• 대한두경부종양학회지
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• 제9권1호
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• pp.74-87
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• 1993

Immunohistochemical studies on S-100 protein and lactoferrin were carried out to evaluate the existence and distribution pattern of S-100 protein and lactoferrin positive cells in salivary gland tumors. The specimens used were 25 cases of pleomorphic adenoma, 2 cases of monomorphic adenoma, 2 cases of mucoepidermoid tumor, 2 cases of acinic cell tumor, 3 cases of adenoid cystic carcinoma and 2 cases of adenocarcinoma occured in parotid and submandibular salivary gland. ABC kits(Dako corp. Copenhagen. Denmark) for S-100 protein and lactoferrin were used. The results obtained were summarized as follows: In the normal salivary gland. positive immunoreaction for S-100 protein was observed in myoepithelial cells of acini and intercalated ducts. Positive immunoreaction for lactoferrin was observed in serous acinic cells, epithelial cells of intercalated ducts, and excretory material in the ductal lumina. In the pleomorphic and monomorphic adenomas. most of tumor cells were positive for S-100 protein, while luminal tumor cells in gland-like or duct-like structures were rarely positive for lactoferrin. In mucoepidermoid tumor, most of squamous cells and a few of intermediate cells were positive for S-100 protein, but all of tumor cells were negative for lactoferrin. In acinic cell tumor, most of tumor cells were positive for lactoferrin, but all of tumor cells were negative for S-100 protein. In adenoid cystic carcinoma, basaloid tumor cells in trabecular structure were focally positive for S-100 protein. and in adenocarcinoma, many of tumor cells were posivive for both S-100 protein and lactoferrin. Thus, according to the embryonic stage of the development of the tumor cell origin, it was possible to classify the salivary gland tumor as followings: mucoepidermoid carcinoma which originated from the earliest stage, acinic cell tumor which originated from the end stage. Between these two extremes, there were pleomorphic adenoma, adenoid cystic carcinoma and adenocarcinoma which originated in the middle stage of the development of .the salivary glands. Based on the above results, it can be stated that S-100 protein is demonstrated in tumor cells orginated from myoepithelial cells and lactoferrin in glandular differentiated tumor cells.

• Maxillofacial Plastic and Reconstructive Surgery
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• 제19권1호
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• pp.70-78
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• 1997

Mucoepidermoid carcinoma occurs more freguently than any other in the major sacivary glands. It is relatively more common in parotid than in submandibular gland. Stewart at al published the first large series of these tumors in 1945 and suggested the name "Mocoepidermoid tumor". Now it is divided three categories : low-grade, intermediate-grade, high-grade. And Mucoepidermoid carcinomas are composed of mucous cells, epidermoid cells, and intermediate cells. We freated low-grade mucoepidermoid carcinoma patient with induction chemotherapy, surpery, and adjuvomt chemotherapy.

• 대한두경부종양학회지
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• 제28권1호
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• pp.31-33
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• 2012

Mucoepidermoid carcinoma is most frequent malignant tumor of parotid gland. However, mucoepidermoid carcinoma arising from pleomorphic adenoma has been disputed and rarely reported. 54-year-old woman with pleomorphic adenoma underwent superficial parotidectomy. And 15 years later, she diagnosed mucoepidermoid carcinoma at the same side. We report the case with a review of literature.

• Journal of Chest Surgery
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• 제21권5호
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• pp.941-947
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• 1988

The mucoepidermoid carcinoma of the bronchus is very rare neoplasm. The histological appearance is an intimate mixture of mucous-producing cell and epidermoid cell. The malignant potency of the tumor was determined by histologic pattern. Bronchoplasty techniques represent the ideal form of excisional therapy for benign endobronchial tumor as well as tumors of low-grade malignant potential, such as bronchial adenoma, and for repair of traumatic airway injuries and benign stricture and selected group of patients with carcinoma of the lung. We experienced a case of-low-grade mucoepidermoid carcinoma in a patient of 21-year old male who has been suffered from hemoptysis episodes for several years. The sleeve resection of left main bronchus and left lower lobectomy due to bronchiectatic change were carried out. The patient are being followed up without specific problem.

• Journal of Chest Surgery
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• 제35권10호
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• pp.760-763
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• 2002

기관지에서 발생한 점막표피양 종양은 매우 드물게 발생하는 종양으로 특히 국내에서 13세 이하 소아에서는 아직 보고된 바가 없다. 대개는 기관지 폐쇄에 의한 증상으로 발견되어 흔히 결핵으로 오인되기도 한다. 종양의 악성여부와 원위부 전이가 흔치 않아 수술적 완전 절제가 치료 원칙이며 예후는 조직학적 분류에 의해 결정된다. 본원에서는 기침과 열을 주소로 한 10세 남아에서 기관지 내시경을 통한 생검과 개흉술 통한 우 중, 하엽절제술을 시행하여 성공적으로 종양을 제거하였기에 여러 문헌 고찰과 더불어 보고하는 바이다.

