• Environmental Analysis Health and Toxicology
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• v.31
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• pp.16.1-16.9
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• 2016

Objectives Banha-sasim-tang (BST), which consists of seven different herbs, is one of the most popular herbal formulae for treating gastrointestinal disorders in Eastern Asia. The commonly used herbal medicine is often co-administered with other therapeutic drugs, which raises the possibility of herb-drug interactions and may modify the clinical safety profile of therapeutic drugs. Methods We investigated the potential herb-drug interactions between BST extract and midazolam (MDZ) in mice. The area under the plasma concentration-time curve (AUC) of MDZ and 1'-hydroxymidazolam (1'-OH-MDZ) was evaluated for both oral and intraperitoneal administration of MDZ, following oral administration of BST (0.5 and 1 g/kg). Results It was found that the AUC of MDZ and 1'-OH-MDZ was lower in case of oral administration of MDZ. Administration of BST extract was not associated with hepatic cytochrome P450 activity. BST extract induced a strong reduction in pH and it has been reported that oral mucosal absorption of MDZ is lower at low pH. The decreased absorption rate of MDZ might be caused by the ingredients of BST and may not be related to other factors such as increased excretion of MDZ by P-glycoprotein. Conclusions The altered pharmacokinetics of midazolam caused by co-administration with BST in vivo could be attributed to a decrease in pH and subsequent reduction of MDZ absorption rate.

• Smart Structures and Systems
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• v.11 no.3
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• pp.261-282
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• 2013

Structural health monitoring (SHM) is an application area of Wireless Sensor Networks (WSNs) which usually needs high data communication rate to transfer a large amount of monitoring data. Traditional sink node can only process data from one communication channel at the same time because of the single radio chip structure. The sink node constitutes a bottleneck for constructing a high data rate SHM application giving rise to a long data transfer time. Multi-channel communication has been proved to be an efficient method to improve the data throughput by enabling parallel transmissions among different frequency channels. This paper proposes an 8-radio integrated sink node design method based on Field Programmable Gate Array (FPGA) and the time synchronization mechanism for the multi-channel network based on the proposed sink node. Three experiments have been performed to evaluate the data transfer ability of the developed multi-radio sink node and the performance of the time synchronization mechanism. A high data throughput of 1020Kbps of the developed sink node has been proved by experiments using IEEE.805.15.4.

• Journal of the Korean Society of Systems Engineering
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• v.12 no.1
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• pp.73-87
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• 2016

Combining power generation and water production by desalination is economically advantageous. Most desalination projects use fossil fuels as an energy source, and thus contribute to increased levels of greenhouse gases. Environmental concerns have spurred researchers to find new sources of energy for desalination plants. The coupling of nuclear power production with desalination is one of the best options to achieve growth with lower environmental impact. In this paper, we will per-form a sensitivity study of coupling nuclear power to various combinations of desalination technology: {1} thermal (MSF [Multi-Stage Flashing], MED [Multi-Effect Distillation], and MED-TVC [Multi-Effect Distillation with Thermal Vapour Compression]); {2} membrane RO [Reverse Osmosis]; and {3} hybrid (MSF-RO [Multi-Stage Flashing & Reverse Osmosis] and MED-RO [Multi-Effect Distillation & Reverse Osmosis]). The Korean designed reactor plant, the APR1400 will be modeled as the energy production facility. The economical evaluation will then be executed using the computer program DEEP (Desalination Economic Evaluation Program) as developed by the IAEA. The program has capabilities to model several types of nuclear and fossil power plants, nuclear and fossil heat sources, and thermal distillation and membrane desalination technologies. The output of DEEP includes levelized water and power costs, breakdowns of cost components, energy consumption, and net saleable power for any selected option. In this study, we will examine the APR1400 coupled with a desalination power plant in the Kingdom of Saudi Arabia (KSA) as a prototypical example. The KSA currently has approximately 20% of the installed worldwide capacity for seawater desalination. Utilities such as power and water are constructed and run by the government. Per state practice, economic evaluation for these utilities do not consider or apply interest or carrying cost. Therefore, in this paper the evaluation results will be based on two scenarios. The first one assumes the water utility is under direct government control and in this case the interest and discount rate will be set to zero. The second scenario will assume that the water utility is controlled by a private enterprise and in this case we will consider different values of interest and discount rates (4%, 8%, & 12%).

