• 제목/요약/키워드: Multiple Trait Model

검색결과 66건 처리시간 0.032초

고혈압 환자에서 불안증상에 영향을 미치는 정신심리학적 요인 (Psychosocial Factors Influencing Anxiety Symptoms in Patients With Hypertension)

  • 문석현;김승곤;양혜정;서은현;윤형준
    • 대한불안의학회지
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    • 제18권1호
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    • pp.17-25
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    • 2022
  • Objective : The aim of this study was to investigate the prevalence of anxiety symptoms and its association with psychological factors in patients with hypertension. Methods : The Participants included 124 patients with hypertension. Anxiety symptoms were evaluated by the Hospital Anxiety and Depression Scale. Socio-demographics, perceived stress, state-trait anger, life satisfaction, and ego resiliency were assessed. Stepwise multiple regression analyses were carried out to examine the impact of perceived stress, state-trait anger, and life satisfaction on anxiety symptoms. In addition, moderated regression analysis was performed to explore the moderating effect of ego resiliency between perceived stress and anxiety symptoms. Results : A total of 17 subjects (13.7%) were identified as having anxiety symptoms. Higher perceived stress and state-trait anger, and lower life satisfaction were found to be significant correlates of anxiety symptoms. In the final model, higher levels of perceived stress (β=0.378, p<0.001) and trait anger (β=0.320, p<0.001) were related to higher levels of anxiety symptoms, while a higher level of life satisfaction (β=-0.166, p=0.025) was associated with a lower level of anxiety symptoms. Further, ego resiliency buffered the negative effect of perceived stress on anxiety symptoms. Conclusion : This study demonstrated the prevalence of anxiety symptoms and associated psychological factors among patients with hypertension. Our findings suggest that improving life satisfaction and ego-resiliency as well as controlling stress and anger may be important in the management of anxiety symptoms in patients with hypertension.

Genetic parameter analysis of reproductive traits in Large White pigs

  • Yu, Guanghui;Wang, Chuduan;Wang, Yuan
    • Animal Bioscience
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    • 제35권11호
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    • pp.1649-1655
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    • 2022
  • Objective: The primary objective of this study was to determine the genetic parameters for reproductive traits among Large White pigs, including the following traits: total number born (TNB), number born alive (NBA), litter birth weight (LBW), average birth weight (ABW), gestation length (GL), age at first service (AFS) and age at first farrowing (AFF). Methods: The dataset consisted of 19,036 reproductive records from 4,986 sows, and a multi-trait animal model was used to estimate genetic variance components of seven reproductive traits. Results: The heritability estimates for these reproductive traits ranged from 0.09 to 0.26, with the highest heritability for GL and AFF, and the lowest heritability for NBA. The repeatabilities for TNB, NBA, LWB, ABW, and GL were ranged from 0.16 to 0.34. Genetic and phenotypic correlations ranged from -0.41 to 0.99, and -0.34 to 0.98, respectively. In particular, the correlations between TNB, NBA and LBW, between AFS and AFF, exhibited a strong positive correlation. Furthermore, for TNB, NBA, LBW, ABW, and GL, genetic correlations of the same trait between different parities were moderately to strongly correlated (0.32 to 0.97), and the correlations of adjacent parities were higher than those of nonadjacent parities. Conclusion: All the results in the present study can be used as a basis for the genetic assessment of the target population. In the formulation of dam line selection index, AFS or AFF can be considered to combine with TNB in a multiple trait swine breeding value estimation system. Moreover, breeders are encouraged to increase the proportion of sows at parity 3-5 and reinforce the management of sows at parity 1 and parity ≥8.

