our experience, could not easily be made, the understanding of characteristic clinical and biochemical feature could help diagnosis at first surgery. Radical resection without remaining residual tumor is most important for the management of the parathyroid cancer.

• Journal of KIISE:Computing Practices and Letters
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• v.15 no.10
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• pp.724-739
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• 2009

This paper suggests the energy-efficient message delivery scheme and the software platform which exploits the multiple network interfaces of the mobile terminals and GPS in the current mobile devices. The mobile terminals determine the delivery method among 'direct', 'indirect', and 'WAN' based on the position information of itself and other terminals. 'Direct' method sends a message directly to the target terminal using local RAT. 'Indirect' method extends the service area by exploiting intermediate terminals as relay node. If the target terminal is too far to reach through 'direct' or 'indirect' method, the message is sent using wireless WAN technology. Our proposed scheme exploits the position information and, thus, power consumption is drastically reduced in determining handover time and direction. Network simulation results show that our proposed delivery scheme improves the message transfer efficiency and the handover detection latency. We implemented a message platform in a smart phone realizing the proposed delivery scheme. We compared our platform with other typical message platforms from energy efficiency aspect by observing the real power consumption and applying the mathematical modeling. The comparison results show that our platform requires significantly less power.

• The Journal of the Korea Contents Association
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• v.4 no.4
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• pp.189-196
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• 2004

Most of the recent researches for ATM switches have been based on multistage interconnection network known as regularity and self-routing property. These networks can switch packets simultaneously and in parallel. However, they are blocking networks in the sense that packet is capable of collision with each other Mainly Banyan network have been used for structure. There are several ways to reduce the blocking or to increase the throughput of banyan-type switches: increasing the internal link speeds, placing buffers in each switching node, using multiple path, distributing the load evenly in front of the banyan network and so on. Therefore, this paper proposes the use of recirculating shuffle-exchange network to reduce the blocking and to improve hardware complexity. This structures are recirculating shuffle-exchange network as simplified in hardware complexity and Rank network with tree structure which send only a packet with highest priority to the next network, and recirculate the others to the previous network. after it decides priority number on the Packets transferred to the same destination, The transferred Packets into banyan network use the function of self routing through decomposition and composition algorithm and all they arrive at final destinations. To analyze throughput, waiting time and packet loss ratio according to the size of buffer, the probabilities are modeled by a binomial distribution of packet arrival. If it is 50 percentage of load, the size of buffer is more than 15. It means the acceptable packet loss ratio. Therefore, this paper simplify the hardware complexity as use of recirculating shuffle-exchange network instead of bitonic sorter.

• Journal of KIISE:Information Networking
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• v.31 no.5
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• pp.532-543
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• 2004

Mobile Ad hoc NETworks (MANET) consist of mobile nodes which are usually powered by battery Approaches for minimizing power consumption have been proposed for all network layers and devices. IEEE 802.11 DCF (Distributed Coordination Function), a well-known medium access control protocol for MANETS, also defines a power save mode operation. The nodes in power save mode periodically repeat the awake state and the doze state in synchronized fashion. When all nodes are in the awake state, the exchange the announcements for the subsequent message transmission with neighbors. The nodes that send or receive the announcements stay awake for data transmission, and others go into the dole state. The previous works for enhancing the power save mode operation have focused on shortening the duration of the awake state. We observed that the longer sleeping period results in seriously long delivery latency and the consequent unnecessary power consumption as well, because the packets can move forward only one hop for a fixed interval. In this paper, we propose an improved protocol for the power save mode of IEEE 802.11 DCF, which allows the flooding packets to be forwarded several hops in a transmission period. Our approach does not reduce the duration of compulsory awake period, but maximizes its utilization. Each node propagates the announcements for next flooding to nodes of several hops away, thus the packets can travel multiple hops during one interval. Simulation results of comparison between our scheme and the standard show a reduction in flooding delay maximum 80%, and the unicasting latency with accompanying flooding flows near 50%, with slight increase of energy consumption.

• The Journal of the Korea Contents Association
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• v.15 no.9
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• pp.21-28
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• 2015

In the semi-conductor process, a simulation process is performed to detect defects by analyzing the behavior of the impurity through the physical quantity calculation of the inner element. In order to perform the simulation, Finite-Difference Time-Domain(FDTD) algorithm is used. The improvement of semiconductor which is composed of nanoscale elements, the size of simulation is getting bigger. Problems that a processor such as CPU or GPU cannot perform the simulation due to the massive size of matrix or a computer consist of multiple processors cannot handle a massive FDTD may come up. For those problems, studies are performed with parallel/distributed computing. However, in the past, only single type of processor was used. In GPU's case, it performs fast, but at the same time, it has limited memory. On the other hand, in CPU, it performs slower than that of GPU. To solve the problem, we implemented a computing model that can handle any FDTD simulation regardless of size on the cluster which consist of heterogeneous processors. We tested the simulation on processors using MPI libraries which is based on 'point to point' communication and verified that it operates correctly regardless of the number of node and type. Also, we analyzed the performance by measuring the total execution time and specific time for the simulation on each test.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.31 no.7B
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• pp.679-689
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• 2006