• Journal of Korea Soil Environment Society
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• v.2 no.3
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• pp.59-67
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• 1997

To investigate the effects of organic matter and soil depth on soil water flow in a multi-layered soil, the saturated hydraulic conductivities(Ksat) were measured from the single- and multi-layered soil columns, that the soils were mixed with the oven-dried cow manure compost(CMC) at 4 different ratios such as 0, 2, 4, and 6% on a weight basis. The measured hydraulic conductivities(Ksat) were compared with theoretical hydraulic conductivity (Keff calculated by Jury's equation of effective hydraulic conductivity. In the single layered soil column saturated hydraulic conductivities(Ksat) were significantly decreased with increasing the application rate of compost. In the multi-layered the soil columns Ksat was also decreased with increasing rate of compost and soil depth. Calculated Keff showed the similar results of Ksat as obtained from the measured Ksat, whereas steadily increased with increasing soil depth. Therefore, modification of Jury's equation should be required to adapt theoretical Keff for Held application.

• Journal of Environmental Science International
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• v.22 no.7
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• pp.863-871
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• 2013

Dielectric discharges are an emerging technique in environmental pollutant degradation, which that are characterized by the production of hydroxyl radicals as the primary degradation species. For practical application of the plasma reactor, reactor that can handle large amounts of water are needed. Plasma research to date has focused on small-scale water treatment. This study was carried out basic study for scale-up of a single DBD (dielectric barrier discharge) plasma reactor. The degradation of N, N-Dimethyl-4-nitrosoaniline (RNO, indicator of the generation of OH radical) was used as a performance indicator of multi-plasma reactor. The experiments is divided into two parts: design parameters [effect of distance of single plasma module (1~14 cm), arrangement of ground electrode (single and multi), rector number (1~5) and power number (1~5)]; operation parameter [effect of applied voltage (60~220 V), air flow rate (1~5 L/min), electric conductivity of solution ($1.4{\mu}S/cm$, deionized water)~18.8 mS/cm (addition of NaCl 10 g/L) and pH (5~9)]. Considering the electric stability of the plasma reactor, optimum spacing between the single plasma module was 2 cm. Multi discharge electrodes - single ground electrode array was selected. Combination of power 3-plasma module 5 was the optimal combination for maximum RNO degradation. The optimum 1st voltage and air flow rate for RNO degradation were 180 V and 4 L/min, respectively. The pH and conductivity of the solution was not influencing the RNO degradation.

• Journal of the Ergonomics Society of Korea
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• v.26 no.2
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• pp.157-165
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• 2007

The Work-Related Musculoskeletal Disorders (WMSDs) can be occurred by various factors such as repetition, forceful exertions and awkward postures. Especially, occurrences of the WMSDs on the waist and lower limb are reported in workplaces, demanded standing postures for a long time, in service and manufacturing industry. The static and standing postures without movement for a long time increase work loads to the lower limb and the waist. Accordingly, anti-fatigue mat or anti-fatigue insole is used as a preventing device of the WMSDs. However anti-fatigue mats are limited in space and movement. In this study, multi-elastic insoles are designed and shown the effects of the workload reduction for a long time under the standing work. The foot pressures and EMG (Electromyography) are measured at 0 hour and after 2 hours by 6 health students in their twenties. The 6 prototype insoles are designed with three elastic (Low, Medium and High). These insoles are compared with no insole (insole type 7) as control group. The EMG measurement was conducted to waist (erector spinae muscle), thigh (vastus lateralis muscle) and calf (gastrocnemius muscle). The foot pressure is analyzed by mean pressure value and the EMG analysis is investigated through MF (Median Frequency), MPF (Mean Power Frequency) and ZCR (Zero Crossing Rate). The results of the foot pressure show that the multi-elastic insoles had smaller foot pressure value than that of no-insole. Moreover, Insole 2 and Insole 3 have the smallest increasing rate in foot pressure. The EMG results show that the multi-elastic insoles had smaller EMG shift value than that of no-insole in 2 hour, and then shift value shows the smallest value in Insole 2. Therefore, this study presents that the multi-elastic insoles have reducing effects of the work load for a long time standing work in both side of foot pressure and EMG.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.32 no.1A
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• pp.51-56
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• 2007

