• Asian Pacific Journal of Cancer Prevention
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• v.13 no.10
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• pp.4999-5002
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• 2012

Introduction: There is epidemiological evidence indicating that the metabolic syndrome increases the risk of colorectal cancer. Since there is little information about this issue in Iran, the present study was conducted to evaluate prevalence of metabolic syndrome and its components in patients with colorectal cancer. Material and Methods: This cross-sectional survey involved 200 patients with a new diagnosis of colorectal cancer. Demographic information of patients was collected through the interview with them. Components of metabolic syndrome including fasting glucose serum, triglyceride, high density lipoprotein, blood pressure and waist circumference were measured for all of the patients. Results: A total of 72 colorectal cancer patients (36%) met metabolic syndrome criteria with rates of 76% for women and 24% for men. BMI in metabolic syndrome patients was higher than other colorectal cancer patients. Disease history including hypertension, diabetes and cardiovascular disease was most frequent in metabolic syndrome patients. Pathological characteristics of colorectal cancer were not significantly associated with the disease. Conclusion: The findings of present study indicated that the prevalence of metabolic syndrome in CRC patients is relatively high. Therefore, further analytical and multi centric studies are needed to better understand the role of metabolic syndrome in development of CRC in Iran. If this association is confirmed in future studies, metabolic syndrome patients should be considered in CRC screening programs.

• Journal of Drive and Control
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• v.14 no.2
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• pp.23-29
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• 2017

In this study, a flexible multi-body dynamic simulation model of a knuckle boom crane is developed to evaluate the stress of spindle and rack gears under dynamic working conditions. It is difficult to predict potential critical damage to a knuckle boom crane if only the static condition is considered during the development process. To solve this issue, a severe working scenario (high speed with heavy load) was simulated as a boundary condition for testing the integrity of the dynamic simulation model. The crane gear model is defined as a flexible body so contact analysis was performed. The functional motion of a knuckle boom crane is generated by applying forces at each end of the rack gear, which was converted from hydraulic pressure measured for the experiment. The bending and contact stress of gears are theoretically calculated to validate the simulation model. In the simulation, the maximum stress of spindle and rack gears are observed when the crane abruptly stops. Peak impact force is produced at the contact interface between pinion and rack gears due to the inertia force of the boom. However, the maximum stress (bending/contact) of spindle and rack are under the yield stress, which is safe from damage. By using the developed simulation model, the experiment process is expected to be minimized.

• The Journal of Information Systems
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• v.12 no.2
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• pp.57-72
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• 2003

The purpose of this paper is to propose the modeling of multiagent based SCM and implement the prototype in the Internet environment. SCM process follows the supply chain operations reference (SCOR) model which has been suggested by Supply Chain Counsil. SCOR model has been positioned to become the industry standard for describing and improving operational process in SCM. Five basic processes, plan, source, matte, deliver and return are defined in the SCOR model, through which a company establishes its supply chain competitive objectives. A supply chain is a world wide network of suppliers, factories, warehouses, distribution centers and retailers through which raw materials are acquired, transformed or manufactured and delivered to customers by autonomous or semiautonomous process. With the pressure from the higher standard of customer compliance, a frequent model change, product complexity and globalization, the combination of supply chain process with an advanced infrastructure in terms of multiagent systems have been highly required. Since SCM is fundamentally concerned with coherence among multiple decision makers, a multiagent framework based on explicit communication between constituent agents such as suppliers, manufacturers, and distributors is a natural choice. Multiagent framework is defined to perform different activities within a supply chain. Dynamic and changing functions of supply chain can be dealt with multi-agent by cooperating with other agents. In the areas of inventory management, remote diagnostics, communications with field workers, order fulfillment including tracking and monitoring, stock visibility, real-time shop floor data collection, asset tracking and warehousing, customer-centric supply chain can be applied and implemented utilizing multiagent. In this paper, for the order processing event between the buyer and seller relationship, multiagent were defined corresponding to the SCOR process. A prototype system was developed and implemented on the actual TCP/IP environment for the purchase order processing event. The implementation result assures that multiagent based SCM enhances the speed, visibility, proactiveness and responsiveness of activities in the supply chain.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.30 no.6 s.249
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• pp.553-559
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• 2006

