• Journal of the Korea Academia-Industrial cooperation Society
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• v.21 no.10
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• pp.137-143
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• 2020

To ensure safety of raw materials for military foods, hazard assessment and monitoring of residual pesticides was conducted on agricultural products consumed by 9 companies based in Gyeongin and Gangwon. Residual pesticides were analyzed for 142 different products, by applying the multi-species pesticide polycomponent analysis method. Of the 36 samples analyzed, residual pesticides were detected in 7 samples, representing a detection rate of 19.4%. One particular pesticide residue was detected in peanuts, green onions, and red pepper powder, and 20 types of pesticide residues were detected in red pepper powder used in combat foods. However, all residues were found to be below the permissible level. Moreover, the hazard assessment results for Cypermethrin, Tebuconazole and EPN showed the highest concentration among the residual pesticides detected. Since the estimated intake was less than 100% as compared to the ingestion limit, it was considered to be safe. I have suggested the edit as per my understanding. Please review for accuracy, and revise appropriately if required. This is the first pesticide Risk Assessment study encompassing military requirements. Considering the results, we expect further application research, including research on reducing hazardous materials.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.17 no.2
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• pp.649-656
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• 2016

This study was a retrospective examination to identify the association of postoperative delirium of the prognosis on following femur fracture surgery in elderly patients. Data was collected from the medical records of elderly patients (aged 65 years or older), who underwent femur fracture surgery from July 2010 to January 2014, following on 3-years in one university hospital. A total of 68 patients were involved. There were 31 cases (45.6%) with delirium and 37 cases (54.4%) without delirium. The participant's average age was 80.8 (patients with delirium), and 81.8 (delirium without patients) years of age, respectively, and most of them were female. There was no significant difference between the two groups. Taking five or more medications, serum creatinine level, and the total medical costs were significantly different in the delirium group and non-delirium group. In addition, the proportional hazard model of Cox to determine the predictors for the major clinical outcome occurring after surgery revealed delirium, five or more multi-drug use, and an experience of transfusion to be significant predictors. In conclusion, postoperative delirium in the elderly undergoing femur fracture surgery can have a negative clinical outcome in patients and caregivers. Therefore, a preoperative evaluation and management of the risk factors will be necessary.

• Journal of the Korean Society of Hazard Mitigation
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• v.11 no.3
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• pp.151-156
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• 2011

Previously most of flood prevention efforts have been made for relatively large watersheds near to channel flow. However, as economical development and the expansion of leisure areas to mountainous region, human casualty by flash flood occurs frequently, requiring additional prevention activity. Therefore, to reduce the damage of human lives and property by flash flood, we develop an assessment method for flash flood occurrence for mountainous areas considering various factors involving it. PROMETHEE(Preference Ranking Organization METHod for Enrichment Evaluations) which is one of the MCDM(Multi-Criteria Decision Making) was adopted to assess the contribution of each factor to the risk of the flash flood in the mountainous area. The main evaluation criteria are classified into three categories, namely, the regional and rainfall characteristics, and geographical features. Also, the Entropy method is used to determine the weight of each evaluation criteria without survey. The suggested method based on PROMETHEE with Entropy method is applied to BongHwa region to verify its applicability. After applied, the method successfully assesses the relative risk of flash flood occurrence of each sub region in the BongHwa region. Out of the seventeen sub-regions, five, seven and five of them are evaluated as high-risk, medium-risk, and low-risk, respectively. To verify the results, we searched the historical data of flash flood and the flash flood had occurred in one of high-risk sub-regions at 2008.

• Journal of the Korean Association of Geographic Information Studies
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• v.11 no.1
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• pp.58-67
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• 2008

Topography factors, as homeostasis variables at forest fire, affect the formation of fuel load patterns, atmospheric phenomena and forest fire behavior. Examination of the correlation between landforms and fire severity is important to decision making for fire hazard analysis and fighting strategies. In this study, fire severity was analyzed using Normalized Burn Ratio(NBR) derived from pre- and post-fire Landsat TM/+ETM images and landform were classified based on Topographic Position Index(TPI) in Samcheok(2000), Cheongyang(2002), and Yangyang(2005) forest fire regions. F-tests and Duncan's multi-range test between landform and fire severity showed that fire severities of headwater, high ridges, and upper slopes is higher than ones of local ridges, midslope ridges, and plains. Fire severity were more sensitive in coniferous forest than broadleaf forests.

