• Journal of the Korea Academia-Industrial cooperation Society
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• v.18 no.6
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• pp.330-335
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• 2017

The demand for electric motor fuel cells has surged in the automotive industry, leading to a recent increase in the demand for square aluminum cans used as fuel cell battery casings. The air vent located on the bottom of the rectangular battery casing prevents large explosions by intermittent pressure release prior to the accumulation of abnormally high pressures. Conventionally, the square cup battery casing is produced via six-step deep drawing, with the outer shape of the vent being manufactured by welding to the square battery casing. On the other hand, this study directly incorporated the air vent outlet into the bottom surface of the rectangular casing. The product of a coupled finite element analysis technique applying the thickness and contour generated from the square cup multi-step deep drawing formation analysis was used as the forging input shape. The results yielded increased prediction accuracy and the advanced prediction of defects, such as swelling and fracture. Based on the results of the initial analyses, two of the generated forging shapes were determined to be suitable, with the optimal forging shape being determined by molding analysis. The results presented here were validated by mold fabrication and a subsequent comparison of the actual and analytical results.

• Journal of Life Science
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• v.21 no.7
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• pp.947-952
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• 2011

A number of epidemiological studies have identified human papillomavirus (HPV) types 1, 2, 3, 4, 7, 10, 27, 57, and 65 in cutaneous common warts. However, identification of the HPV subtype by conventional polymerase chain reaction (PCR) is time consuming with its multi-step laboratory process. In this study, we aim to develop a specific one-step multiplex polymerase chain reaction method which capably identifies six different HPV genotypes related to common warts. By HPV DNA sequence analysis, 6 pairs of specific primers were designed from the intergenic regions of genes L1 to E6, and from genes E2 to L2. DNA sequence analysis with the L1 gene sequence of the sample was performed to measure the specificity of multiplex PCR. HPV-1, -2, -3, -4, -27, and -57 were identified without cross amplification in 109 out of 129 samples. The sensitivity and specificity of our set of primers in detecting HPV were 85% and 99.5%, respectively. For the 20 samples where HPV type was not identifiable by our batch of primer sets, multiplex PCR with an additional set of HPV primers was done, where 7 were found positive for HPV-7 or -65. Our results demonstrate that the newly designed multiplex PCR can rapidly detect the specific HPV subtype involved in common warts with high accuracy.

• Journal of the Korea Convergence Society
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• v.12 no.8
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• pp.31-37
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• 2021

As the size of buildings increases due to urbanization due to the development of industry, the need to purify the air and maintain a comfortable indoor environment is also increasing. With the development of monitoring technology for refrigeration systems, it has become possible to manage the amount of electricity consumed in buildings. In particular, refrigeration systems account for about 40% of power consumption in commercial buildings. Therefore, in order to develop the refrigeration system failure diagnosis algorithm in this study, the purpose of this study was to understand the structure of the refrigeration system, collect and analyze data generated during the operation of the refrigeration system, and quickly detect and classify failure situations with various types and severity . In particular, in order to improve the classification accuracy of failure types that are difficult to classify, a three-step diagnosis and classification algorithm was developed and proposed. A model based on SVM and LGBM was presented as a classification model suitable for each stage after a number of experiments and hyper-parameter optimization process. In this study, the characteristics affecting failure were preserved as much as possible, and all failure types, including refrigerant-related failures, which had been difficult in previous studies, were derived with excellent results.

• Journal of the Korean Ceramic Society
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• v.41 no.6
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• pp.456-463
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• 2004

To enhance the performance of anode-supported SOFC, single cell fabrication procedure was changed for better and resulting power generating characteristics of single cell were investigated. Liquid condensation process was employed for the granulation of NiO/YSZ powder mixture and the produced powder granules were compacted into anode green substrate by uni-axial pressing. YSZ electrolyte was printed on green substrate via screen-printing method and co-fired at 1400$^{\circ}C$ for 3 h. LSM/YSZ composite cathode of which the composition and heat treatment condition was adjusted to minimize the polarization#resistance with AC-impedance spectroscopy, was screen printed. The final single cell size from this multi-step procedure was 5${\times}$5 $\textrm{cm}^2$ and 10${\times}$10 $\textrm{cm}^2$. The maximum power densities of 5${\times}$5 and 10${\times}$10 single cells were about 0.45 W/$\textrm{cm}^2$ and 0.22 W/$\textrm{cm}^2$ at 800$^{\circ}C$, which are two times superior than those from single cells fabricated by the conventional process in previous our work.

