• Journal of Oral Medicine and Pain
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• v.42 no.3
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• pp.62-71
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• 2017

Purpose: The purpose of this study was to examine the rate of salivation before and after olfactory stimulation using BPO (black pepper oil) and then, to collect basic data for screening the possibility of introducing olfactory stimulus to prevent and improve dry mouth. Methods: The subjects in this study were 60 college students in Jeon-Nam province. The subjects were randomly divided into 3 groups; the BPO group (n=20), the lavender oil (LVO) group (n=20), and the distilled water (DW) group (n=20). The amount of whole saliva before and after olfactory stimulation was measured 14 times for a 4-week period. Results: In the BPO and LVO groups, the amount of whole saliva increased after the olfactory stimulation and it was most prominent in the BPO group (p<0.05). The difference of whole salivation was higher in the BPO group (p<0.05) and there was no significant difference in the salivary flow rate in the DW group. After 14 times of measurement for 4 weeks, the BPO and LVO groups showed an increase in salivary rate at an early stage compared without stimulation (p<0.05), but there was no significant difference between the 2 groups in the middle. Since the twelfth measurement, whole saliva secretion increased and maintained the elevated level (p<0.05). Conclusions: The olfactory stimulation using BPO may contribute to stimulating salivation. Further studies are needed for subjects with dry mouth symptoms. In the future, qualitative and quantitative studies should be conducted for people who complains about oral dryness.

• Journal of Korean society of Dental Hygiene
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• v.3 no.2
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• pp.157-168
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• 2003

The purpose of this study was to examine the relationship of oral state and health condition among elderly people. The subjects in this study were 220 senior citizens who were randomly selected from among dwellers in Eunpyeong-gu and Jongno-gu, Seoul. A survey was conducted by one-on-one interview to find out their oral state and health condition. The collected data were analyzed with SPSS 10.0 program, and variance analysis, correlation analysis and regression procedure were employed. The findings of this study were as follows: First, Regarding subjective oral health state, 52.3 percent of the elderly people, more than the half, considered their mouth to be in good health. The number of their mean remaining permanent teeth was 14.85, which was one of the indexes to indicate their objective oral state. Second, Concerning their abnormal oral health experience, 75 percent didn't feel that their masticatory force was good enough, and 55.9 percent felt pain in their teeth, 70.0 percent suffered from mouth dryness. Those fact showed that a lot of the elderly people felt there was something wrong with their oral cavity, and the unhealthy oral state made it difficult for them to eat food, as their masticatory force weakened and they couldn't get a good taste for food. Third, Those who viewed their oral cavity as healthy thought that they were in good shape, and there was a significant correlational relationship between their subjective oral and overall physical health states. Their own perception of oral state made a difference to their subjective health status, and the subjective oral health was significantly related to ADL as well, which implied that their ADL was different according to the way they looked at their own oral health status.

• Sleep Medicine and Psychophysiology
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• v.23 no.2
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• pp.97-99
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• 2016

Positive airway pressure (PAP) is currently recommended as a primary treatment for obstructive sleep apnea syndrome (OSAS) and positively affects various subjective and objective parameters related to OSAS, such as the apnea-hypopnea index, excessive daytime sleepiness, and blood pressure. However, PAP also exhibits various adverse effects, including skin breakdown, pressure intolerance, claustrophobia, unintentional mask removal, mouth leaks, and dryness. Especially, unintentional mask removal due to nasal obstruction may result in poor PAP compliance. A 47-year-old male patient with severe OSAS who had low PAP compliance due to nasal obstruction underwent nasal surgery. After the surgery, nasal obstruction was corrected and the patient experienced improved PAP compliance (from 30.4% to 86.7%). This case demonstrates that nasal surgery may be useful for improving PAP compliance in OSAS patients with nasal obstruction.

