• Nutrition Research and Practice
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• 제16권sup1호
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• pp.113-125
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• 2022

In the current years, it has now become necessary to establish standards for micronutrient intake based on scientific evidence. This review discusses issues related to the development of the 2020 Dietary Reference Intakes for Koreans (KDRI) for magnesium (Mg), zinc (Zn), and copper (Cu), and future research directions. Following issues were encountered when establishing the KDRI for these minerals. First, characteristics of Korean subjects need to be applied to estimate nutrient requirements. When calculating the estimated average requirement (EAR), the KDRI used the results of balance studies for Mg absorption and factorial analysis for Zn, which is defined as the minimum amount to offset endogenous losses for Zn and Mg. For Cu, a combination of indicators, such as depletion/repletion studies, were applied, wherein all reference values were based on data obtained from other countries. Second, there was a limitation in that it was difficult to determine whether reference values of Mg, Zn, and Cu intakes in the 2020 KDRI were achievable. This might be due to the lack of representative previous studies on intakes of these nutrients, and an insufficient database for Mg, Zn, and Cu contents in foods. This lack of database for mineral content in food poses a problem when evaluating the appropriateness of intake. Third, data was insufficient to assess the adequacy of Mg, Zn, and Cu intakes from supplements when calculating reference values, considering the rise in both demand and intake of mineral supplements. Mg is more likely to be consumed as a multi-nutrient supplement in combination with other minerals than as a single supplement. Moreover, Zn-Cu interactions in the body need to be considered when determining the reference intake values of Zn and Cu. It is recommended to discuss these issues present in the 2020 KDRI development for Mg, Zn, and Cu intakes in a systematic way, and to find relevant solutions.

• 한국광물학회지
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• 제31권3호
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• pp.161-172
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• 2018

멀티 앤빌 프레스(multi-anvil press)는 일반적으로 5-25 GPa의 압력범위와 ${\sim}2,300^{\circ}C$의 온도범위를 구현할 수 있는 고압 기기로, 지구과학에서는 상부맨틀-맨틀전이대까지의 지구 구성물질의 구조를 연구하는 데 도움이 된다. 본 연구에서는 광물의 상전이를 이용한 멀티 앤빌 프레스에 대한 압력-부하 보정(pressure-load calibration) 과정을 소개하고, 시료실(sample chamber) 내에 존재할 수 있는 온도구배에 대해서 논의하였다. 압력-부하 보정은 14/8 G2, 14/8 step, 14/8 HT 조립세트(assembly set)와 18/12 조립세트에 대해 1,100톤 멀티 앤빌 프레스를 이용하여 수행했다. 초기 물질로 석영, 규회석구조의 $CaGeO_3$, 포르스테라이트를 사용했고, 고압상의 동정은 XRD 분석을 통해 수행하였다. 광물의 상전이를 통해 $1,200^{\circ}C$에서 시료에 가해지는 압력을 유추할 수 있었으며, ${\alpha}$-석영에서 코에사이트로의 상전이는 3.1 GPa, 석류석 구조의 $CaGeO_3$에서 페로브스카이트 구조의 $CaGeO_3$로의 상전이는 5.9 GPa, 코에사이트에서 스티쇼바이트로의 상전이는 9.2 GPa, 포르스테라이트에서 와즐리아이트로의 상전이는 13.6 GPa의 압력 확인에 이용했다. XRD 결과로 획득한 압력-부하 보정 곡선은 기존에 보고된 유사한 기기의 압력-부하 보정 곡선에 비해 동일 압력을 구현하기 위해 50톤 가량의 유압이 더 필요한 것으로 확인됐다. 이러한 차이는 시료실의 크기 및 조립세트의 압력 매체(pressure medium)와 이차앤빌 사이의 마찰력으로부터 기인한 유압 손실에 의한 것으로 생각된다. 또한 본 연구에서는 14/8 HT 조립세트에서의 시료실 내의 온도구배를 확인했다. 특히 열전대(thermocouple)의 위치 변화에 따라 시료실 높이에 평행한 방향으로 약 ${\sim}200^{\circ}C/mm$에 해당하는 온도구배가 존재한다. 본 연구로부터 구한 멀티 앤빌 프레스의 압력-부하 보정 곡선과 시료실 내의 온도구배 값은 앞으로 맨틀 내에서의 다양한 비정질 및 결정질의 지구물질에 대한 원자 구조의 변화와 그에 따른 물성 변화를 설명하는 데 적용할 수 있다.

