• Journal of Acupuncture Research
• /
• 제32권1호
• /
• pp.13-22
• /
• 2015

Objectives : Alcohol-related liver disease is a major cause of morbidity and mortality worldwide. The present study was undertaken to determine whether Ganoderma lucidum pharmacopuncture(GLP) could protect against chronic liver injury induced by ethanol intoxication in rats. Methods : Sprague-Dawley rats were divided into 4 groups: normal, control, normal saline pharmacopuncture(NP), and GLP, with 8 animals in each. Each group, except normal, received ethanol orally. The NP and GLP groups were treated daily with NP and GLP respectively. The control group was not treated. All rats except the normal group were intoxicated for 4 weeks by oral administration of EtOH(6 g/kg BW). Two acupuncture points were used: Qimen($LR_{14}$) and Taechung($LR_3$). Body weight, histopathological analysis, liver function, activities of antioxidant enzymes, and immunohistochemistry were assessed. Results : GLP reduced the histological changes due to chronic liver injury induced by EtOH and significantly reduced the increase in the alanine aminotransferase(ALT) and aspartate aminotransferase(AST) enzymes. It significantly reversed the superoxide dismutase(SOD) and the catalase activities(CAT). It also significantly decreased BAX and increased Bcl-2 immunoreactivity expression. Conclusions : This study showed the protective efficacy of GLP against EtOH-induced chronic liver injury in SD rats by modulating ethanol metabolizing enzymes activity, attenuating oxidative stress, and inhibiting mitochondrial damage-mediated apoptosis.

• Journal of Pharmacopuncture
• /
• 제8권1호
• /
• pp.67-71
• /
• 2005

Objectives : This study was conducted to observe the tip of needles which induce poor needle sensation upon injection of herbal acupuncture. Methods : Among the syringes used for herbal acupuncture, needles which cause poor sensation were collected and evaluated by SEM (scanning electron microscope) for changes in structure, existence of impure matters, physical damage, and etc. Results : 1. Various forms contributed to poor needle sensation. Bent needle body, damaged or crooked needle tip, and blunted tip 2. Poor needles could be made during the manufacturing process, during insertion of the needle into the vial(except for the lubricants), and repeated procedures with one needle at different regions. Conclusion : Poor needles induce unnecessary pain and discomfort not only to the patients but also to administrators during injection. Herbal acupuncture is a treatment technique injecting herbal extract on the meridian points, and strict quality check must be enforced to prevent occurrence of poor needles.

• Journal of Pharmacopuncture
• /
• 제8권1호
• /
• pp.41-44
• /
• 2005

Objectives : This experiment was conducted to reevaluate $LD_{50}$ of Korean bee venom acupuncture as many changes have occurred over the years. Methods : ICR mice were used as the experiment animals and bee venom acupuncture was manufactured under the protocols of Korean Institute of herbal Acupuncture. Based on the previous reports, experiment was divided into pre and main sections. Results : 1. Presumed $LD_{50}$ value is at 5.25mg/kg 2. Deaths of experiment animals occurred within 48 hours. 3. Reduced toxicity of the bee venom acupuncture is likely to be the results of more refined manufacturing process and production. Conclusion : Comparing with the values of the previous results, toxicity of the bee venom acupuncture showed significant changes and more accurate findings on $LD_{50}$ value must be accomplished to lead further studies on the bee venom acupuncture.

• Journal of Physiology & Pathology in Korean Medicine
• /
• 제27권5호
• /
• pp.497-508
• /
• 2013

In addition to our previous study on the diseases and symptoms described in Juan Wooden Slips(居延漢簡), here we focused on therapeutics of Juan Wooden Slips, including herbal medicines, acupuncture, and moxibution. In Juan Wooden Slips, there are 36 species of medicinal herbs and 17 herbal prescriptions. Among the medicinal herbs, 75% of herbs were also used in Shanghanzabing-lun(傷寒雜病論). In terms of efficacy and therapeutic range of the medicinal herbs and prescriptions, Juan Wooden Slips is very similar to Shanghanzabing-lun. In addition, acupuncture were used as a combined with moxibution or herbal remedies similarly to Shanghanzabing-lun. Thus, we suggest that the medical thoughts and technologies shown in Juan Wooden Slips might influence on the establishment of Shanghanzabing-lun.

• Journal of Pharmacopuncture
• /
• 제4권2호
• /
• pp.65-71
• /
• 2001

Objectives : This study was performed to examine the patterns and to prevent the side effects of CF Herbal Acupuncture treatment Methods : We observed 10 patients who complained the side effects of Herbal acupuncture CF and 2 healthy men for the sake of examine the cause from the August 17 to 24, 2001. Results 1. All of the patients complained severe pain, redish, and edema on the side of injections 2. We were able to witness decrease in pain, redish, and edema, after 2days of injection. After 4days, we were unable to any side effects. 3. According to the clinical studies, we came to determine that the CF herbal abstract which caused the side effects were manufactured between 4 to 13 days, August 4. We assume these side effects were caused by minute quantity of toxin remaining in the screw pressor mixed with the CF herbal abstract.

