• Title/Summary/Keyword: Multi-factor Test

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Prognostic Model Built on Blood-based Biomarkers in Patients with Metastatic Colorectal Cancer

  • He, Wen-Zhuo;Jiang, Chang;Yin, Chen-Xi;Guo, Gui-Fang;Rong, Ru-Ming;Qiu, Hui-Juan;Chen, Xu-Xian;Zhang, Bei;Xia, Liang-Ping
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.17
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    • pp.7327-7331
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    • 2014
  • Background: We had previously showed that the neutrophil lymphocyte ratio (NLR), ${\gamma}$-glutamyl transpeptidase (GGT) and carcinoembryonic antigen (CEA) are prognostic factors for metastatic colorectal cancer (mCRC) patients. In this study we developed a prognostic model based on these three indices. Materials and Methods: A total of 243 patients who were initially diagnosed as mCRC between 2005 and 2010 in the Sun Yat-sen University Cancer Center were studied. The endpoint was overall survival (OS). Results: NLR>3, elevated GGT and elevated CEA were confirmed as independent risk factors which could predict poor prognosis. Patients could be divided into three groups according to the number of risk factors they had. Those with two or three were defined as the high risk group, individuals with one risk factor as the modest risk group and patients without risk factor as the low risk group. The OS values for these three groups were 16.2 months (2.80~68.8), 24.2 months (4.07~79.0), and 37.2 months (12.6~87.8), respectively (p<0.001). Conclusions: We developed a simple but useful model based on NLR, GGT and CEA to provide prognostic information to clinical practice in highly selected mCRC patients. Further prospective and multi-center studies are warranted to test our model.

A study to Explore the Effect Relationship of Character and Life Goal on Happiness for Gifted Elementary Students in Science (초등과학영재학생의 인성, 생애목표와 행복감의 관계)

  • Chang, Heesun
    • Journal of Gifted/Talented Education
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    • v.26 no.1
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    • pp.161-185
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    • 2016
  • The purpose of this study was to investigate for gifted elementary students in science the feature of character, life goals and happiness, and the effect relationship on happiness based on the relationship between factors. For this, independent t-test, multi-linear regression analysis and hierarchical regression were conducted. The results from this study are as follows. First, scientifically gifted elementary students show higher level of responsibility, ethics, positive self-understanding and contribution goal, but lower in material and image goal than general students. Second, character, life goal and happiness are correlated. Third, female students rather than male students and students with consideration/service character have intrinsic goals. While, the students with higher level of consideration/service and lower level of sympathy show extrinsic goals. The higher the level of consideration/service and the lower of self-control they have the higher their happiness are. Fourth, as scientifically gifted elementary students have more consideration and relationship goal, their happiness go up. While, the more they have self-growth and material goal, the lower the happiness. Fifth, the character of scientifically gifted elementary students is the factor that explains the effect on happiness more easily than life goal, relatively. The factor of life goal mediates the consideration/service and happiness. In conclusion, I hope that this study contribute to raise the happiness of scientifically gifted elementary students, and considerate the character education and counseling program for character development.

A Study of the Factors influencing on Client's Violence in a Shelter for Teenage Runaway (청소년쉼터에서의 클라이언트 폭력에 영향을 미치는 요인)

  • Yoon, Suk Ja;Kim, Hee Jeong
    • Journal of Digital Convergence
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    • v.11 no.1
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    • pp.1-11
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    • 2013
  • This study attempt to explore how much characteristics of personal and institutional of staffs in shelter for teenage runaway influence to client's violence, and which factor of them are relative to client's violence. For this aims, we carried out a survey, survey subjects in shelter for teenage runaway participated in this research. T-test and variance analysis attempted to compare degree of violence experience of respondents by personal and institutional characteristics. According to result of analysis, age in the midst of personal characteristics is meaning difference and duty-time and type of shelter in the midst of institutional characteristics revealed meaning difference. Next, Multi-regression analysis tried to explore relative factor influencing on client's violence. The results, age in the midst of personal characteristics is relative with physical violence, duty-year in present institution is relative with etc harm. Also, duty-time per week of institutional characteristics is relative all with four type of violence. Type of shelter is relative with property harm, emotional violence and etc harm. Counseling time during duty is relative with physical violence. Above results provide basic data to find ways preventing client's violence to staffs in shelter for teenage runaway.