반복모형을 이용한 한우 초음파 측정형질의 유전모수추정 (Repeated Records Animal Model to Estimate Genetic Parameters of Ultrasound Measurement Traits in Hanwoo Cows)

  • 박철현;구양모;김병우;선두원;김정일;송치은;이기환;이재윤;정용호;이정규
    • Journal of Animal Science and Technology
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    • 제54권2호
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    • pp.71-75
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    • 2012
  • 본 연구는 한우 암소 초음파 측정자료 특징을 알아보고, 측정형질에 대한 유전모수를 추정하여 육질 또는 육량 개량을 위한 기초자료를 제공하기 위해 수행되었으며, 2001년부터 2009년까지 한국종축개량협회에 의해 측정된 한우 암소 36,893두를 이용하였고, 그 중 반복기록이 있는 개체는 7,913두였다. 유전모수 추정을 위하여 반복개체모형을 이용하였으며, 유전모수 추정에는 REMLF90 (Miztal, 2001)을 이용하였다. 유전모수 추정모형의 설정을 위하여 흉위, 영양도 및 초음파 측정치에 대한 출생년도, 출생계절, 측정년도, 측정계절, 측정지역, 측정연령 등의 환경효과를 추정하였다. 반복개체모형으로 추정된 배최장근단면적, 등지방두께 및 근내지방도에 대한 유전력이 각각 0.31, 0.38, 0.27로 나타났고, 다형질개체모형으로 추정한 유전력은 각각 0.02, 0.09, 0.07로 낮게 추정되었다. 반복개체모형을 이용한 반복력은 배최장근단면적, 등지방두께, 근내지방도가 각각 0.46, 0.57, 0.39로 나타났다. 분석모형 간의 추정치의 차이를 비교 할 때 반복모형에서의 유전력과 반복력이 높게 추정되었다. 따라서 반복형질 값을 가진 형질들의 측정치를 표준화하여 한우암소개량을 위한 기초자료로 활용된다면 유전능력평가와 개량사업 비용절감에 도움이 될 것으로 기대된다.

Effect of Number of Lactation Records on the Selection Rates in Holstein Dairy Cattle

  • Cho, Kwang-Hyun;Choy, Yun-Ho;Kong, Hong-Sik;Lee, Hak-Kyo;Kim, Sung-Hoon;Park, Kyung-Do
    • Journal of Animal Science and Technology
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    • 제55권2호
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    • pp.81-85
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    • 2013
  • This experiment was conducted to investigate the effects of lactation records in Holstein dairy cattle on the selection rates using a total of 341,436 test records from 113, 812 heads of cattle from first to third lactation. Heritabilities for milk, fat, and protein yields were highest at first lactation (0.28, 0.24, and 0.27, respectively), and decreased to 0.14, 0.15, and 0.13 at third lactation. For the milk yields, phenotypic correlations between first and second lactation, first and third lactation, and second and third lactation were low (0.49, 0.39, and 0.47, respectively), while genetic correlations among consecutive lactations and between second and third were above 0.8 and 0.9. In Model I, of the 1,138 heads the top 1% were selected based on first lactation records, only 32.4% (396 heads) were re-selected when the second lactation records were included and the 67.6% (769 heads) were newly selected animals. While in Model II, 85.1% (1,138 heads) of the animals which were selected as the top 1% on the basis of first and second lactation records were included. A multiple trait evaluation method using multiple lactation records is more desirable than a single trait evaluation method using first lactation records only.

Genetic Relationship between Carcass Traits and Carcass Price of Korean Cattle

  • Kim, Jong-Bok;Kim, Dae-Jung;Lee, Jeong-Koo;Lee, Chae-Young
    • Asian-Australasian Journal of Animal Sciences
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    • 제23권7호
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    • pp.848-854
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    • 2010
  • The objectives of this study were to estimate genetic parameters for the carcass price and carcass traits contributing to carcass grading and to investigate the influence of each carcass trait on the carcass price using multiple regression and path analyses. Data for carcass traits and carcass prices were collected from March 2003 to January 2009 on steers of Korean cattle raised at private farms. The analytical mixed animal model, including slaughter house-year-month combination, linear and quadratic slaughter age as fixed effects and random animal and residual effects, was used to estimate genetic parameters. The effects of carcass traits on the carcass price were evaluated by applying multiple regression analyses. Heritability estimates of carcass traits were $0.20{\pm}0.08$ for carcass weight (CWT), $0.33{\pm}0.10$ for back fat thickness (BFT), $0.07{\pm}0.05$ for eye-muscle area (EMA) and $0.25{\pm}0.10$ for marbling score (MS), and those of carcass prices were $0.21{\pm}0.10$ for auction price per 1 kg of carcass weight (AP) and $0.13{\pm}0.07$ for total price (CP). Genetic correlation coefficients of AP with CWT and MS were $-0.35{\pm}0.29$ and $0.99{\pm}0.04$, respectively, and those of CP with CWT and MS were $0.59{\pm}0.22$ and $0.39{\pm}0.29$ respectively. If an appropriate adjustment for temporal economic value is available, the moderate heritability estimates of AP and CP might suggest their potential use as the breeding objectives for improving the gross incomes of beef cattle farms. The large genetic correlation estimates of carcass price variables with CWT and MS implied that simultaneous selection for both CWT and MS would be also useful in enhancing income.