• 대한두경부종양학회지
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• 제2권1호
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• pp.33-39
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• 1986

This is a clinical analysis of 24 cases of parotid gland tumor who were treated in the department of Surgery, Chonnam National University Medical School during the past 10years from January, 1976 to December, 1985. According to this analysis of total 24 cases, we concluded as follows; 1) 21 cases were benign tumors and 3 cases were malignant tumors. As the histopathological findings, benign tumor included 88%and malignant tumor 12%. Majority of benign tumor contained mixed tumor(86.7%), and the malignant tumor contained mucoepidermoid carcinoma (66.7%). 2) The peak age incidence was 40th in benign tumor and 50th in malignant tumor. 3) The chief complaints of patient was a painless mass and the duration of illness was average 5.2 years. 4) The mean size of mass was 4.5cm in diameter. 5) The surgical procedures were performed with excision 6 cases, superficial lobectomy 8 cases, wide excision with partial parotidectomy 4 cases, total parotidectomy 3 cases in benign tumors. In malignant tumors, total parotidectomy 2 cases and wide excision with partial parotidectomy 1 case were performed. 6) Major postoperative complications such as facial nerve palsy 7 cases (temporary ; 5 cases, permanent; 2 cases), Frey syndrome 1 case, seroma 1 case, hematoma 1 case, and wound infection 1 case were developed. The recurrence contained pleomorphic adenoma 1 case and mucoepidermoid carcinoma 1 case.

• 대한기관식도과학회지
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• 제4권2호
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• pp.225-230
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• 1998

폐에 발생하는 점액표피양 암종은 기관 및 기관지 점막하선에서 발생하는 드문 악성종양이다. 저자들은 좌측 주기관지와 우측중간 기관지에 발생한 점액표피양 암종을 각각 수상절제술 및 폐엽절제술로 치료하였다. 수술 후 별 합병증 없이 각각 3년, 18개월간 추적관찰중이다.

• Maxillofacial Plastic and Reconstructive Surgery
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• 제20권4호
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• pp.383-387
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• 1998

The mucoepidermoid carcinoma is classified as either well, moderately, or poorly differentiated. The criteria used to classify the lesions are discussed, and pathologic features are illustrated. The most important factors in prognosis are : 1. degree of histologic differentiation, and 2. presence or abscence of tumor on the lines of surgical excision. Recurrences rates are correlated with histologic differentiation. Stewart, Foote, and Becker in 1945 coined the term "mucoepidermoid tumor" to discribe an unusual salivary neoplasm containing epidermoid and mucus-secreting cells which was thought to arise in salivsary gland ducts. The treatment of the mucoepidermoid carcinoma is chiefly surgical, although recent data have shown favorable responses to radiation therapy. Currently, surgery followed by radiation treatment is recommended for intermediate-grade and high-grade tumors ; low-grade tumors can be managed by surgery alone. Authors present a case of mucoepidermoid carcinoma managed with wide surgical resection and postoperative irradiation and showing a good clinical result with review of literatures.

• Tuberculosis and Respiratory Diseases
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• 제44권5호
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• pp.1132-1139
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• 1997

기관지에서 점액상피양 종양은 드문 병변으로 대부분은 임상적으로 양성 경과를 보이는 저등급 암종이나 때로는 치명적인 고등급 암종을 보일 수 있으며 치료는 병리학적 등급에 관계없이 외과적 절제가 우선이다. 저자들은 호흡곤란을 내원하여 우폐 전체의 허탈 소견을 보인 임신 32주의 여자에서 조직학적으로 확인되어 수술한 저등급의 점액 상피양암 1예를 경험하였기에 문헌고찰과 함께 보고하는 바이다.

• 대한두경부종양학회지
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• 제40권1호
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• pp.27-31
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• 2024

Mucoepidermoid carcinoma is one of the most common malignant tumors that occur in the salivary glands. While several cases of distant metastasis have been reported, instances of metastasis to the skin are rare. We present the case of a 72-year-old man diagnosed with parotid mucoepidermoid carcinoma who experienced temporary remission following surgical resection and adjuvant chemoradiotherapy. However, the carcinoma recurred along the skin at the periauricular area along the mask line. Given the current prevalence of COVID-19, the practice of wearing masks has become more widespread. This case report highlights the recurrence of mucoepidermoid carcinoma along the mask strap line, emphasizing the importance of distinguishing it from benign dermatological conditions.