• 제목/요약/키워드: Motor cortex

검색결과 218건 처리시간 0.041초

다리에 힘이 없는 환자에서 효과적인 운동 유발전위 파형 측정에 대한 고찰 (Effective Motor Evoked Potential Waveforms in Patients with Lower Extremity Weakness)

  • 임성혁;박상구;한형태
    • 대한임상검사과학회지
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    • 제48권1호
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    • pp.41-48
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    • 2016
  • Motor evoked potential of spinal surgery is known to cause damage due to the movement path of the continuous scan operation and surgery can be performed with minimized disability after surgery. However, if it is not at all formed at the wave motion evoked potential can occur during surgery and, in some cases the size of the waveform to be measured is very small and intermittent. In this case, the surgery cannot provide information about whether there is neurological damage. Increased intensity of the wave-induced motion of the dislocation does not occur if it appears in a very small amplitude stimulus, but changing the inspection area that electrical stimulation of the waveform changes could not be found. However, stimulation of a wide area in the cerebral cortex was found to occur with a waveform in the patients who underwent examination. Through this study, we propose a useful motor evoked potential test. From November to December 2015 three spine surgery patients visited Samsung Medical Center as neurosurgery patients with omission discomfort, gait disturbance, and no symptom of strength before surgery. In spine surgery patients with motor grade weakness, when motor evoked potential waveform has not been measured, in examination of the site of electrical stimulation of the cerebral cortex from entering the C3+C5/C4+C6 or C3+C1/C4+C2 if by the activity of more motor neuron unit, it was found that the waveform is better formed.

대뇌 피질 경색으로 인한 하지 단마비 환자 한방치험 2례 (2 Cases of Lower Limb Monoplegia due to Brain Cortical Infarction)

  • 신정애;손동혁;유경숙;이진구;이영구
    • 대한한방내과학회지
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    • 제22권2호
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    • pp.263-269
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    • 2001
  • Monoplegia is the paralysis of either the upper or lower limb. Monoplegia is commonly caused by an injury to the cerebral cortex; it is rarely caused by an injury to the internal capsule, brain stem, or spinal cord. Most cerebral cortex is derived from the occlusion of a brain cortex blood vessel due to thrombus or embolus. According to motor homunculus, lower limb monoplegia occurs from limited damage to the most upper part of the primary motor area(Brodmann's area 4, located in precentral gyrus). Clinically, lower limb monoplegia due to brain cortical infarction is commonly misunderstood as monoplegia due to spinal injury because the lesion is situated at the most upper part of precentral gyrus. We had many difficulties in finding lesion on brain CT, but we diagnosed two patients correctly by using an MRI, who have lower limb monoplegia due to brain cortical infarction oriental treatment.

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정신분열증에서 감각운동피질의 기능적 비대칭성의 장애: 기능적 자기공명영상을 이용한 연구 (Disturbed Functional Asymmetry of Sensorimotor Cortex in Schizophrenia: A Study with Functional Magnetic Resonance Imaging)

  • 안국진;채정호;김태;김의녕;이재문;최규호;한성태
    • Investigative Magnetic Resonance Imaging
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    • 제4권1호
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    • pp.52-57
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    • 2000
  • 목적: 기능적 자기공명영상을 이용하여 정신분열증 환자에서 운동자극에 의한 뇌 피질의 반응양상을 정상인과 비교하여 알아보고자 하였다. 대상 및 방법: 9 명의 오른손잡이 정신분열증 환자와 정신과학적으로 이상이 없는 6 명의 건강한 오른손잡이 자원자를 대조군으로 하였다. EPI 기법을 이용하여 한 절편 당 120 개의 연속영상 중 3 번의 휴식기와 활성화 시기를 반복하여 전체 4개의 절편에서 총 480개의 영상들을 얻었으며 오른손 운동을 운동자극으로 사용하였다. 영상 후 처리는 교차상관(cross correlation)을 이용하였고 운동자극 시에 우세 대뇌반구를 결정하기 위해 편측화 지수(lateralization index)를 측정하여 환자와 정상인 사이에서 비교하였다. 결과: 정상군에서는 오른손 운동자극시 좌측 감각운동중추에서 우측에 비해 월등히 많은 활성화를 나타내어 높은 펀측화 지수를 보인 반면 정신분열증 환자군의 경우는 좌측 감각운동중추의 활성화는 상대적으로 감소하고 동측인 우측의 활성화가 증가하여 정상군에 비해 낮은 편측화 지수를 나타냈다. 한 명의 환자에서는 우측 감각운동중추가 좌측에 비해 높은 활성화를 보이는 경우도 있었다(역편측화 reversed lateralization) 결론: 정상인에서 관찰되는 좌-우 감각운동피질의 기능적 비대칭성이 정신분열증환자에서는 다른 양상으로 관찰되었다. 이는 이 질환에서 뇌 피질내 운동회로의 기능적 이상이 있음을 반영하는 소견이며, 앞으로 기능적 자기공명영상이 이 질환의 진단과 연구에 많은 도움을 줄 것으로 생각한다.