• Computers and Concrete
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• 제26권4호
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• pp.309-316
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• 2020

The application of multi-variable adaptive regression spline (MARS) in predicting he long-term compressive strength of a concrete with various admixtures has been investigated in this study. The compressive strength of concrete specimens, which were made based on 24 different mix designs using various mineral and chemical admixtures in different curing ages have been obtained. First, The values of fly ash (FA), micro-silica (MS), water-reducing admixture (WRA), coarse and fine aggregates, cement, water, age of samples and compressive strength were defined as inputs to the model, and MARS analysis was used to model the compressive strength of concrete and to evaluate the most important parameters affecting the estimation of compressive strength of the concrete. Next, the proposed equation by the MARS method using particle swarm optimization (PSO) algorithm has been optimized to have more efficient equation from the economical point of view. The proposed model in this study predicted the compressive strength of the concrete with various admixtures with a correlation coefficient of R=0.958 rather than the measured compressive strengths within the laboratory. The final model reduced the production cost and provided compressive strength by reducing the WRA and increasing the FA and curing days, simultaneously. It was also found that due to the use of the liquid membrane-forming compounds (LMFC) for its lower cost than water spraying method (SWM) and also for the longer operating time of the LMFC having positive mechanical effects on the final concrete, the final product had lower cost and better mechanical properties.

• 자원환경지질
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• 제44권2호
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• pp.153-159
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• 2011

본 연구에서는 포괄적 역학모델을 이용하여 석유 생산 시스템의 파이프 내 가스-오일 2상유동에 대한 유동패턴을 결정하였다. 2상의 유체는 운영 인자, 기하학적 변수, 유체 물성 등에 따라 특정의 유동패턴을 나타냈다. 광범위한 기액 겉보기 속도에 대하여 시스템의 인자들을 변화시키면서 유동패턴을 비교하였다. 다양한 인자들 중 경사각과 겉보기 속도가 파이프 내 가스-오일 2상유동의 유용패턴을 결정하는데 가장 지배적인 인자로 나타났다. 파이프 직경, 유체 물성 등의 인자들은 전이 경계선 부근을 제외하면 유동패턴 변화에 제한적인 영향 만을 미쳤다. 역학모델은 실험실 평가나 신뢰성있는 상관식 이용이 불가능할 때 유동패턴을 결정할 수 있는 유용한 도구이다.

• 한국재료학회지
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• 제16권3호
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• pp.188-192
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• 2006

The microstructures and mechanical properties of continuously porous $SiC-Si_3N_4$composites fabricated by multi-pass extrusion were investigated at different Si levels added. Si-powder with different weight percentages (0%, 5%, 10%, 15%, 20%) was added to the SiC powder to make the raw mixture powders, with $6wt%Y_2O_3-2wt%Al_2O_3$ as sintering additives, carbon ($10-15{\mu}m$) as a pore-forming agent, ethylene vinyl acetate as a binder and stearic acid ($CH_3(CH_2)_{16}COOH$) as a lubricant. In the continuously porous $SiC-Si_3N_4$ composites, $Si_3N_4$ whiskers like the hairs of nostrils were frequently observed on the wall of the pores. In this study, the morphology of the $Si_3N_4$ whiskers was investigated with the silicon addition content. In the composites containing of 10 wt% Si, a large number of $Si_3N_4$ whiskers was found at the continuous pore regions. In the sample to which 15 wt% Si powder was added, maximum values of about 101 MPa bending strength and 57.5% relative density were obtained.