Delivering multicast stream is one of the cost-saving approach in the large scale VOD environment. Because implementing VCR-like interactions for user's convenience in the multicast streaming system involves complex problems, we need the proper solutions for them. In this paper, we propose a hybrid scheme which uses the general P2P and the patching scheme with the Collaborative Interaction Streaming Scheme(CISS). CISS provides jumping functionability to the appropriate multicast session after VCR-like interaction in the environment in which multiple peers transmit VCR-like interaction streams to the VCR-like functionability request node to reduce the loads generated by frequent join or departure of peers at the multicast tree during providing VCR-like functionability. Therefore, with the proposed scheme we can distribute network traffic and reduce control overhead and latency. And to evaluate the performance of proposed scheme we compare it in the aspect of the performance of streaming delivery topology, control overhead and streaming quality with P2Cast[10] and DSL[11]. The simulation result shows that proposed P2Patching reduces about 30% of process overhead and enhances about $25{\sim}30%$ of streaming quality compared with DSL.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.7
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• pp.2819-2826
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• 2015

Combinations of multiple biomarkers representing distinct aspects of metastasis may have better prognostic value for breast cancer patients, especially those in late stages. In this study, we evaluated the protein levels of N-${\alpha}$-acetyltransferase 10 protein (Naa10p), synuclein-${\gamma}$ (SNCG), and phosphatase of regenerating liver-3 (PRL-3) in 365 patients with breast cancer by immunohistochemistry. Distinct prognostic subgroups of breast cancer were identified by combination of the three biomarkers. The Naa10p+SNCG-PRL-3-subgroup showed best prognosis with a median distant metastasis-free survival (DMFS) of 140 months, while the Naa10p-SNCG+PRL-3+subgroup had the worst prognosis with a median DMFS of 60.5 months. Multivariate analysis indicated Naa10p, SNCG, PRL-3, and the TNM classification were all independent prognostic factors for both DMFS and overall survival (OS). The three biomarker combination of Naa10p, SNCG and PRL-3 performed better in patients with lymph node metastasis, especially those with more advanced tumors than other subgroups. In conclusion, the combined expression profile of Naa10p, SNCG and PRL-3, alone or in combination with the TNM classification system, may provide a precise estimate of prognosis of breast cancer patients.

• Journal of Korea Spatial Information System Society
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• v.8 no.2 s.17
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• pp.75-89
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• 2006

LBS (Location-Based Service) systems have become a serious subject for research and development since recent rapid advances in wireless communication technologies and position measurement technologies such as global positioning system. The architecture named the GALIS (Gracefully Aging Location Information System) has been suggested which is a cluster-based distributed computing system architecture to overcome performance losses and to efficiently handle a large volume of data, at least millions. The GALIS consists of SLDS and LLDS. The SLDS manages current location information of moving objects and the LLDS manages past location information of moving objects. In this thesis, we implement a monitoring technique for the GALIS prototype, to allow dynamic load balancing among multiple computing nodes by keeping track of the load of each node in real-time during the location data management and spatio-temporal query processing. We also propose a buffering technique which efficiently manages the query results having overlapped query regions to improve query processing performance of the GALIS. The proposed scheme reduces query processing time by eliminating unnecessary query execution on the overlapped regions with the previous queries.

• Parasites, Hosts and Diseases
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• v.49 no.2
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• pp.115-123
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• 2011

Toxoplasma gondii Korean isolate (KI-1) tachyzoites were inoculated intraduodenally to BALB/c mice using a silicon tube, and the course of infection and immune responses of mice were studied. Whereas control mice, that were infected intraperitoneally, died within day 7 post-infection (PI), the intraduodenally infected mice survived until day 9 PI (infection with $1{\times}10^5$ tachyzoites) or day 11 PI (with $1{\times}10^6$ tachyzoites). Based on histopathologic (Giemsa stain) and PCR (B1 gene) studies, it was suggested that tachyzoites, after entering the small intestine, invaded into endothelial cells, divided there, and propagated to other organs. PCR appeared to be more sensitive than histopathology to detect infected organs and tissues. The organisms spread over multiple organs by day 6 PI. However, proliferative responses of splenocytes and mesenteric lymph node (MLN) cells in response to con A or Toxoplasma lysate antigen decreased significantly, suggesting immunosuppression. Splenic $CD4^+$ and $CD8^+$ T-Iymphocytes showed decreases in number until day 9 PI, whereas IFN-${\gamma}$ and IL-10 decreased slightly at day 6 PI and returned to normal levels by day 9 PI. No TNF-${\alpha}$ was detected throughout the experimental period. The results showed that intraduodenal infection with KI-1 tachyzoites was successful but did not elicit significant mucosal immunity in mice and allowed dissemination of T. gondii organisms to systemic organs. The immunosuppression of mice included reduced lymphoproliferative responses to splenocytes and MLN cells to mitogen and low production of cytokines, such as IFN-${\gamma}$, TNF-${\alpha}$, and IL-10, in response to T. gondii infection.