A Study of the Establishment of BIM Design Environment based on Virtual Desktop Infrastructure(VDI) of Cloud Computing Technology (클라우드 컴퓨팅 기술을 활용한 데스크탑 가상화 기반의 BIM 설계 환경 구축에 관한 연구)

  • Shin, Joonghwan;Lee, Kyuhyup;Kwon, Soonwook;Choi, Gyuseong;Ko, Hyunglyu
    • Korean Journal of Construction Engineering and Management
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    • v.16 no.4
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    • pp.118-128
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    • 2015
  • Recently BIM technology has been expanded for using in construction project. Due to the high-cost of BIM infrastructure development, lack of regulations, lack of process and so forth, usage of BIM has been delayed than initial expectations. In design phase, especially, collaboration based on BIM system has been a key factor for successful next generation building project. Through the analysis of current research trends about IT technologies, virtualization and BIM service, data exchange such as drawings, 3D model, object data, properties using cloud computing and virtual server system is defined as a most successful solution. The purpose of this study is to enable the cloud computing BIM server to provide several main functions such as editing models, 3D model viewing and checking, mark-up and snapshot in high-performance quality by proper design of VDI system. Concurrent client connection performance is a main technical index of VDI. Through testing of test-bed server client, developed VDI system's multi-connect control is evaluated. Performance-test result of BIM server VDI effect to development direction of cloud computing BIM service for commercialization.

A Study on the Fire Characterization of Foam block using Cone-calorimeter and FTIR (콘칼로리미터와 적외선분광계(FTIR)를 이용한 폼블럭의 연소특성에 대한 실험적 연구)

  • Han, Bong-Hoon;Seo, Dong-Ho;Kwon, Young-Hee;Min, Se-Hong
    • Fire Science and Engineering
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    • v.31 no.6
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    • pp.23-32
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    • 2017
  • Foam block, popularized as the self-interior goods, is susceptible to fire since the main material is the polyethylene flammable synthetic resin. However, it is widely used in homes, offices, and multi-use facilities. In order to understand the fire characteristics of the foam block, two kinds of foam blocks sold in the market (non-fire retardant and fire retardant) were evaluated according to standard of KS F 5660-1 (Reaction to fire test). In addition, the hazard analysis of the gas generated by the combustion of the specimen was performed using the FTIR gas analyzer. The cone calorimeter test showed that the ignition and flame combustion of both two specimens were burned as soon as the radiant heat blocking device was removed, and it was confirmed that the flame could become a rapid propagation factor during the fire. The analysis of the combustion gas through the FTIR gas analyzer showed that both the carbon dioxide and carbon monoxide classified as the common combustion gases and the acrolein, ammonia, and hydrogen cyanide causing serious damage to the human body were detected substantially. This study showed that a foam block product has high ignitionability and generates toxic gases. Hence, it is urgently required to establish the standards used for properly classifying the combustion characteristics of the material on the basis of the use conditions of a foam block product and to prepare the standards on the purpose of use.

A Study on the History Matching and Assessment of Production Performance in a Shale Gas Reservoir Considering Influenced Parameter for Productivity (생산 영향인자를 고려한 셰일가스 저류층의 이력검증 및 생산성 평가 연구)

  • Park, Kyung-Sick;Lee, Jeong-Hwan
    • Journal of the Korean Institute of Gas
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    • v.24 no.4
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    • pp.62-72
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    • 2020
  • This study presents a methodology of history matching to evaluate the productivity of shale gas reservoir with high reliability and predict future production rate in the Horn-River basin, Canada. Sensitivity analysis was performed to analyze the effect of physical properties of shale gas reservoir on productivity. Based on the results, reservoir properties were classified into 4 cases and history matching were performed considering the classified 4 cases as objective function. The blind test was conducted using additional field production data for 3 years after the history matching period. The error of gas production rate in Case 1(all reservoir parameters), Case 2(influenced parameters for productivity), Case 3(controllable parameters), and Case 4(uncontrollable parameters) were 7.67%, 7.13%, 17.54%, and 10.04%, respectively. This means that it seems to be effective to consider all reservoir parameters in early period for 4 years but Case 2 which considered influenced parameters for productivity shows the highest reliability in predicting future production. The estimated ultimate recovery (EUR) of production well predicted using the Case 2 model was estimated to be 17.24 Bcf by December 2030 and the recovery factor compared to original gas in place (OGIP) was 32.2%.

The Case Study on the Design, Construction, Quality Control of Deep Cement Mixing Method (심층혼합처리공법(DCM)의 설계, 시공 및 품질관리 사례 연구)