• 한국신재생에너지학회:학술대회논문집
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• 한국신재생에너지학회 2006년도 추계학술대회
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• pp.50-53
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• 2006

Regional geophysical surveys and geological cal studies on natural gas hydrate (NGH) in the East Sea were carried out by the Korea Institute of Geoscience and Mineral Resources (KIGAM) from 2000 to 2004. 16 piston cores, 2270 L-km of multi-channel reflection seismic (MCRS) data and 730 L-km of 3.5kHz Chirp data obtained from the southwestern part of the deep-water Ulleung Basin were analyzed in this study. In piston cores, cracks generally developed parallel to bedding suggest significant gas content. The core analyses showed high total organic carbon (TOC) content, sedimentation rate and heat flow of sediments. These are in favor of the general ion of substantial biogenic methane, which can form the NGH within the stability zone of the near seafloor sediments in the study area. The cores generally show also high residual hydrocarbon gas concentrations for the formation of natural gas hydrates The geophysical indicators of the presence of gas and/or NGH such as bottom simulating reflectors (BSRs), seismic blank Bones, pockmarks and gas seeping features were well defined on the MCRS and Chirp data.

• 한국초지조사료학회지
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• 제16권1호
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• pp.27-38
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• 1996

This study was conducted to evaluate the potential of Festulolium braunii(Festuca pratensis Huds. $\times$ Loliurn mulrijZorum Lam.)as forge sources. The experiment was arranged in a split plot design with four replications from Feb. 1995. to Jan. 1996 at Hohenheim university. Main plots consisted of three forage species, Festulolirtrn braunii(Paulita), Lolium multiJomm(Lemtla), and Secale cereale(Halo) and subplots consisted of three maturity, boot, heading, and anthesis. The growth characteristics, DM yields, nutritive value, N and energy balance were observed. The heading date of Festulolium braunii was about two days earlier than that of Loliunz mrtltiflorum, farthermore Fesrulolium braunii retained higher leaf weight ratio(LWR) than other species. Festulolium brarrnii failed to show any significant differences in grass length, number of tillers, LAI, CGR, and DM accumulation when harvested at the same stage of maturity as compare with Loliurn mulriiflorutn or Setale cerede, bur the content of CP, OMD, and mineral elements and NEL value of Festulolium braunii compare to othes were slightly increased(P<0.05), while the content of NDF, ADF, and lignin decreased(P<0.05). The yield of CP was greater for Festulolium braunii than for Lolium multfimm and yields of DOM and NEL per unit area(ha) for Festulolium braunii were greater than for other species(P<0.05). The equivalent or higher DM production and nutritive value are obtained when Festulolium braunii are cut during the period from boot to anthesis stages, therefor DM intake, preference, and N and energy balance were also higher for Festulolirtm braunii compare to for other species. It could be suggested that Lolium multrfirum would be a more suitable substitute to Festuloliron braunii without decreasing forage production and quality, but the substitutive effect of Secale cereale would be difficult because of the maor differences in growth type and period compare to Fesrulolium braunii. From above the results of this experiment it appears that Festulolium braunii have a potential to provide forage sources. but funher research is needed to ascertain their potential under the climate of Korea.