Most diesel injector, which is currently used in high-pressure common rail fuel injection system of diesel engine, is driven by the solenoid coil energy for its needle movement. The main disadvantage of this solenoid-driven injector is a high power consumption, high power loss through solenoid coil and relatively fixed needle response's problem. In this study, a prototype piezo-driven injector, as a new injector mechanism driven by piezoelectric energy based on the concept of inverse piezo-electric effect, has been designed and fabricated to know the effect of piezo-driven injection processes on the diesel spray structure and internal nozzle flow. Firstly we investigated the spray characteristics in a constant volume chamber pressurized by nitrogen gas using the back diffusion light illumination method for high-speed temporal photography and also analyzed the inside nozzle flow by a fully transient simulation with cavitation model using VOF(volume of fraction) method. The numerical calculation has been performed to simulate the cavitating flow of 3-dimensional real size single hole nozzle along the injection duration. Results were compared between a conventional solenoid-driven injector and piezo-driven injector, both equipped with the same micro-sac multi-hole injection nozzle. The experimental results show that the piezo-driven injector has short injection delay and a faster spray development and produces higher injection velocity than the solenoid-driven injector. And the predicted simulation results with the degree of cavitation's generation inside nozzle for faster needle response In a piezo-driven injector were reflected to spray development in agreement with the experimental spray images.

• Journal of Advanced Marine Engineering and Technology
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• v.30 no.5
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• pp.572-579
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• 2006

Accurate heat release analysis based on the cylinder pressure trace is important for evaluating combustion process of diesel engines. However, traditional single-zone heat release models (SZM) have significant limitations due mainly to their simplified assumptions of uniform charge and homogeneity while neglecting local temperature distribution inside cylinder during combustion process. In this study, a heat release analysis based on single-zone model has been evaluated by comparison with computational simulation result using Fire-code, which is based on multidimensional model (MDM). The limitations of the single-zone assumption have been estimated, To overcome these limitations, an improved model that includes the effects of spatial non-uniformity has been applied. From this improved single-zone heat release model (Improved-SZM), two effective values of specific heat ratios, denoted by ${\gamma}_V$ and ${\gamma}_H$ in this study, have been introduced. These values are formulated as the function of charge temperature changing rate and overall equivalence ratio. Also, it is applied that each equation of ${\gamma}_V$ and ${\gamma}_H$ has respectively different slopes according to several meaningful periods during combustion progress. The heat release analysis results based on improved single-zone model gives a good agreement with FIRE-code results over the whole range of operating conditions of target engine, Hyundai HiMSEN H21/32.

• Proceedings of the Korean Vacuum Society Conference
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• 2014.02a
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• pp.407-407
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• 2014

Nanotechnology, especially vertically grown silicon nanowires, has gotten great attentions in biology due to characteristics of one dimensional nanostructure; controllable synthetic structure such as lengths, diameters, densities. Silicon nanowires are promising materials as nanoelectrodes due to their highly complementary metal-oxide-semiconductor (CMOS) - and bio-compatibility. Silicon nanowires are so intoxicated that are effective for bio molecular delivery and electrical stimulation. Vertical nanowires with integrated Au tips were fabricated for electrical intracellular interfacing with PC-12 cells. We have made synthesized two types of nanowire devices; one is multi-nanowires electrode for bio molecular sensing and electrical stimulation, and the other is single-nanowires electrode respectively. Here, we demonstrate that differentiation of Nerve Growth Factor (NGF) treated PC-12 cells can be promoted depending on different magnitudes of electrical stimulation and density of Si NWs. It was fabricated by both bottom-up and top-down approaches using low pressure chemical vapor deposition (LPCVD) with high vacuuming environment to electrically stimulate PC-12 cells. The effects of electrical stimulation with NGF on the morphological differentiation are observed by Scanning Electron Microscopy (SEM), and it induces neural outgrowth. Moreover, the cell cytosol can be dyed selectively depending on the degree of differentiation along with fluorescence microscopy measurement. Vertically grown silicon nanowires have further expected advantages in case of single nanowire fabrication, and will be able to expand its characteristics to diverse applications.