구성 타당성 평가방법에 관한 연구 (A Study on the Methods for Assessing Construct Validity)

  • 이광희;이선규;장성호
    • 산업경영시스템학회지
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    • 제22권50호
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    • pp.1-9
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    • 1999
  • The purpose of this study is to establish a basis for assessing construct validity of measures used in organizational research. The classic Campbell and Fiske's(1959) criteria are found to be lacking in their assumptions, diagnostic information, and power. The inherent confounding of measurement error with systematic trait and method effects is a severe limitation for a proper interpretation of convergent and discriminant validity. The confirmatory factor analysis(CFA) approach overcomes most of the limitations found in Campbell and Fiske's(1959) method. However, the CFA approach confounds random error with unique variance specific to a measure. The second-order confirmatory factor analysis(SOCFA) was shown to harbor rather restrictive assumptions and is unlikely to be met in practice. The first-order, multiple-informant, multiple-item(FOMIMI) model is a viable option, but it may also be of limited use because of the large number measures.

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청소년의 적응에 영향을 미치는 가족체계모델개발에 관한 연구 (An Exploratory Study of Developing Model on Family System Related to Adolescent Adjustment)

  • 전귀연
    • 대한가정학회지
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    • 제34권3호
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    • pp.137-155
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    • 1996
  • The purpose of this study was to identify the relative influence of OCM and BSM's family functioning dimensions and develop a new family system model related to adolescent adjustment. The 443 subjects were selected randomly from the second grade of middle and high schools in the city of Taegu. The survey instruments were FACESⅢ, SFI-Ⅱ, State-Trait Anxiety Inventory, Depression Scale, Self-Esteem Scale, and Delinquency Scale, Factor Analysis, Cronbach's α, Multiple Regression, MANOVA, Scheffe test were conducted for the data analysis. The major findings of this study were as follows: First, OCM's and BSM's family functioning dimensions respectively had different relative influence that affected adolescent adjustment level. In anxiety and depression. BSM's family health/competence dimension had superior influence to any other family functioning dimensions and in self-esteem and delinquency, OCM's cohesion dimension was superior to any other family functions. Second, family system classification method by a new family system model using family cohesion(OCM's relationship dimension) and family health/competence(BSM's change dimension) was more useful than OCM in evaluating adolescent adjustment.

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벤처기업 최고경영자의 성격특성과 경영전략간의 관계 (The Relationship between Personality Trait of Venture CEO and Corporate Strategy)

  • 임창희;김영천
    • 정보학연구
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    • 제4권2호
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    • pp.51-68
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    • 2001
  • 본 연구는 벤처기업 최고경영자의 성격특성이 경영전략에 미치는 영향을 살펴보기 위한 것이다. 성격특성은 크게 성격타입, 통제위치(locus of control), 위험감수성향 등 세 가지로 나누었으며, 이러한 성격특성의 차이에 따라서 공격형 전략을 선택하는가, 방어형 전략을 선택하는가를 측정하였다. 서울·경기지역의 벤처기업협회에 등록되어 있는 벤처기업을 대상으로 설문을 배포하여 유효한 87개 샘플을 분석대상으로 삼았다. 연구결과 A형 성격일수록, 내재론자일수록 그리고 위험감수성이 강할수록 공격적인 진입전략을 선택하고, B형 성격일수록, 외재론자일수록 그리고 위험회피성이 강할수록 방어적인 틈새시장 전략을 선택한다는 결과가 도출되었다. 또한 다중회귀모형을 통하여 독립변수의 상대적 중요도를 검증한 결과, 통제위치와 위험감수성 변수가 성격타입보다는 경영전략의 선택에 더 영향을 미치는 것으로 조사되었다.

