• Applied Chemistry for Engineering
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• v.21 no.5
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• pp.495-499
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• 2010

To develop chemical and biosensors, this paper studies sensing characteristics of bulk carbon nanotube (CNT) electrodes by means of their electrical impedance properties due to their large surface area and excellence chemical absorptivity. The sensors were fabricated in the form of film and nano web style by using composite process for mass production. The bulk composite electrodes were fabricated with singlewall and multi-wall carbon nanotubes based on host polymers such as Nafion and PAN, using a solution-casting and an electrospinning technique. The resistance and the capacitance of electrodes were measured with LCR meter under the various amounts of buffer solution to study the electrical impedance change properties of them. On the experimental of sensor electrode, impedance characteristics of the composite electrode are affected by its host polymer and nanofiller and its sensing response showed saturated result after applying some amounts of buffer solution for test chemical. Especially, the capacitance values showed drastic changes while the resistance values only changed within few percent range. It is deduced that the ions in the solution penetrated and diffused into the electrodes surface changed the electrical properties of the electrodes much like a doping effect.

• Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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• v.26 no.3
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• pp.227-239
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• 2008

Processing LiDAR (Light Detection And Ranging) data obtained from ALS (Airborne Laser Scanning) systems mainly involves organization and segmentation of the data for 3D object modeling and mapping purposes. The ALS systems are viable and becoming more mature technology in various applications. ALS technology requires complex integration of optics, opto-mechanics and electronics in the multi-sensor components, Le. data captured from GPS, INS and laser scanner. In this study, digital image processing techniques mainly were implemented to gray level coded image of the LiDAR data for building extraction and superstructures segmentation. One of the advantages to use gray level image is easy to apply various existing digital image processing algorithms. Gridding and quantization of the raw LiDAR data into limited gray level might introduce smoothing effect and loss of the detail information. However, smoothed surface data that are more suitable for surface patch segmentation and modeling could be obtained by the quantization of the height values. The building boundaries were precisely extracted by the robust edge detection operator and regularized with shape constraints. As for segmentation of the roof structures, basically region growing based and gap filling segmentation methods were implemented. The results present that various image processing methods are applicable to extract buildings and to segment surface patches of the superstructures on the roofs. Finally, conceptual methodology for extracting characteristic information to reconstruct roof shapes was proposed. Statistical and geometric properties were utilized to segment and model superstructures. The simulation results show that segmentation of the roof surface patches and modeling were possible with the proposed method.

• Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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• v.26 no.3
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• pp.241-253
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• 2008

Recently, it is appearing that new paradigm of urban planning that ubiquitous concept such as the u-City, uECO-City is introduced while is rising necessity about third dimensional geo-spatial information of high quality for urban area. Orthophoto can manufacture by expense and time that is less easily than digital map using personal computer even if is not highly technician and according as position relation between manmade feature and natural feature is equal, can get information of distance, angle, horizontal and vertical position coordinate of topographic, area etc.. directly through orthophoto. Also, visual effect is good that orthophoto is expressed by image and interpretation is easy to detailed part of topographic. Manufacture and practical use are consisting in various field, for it is having advantage that can recognize information effectively than digital map. Therefore, this study presents a way of generating a detailed DSM for producing a true-orthphoto of the urban area, and this study also presents a way to produce an optimum true-orthophoto for an urban area by investigating through experiment the optimum variable for the geometric and radiometric correction of the orthophoto. This study also examined the potentials of the thesis by building a 3-dimensional city model of the model region with the above thesis on optimum generating method.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• v.2 no.1
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• pp.59-64
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• 1999