• Asian Journal of Atmospheric Environment
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• v.5 no.4
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• pp.247-262
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• 2011

This study assessed the health risks of childhood exposure to PBDEs via different possible pathways in children's facilities and indoor playgrounds. When PBDE contamination was measured, it was determined through multiple routes, including inhalation of indoor dust, dermal contact with product surfaces and children's hands, and incidental dust ingestion. Samples were collected from various children's facilities (playrooms, daycare centers, kindergartens, and indoor playgrounds) during summer (Jul-Sep, 2007) and winter (Jan-Feb, 2008). The hazard index (HI) was estimated for non-carcinogens, and PBDEs, such as TeBDE, PeBDE, HxBDE, and DeBDE, were examined. The sensitivity to the compounds did not exceed 1.0 (HI) for any of the subjects in any facility. However, current data about toxicity does not reflect effects that were fully sensitive in children, so there is uncertainty in the dose-response data. The contribution rates of PBDEs were 71.4 to 96.1% and 3.7 to 28.2% for intake and inhalation exposure, respectively, indicating that intake of floor dust and inhalation are the primary routes.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.5
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• pp.1939-1944
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• 2015

MicroRNA-27a (miR-27a) is deemed to be an oncogene that plays an important role in development of various cancers, and single nucleotide polymorphism (SNP) of miR-27a can influence the maturation or aberrant expression of hsa-miR27a, resulting in increased risk of cancer and poor prognosis for non-small cell lung cancer (NSCLC). This study aimed to assess the effects of rs895819 within miR-27a on susceptibility and prognosis of NSCLC patients in 560 clinical confirmed cases and 568 healthy check-up individuals. Adjusted odds/hazard ratios (ORs/HRs) and 95% confidential intervals (CIs) were calculated to evaluate the association between rs895819 and the risk and prognosis of NSCLC. The results showed that allele A and genotype GG of rs895819 were significantly associated with an increased risk of NSCLC (38.9% vs 30.8%, adjusted OR=1.26, 95%CI=1.23-1.29 for allele G vs A; 18.1% vs 11.7%, adjusted OR=1.67, 95%CI=1.59-1.75 for genotype GG vs AA). Moreover, positive associations were also observed in dominant and recessive models (53.7% vs 49.9%, adjusted OR=1.17, 95%CI=1.13-1.20 for GG/AG vs AA; 18.1% vs 11.7%, adjusted=1.65, 95%CI=1.58-1.73). However, no significant association was found between rs895819 and the prognosis of NSCLC in genotype, dominant and recessive models. These results suggested that miR-27a might be involved in NSCLC carcinogenesis, but not in progression of NSCLC. The allele G, genotype GG and allele G carrier (GG/AG vs AA) of rs895819 might be genetic susceptible factors for NSCLC. Further multi-central, large sample size and well-designed prospective studies as well as functional studies are warranted to verify our findings.

• The korean journal of orthodontics
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• v.46 no.2
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• pp.104-110
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• 2016

Objective: Traditional retainers (both metal and fiber-reinforced composite [FRC]) have limitations, and a retainer made from more flexible ligature wires might be advantageous. We aimed to compare an experimental design with two traditional retainers. Methods: In this prospective preliminary clinical trial, 150 post-treatment patients were enrolled and randomly divided into three groups of 50 patients each to receive mandibular canine-to-canine retainers made of FRC, flexible spiral wire (FSW), and twisted wire (TW). The patients were monitored monthly. The time at which the first signs of breakage/debonding were detected was recorded. The success rates of the retainers were compared using chi-squared, Kaplan-Meier, and Cox proportional-hazard regression analyses (${\alpha}=0.05$). Results: In total, 42 patients in the FRC group, 41 in the FSW group, and 45 in the TW group completed the study. The 2-year failure rates were 35.7% in the FRC group, 26.8% in the FSW group, and 17.8% in the TW group. These rates differed insignificantly (chi-squared p = 0.167). According to the Kaplan-Meier analysis, failure occurred at 19.95 months in the FRC group, 21.37 months in the FSW group, and 22.36 months in the TW group. The differences between the survival rates in the three groups were not significant (Cox regression p = 0.146). Conclusions: Although the failure rate of the experimental retainer was two times lower than that of the FRC retainer, the difference was not statistically significant. The experimental TW retainer was successful, and larger studies are warranted to verify these results.