• The Journal of Dong Guk Oriental Medicine
• /
• 제7권2호
• /
• pp.69-79
• /
• 1999

Hemifacial spasm including blepharospasm is characterized by spontaneous clonic an d tonic muscle spasm on one side of the face with synkinesis. Though the etiology of hemifacial spasm is not entirely understood, generally there are two. One is nuclear hypothesis and the other is peripheral hypothesis. There are two ways of treatment of hemifacial spasm. One is internal medicine and the other is operative method. In oriental medicine, hemifacial spasm is very similar to diseases such as Anpojindo (眼胞振跳), Poryunjindo(胞輪振跳), or Aunido(眼眉跳) in symptoms. The diseases such as Anpojindo(眼胞振跳), Poryunjindo(胞輪振跳), Anmido(眼眉跳) is related to the function of liver(肝) and risk factors are regarded as Pung(風). The acupuncture therapy of hemifacial spasm is based on Liver meridian(LV), Gallbladder meridian(GB). And ear-acupuncture is recommended as a good method for hemifacial spasm.

• Journal of Haehwa Medicine
• /
• 제21권1호
• /
• pp.109-115
• /
• 2012

Purpose : This study was designed to evaluate the effects of oriental medicine therapy on a chronic PID(pelvic inflammatory disease). Methods : This patient was treated with oriental medicine of Danchisoyosan(丹梔逍遙散), acupuncture at Qihai(氣海), Guanyuan(關元), Zhongji(中極), Sanyinjiao(三陰交) and Zigong(子宮) and moxibution at Zhongwan(中脘), Guanyuan(關元). Results : After the oriental medical treatments such as oriental medicine, acupuncture and moxibution, improvement was seen in the patient's symptoms such as lower abdomen pain, leukorrhea and chronic fatigue syndrome. Conclusion : This results indicates that the oriental treatment is effective in the treatment of chronic pelvic inflammatory disease.

• Korean Journal of Acupuncture
• /
• 제26권1호
• /
• pp.139-159
• /
• 2009

Objective & Methods : The purpose of this study is to observe the effects of herbal-acupuncture with Lycii Fructus (LF-HA) at KI10 (Eumgok) on osteoporosis in ovariectomized (OVX) ddy mice. We carried out several experimental items which were known to be related with osteoporosis. Results : 1. Tibial BMD was significantly increased in the LF-HA group. 2. Tibial Ca level was significantly increased in the LF-HA group. 3. Osteoclast like cell in tibia was significantly decreased in the LF-HA group. 4. Histological change of tibia was improved, the trabecular bone thickness was significantly increased and the growth plate length was significantly decreased in the LF-HA group. Conclusion : These results suggest that LF-HA at KI10 has therapeutic effects on osteoporosis especially by way of suppressing osteoclast cells in ovariectomized ddy mice.

• Journal of Haehwa Medicine
• /
• 제16권2호
• /
• pp.211-216
• /
• 2007

Objective : This study is designed to find out the effects of indirect moxibustion at Geogol (LI16) on the shoulder pain. Methods : The patients were hospitalized Donghwa oriental medical clinic from 19th Sep. 2006 to 4th Oct. 2006, and treated with indirect moxibution at Geogol (LI16) on the shoulder pain. Results : 1. The effects of treatment by duration was follow : Below 1 month duration was improved highly. 2. The effects of treatment by condition of patients was follow : After treatment, the percentage of above "Good" level was 81%. 3. The effects of treatment by pain region of Meridian part. was follow : pain region of LI(手陽明大腸經) Meridian part was improved highly. Conclusion : According to the results, indirect moxibustion at Geogol (LI16) may be good effects on the shoulder pain.

• Journal of Sasang Constitutional Medicine
• /
• 제14권3호
• /
• pp.181-187
• /
• 2002

The Interior Disease of Taeyangin(太陽人裏病證) is typical syndrome in the Taeyangin pathology taking nausea, vomiting and dyspepsia. However, The Interior Disease of Taeyangin is difficult to classify because Taeyangin patients are relatively few and published studies about Taeyangin pathology are rare. This patient was a 69-year-old man who had nausea, vomiting, dyspepsia and epigastric pain and had been diagnosed and treated as Gastric ulcer before. We classified this patient as The Interior Disease of Taeyangin and prescribed Mihudeungsikjangtang(??藤植腸湯). We experienced the good effect of Mihudeungsikjangtang on The Interior Disease of Taeyangin. We report the healing process and the result of treatment in this study.