Purpose: The aims of this study are to measure the serum levels of fat soluble vitamins (vitamin A and D) from bile duct ligated rats, and to evaluate the effect of oral bile acids administration to facilitate absorption of fat soluble vitamins. Methods: We measured serum ALT, total bilirubin, vitamin A, and vitamin D of Sprague-Dawley rats 1 week before and 4 weeks after experimental bile duct ligation. Rats were consisted with 3 groups. Group 2 had been fed bile acids and group 3 ursodeoxycholic acid after operation for 4 weeks. Multi-vitamin was given to all groups. Results: 1) Base line (mean value before duct ligation): ALT 74.2 IU, total bilirubin 0.26 mg/dL; vitamin D 13.01 ng/mL vitamin A $0.87\;{\mu}g/mL$, total bile acids $25.16\;{\mu}mol/L$. 2) Four weeks after ligation: ALT 100.7 IU, total bilirubin 2.58 mg/dL; vitamin D 7.89 ng/mL vitamin A $1.37{\mu}g/mL$, total bile acids $278.22\;{\mu}mol/L$. 3) 4 weeks after ligation, each group (group 1, group 2 and group 3) showed vitamin D (7.62, 8.10 and 7.99) ng/mL, vitamin A (1.68, 1.06 and 1.33) ${\mu}g/mL$, total bile acids (233.17, 345.80 and 268.57) ${\mu}mol/L$, which were statistically not significant. Conclusion: Serum level of vitamin A is increased after bile duct ligation although vitamin D is decreased. Oral administration of bile acids does not affect the serum levels of vitamin A and D in bile duct ligated rats.

• Journal of the Korean Society of Groundwater Environment
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• v.3 no.1
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• pp.27-36
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• 1996

The Nanji landfill is one of the biggest uncontrolled landfill in terms of its size and scale in the world. Because the landfill was constructed on the very vulnerable alluvial deposit installing no pollution control systems such as bottom liner and leachate collection systems, it has caused a serious adverse effect to near-by groundwater and surface water systems. A through remedial investigation comprising plume detection and site-characterization was performed to design the remedial measure. As a part the investigation, comprehensive water quality study was conducted, using ten existing observation wells and one bundle type monitoring well, to determine the contaminant indicators for the plume delineation and to define the vertical and horizontal variation of specific contaminants via distances from the landfill. The results clearly shows that EC and temperature are a good pollution indicators and the vertical concentrations of specific contaminants measured in the fully screened wells are 20 to 90% more than those measured at the same depth in bundle type well which is located just 2 m apart. This paper presents a cost effective monitoring and sampling method to define the contaminant plume and obtain a basic data for leachate control measures.

• Journal of Technology Innovation
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• v.1 no.1
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• pp.157-169
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• 1993

최근, 시장환경 및 생산구조의 변화에 따라 이른바 첨단생산기술(advanced manufacturing technologies)의 개발과 활용이 산업계 및 학계의 큰 관심을 끌고 있다. 그러나 첨단생산기술의 급속한 기술적 발전과 전략적 가치의 증가에도 불구하고 산업에의 확산은 상대적으로 부진한 현실이다. 이러한 현상은 물론 초기 투자의 재원도달 문제에 기인한다고 말할 수 있지만 일차적으로는 적절한 대안을 선정하고 투자의 정당성을 분석하는 방법론의 미비도 그 원인으로 지적되고 있다. 본 고는 전통적(conventional) 생산기술과 비교한 첨단생산기술과 비교한 첨단생산기술의 특성에 대한 이해를 기초로, 새로운 기술대안들을 비교 분석하는 구체적인 기법의 개발에 관한 접근의 방향성과 개념의 틀(framework)을 제시하는 데 그 목적이 있다. 첨단생산기술의 대안선정과 정당성분석은 다음과 몇 가지 특성을 지니고 있다. 첫째, 투자대안의 속성이 다양하며(multi-attribute) 각각의 속성이 상위 적(conflicting)일 수 있다. 둘째, 기술대안들의 잠재적 기능이 생산체제의 신축성과 유연성(flexible)의 제고를 강조하고 있다. 셋째, 개별기술의 통합을 통해 시스템 전체의 상승효과(synergy effect)를 추구하고 있다. 따라서 이러한 특성에 대한 인식을 토대로 정량적이고 전략적인 장·단점에 대한 고려를 포함하는 종합적이고 객관적인 분석의 틀과 기법이 사용되지 않으면 첨단생산기술의 성공적인 도입과 활용은 기대하기 어려운 것이다. 새로운 생산기술의 도입이 공정의 부분적 개선을 위한 소규모 투자일 경우에는 경제성의 분석을 위해서는 전통적인 재무관리(capital budgeting) 기법들이 이용될 수 있고 직접적인 공정개선의 효과분석을 위해서는 시뮬레이션을 적용하는 것이 바람직하다고 할 수 있다. 그러나 기술대안의 규모가 크고 따라서 그 파급효과가 전체공정으로 확산되는 대규모 사업일 경우에는 다양한 장·단점들을 고려하는 종합적인 접근의 틀이 필요하게 된다. 이러한 방법들을 크게 세 가지 형태로 나누어 보면 (1) 모든 대안들에 대해, 모든 요소들에 관한 비교분석을 동시에 실시하는 동시적 접근(simultaneous approach), (2) 대안 또는 요소들을 그 성격에 따라 계층적 구조로 분할하고 단계별로 비교분석을 실시하는 계층적 접근(hierarchical approach), (3) 요소들을 속성에 따라 몇 개의 소그룹으로 나누고 각 그룹에 대해 순차적으로 대안들을 비교분석 함으로써 고려대상이 되는 대안들을 줄여나가는 순차적 접근(sequtial approach)등을 들 수 있다 이러한 접근법들의 장·단점들을 사업의 규모나 복잡성에 따라 달라지게 된다. 또한 동일한 접근방법 내에서도 구체적인 기법의 선택과 개발도 문제의 특성에 따라 달리 결정되어야 한다. 그러나 어떠한 경우에도 오늘날의 첨단생산기술에의 투자는 현금의 흐름에 대한 계량적 분석에만 의존하는 전통적인 기법만으로는 불충분하며 기업목표와 생산조직 전반에 관한 전략적 요소들을 포함하는 종합적인 접근이 바람직하다.