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Unsuspected Plasticity of Single Neurons after Connection of the Corticospinal Tract with Peripheral Nerves in Spinal Cord Lesions

  • Brunelli, Giorgio;Wild, Klaus von
    • Journal of Korean Neurosurgical Society
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    • 제46권1호
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    • pp.1-4
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    • 2009
  • Objective: To report an unsuspected adaptive plasticity of single upper motor neurons and of primary motor cortex found after microsurgical connection of the spinal cord with peripheral nerve via grafts in paraplegics and focussed discussion of the reviewed literature. Methods: The research aimed at making paraplegics walk again, after 20 years of experimental surgery in animals. Amongst other things, animal experiments demonstrated the alteration of the motor endplates receptors from cholinergic to glutamatergic induced by connection with upper motor neurons. The same paradigm was successfully performed in paraplegic humans. The nerve grafts were put into the ventral-lateral spinal tract randomly, with out possibility of choosing the axons coming from different areas of the motor cortex. Results: The patient became able to selectively activate the re-innervated muscles she wanted without concurrent activities of other muscles connected with the same cortical areas. Conclusion: Authors believe that unlike in nerve or tendon transfers, where the whole cortical area corresponding to the transfer changes its function a phenomenon that we call "brain plasticity by areas". in our paradigm due to the direct connection of upper motor neurons with different peripheral nerves and muscles via nerve grafts motor learning occurs based on adaptive neuronal plasticity so that simultaneous contractions of other muscles are prevented. We propose to call it adaptive functional "plasticity by single neurons". We speculate that this phenomenon is due to the simultaneous activation of neurons spread in different cortical areas for a given specific movement, whilst the other neurons of the same areas connected with peripheral nerves of different muscles are not activated at the same time. Why different neurons of the same area fire at different times according to different voluntary demands remains to be discovered. We are committed to solve this enigma hereafter.

Acupuncture stimulation for motor cortex activities: Evidence from 3T functional MRI study

  • 최보영;전신수;유승식;최기순;박상동;임은철;정성택;이형구;서태석
    • 한국의학물리학회:학술대회논문집
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    • 한국의학물리학회 2003년도 제27회 추계학술대회
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    • pp.75-75
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    • 2003
  • Purpose: To investigate whether or not acupuncture of GB34 produces a significant response of the modulation of somatomotor areas by functional magnetic resonance imaging (fMRI) study. Methods: The acupoint, GB34, located in the back of the knee, is known to be effective in recovering motor function after stroke. Using 3T MRI scanner, functional MR imaging of the whole brain was performed in 12 normal healthy subjects during two stimulation paradigms; acupuncture manipulation on GB 34 and sham points. This study investigates the activation of the motor cortex elicited by a soft and an intensified stimulation of GB 34. Three different paradigms were carried out to detect any possible modulation of the Blood Oxygenation Level Dependent (BOLD) response in the somatomortor area to motor stimulation through acupuncture. Results: Group analysis from seven individuals showed that bilateral sensorimotor areas (BA 3,4,6 and 7) showed stimulation related BOLD signal contrast of approximately 6% whereas very few areas were activated when sham stimulation is given. Conclusions: The present study shows that acupuncture fMRI study can be safely conducted in 3T MRI environment, and acupuncture stimulation in GB34 modulates the cortical activities of the soma- to motor area in human. The present findings may shed light on the CNS mechanism of motor function by acupuncture and form a basis for future investigations of motor modulation circuits in the stroke patients. Acknowledgement: This study was supported by a grant of the Mid and Long Term Nuclear RID Plan Program, Ministry of Science and Technology, Republic of Korea.