• Korean Journal of Materials Research
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• v.8 no.11
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• pp.987-992
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• 1998

Titanium aluminide intermetallic compound was formed from high purity elemental Ti and A1 foils by selfpropagating, high-temperature synthesis(SHS1 in hot press. Formation of $TiAl_3$ intermetallics at the interface between Ti and Al foil was observed to be controlled by temperature, pressure and heating rate. Especially, the heating rate is the most important role to form intermetallic compound by SHS reaction. According to DTA experiment, the SHS reactions appeared at two different temperatures below and above the melting point of Al. It was also observed that both SHS reaction temperatures increased with increasing the heating rate. After the SHS reaction of alternatively layered 10 Ti and 9 A1 foils at the heating rate of $20^{\circ}C$/min, the $700\mu\textrm{m}$ thick titanium aluminide sheet was formed by heat treatment at $810^{\circ}C$ for 4hours.

• Journal of the Korean Applied Science and Technology
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• v.17 no.4
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• pp.248-256
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• 2000

We investigated the property of formation of mono-vesicle(designated nano-some) with using of the combined co-emulsifiers and phospholipid. Nano-some was prepared with hydrogenated lecithin(HL) and diethanolamine cetyl phosphate(DEA-CP) by swelling reaction. Kojic acid and kojic dipalmitate could be made stabilization by nano-some system using microfluidizer(MF). Nano-some has a good affinity to skin by means of this system. The composition was compounded by 2% of hydrogenated lecithin (phosphatidyl choline contained with 75%, 0.5% of DEA-CP and 0.5% of diglyceryl dioleate (DGDO). To make nano-some, several conditions of MF have to be considered as follows. The optimum pH was 6.0. The pressure was 10,000psi and passage temperature was at $306^{\circ}C$. The nano-some base was passed to homogenize continually 3 times through MF. The Particle size distributions of the vesicles were with in $57{\sim}75.7nm$(mean 66nm) by measuring the Zetasizer-3000. Zeta potential of vesicles with 3 times passage through MF was -24.8mV. Formations for nano-some vesicle certificated photograph by scanning electric magnification (SEM). Stability of nano-some was very good for 6months. The turbidity was very good transparency compared nano-some with liposome. It was formed the mono vesicle in the opposite direction to be formed the multi-lamellar vesicle of liposome.

• Archives of Plastic Surgery
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• v.36 no.1
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• pp.80-83
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• 2009

Purpose: Isolated hypoglossal nerve palsy is a rare manifestation of various underlying disease. This article presents a rare complication of general anesthesia associated with an surgical procedure on a case of zygomatic fracture. Methods: An 18-year-old female patient was referred to our department by painful swelling on her left zygomatic area after the traffic accident. Left zygomatic complex fracture was identified on the simple x-ray and facial bone CT scan, and the fracture was treated with open reduction and internal fixation under general anesthesia. On the first postoperative day, she complained of difficulty in swallowing solid food, dysarthria and deviated tongue to her right side. There was no abnormal findings on the neurological examination, brain MRI and routine chemistry. She was diagnosed with transient hypoglossal nerve palsy and dexamethasone with multi-vitamins was administrated intravenously for 5 days. Results: The symptoms were completely resolved by the ninth postoperative day and the patient was discharged without any other complications. Conclusion: The hypoglossal(cranial nerve XII)nerve supplies motor innervation to all of the ipsilateral extrinsic and intrinsic tongue muscles. The hypoglossal nerve damage may caused by the compression between the airway and the hyoid bone during the endotracheal intubation, and direct trauma due to excessive pressure or neck extension. We described a rare case of unintended injury to hypoglossal nerve and care must be taken not to cause the hypoglossal nerve damage especially in facial plastic surgery with excessive neck extension under general anesthesia.

• The Journal of Engineering Geology
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• v.6 no.2
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• pp.59-64
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• 1996

Acoustic Emission(AE) signals are emitted by a sudden release of strain energy associated with material damage. A multi-channels of LeCroy system and piezoelectric pressure transducers are employed for AE measurement to investigate the roles of AE in the propagation of macro cracks as well as the characteris-tics of AE wave in occurrence, amplitude and dominant frequency with changes in macro loading modes. Deduced crack opening volume of micro cracks varied widely and implies that AE events could be caused by crystal dislocations on a small scale and grain boundary movements on a large scale. Amplitude of first arrival AE wave emitted during mode I test was approximately 3 times higher than those from mixed mode test, while the number of AE count in mode I test was only 25% of mixed mode. It may imply that the total energy required for generation of a given fracture surface is similar regardless in change of macroloading modes.