Unitary matrix modulation (UMM) is investigated in multiple antennas system that is called unitary space-time modulation (USTM). When we consider only diagonal components of UMM with splitting over the coherence bandwidth, the system can obtain frequency diversity in a single antenna system. In Rayleigh fading channel, we compared USTM/OFDM with 2Tx-antenna with UMM-S/OFDM with 1Tx-antenna, conventional multi-level OFDM and UMM-S/OFDM with changing bit rate per Hz. Also, we analyzed SNR for between multi-level modulation STBC/OFDM and multi-level modulation UMM-S/OFDM with changing transmission rate. When it was adaptive multi-level modulation to improve SNR, we did the UMM-S/OFDM system performance analysis of N-ary PSK and M-ary QAM.

• International Journal of Computer Science & Network Security
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• v.23 no.7
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• pp.1-8
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• 2023

An Orthogonal Frequency Division Multiplexing (OFDM) based wireless communication system has drawn wide attention for its high transmission rate and high spectrum efficiency in not only radio but also Underwater Acoustic (UWA) applications. Because of the narrow sub-carrier spacing of OFDM, orthogonality between sub-carriers is easily affected by Doppler effect caused by the movement of transmitter or receiver. Previously, Doppler compensation signal processing algorithm for Desired propagation path was proposed. However, other Doppler shifts caused by delayed Undesired signal arriving from different directions cannot be perfectly compensated. Then Receiver Bit Error Rate (BER) is degraded by Inter-Carrier-Interference (ICI) caused in the case of Multi-path Doppler channel. To mitigate the ICI effect, a modified Delay and Doppler Profiler (mDDP), which estimates not only attenuation, relative delay and Doppler shift but also sampling clock shift of each multi-path component, is proposed. Based on the outputs of mDDP, an ICI canceling multi-tap equalizer is also proposed. Computer simulated performances of one-tap equalizer with the conventional Time domain linear interpolated Channel Transfer Function (CTF) estimator, multi-tap equalizer based on mDDP are compared. According to the simulation results, BER improvement has been observed. Especially, in the condition of 16QAM modulation, transmitting vessel speed of 6m/s, two-path multipath channel with direct path and ocean surface reflection path; more than one order of magnitude BER reduction has been observed at CNR=30dB.

• Proceedings of the IEEK Conference
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• 2000.09a
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• pp.951-954
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• 2000

In this paper, we present a multi-code parallel combinatory CDMA system using bi-orthogonal modulation to reduce envelope variation and improve bit error. .rate (BER) performance. In general, the dynamic range of the amplitude of the transmit signal is very large in the case of conventional multi-code CDMA systems, resulting in severe nonlinear distortion due to high power amplifier and thus significant BER performance degradation. The proposed system exhibits reduction of peak-to-average power ratio (PAPR) of the transmit signal amplitudes and significant performance improvement. We verify the performance of the proposed system by computer simulations under AWGN channel and flat fading channel.

• Journal of Korean Society for Quality Management
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• v.36 no.2
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• pp.9-19
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• 2008

Spare part problem of MIME (Multi Indenture Multi Echelon) system under availability constraint has been studied for several decades. In most of existing studies, it was very difficult to obtain the optimal numbers of spare parts and some approximate methods were proposed under many restrictions. In this paper, we consider a simulation to estimate the total cost rate and system availability and a genetic algorithm to obtain the optimal numbers of spare parts. Some numerical examples are also studied.