• Journal of Korean society of Dental Hygiene
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• v.20 no.5
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• pp.545-559
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• 2020

Objectives: The purpose of this study was to systematically analyze and examine the relationship between the number of lost teeth and quality of life (QoL) among elderly. Methods: Papers published in Korean and English between 2000 and 2020 were searched. Relevant papers were selected by two independent readers according to predefined exclusion criteria. Quality assessment and consistency tests were conducted using ROBIS. Results: Twelve of the 854 studies were targeted, and the analysis confirmed that tooth loss was related to a decrease in the QoL in 11 studies. Tooth loss negatively affected the QoL among the elderly. However, one study indicated that the QoL and number of teeth were not related. Rather, dry mouth affected the QoL, and cavities caused by oral dryness led to tooth loss. Most of the selected studies indicated that the QoL of elderly individuals with a single tooth was higher than that of those with no teeth. Conclusions: This study provides strong evidence that tooth loss in the elderly is associated with impairment of QoL.

• Imaging Science in Dentistry
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• v.51 no.2
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• pp.209-216
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• 2021

Sjögren syndrome is a chronic autoimmune inflammatory disease characterized by lymphocytic infiltration of exocrine glands, predominantly the parotid and lacrimal glands, thereby resulting in oral and ocular dryness. It has been reported to occur most frequently in women between 40 and 50 years of age. Sjögren syndrome has an insidious onset, is slowly progressive, and presents a wide range of clinical manifestations, leading to delays or challenges in the diagnosis. Early diagnosis of this condition is essential to prevent the associated complications that affect patients' quality of life. This report presents 3 cases of Sjögren syndrome in female patients aged between 40 and 75 years who presented with complaints of persistent dry mouth and burning sensation. The cases highlight the diagnostic value of 3-dimensional cone-beam computed tomographic sialography in the detection of salivary gland pathologies at an early stage.

• Journal of Dental Anesthesia and Pain Medicine
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• v.22 no.6
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• pp.395-404
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• 2022

Hydroxyzine is one of the most popular oral sedatives used in pediatric dentistry. This study aimed to investigate the safety and possible side effects of sedation using hydroxyzine in pediatric dentistry. "Hydroxyzine," "Dental sedation," "Child," and "Safety" and their associated synonyms were searched using the Cochrane Library, Embase, PubMed, KISS, KMBASE, and KoreaMed databases. Academic information and portals of DBpia and RISS were also perused. Altogether, 340 papers were found, among which a total of 24 papers were selected according to the detailed criteria. Nine studies used hydroxyzine as monotherapy, and 10 studies compared its safety when hydroxyzine used as multitherapy. In addition, seven studies employed a drug regimen wherein hydroxyzine was one of the components. All these studies revealed that the adverse events specific to hydroxyzine usage were drowsiness and dryness of the mouth, and that there were respiratory complications due to a synergistic reaction of hydroxyzine. Although classified as a histamine blocker, hydroxyzine with its sedative, antiemetic, anticonvulsant, and anticholinergic properties is an oral sedative available without serious adverse events, If the proper dosage of the drug is used and its synergistic effects with other drugs are ascertained in the route of administration.

• CELLMED
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• v.12 no.3
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• pp.14.1-14.2
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• 2022

Currently, a 70-year-old woman started suffering from S.I joint pain from 1973 and had severe pain in the S.I joint, wrist, and elbow from 1975 to 1977, and was diagnosed with spinal tuberculosis at a general hospital. From 1978 to 1987, she suffered from chronic fatigue and insomnia, and since January 1, 1988, she was unable to get up while lying down, suffering from whole body joint, muscle pain, and fibromyalgia. In May 1989, she was also diagnosed with ankylosing spondylitis through genetic testing at the Catholic St. Mary's Hospital Rheumatology Department in Korea, and was treated with sulfasalazine, analgesic, and immunosuppressant, methotrexate, for 12 years until 1999, but none of the drugs eliminated the pain. She was hospitalized and discharged repeatedly, and continued to receive salt water poultice and exercise therapy at home, but was unable to move at all. In 2000, after biologic treatment with Remicade injection (Remsima®), she was able to walk and move, and after that, she was continuously prescribed biologics. From 2015 to 2019, Enbrel® (Etanercept) injection was prescribed once a week, but the symptoms such as severe pain (joint and muscle, fibromyalgia), scleroderma, Sjogren's syndrome (dryness of eyes, nose and mouth), difficulty swallowing, chronic fatigue, and stiff body appeared. Around January 2018, hepatic indicators were high and lymphocytes became enlarged. However, most serious injuries were highly improved after the OCNT combination therapy using active phytonutrients, anthocyanin-fucoidan nanocomplex. Therefore, for patients with such experiences, OCNT treatment is proposed as an alternative.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.17 no.6
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• pp.537-545
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• 2016

