• Investigative Magnetic Resonance Imaging
• /
• 제23권2호
• /
• pp.148-156
• /
• 2019

Hyperglycemia-induced hemichorea (HGHC) is a rare but characteristic hyperkinetic movement disorder involving limbs on one side of the body. In a 75-year-old woman with a left-sided HGHC, conventional brain MR imaging showed very subtle T1-hyperintensity and unique gadolinium enhancement in the basal ganglia contralateral to movements. Multi-parametric MRI was acquired using pulse sequence with quantification of relaxation times and proton density by multi-echo acquisition. Myelin map was reconstructed based on new tissue classification modeling. In this case report of multi-parametric MRI, quantitative measurement of myelin change related to HGHC in brain structures and its possible explanations are presented. This is the first study to demonstrate myelin loss related to hyperglycemic insult in multi-parametric quantitative MR imaging.

• 한국엔터테인먼트산업학회논문지
• /
• 제13권4호
• /
• pp.63-70
• /
• 2019

상황 인식 환경에서 공황장애의 증상을 추출하고자 일상생활을 통해 자연스런 음직임에서 발생하는 신체 상황정보를 추출하여 공황장애의 구성요소를 찾아내고 온톨로지 이론을 적용하여 의미를 추론 과정을 거쳐 공황장애에 증상의 정도에 대해 정보를 제공할 수 있다. 온톨로지 기반의 정보 처리를 위해 공황장애의 구성요소는 클래스로 정의하고 공황장애의 상태를 이해할 수 있도록 온톨로지 모델링을 통해 공황장애지수를 도출하였다. 공황장애 구성요소와 공황장애 지수의 도출은 공황장애에 대한 상황 인식 기반의 정보 서비스를 가능할 것이며, 상황인식 기반 디바이스와 결합되어 상황정보는 주기적으로 동기화된다. 공황장애 지수의 결과를 관찰할 수 있으며 공황장애의 요인이 되는 생활습관을 개선하는데 적용할 수 있을 것이다.

• 대한후두음성언어의학회지
• /
• 제25권2호
• /
• pp.82-85
• /
• 2014

Functional dysphonia is a specific voice disorder refers to dysphonia without abnormal anatomical vocal fold findings at larynx. The proportions of this disorder are estimated up to 40% of dysphonia patients at ENT clinics. In this article, we will discuss about other functional dysphonia and neurological dysphonia except for muslce tension dysphonia and spasmodic dysphonia. For details, will describe about phonatory charateristics and treatment options about paradoxical vocal fold motion disorder, mutational dysphonia, essential vocal tremor, conversion dysphonia, and vocal tremor related with parkinson's disease.

• 수면정신생리
• /
• 제30권1호
• /
• pp.9-12
• /
• 2023

Periodic limb movements during sleep (PLMS) are prevalent in various sleep disorders, such as restless legs syndrome (RLS), periodic limb movements disorder, obstructive sleep apnea (OSA), REM sleep behavior disorder (RBD), and narcolepsy. PLMS has been hypothesized to be related to the decline of dopaminergic transmission. In RLS, PLMS is suggested to be related to iron deficiency and symptom severity. PLMD is a rare sleep disorder, and the role of PLMS in PLMD has not been clearly investigated yet. PLMS in OSA, which remain after proper PAP therapy, may need further management. The clinical relevance of PLMS in RBD and narcolepsy have not been investigated thoroughly and need further studies. Whether PLMS are to be considered as a mere symptom of individual sleep disorders or not can be elucidated through studies investigating the efficacy of therapeutic approaches to reduce PLMS in various sleep disorders.

• Annals of Clinical Neurophysiology
• /
• 제14권1호
• /
• pp.7-11
• /
• 2012

Polysomnography is used to diagnose many types of sleep disorders including sleep apnea, periodic limb movement disorder, REM sleep behavior disorder, parasomnias, and narcolepsy. It is a comprehensive recording of the biophysiological changes that occur during sleep. The polysomnography monitors many body functions parameters including EEG, EOG, EMG, ECG, respiratory airflow, respiratory effort, and pulse oximetry during sleep. Multiple Sleep Latency Test (MSLT) is performed for diagnosing narcolepsy and excessive daytime sleepiness. It is usually to be done after an overnight polysomnography. The test consists of four or five 20-minute nap opportunities that are scheduled two hours apart.

• 대한음성언어의학회:학술대회논문집
• /
• 대한음성언어의학회 1997년도 제8회 학술대회 심포지움
• /
• pp.262-262
• /
• 1997

말더듬(stuttering)이란 언어-운동조절의 장애를 일으키는 운동장애(movement disorder)의 일종으로 혀, 입술, 후두를 이루는 근육과 호흡근육 등의 시간적인 부조화(inappropriate timing)로 특징지어지는 유창성장애(fluency disorder)의 하나로 인식되어 왔다. 여태까지 행동치료(behavioral treatment), 정신과적인 치료(psychiatric modalities)등이 치료의 방법으로 이용되어왔으며, 초기에는 비교적 좋은 반응을 보이나 지속적인 효과에 대해서는 회의적인 경우가 많았다. (중략)