  • Kim, Byung-Il;Park, Eon-Sang;Han, Sang-Jae
    • Journal of the Korean Geosynthetics Society
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    • v.20 no.4
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    • pp.19-32
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    • 2021
  • In this study, evaluation and consideration of domestic/overseas design, construction, and quality control performed by the authors on the deep cement mixing method were performed, and improvements for the development of the DCM method were suggested in the future. As a result of this study, it was found that the cross-sectional area correction for strength is required during the laboratory test of mix proportion, and caution is required because the extrapolation method may lead to different results from the actual one. Applicable design methods should be selected in consideration of both the improvement ratio and the type of improvement during design, and it was confirmed that the allowable compressive strength to which the safety factor was applied refers to the standard value for stability review and not the design parameters. In the case of the stress concentration ratio, rather than applying a conventional value, it was possible to perform economical design by calculating the experimental and theoretical stress concentration ratio reflecting the design conditions. In the case where pre-boring is expected during construction, if the increased water content is not large compared to the original, there were cases where a major problem did not occur even if the result that did not consider the increase in water content was used. In addition, it was confirmed that when the ratio of the top treatment length to the improved length is high, a small amount of design cement contents per unit length can be injected during construction. In the case of quality control, it was evaluated that D/4~2D/4 for single-axis and D/4 point for multi-axis were optimal for coring of grouting mixtures. As an item for quality control, it is judged that the standard that considers the TCR along with the unconfined compressive strength of grouting mixtures is more suitable for the domestic situation.

The Mediating Effects of Depression on Loneliness and Suicidal Ideation in Elderly Living Alone with Diabetes Mellitus: A Secondary Data Analysis (독거 당뇨병 노인의 외로움이 자살사고에 미치는 영향에 대한 우울의 매개효과 검증: 2차 자료 분석)

  • Moonhee Gang;Yujin Ahn
    • Journal of Industrial Convergence
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    • v.21 no.5
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    • pp.51-58
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    • 2023
  • The purpose of this study is to analyze suicidal ideation of elderly people with diabetes living alone and to investigate the relationship between suicidal ideation, loneliness, and depression. This study was conducted through secondary data analysis using total survey data for the elderly living alone in O province. The subjects of this study were 466 elderly people who were diagnosed with diabetes among the elderly living alone. The data of this study were analyzed using descriptive statistics, t-test, Pearson's correlation coefficients, multi-linear regression analysis, and the three-step mediating effect verification procedure of Baron & Kenny using the SPSS 26.0 program. The average loneliness score and average depression score of the subjects were 4.52±3.30 and 4.88±4.03, respectively, and 27.3% of the subjects said they had a suicidal ideation. The subject's loneliness (β=.20, p=.005) and depression (β=.30, p<.001) was found to be a significant factor in predicting suicide ideation. In addition, depression was found to be partially mediated in the relationship between loneliness and suicidal ideation. Through the results of this study, loneliness and depression were found to be important factors related to suicidal ideation in the elderly with diabetes living alone. In addition, in order to improve suicidal ideation in the elderly with diabetes living alone, intervention to lower the level of loneliness and depression is necessary.

Predictive Factors of Health promotion behaviors of Industrial Shift Workers (산업장 교대근무 근로자의 건강증진행위 예측요인)