This research examined the oral environmental factors to identify the risk factors for oral bacteria detection. This study comprised of 60 office workers aged between 20 and 65 years, and was performed from January 15 to February 28, 2015. The study variables measured were the stimulated and unstimulated salivary flow rates, salivary buffering, saliva pH, dry mouth at the dorsum of the tongue and the sublingual region, halitosis, and the degree of tongue-coating as oral environmental factors. To identify the presence of oral bacteria, pathogens were detected by extracting the gDNA of the resting salivary flow rate. The risk of S.mutans detection was 15 times higher with smokers, 1.3~1.6 times higher when the resting or stimulated salivary flow rate was reduced by 1 mm. The risk of P.intermedia detection was 13 times higher in smokers, 4.3 times higher as the severity of oral dryness was lowered, and 4 times higher for adults with a tongue coating than those without. In addition, the risk of detecting TM7 was 5.5 times higher as sublingual dryness was decreased by 1mm. The oral bacterial count will be reduced considerably by smoking cessation education and habits that facilitate a salivary flow rate. Furthermore, adults with good and well-managed dental hygiene are anticipated to have less oral bacteria and fewer dental diseases.

• Journal of dental hygiene science
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• v.13 no.2
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• pp.142-150
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• 2013

The aim of this study was to analyze the factors related to self-reported halitosis. This study performed a questionnaire survey, targeting at 450 adults who lived in Seoul and Gyeonggi area. Main results of this study were as followings. Relationships between socio-demographic characteristics and halitosis showed no significant difference. Relationships between subjective oral health and halitosis, the groups that were treated dental prosthesis, aware of periodontal disease and dry mouth symptoms reported more halitosis (p<0.05). The group that brushed teeth less than twice a day, did not brush teeth after having a snack, and had frequent sweet treat reported more halitosis (p<0.05). The group that more experienced limitation, discomfort, discomfort reported more halitosis (p<0.05). Based on the results derived as above, the self-reported halitosis was shown to be related to periodontal disease, dry mouth, oral hygiene care and quality of life. Therefore, it is considered that preventing periodontal disease and oral dryness as well as reinforcing the oral hygiene care will contribute to prevention of halitosis and enhancement of quality of life.

• Journal of dental hygiene science
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• v.12 no.2
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• pp.171-179
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• 2012

The aim of this study was to analyze the factors related to whole saliva flow and the xerostomia for the ground use of the materials in developing oral health improvement program and life quality improvement program. So, this study performed a questionnaire survey, targeting at 160 adults, older than 40 years, living in Gyeonggi and Incheon provinces from January to February 2011 and measured unstimulated salivary flow rate and stimulated salivary flow rate. The results are as followings. The group of participants who took gums and candies to relieve oral dryness had low stimulated whole saliva flow. The group of participants who graduated from middle schools, who separated by death, who were not healthy with menopause, and who recognized periodontal disease symptoms and tongue burning sensation recognized more symptoms of dry mouth than others. In addition, the group of participants who were not satisfied with life so much, who couldn't feel the meaning of life, and who recognized negative feelings frequently recognized symptoms of dry mouth more. Women, the group of participants who graduated from middle schools, who suffered from depressive symptoms, and who recognized halitosis had low unstimulated whole saliva flow. The group of participants who graduated from middle schools, who were not satisfied with life so much, who couldn't feel the meaning of life, and who were not satisfied with themselves had low stimulated saliva flow.