• 한국방재학회:학술대회논문집
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• 2011.02a
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• pp.75-75
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• 2011

본 논문에서는 진동중인 교량 거더에 작용하는 풍하중을 산정하고 그에 따른 플러터 발생풍속을 예측하기 위하여 분산형 전산환경을 활용한 수치해석 연구를 수행하였다. 분산형 전산환경은 웹 포탈을 기반으로 수치해석 환경을 제공하는 수치풍동 시스템으로서, 전산유체역학(CFD : Computational Fluid Dynamics)에 대한 전문지식이 부족한 사용자들도 격자생성, 수치해석자를 이용한 계산, 가시화 등의 전 과정을 편리하게 수행할 수 있는 차세대 토목분야 연구 환경이다. 본 시스템은 그리드스피어(GfidSphere)를 기반으로 구성되었으며, 기본적으로 사용자 관리, 세션 관리, 그룹 관리, 레이아웃 관리 등을 제공하여 사용자가 포탈을 통해서 다양한 서비스를 쉽게 사용할 수 있는 환경을 구축하도록 도와준다. 수치해석을 위한 유체 지배방정식은 2차원 비정상 비압축성 RANS(Reynolds-Averaged Navier-Stokes) 방정식이며, pseudo compressibility 방법을 적용하였다. 비정상 유동장을 해석하기 위하여 이중시간 전진법(dual time stepping)을 사용하였으며, 수렴가속화를 위해 Multi-grid 기법을 적용하였다. 또한 난류 유동장 해석을 위해서 $k-{\omega}$ SST 난류 모델을 사용하였으며, 난류 천이 과정에서의 유동을 모사하기 위하여 Total stress limitation 방법을 적용하였다. 교량 거더의 연직과 회전방향의 2자유도 움직임을 모사하기 위하여 동적격자 기법을 도입하였다. 교량 거더 주변의 비정상 유동해석 결과를 통해, 거더 표면에서 떨어져나가는 크고 작은 와류의 영향으로 양력 및 모멘트 계수 그래프가 중첩된 진폭과 주기를 갖고 주기적으로 나타나는 것을 확인할 수 있었다. 또한 계산된 비정상 공기력을 적용한 2자유도 플러터 방정식을 통하여 플러터 발생풍속을 산정하였다. 최종적으로 본 연구에서 계산된 결과의 타당성을 검증하기 위하여 수치적으로 구한 플러터 발생풍속과 기존의 실험 및 수치해석 결과를 비교하였으며, 결과는 잘 일치하였다.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.1
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• pp.381-386
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• 2013

Aims: The aim of this study was to investigate the effects of adjuvant chemotherapy cycles on the prognosis of patients with post-operative stomach cancer through retrospective analysis. Methods: A total of 128 patients with gastric cancer who underwent gastrectomy, followed by adjuvant chemotherapy consisting of epirubicin, cisplatin or oxaliplatin, leucovorin, and 5-fluorouracil, according to a defined schedule, were divided into three groups according to the number of chemotherapy cycles: Group I (<6 cycles); Group II (6 cycles); and Group III (>6 cycles). Results: The 5-year overall survival (OS) was 20.8% in Group I, 45.0% in Group II, and 42.9% in Group III, with a median follow-up of 43 months. The 5-year relapse-free survival (RFS) was 15.1% in Group I, 40% in Group II, and 40% in Group III. The OS and RFS in Groups II and III were significantly better than in Group I (OS, p = 0.002 and p=0.003; RFS, P<0.001 and P=0.002). There was no difference in OS (p = 0.970) or in RFS (p = 0.722) between Groups II and III. Multivariate Cox hazard analysis determined that the number of adjuvant chemotherapy cycles was an independent factor that influenced OS and RFS. Conclusion: Six cycles of adjuvant chemotherapy gave encouraging outcomes in patients with resectable gastric cancer. Further prospective randomized controlled investigations are warranted in a multi-center setting.

• Journal of the Earthquake Engineering Society of Korea
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• v.9 no.3 s.43
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• pp.23-32
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• 2005

Torsional behavior of eccentric structure under seismic leading may cause the stress and/or deformation concentration, which arouse the failure of the structure in an unexpected manner. This study suggests D-R relationship which shows the overall displacement and rotation of the system based on the ultimate displacement capacity of the each lateral load resistant member. Using the suggested D-R relationship and displacement spectrum, the seismic assessment is conducted and verified in comparison with the time history analysis result. Multi-level seismic assessment Is considered which takes multiple seismic hazard levels and respective performance levels into account. Finally, based on the seismic assessment result, seismic rehabilitation process is presented. In this research, two rehabilitation methods are considered. One is done by means of stiffening/strengthening the seismic resistant members, and the other is based on the member ductility. Especially, in the first method, to optimize the rehabilitation result, the rehabilitation problem is modeled as an optimization problem, and solved using BFGS quasi-Newton optimization method.