• Journal of Environmental Science International
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• v.18 no.6
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• pp.645-654
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• 2009

Lab-scale Electrodialysis(ED) system with different membranes combined with before or after pyroma process were carried out to remove nitrate from two pickling acid wastewater containing high concentrations of $NO_3\;^-$(${\approx}$150,000 mg/L) and F($({\approx}$ 160,000 mg/L) and some heavy metals(Fe, Ti, and Cr). The ED system before Pyroma process(Sample A) was not successful in $NO_3\;^-$ removal due to cation membrane fouling by the heavy metals, whereas, in the ED system after Pyroma process(Sample B), about 98% of nitrate was removed because of relatively low $NO_3\;^-$ concentration (about 30,000 mg/L) and no heavy metals. Mono-selective membranes(CIMS/ACS) in ED system have no selectivity for nitrate compared to divalent-selective membranes(CMX/AMX). The operation time for nitrate removal time decreased with increasing the applied voltage from 10V to 15V with no difference in the nitrate removal rate between both voltages. Nitrate adsorption of a strong-base anion exchange resin of $Cl\;^-$ type was also conducted. The Freundlich model($R^2$ > 0.996) was fitted better than Langmuir mode($R^2$ > 0.984) to the adsorption data. The maximum adsorption capacity ($Q^0$) was 492 mg/g for Sample A and 111 mg/g for Sample B due to the difference in initial nitrate concentrations between the two wastewater samples. In the regeneration of ion exchange resins, the nitrate removal rate in the pickling acid wastewater decreased as the adsorption step was repeated because certain amount of adsorbed $NO_3\;^-$ remained in the resins in spite of several desorption steps for regeneration. In conclusion, the optimum system configuration to treat pickling acid wastewater from stainless-steel industry is the multi-processes of the Pyroma-Electrodialysis-Ion exchange.

• Journal of the Korea Society of Computer and Information
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• v.15 no.11
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• pp.143-156
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• 2010

Faced with an increase of malicious threats from the Internet as well as local area networks, many companies are considering deploying a security system. To help a decision maker select a suitable security tool, this paper proposed a three-step integrated framework using linear fuzzy regression (LFR) and physical programming (PP). First, based on the experts' estimations on security criteria, analytic hierarchy process (AHP) and quality function deployment (QFD) are employed to specify an intermediate score for each criterion and the relationship among these criteria. Next, evaluation value of each criterion is computed by using LFR. Finally, a goal programming (GP) method is customized to obtain the most appropriate security tool for an organization, considering a tradeoff among the multi-objectives associated with quality, credibility and costs, utilizing the relative weights calculated by the physical programming weights (PPW) algorithm. A numerical example provided illustrates the advantages and contributions of this approach. Proposed approach is anticipated to help a decision maker select a suitable security tool by taking advantage of experts' experience, with noises eliminated, as well as the accuracy of mathematical optimization methods.

• Applied Chemistry for Engineering
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• v.31 no.4
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• pp.443-451
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• 2020

In this study, the physico-chemical properties and pyrolysis kinetics of livestock mature solid fuel were investigated to know its feasibility as a fuel. Ultimate and proximate analysis results showed that livestock mature solid fuel has high contents of volatile matter (64.94%), carbon (44.35%), and hydrogen (5.54%). The low heating value of livestock mature solid fuel (3880 kcal/kg) was also higher than the standard requirement of solid fuel (3000 kcal/kg). Thermogravimetic analysis results indicated that livestock mature solid fuel has three decomposition temperature regions. The first temperature zone (130~330 ℃) was consisted with the vaporization of extracts and the decomposition of hemicellulose and cellulose. The second (330~480 ℃) and third (550~800 ℃) temperature regions were derived from the decomposition of lignin and additional decomposition of carbonaceous materials, respectively. The activation energy derived from model free kinetic analysis results including Friedman, Flynn-Wall-Ozawa (FWO), and Kissinger-Akahira-Sunose (KAS) methods for the pyrolysis of livestock mature solid fuel was in the range of 173.98 to 525.79 kJ/mol with a conversion rate of 0.1 to 0.9. In particular, the activation energy increased largely at the higher conversion than 0.6. The kinetic analysis using a curve-fitting method suggested that livestock mature solid fuel was decomposed via a multi-step reaction which can be divided into five decomposition steps.