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다변량 모체효과 모형을 이용한 돼지 경제형질의 분산성분 추정 (Estimation of Variance Component on Swine Economic Traits using Multivariate Maternal Animal Model)

  • 박종원;김병우;김시동;장현기;전진태;공일근;이정규
    • 농업생명과학연구
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    • 제44권2호
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    • pp.29-38
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    • 2010
  • 본 연구에서는 2000년부터 2008년 사이에 출생한 Duroc종, Landrace종 및 Yorkshire종 종돈의 총 31,455두의 농장검정 자료를 이용하여 다형질 동물 모형과 다변량 모체효과 모형에 의한 돼지 경제형질의 유전적 분산성분을 추정하였다. 품종별 조사된 각 형질에 있어서 다변량 모체효과 모형을 이용하여 추정된 상가적 효과에 의한 유전력이 모체효과에 의한 유전력보다 모두 높게 나타났으며, 다형질 동물 모형에서 상가적 효과만 고려했을 때의 유전력이 다변량 모체효과 모형에서 추정된 상가적 효과의 의한 유전력보다 대부분 높게 추정되었다. 다변량 모체효과 모형을 이용하여 추정된 모체효과에 의한 육종가와 표현형가와의 상관관계에 있어서 대부분 낮은 정(+)의 상관이거나 강한 부(-)의 상관관계를 보여 품종별 각 형질에 있어서 모체효과를 적절히 고려하여 육종가와 표현형의 상관관계를 높인다면 보다 나은 개량을 도모 할 수 있을 것으로 사료된다.

Multiple Linkage Disequilibrium Mapping Methods to Validate Additive Quantitative Trait Loci in Korean Native Cattle (Hanwoo)

  • Li, Yi;Kim, Jong-Joo
    • Asian-Australasian Journal of Animal Sciences
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    • 제28권7호
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    • pp.926-935
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    • 2015
  • The efficiency of genome-wide association analysis (GWAS) depends on power of detection for quantitative trait loci (QTL) and precision for QTL mapping. In this study, three different strategies for GWAS were applied to detect QTL for carcass quality traits in the Korean cattle, Hanwoo; a linkage disequilibrium single locus regression method (LDRM), a combined linkage and linkage disequilibrium analysis (LDLA) and a $BayesC{\pi}$ approach. The phenotypes of 486 steers were collected for weaning weight (WWT), yearling weight (YWT), carcass weight (CWT), backfat thickness (BFT), longissimus dorsi muscle area, and marbling score (Marb). Also the genotype data for the steers and their sires were scored with the Illumina bovine 50K single nucleotide polymorphism (SNP) chips. For the two former GWAS methods, threshold values were set at false discovery rate <0.01 on a chromosome-wide level, while a cut-off threshold value was set in the latter model, such that the top five windows, each of which comprised 10 adjacent SNPs, were chosen with significant variation for the phenotype. Four major additive QTL from these three methods had high concordance found in 64.1 to 64.9Mb for Bos taurus autosome (BTA) 7 for WWT, 24.3 to 25.4Mb for BTA14 for CWT, 0.5 to 1.5Mb for BTA6 for BFT and 26.3 to 33.4Mb for BTA29 for BFT. Several candidate genes (i.e. glutamate receptor, ionotropic, ampa 1 [GRIA1], family with sequence similarity 110, member B [FAM110B], and thymocyte selection-associated high mobility group box [TOX]) may be identified close to these QTL. Our result suggests that the use of different linkage disequilibrium mapping approaches can provide more reliable chromosome regions to further pinpoint DNA makers or causative genes in these regions.