• 한국수산과학회지
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• 제21권4호
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• pp.259-268
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• 1988

광포만 집수유역에 분포된 점토광상들은 회장암질 암체에 제한되어 산출된다. 광체의 최상부에서는 로몬타이트와 메타-할로이사이트가 가장 우세하게 발달되고 철산화물이 수반되며, 하부에서는 녹니석과 할로이사이트가 우세하게 산출된다. 주점토층 아래에 놓인 일부 회장암질 암류는 열수맥을 따라 석영, 견운모, 녹니석, 황철석 및 몬모릴로나이트 등으로 실하게 변질되어 있다. 연수와 강우를 각각 $100^{\circ}C$와 $25^{\circ}C$에서 회장암질암과 반응시킨 다성분 평형 반응계산에 의해 열수변질과 풍화변질 기원의 가설들을 시험해본 결과 강우와의 반응결과가 야외에서 산출되는 점토광물군과 보다 유사함을 보인다. 이는 본역 점토광상의 주성인이 풍화변질작용임을 나타낸다.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제32권6호
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• pp.495-505
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• 2006

In this study we evaluate the effects of bFGF-BB and PDGF on in vitro proliferation, differentiation and mineralization of mesenchymal stem cells (MSCs) from rat. MSCs were prepared from the bone marrow of 6 or 7-week-old male rats with a technique previously described by Maniatopoulos et al. in 1988. Lineage differentiation to osteogenesis, chondrogenesis and adipogenesis were performed. At first, we characterized the cultured cell on passage 1, 3, 5, 7 with immunocytochemical staining using CD29, 44, 34, 45, ${\alpha}$-SMA and type I collagen. And to study the effects of bFGF and PDGF-BB on proliferation, differentiation and mineralization, we seeded the expanded cell at a density of 6 $6{\times}10^3\;cells/cm^2$ to 100-mm dish for evaluation of cell proliferation and MTT assay was carried out on day 2, 4, 7, 9. We also resuspended the cells with same density $(6{\times}10^3\;cells/cm^2)$ to 24 well plates for subculture. On the following day, the attached cells were exposed to 2.5ng/ml bFGF and/or 25ng/ml PDGF-BB daily during 5 days. The osteocalcin (OC) level was assessed and mineral contents were evaluated with alizarin red S staining on subculture day 2, 7, 14, 21. We identified the mesenchymal stem cell from the bone marrow derived cells of rat through their successful multi-differentiation and stable display of its phenotype. And bFGF and PDGF-BB showed the effect that inhibited osteoblastic differentiation and mineralization mildly in above concentration at in vitro culture. This study was supported by grant 04-2004-0120 from the Seoul National University Hospital Research Fund.

• 터널과지하공간
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• 제5권1호
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• pp.22-40
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• 1995

Thermomechanical characteristics of rocks such as thermal shock, thermal expansion, thermal cracking were experimentally investigaed using Iksan granite, Cheonan tonalite and Chung-ju dolomite to obtain the basic data for proper design and Chung-ju dolomite to obtain the basic data for proper design and stability analysis of underground structures subjected to temperature changes. The effect of thermal shock did not appear when the heating speed was under 3$^{\circ}C$/min. and there existed little difference between multi-staged cyclic heating and single-cycled heating. Thermal expansion of rocks was affected by mineral composition, crack porosity and the degree of thermal craking. In quartz-beraring multimineralic rocks such as Iksan granite and Cheonan tonalite, the thermal expansion coefficient increaseed continuously with temperature rise, but that of Chung-ju dolomite which was a monomineralic rock showed a constant value for the temperature above 250$^{\circ}C$, Chung-ju dolomite yielded the lowest critical threshold temperature(Tc) of 100$^{\circ}C$ and unstable thermal cracking was initiated above the new threshold temperature(Tc')of 300$^{\circ}C$. Above Tc' thermal cracks grew but they were not interconnected. Iksan granite showed closing of microcracks to the temperature of 100$^{\circ}C$, then expanded linearly to Tc of 200$^{\circ}C$. Above Tc, thermal cracking was initiated and progressed rapidly and almost all the grain boundaries were cracked at 600$^{\circ}C$. Cheonan tonalite also showed similar behavior to iksan granite except that Tc was 350$^{\circ}C$ and that thermal cracks propagated more rapidly. Thermal expansions calculated by Turner's equation were found to be valid in predicting the thermal expansion and cracking behavior of rocks.