• Korean Journal of Radiology
• /
• 제24권3호
• /
• pp.247-258
• /
• 2023

Objective: To localize the neuroanatomical substrate of rapid eye movement sleep behavior disorder (RBD) and to investigate the neuroanatomical locational relationship between RBD and α-synucleinopathy neurodegenerative diseases. Materials and Methods: Using a systematic PubMed search, we identified 19 patients with lesions in different brain regions that caused RBD. First, lesion network mapping was applied to confirm whether the lesion locations causing RBD corresponded to a common brain network. Second, the literature-based RBD lesion network map was validated using neuroimaging findings and locations of brain pathologies at post-mortem in patients with idiopathic RBD (iRBD) who were identified by independent systematic literature search using PubMed. Finally, we assessed the locational relationship between the sites of pathological alterations at the preclinical stage in α-synucleinopathy neurodegenerative diseases and the brain network for RBD. Results: The lesion network mapping showed lesions causing RBD to be localized to a common brain network defined by connectivity to the pons (including the locus coeruleus, dorsal raphe nucleus, central superior nucleus, and ventrolateral periaqueductal gray), regardless of the lesion location. The positive regions in the pons were replicated by the neuroimaging findings in an independent group of patients with iRBD and it coincided with the reported pathological alterations at post-mortem in patients with iRBD. Furthermore, all brain pathological sites at preclinical stages (Braak stages 1-2) in Parkinson's disease (PD) and at brainstem Lewy body disease in dementia with Lewy bodies (DLB) were involved in the brain network identified for RBD. Conclusion: The brain network defined by connectivity to positive pons regions might be the regulatory network loop inducing RBD in humans. In addition, our results suggested that the underlying cause of high phenoconversion rate from iRBD to neurodegenerative α-synucleinopathy might be pathological changes in the preclinical stage of α-synucleinopathy located at the regulatory network loop of RBD.

• Journal of Acupuncture Research
• /
• 제19권1호
• /
• pp.76-83
• /
• 2002

Forteen cases were observed among the Temporomandibular Disorder who were outpatients at the Department of Acupuncture & Moxibustion Oriental Medical Hospital, Dae Jeon University. Objective : To improve the therapeutic rate of Temporomandibular Disorder by treatment of acupuncture, chiropractic therapy and exercise therapy. Methods : Forteen outpatients suffering from Temporomandibular Disorder were treated by acupuncture, chiropractic therapy and exercise therapy. Acupuncture therapy was taken on Waiguan(TE5,外關), Zulingi(G41, 足臨泣), Sidu(TE9, 四瀆), Yanglingquan(G34, 陽陸泉), Qiuxu(G40, 丘墟), Xiaguan(S7, 下關). Chiropractic therapy was taken, when the subluxation of outpatients's Cervical spine was observed. Results : The syndrome of TMD, that is the Pain, the movement disorder and the click sound, was disappeared by 2~3 times acupuncture, chiropractic and exercise therapy.

• 한국전문물리치료학회지
• /
• 제27권2호
• /
• pp.140-148
• /
• 2020

Background: Scapular winging (SW) could be caused by tightness or weakness of the periscapular muscles. Although data mining techniques are useful in classifying or predicting risk of musculoskeletal disorder, predictive models for risk of musculoskeletal disorder using the results of clinical test or quantitative data are scarce. Objects: This study aimed to (1) investigate the difference between young women with and without SW, (2) establish a predictive model for presence of SW, and (3) determine the cutoff value of each variable for predicting the risk of SW using the decision tree method. Methods: Fifty young female subjects participated in this study. To classify the presence of SW as the outcome variable, scapular protractor strength, elbow flexor strength, shoulder internal rotation, and whether the scapula is in the dominant or nondominant side were determined. Results: The classification tree selected scapular protractor strength, shoulder internal rotation range of motion, and whether the scapula is in the dominant or nondominant side as predictor variables. The classification tree model correctly classified 78.79% (p = 0.02) of the training data set. The accuracy obtained by the classification tree on the test data set was 82.35% (p = 0.04). Conclusion: The classification tree showed acceptable accuracy (82.35%) and high specificity (95.65%) but low sensitivity (54.55%). Based on the predictive model in this study, we suggested that 20% of body weight in scapular protractor strength is a meaningful cutoff value for presence of SW.

• 척추신경추나의학회지
• /
• 제1권1호
• /
• pp.51-60
• /
• 2006

Objectives : The purpose of study was to compare and analyze the effects of the distance Acupuncture and the Chuna on Temporomandibular Disorder. Methods : Clinical studies were done on 31 patients who were treated with Temporomandibular Disorder at Dept. of Acupuncture & Moxibusition of Hospital of Ha-na Oriental Medicine from May 23 2005 to Apr 30 2006. Subjects were divided Into two group, Distance acupuncture group and Chuna group. In Distance acupuncture group, we treated patients with Wijungyug(胃正格) or Damjungyug(膽正格). In Chuna group, we treated patients with Distraction & Translation technique. For evaluating Function of Temporomandibular joint of Patients, we use the Modified Craniomandibular Index(mCMI) before treatment and after 6th treatment. Results : In Mandibular Movement(MM) of patients, the patients of Acupuncture Group were more effective than Chuna group. In TMJ noise(TN) of patients, the patients of Chuna Group were more effective than Acupuncture group. Conclusions : The Distance acupuncture may be better effect on Mandibular Movement and The chuna maybe better effect on TMJ noise.