• Journal of Society of Preventive Korean Medicine
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• v.21 no.2
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• pp.1-13
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• 2017

Objectives : This paper serves to explore current trends of systems biology in Traditional Chinese Medicine (TCM) and examine how it may influence the Traditional Korean medicine. Methods : Literature review method was collectively used to classify Introduction to systems biology, diagnosis and syndrome classification of systems biology in TCM perspective, physiotherapy including acupuncture, herbs and formula functions, TCM systems biology, and directions of academic development. Results : The term 'Systems biology' is coined as a combination of systems science and biology. It is a field of study that tries to understand living organism by establishing a theory based on an ideal model that analyzes and predicts the desired output with understanding of interrelationships and dynamics between variables. Systems biology has an integrated and multi-dimensional nature that observes the interaction among the elements constructing the network. The current state of systems biology in TCM is categorized into 4 parts: diagnosis and syndrome, physical therapy, herbs and formulas and academic development of TCM systems biology and its technology. Diagnosis and syndrome field is focusing on developing TCM into personalized medicine by clarifying Kidney yin deficiency patterns and metabolic differences among five patterns of diabetes and analyzing plasma metabolism and biomarkers of coronary heart disease patients. In the field of physical therapy such as acupuncture and moxibustion, researchers discovered the effect of stimulating acupoint ST40 on gene expression and the effects of acupuncture on treating functional dyspepsia and acute ischemic stroke. Herbs and formulas were analyzed with TCM network pharmacology. The therapeutic mechanisms of Si Wu Tang and its series formulas are explained by identifying potential active substances, targets and mechanism of action, including metabolic pathways of amino acid and fatty acid. For the academic development of TCM systems biology and its technology, it is necessary to integrate massive database, integrate pharmacokinetics and pharmacodynamics, as well as systems biology. It is also essential to establish a platform to maximize herbal treatment through accumulation of research data and diseases-specific, or drug-specific network combined with clinical experiences, and identify functions and roles of molecules in herbs and conduct animal-based studies within TCM frame. So far, few literature reviews exist for systems biology in traditional Korean medicine and they merely re-examine known efficacies of simple substances, herbs and formulas. For the future, it is necessary to identify specific mechanisms of working agents and targets to maximize the effects of traditional medicine modalities. Conclusions : Systems biology is widely accepted and studied in TCM and already advanced into a field known as 'TCM systems biology', which calls for the study of incorporating TCM and systems biology. It is time for traditional Korean medicine to acknowledge the importance of systems biology and present scientific basis of traditional medicine and establish the principles of diagnosis, prevention and treatment of diseases. By doing so, traditional Korean medicine would be innovated and further developed into a personalized medicine.