• Geomechanics and Engineering
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• v.20 no.6
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• pp.537-546
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• 2020

Oil and natural gas reserves have been recognised abundantly in clayey rich rock formations in deep costal reservoirs. It is necessary to understand the sedimentary history of those reservoir rocks to well explore these natural resources. This work designs a group of laboratory experiments to mimic the physical process of the sedimentary clay-rich rock formation. It presents characterisation results of the physical properties of the artificial clayey rocks synthesized from illite clay, quartz sand and brine water by high-pressure consolidation tests. Special focus is given on the effects of illite clay content and high-stress consolidation on the physical properties. Multi-step loaded consolidation experiments were carried out with stress up to 35 MPa on mixtures constituting of the illite clay, quartz sand and brine water with five initial illite clay contents (w=85%, 70%, 55%, 40% and 25%). Compressibility and void ratio were characterised throughout the physical compaction process of the mixtures constituting of five illite clay contents and their water permeability was measured as well. Results show that the applied stress induces a great reduction of clayey rock void ratio. Illite clay contents has a significant influence on the compressibility, void ratio and the permeability of the physically synthesized clayey rocks. There is a critical illite clay content w=70% that induces the minimum void ratio in the physically synthesised clayey rocks. The SEM study indicates, in the high-pressure synthesised clayey rocks with high illite clay contents, the illite clay minerals are located in layers and serve as the material matrix, and the quartz minerals fill in the inter-mineral pores or are embedded in the illite clay matrix. The arrangements of the minerals in microscale originate the structural anisotropy of the high-pressure synthesised clayey rock. The test findings can give an intuitive physical understanding of the deep-buried clayey rock basins in energy reservoirs.

• Composites Research
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• v.26 no.6
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• pp.363-372
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• 2013

Numerical simulation for Resin Transfer Molding manufacturing process is attempted by using the eXtended Finite Element Method (XFEM) combined with the level set method. XFEM allows to obtaining a good numerical precision of the pressure near the resin flow front, where its gradient is discontinuous. The enriched shape functions of XFEM are derived by using the level set values so as to correctly describe the interpolation with the resin flow front. In addition, the level set method is used to transport the resin flow front at each time step during the mold filling. The level set values are calculated by an implicit characteristic Galerkin FEM. The multi-frontal solver of IPSAP is adopted to solve the system. This work is validated by comparing the obtained results with analytic solutions. Moreover, a localization method of XFEM and level set method is proposed to increase the computing efficiency. The computation domain is reduced to the small region near the resin flow front. Therefore, the total computing time is strongly reduced by it. The efficiency test is made with a simple channel flow model. Several application examples are analyzed to demonstrate ability of this method.

• KSBB Journal
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• v.21 no.2
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• pp.133-139
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• 2006

In 'solid-phase' PEGylation, the conjugation reaction occurs as the proteins are attached to a solid matrix, and thus it can have distinct advantages over the conventional, solution-phase process. We report a case study: rhIFN-${\alpha}$-2a was first adsorbed to cation exchange resin and then N-terminally PEGylated by aldehyde mPEG of 5, 10, and 20 kD through reductive alkylation. After the PEGylation, salt gradient elution efficiently recovered the mono-PEGylate in a purified form from the unwanted species such as unmodified IFN, unreacted PEG, and others. The mono-PEGylation and its purification were integrated in a single chromatographic step. Depending on the molecular weight of the mPEG aldehyde used, the mono-PEGylation yield ranged 50-64%. We could overcome the major problems of random, or uncontrollable, multi-PEGylation and the post-PEGylation purification difficulties associated with the solution-phase process. N-terminal sequencing and MALDI-TOF MS confirmed that a PEG molecule was conjugated only to the N-terminus. Compared with the unmodified IFN, the mono-PEGylate showed the reduced anti-viral activity as measured by the cell proliferation assay. The bioactivity was reduced more as the higher molecular weight PEG was conjugated. Immunoreactivity, evaluated indirectly by antibody binding activity using a surface plasmon resonance biosensor, also decreased. Nevertheless, trypsin resistance as well as thermal stability was considerably improved.