• Communications for Statistical Applications and Methods
• /
• v.13 no.3
• /
• pp.567-576
• /
• 2006

In this paper, we applied the multiblock dimension reduction methods to the classification of tumor based on microarray gene expressions data. This procedure involves clustering selected genes, multiblock dimension reduction and classification using linear discrimination analysis and quadratic discrimination analysis.

• Macromolecular Research
• /
• v.10 no.2
• /
• pp.67-74
• /
• 2002

New immunoprotecting membranes were prepared by spin coating the amphiphilic random multiblock copolymers of poly(ethylene glycol) (PEG) and poly(tetramethylene ether glycol) (PTMEG) or poly(dimethyl siloxane) (PDMS) on porous Durapore(R) membrane. The copolymer coating was intended to make a biocompatible, immunoprotecting diffusional barrier and the supporting porous substrate was for mechanical stability and processability. By filling Durapore(R) membrane pores with water, the penetration of coating solution into the pores was minimized during the spin coating process. A single coating process produced a completely covered thin surface layer (~1 ${\mu}{\textrm}{m}$ in thickness) on the porous substrate membrane. The permselectivity of the coated layer was influenced by PEG block length, polymer composition, and thickness of the coating layer. A composite membrane with the coating layer prepared with PEG 2 K/PTMEG 2 K block copolymer showed that its molecular weight cut-of fat any 40 based on dextran was close to the molecular size of IgG (Mw = 150 kDa). However, IgG permeation was detected from protein permeation test, while glucose oxidase (Mw = 186 kDa) was not permeable through the coated membrane.

• 한국전산유체공학회:학술대회논문집
• /
• 1995.10a
• /
• pp.110-110
• /
• 1995

• Journal of computational fluids engineering
• /
• v.9 no.2
• /
• pp.62-69
• /
• 2004

The present work solved 3D incompressible RANS equations on a rotating, multi-blocked grid system to efficiently analyze ducted marine propulsor with the interaction of propeller guidevane and annular duct. To handle the interface boundary between the guidevane and the propeller, a sliding multiblock technique based on the cubic spline interpolation was applied. To validate the present code, a turbine flow was simulated and the time-averaged pressure coefficients were compared with experiment. After the code validation, the flowfield around a ducted marine propeller with pre-swirl guidevane was simulated.

• 유체기계공업학회:학술대회논문집
• /
• 2001.11a
• /
• pp.293-299
• /
• 2001

Since the previous cut-and-try design algorithm require much cost and time, it has recently been concerned the automatic design technique using the CFD and optimum design algorithm. In this study, the Navier-Stokes equations is solved to consider the more detail viscous flow informations of cascade interaction and O-H multiblock grid system is generated to impose an accurate boundary condition. The cubic-spline interpolation is applied to handle a relative motion of a rotor to the stator. To validate present procedure, the time averaged aerodynamic loads are compared with experiment and good agreement obtained. Once the N-S equations have been solved, the computed aerodynamic loads may be used to computed the sensitivities of the aerodynamic objective function. The Modified Method of feasible Direction(MMFD) is usef to compute the

• 한국전산유체공학회:학술대회논문집
• /
• 1998.05a
• /
• pp.174-180
• /
• 1998

Numerical study of three-dimensional turbulent flow in a forward curved centrifugal fan is presented. Standard $k-{\varepsilon}$ turbulence model and non-orthogonal curvilinear coordinates are used to consider the turbulent flow field and complex geometry. Finite Volume approach is adopted for discretization scheme and structured grid system is used to help convergence. Multiblock grid system is used for flow field and divided into five domains that are inlet, outlet, impeller, tip clearance and scroll. It is assumed that the flow field is steady state and incompressible. This numerical work is performed with commercial CFD-ACE code developed by CFD Research Corporation, and the results are compared wi th the experimental data

• Macromolecular Research
• /
• v.16 no.7
• /
• pp.596-603
• /
• 2008

To improve the mechanical properties, dimensional stability and blood compatibility, the biomedical material $Pellethene^{(R)}$ was blended with multiblock polyurethane (MPU) containing phospopholipid/long alkyl chain (C-18) at the various MPU contents and crosslinked using dicumyl peroxide as a crosslinking agent. The maximum MPU content for stable $Pellethene^{(R)}$/MPU blended films was approximately 30 wt%. The optimum crosslinking agent content and crosslinking time with respect to the mechanical properties were 4 wt% and 3 h, respectively. The mechanical properties (tensile strength and elongation at break) and water absorption of the crosslinked blend film increased with increasing MPU content. The test of platelet adhesion on the surfaces of the crosslinked blend film showed a decrease in the level of platelet adhesion from 70% to 6% with increasing MPU content from 0 to 30 wt%. These results suggest that the crosslinked $Pellethene^{(R)}$/MPU-30 (MPU content: 30 wt%) sample has strong potential as a novel material for blood compatible material applications.

• 한국전산유체공학회:학술대회논문집
• /
• 2003.08a
• /
• pp.188-193
• /
• 2003

The present work solved 3D incompressible RANS equation on a rotating, non-orthogonal multi-blocked grid system to efficiently analyze ducted marine propulsor with rotor-stator interaction. To handle the interface boundary between a rotor and a stator maintaining the conservative property, the sliding multiblock technique using the cubic spline interpolation and the bilinear interpolation technique were applied. To validate present code, a turbine flow having rotor- stator interaction was simulated. Time averaged pressure coefficients were compared with experiments and good agreement was obtained. After the code validation, the flowfield around a single-stage ducted marine propulsor was simulated.

• Journal of Power System Engineering
• /
• v.2 no.1
• /
• pp.39-44
• /
• 1998

Computational grids used in the numerical simulation of multi staged turbomachinery flow fields are generated. A multiblock structure simplifies the creation of structured H-grids about complex turbomachinery geometries and facilitate the creation of a grid for multi-row topologies. The numerical algorithm adopts the combination of the algebraic and elliptic method to create the internal grids efficiently and quickly. The input module is made of the results of the preliminary design, i.e., flow-path, aerodynamic conditions along the spanwise direction, and the blade profile data. The final grids generated from each module of the system are used as the preprocessor for the performance prediction of the single row cascades and the flow simulation inside the multi staegd blade passage. Application to low pressure compressor of industrial gas turbine engines was demonstrated to be very reliable and practical in support of design activities.

• Bulletin of the Korean Chemical Society
• /
• v.21 no.4
• /
• pp.383-388
• /
• 2000

Multiblock copolymers consisting of poly( g-benzyl L-glutamate) (PBLG) as the hydrophobic part and poly(ethylene oxide) (PEO) as the hydrophilic part (GEG) were synthesized and characterized. GEG polymeric micelles were prepared by the dialysis technique. Particle size distributions based on intensity,volume, and number-average were 22.6 $\pm$ 11.9 nm, 23.5 $\pm$ 4.6 nm, and 23.7 $\pm$ 37 nm, respectively. It was observed that par-ticle size and size distribution of GEG polymeric micelles changed significantly with the choice of initial sol-vent. Transmission electron micrographs (TEM) showed the polymeric micelles to be spherically shaped, with sizes ranging from 20 nm to 40 nm in diameter. Fluorescence spectroscopy measurements suggested that GEG block copolymers wereassociated in water to form polymeric micelles, and the critical micelle concentrations (CMC) value of the block copolymers was 0.0094 g/L. Further evidenceof micelle formation of GEG block copolymers and limited mobility of the PBLG chain in the core ohe micelle was obtained with 1 H NMR in D2O.