• Journal of Korea Water Resources Association
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• v.40 no.7
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• pp.503-510
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• 2007

In the area of such a nature-friendly stream improvement, it is not established yet which engineering method is suitable for stream environment, due to lack of technology. Therefore, although nature-friendly stream improvement was done with expensive engineering method, the effect has not been fully confirmed, which results from the absence of overall valuation tool of stream improvement. In this regard, it is necessary to develop and apply comprehensive and diverse valuation methods covering stream functions to the analysis of stream improvement. In this study, we collected data from years' of monitoring on the Gyeongcheon river, which is located in Sunchang-eup, Jeollabuk-do and recently underwent an nature-friendly stream improvement work. Based on the data, we developed a series of valuation methods such as stream naturalness evaluation, life cycle evaluation, amenity evaluation, and economic benefit analysis to consider the environmental function of stream from a comprehensive perspective. Stream naturalness evaluation is a quantitative analysis of how natural a stream is, and includes additional valuation items such as ecosystem and water quality for the purpose of overall valuation, unlike existing research focusing on physical elements and structural characteristics of a stream. We developed a method of stream valuation with life cycle assessment to river reorganization project. Amenity evaluation method was developed as a means to analyze residents' satisfaction with stream improvement through questionnaires. Economic benefit analysis was developed as a means to determine the attributes of environmental water supply, ecosystem, river maintenance, and water quality and predict economic benefits using contingent valuation method (CVM) and multi-attribute utility analysis (MAUA) method in order to analyze economic benefits brought in by stream improvement. It is considered that the four methods developed in this study make possible to conduct an overall and quantitative analysis of stream improvement.

• Proceedings of the Korean Vacuum Society Conference
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• 2012.02a
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• pp.246-246
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• 2012

Smart catalyst design though novel catalyst preparation methods can improve catalytic activity of transition metals on reducible oxide supports such as titania by enhancement of metal oxide interface effects. In this work, we investigated Pt nanoparticles/titania catalysts under CO oxidation reaction by using novel preparation methods in order to enhance its catalytic activity by optimizing metal oxide interface. Arc plasma deposition (APD) and metal impregnation techniques are employed to achieve Pt metal deposition on titania supports which are prepared by multi-target sputtering and Sol-gel techniques. In order to tailor metal-support interface for catalytic CO oxidation reaction, Pt nanoparticles and thin films are deposited in varying surface coverages on sputtered titania films using APD. To assess the role of oxide support at the interface, APD-Pt is deposited on sputtered and Sol-gel prepared titania films. Lastly, characteristics of APD-Pt process are compared with Pt impregnation technique. Our results show that activity of Pt nanoparticles is improved when supported over Sol-Gel prepared titania than sputtered titania film. It is suggested that this enhanced activity can be partly ascribed to a very rough titania surface with the higher free metal surface area and higher number of sites at the interface between the metal and the support. Also, APD-Pt shows superior catalytic activity under CO oxidation as compared to Pt impregnation on sputtered titania support. XPS results show that bulk oxide is formed on Pt when deposited through impregnation and has higher proportion of oxidized Pt in the form of $Pt^{2+/4+}$ oxidation states than Pt metal. APD-Pt shows, however, mild oxidation with large proportion of active Pt metal. APD-Pt also shows trend of increasing CO oxidation activity with number of shots. The activity continues to increase with surface coverage beyond 100%, thus suggesting a very rough and porous Pt films with higher active surface metal sites due to an increased surface area available for the reactant CO and $O_2$ molecules. The results suggest a novel approach for systematic investigation into metal oxide interface by rational catalysts design which can be extended to other metal-support systems in the future.

• Korean Journal of Environmental Agriculture
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• v.31 no.2
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• pp.164-169
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• 2012

BACKGROUND: This study was conducted to monitor the residue of pesticides and to assess their risk in domestic agricultural products, such as fruit vegetables, tomatoes, oriental melons and root vegetables, garlic, potatoes and onions. METHODS AND RESULTS: 250 samples containing both general and environment-friendly certified agricultural products were collected from traditional markets and supermarkets in 6 cities. 132 pesticides except for herbicides were analysed using the multi-residue methods by GC/ECD, GC/NPD and HPLC/UVD. 17 kinds of pesticides were detected from 42 samples, which were 32 general, 1 organic, 4 pesticide-free and 5 low pesticide agricultural products. Among those, myclobutanil detected in 1 potato and procymidone detected in 10 oriental melons were unregistered pesticides for using in Korea. Fenbuconazole detected in 1 potato and phorate detected in 1 tomato were exceeded over the MRLs established by Korea Food and Drug Administration. CONCLUSION: Based on these results, a risk assesment was conducted using a percentage of acceptable daily intake(%ADI). %ADI ranged from 0.0064% to 4.6035%, and showed these values have no effect on human health.