  • Kim, Young-Mi
    • Korean Journal of Occupational Health Nursing
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    • v.11 no.1
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    • pp.13-30
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    • 2002
  • Industrial shift workers feels suffer mental stresses which are caused by unfamiliar day sleep, noisy environment, sleeping disorder by bright light, unusual contacts with family, difficulty in meeting with friends or having formal social meetings and other social limitations such as the use of transportation. Such stresses influence health of the workers negatively. Thus the health promotion policy for shift workers should be made considering the workers' ways of living and shift work specially. This study attempted to provide basic information for development of the health promotion program for industrial shift workers by examining predictive factors influencing health promotion behaviors of those workers. In designing the study, three power generation plants located in Pusan and south Kyungsang province were randomly selected and therefrom 280 workers at central control, boiler and turbine rooms and environmental chemistry parts whose processes require shift works were sampled as subjects of the study. Data were collected two times from September 17 to October 8, 1999 using questionnaires with helps of safety and health managers of the plants. The questionnaires were distributed through mails or direct visits. Means for the study included the measurement tool of health promotion behavior provided by Park(1995), the tool of self-efficacy measurement by Suh(1995), the tool of internal locus of control measurement by Oh(1987), the measurement tool of perceived health state by Park(1995) and the tool of social support measurement by Paek(1995). The collected data were analyzed using SPSS program. Controlling factors of the subjects were evaluated in terms of frequency and percentage ratio Perceived factors and health promotion behaviors of the subjects were done so in terms of mean and standard deviation, and average mark and standard deviation, respectively. Relations between controlling and perceived factors were analyzed using t-test and ANOVA and those between perceived factors and the performance of health promotion behaviors, using Pearson's Correlation Coefficient. The performance of health promotion behaviors was tested using t-test, ANOVA and post multi-comparison (Scheffe test). Predictive factors of health promotion behavior were examined through the Stepwise Multiple Regression Analysis. Results of the study are summarized as follows. 1. The performance of health promotion behaviors by the subjects was evaluated as having the value of mean, $161.27{\pm}26.73$ points(min.:60, max.:240) and average mark, $2.68{\pm}0.44$ points(min.:1, max.:4). When the performance was analyzed according to related aspects, it showed the highest level in harmonious relation with average mark, $3.15{\pm}.56$ points, followed by hygienic life($3.03{\pm}.55$), self-realization ($2.84{\pm}.55$), emotional support($2.73{\pm}.61$), regular meals($2.71{\pm}.76$), self-control($2.62{\pm}.63$), health diet($2.62{\pm}.56$), rest and sleep($2.60{\pm}.59$), exercise and activity($2.53{\pm}.57$), diet control($2.52{\pm}.56$) and special health management($2.06{\pm}.65$). 2. In relations between perceived factors of the subjects(self-efficacy, internal locus of control, perceived health state) and the performance of health promotion behaviors, the performance was found having significantly pure relations with self-efficacy (r=.524, P=.000), internal locus of control (r=.225, P=.000) and perceived health state(r=.244, P=.000). The higher each evaluated point of the three factors was, the higher the performance was in level. 3. When relations between the controlling factors(demography-based social, health-related, job-related and human relations characteristics) and the performance of health promotion behaviors were analyzed, the performance showed significant differences according to marital status (t=2.09, P= .03), religion(F=3.93, P= .00) and participation in religious activities (F=8.10, P= .00) out of demography-based characteristics, medical examination results (F=7.20, P= .00) and methods of the collection of health knowledge and information(F=3.41, P= .01) and methods of desired health education(F=3.41, P= .01) out of health-related characteristics, detrimental factors perception(F=4.49, P= .01) and job satisfaction(F=8.41, P= .00) out of job-related characteristics and social support(F=14.69, P= .00) out of human relations characteristics. 4. The factor which is a variable predicting best the performance of health promotion behaviors by the subjects was the self-efficacy accounting for 27.4% of the prediction, followed by participation in religious activities, social support, job satisfaction, received health state and internal locus of control in order all of which totally account for 41.0%. In conclusion, the predictive factor which most influence the performance of health promotion behaviors by shift workers was self-efficacy. To promote the sense, therefore, it is necessary to develop the nursing intervention program considering predictive factors as variables identified in this study. Further industrial nurses should play their roles actively to help shift workers increase their capability of self-management of health.

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Statistical Analyses of Long-Term Water Quality Variation in the Geumgang-Reservoir: Focused on the TP Load by Migrating Birds Excrement (금강호의 장기 수질 변화요인 분석: 철새배설물에 의한 TP부하의 중요성)

  • Jeong, Yong-Hoon;Kim, Hyun-Soo;Yang, Jae-Sam
    • Journal of the Korean Society for Marine Environment & Energy
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    • v.13 no.4
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    • pp.223-233
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    • 2010
  • Spatio-temporal variations of long-term water qualities (COD, SS, $Chl-{\alpha}$, N-related nutrients (TN, TDN, $NO_3^-$, $NH_4^+$), P-related nutrients (TP, TDP, $PO_4^{3-}$)) at two stations (St. SD, St. GG) in the Geumgang Reservoir were investigated from August 2001 to July 2008. Statistical methods such as t-test, factor analysis, and multi-regression analysis were applied to the water quality data in the reservoir as well as mass balances on TP. From the temporal comparisons of the water qualities between 2002 and 2007, average concentrations of $NH_4^+$, $PO_4^{3-}$, and TDP gradually decreased down by 60%, 24%, 52% in 2007. However, those of TP and $Chl-{\alpha}$ increased to 99% and 423% during the period. From the spatial comparisons between the two stations, St. GG showed higher concentrations for all of the N- and P-related nutrients than in St. SD, while opposite result for the $Chl-{\alpha}$. The factor analysis showed that "the seasonal variations of N- and P-related nutrients" were the two dominant factors occupying 49% of total variances of water qualities. Based on this result, multi-regression analysis executed for the two most influential parameters (TP and $Chl-{\alpha}$) focusing on the seasonal variations of these parameters: SS and $Chl-{\alpha}$ has contributed decisively to the concentrations of TP during the wet and dry season, respectively. On the other hand, COD and TP has been important for the $Chl-{\alpha}$ during the wet and dry season, respectively. From the established mass balances of TP loadings in the Geumgang Reservoir, Other Sources (60%) occupied the greatest contribution and Fluvial Input (38%) and Sediment (1%) during the wet season. However, both Fluvial Water (48%) and Other Sources (47%) supplied comparable amount of inputs and Sediment (5%) showed significantly increased input during the dry seasons. Recently especially during the dry winter seasons, migrating bird's excretion was estimated to contribute up to 8% of total TP input and 21% of Other Sources.