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기능적 자기공명영상을 이용한 구심성 및 원심성 근 수축에 따른 뇌 활성도 분석 (Comparison of Cortical Activation between Concentric and Eccentric Exercise: A Pilot fMRI Study)

  • 김중선;김중휘;박민규;박지원
    • The Journal of Korean Physical Therapy
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    • 제22권2호
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    • pp.25-30
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    • 2010
  • Purpose: Behavior and movement are accomplished by voluntary contractions of skeletal muscles. There are three types of muscle contractions: concentric, isometric and eccentric. The aim of our study was to determine whether there is a difference in the cortical activation pattern between concentric contraction and eccentric contraction of the wrist extensor muscle. Methods: Four healthy right-handed volunteers without any previous history of physical or neurological illness were recruited. fMRI scanning was done during 4 repeated blocks of concentric and eccentric exercise of the wrist joint. Subjects exercised for 12 seconds and then rested for 12 seconds before beginning the second set of exercises. To determine the excitability of cortical neurons during exercise, voxel count and intensity index were analyzed. Results: For right hand movements, when concentric contractions of the right wrist were done, only the left primary motor area was activated. In contrast, during eccentric contraction, both the primary motor area and secondary motor area were activated. For left hand movements, both concentric and eccentric contractions induced only the supplementary motor cortex and the contralateral primary motor cortex. Conclusion: During eccentric contractions, both the primary motor area and secondary motor area are activated in ipsilateral and contralateral brain areas. Thus, eccentric contractions require more complex and difficult movements than concentric contractions do.

Targeting motor and cognitive networks with multichannel transcranial direct current stimulation along with peripheral stimulation in a subacute stroke survivor: single case study

  • Midha, Divya;Arumugam, Narkeesh
    • Physical Therapy Rehabilitation Science
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    • 제9권4호
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    • pp.318-323
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    • 2020
  • Objective: Reacquisition of motor functions following stroke depends on interhemispheric neural connections. The intervention highlighted in the present case is an insight for augmenting motor recovery by stimulating the lesioned area and adjacent areas governing the motor behaviour of an individual. The purpose of this study was to determine the changes in the motor and cognitive outcomes through multi target stimulation of cortical areas by application of multichannel transcranial direct current stimulation (M-tDCS) in a stroke survivor. Design: A case report. Methods: The patient was a participant of a trial registered with the clinical trial registry of India (CTRI/2020/01/022998). The patient was intervened with M-tDCS over the left primary motor cortex i.e. C3 point and left dorsolateral prefrontal cortex i.e. F3 point with 0.5-2 mA intensity for the period of 20 minutes. SaeboFlex-assisted task-oriented training, functional electrical stimulation over the lower extremity (LE) to elicit dorsiflexion at the ankle and eversion of the foot, and conventional physiotherapy rehabilitation including a tailored exercise program were performed. Outcome assessment was done using the Fugl-Meyer assessment scale (FMA) for the upper and lower extremity (UE and LE), Montreal Cognitive Assessment (MOCA), Wisconsin Gait Scale (WGS) and the Stroke Specific Quality of Life (SSQOL) measures. Assessment was taken at Day 0, 15 and 30 post intervention. Results: Improvement was observed in all the outcome measures i.e FMA (UE and LE), MOCA, SSQOL and WGS across the span of 4 weeks. Conclusions: M-tDCS induced improvement in motor functions of the UE and LE, gait parameters and cognitive functions of the patient.

동적인지 맵을 이용한 뇌 정보 처리 시스템의 감정 평가 알고리즘 (Emotion Evaluation algorithm of Brain Information System using Dynamic Genitive Maps)

  • 홍인택;김성주;서재용;김용택;전홍태
    • 대한전자공학회:학술대회논문집
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    • 대한전자공학회 2003년도 하계종합학술대회 논문집 Ⅲ
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    • pp.1243-1246
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    • 2003
  • It is known that structure of Human's brain information system is controlled by cerebral cortex mainly. Cerebral cortex is divided by sensory area, motor area and associated area largely. Sensory area takes part in information from environment and motor area is actuation by decision as associated area determined. It is possible to copy brain information system by input-output pattern. but there is difficulty in modeling of memorizing new information. Such action is performed by Limbic Lobe and Papez circuit which is controlled by intrinsic emotion. So we need of definition of emotion's role in decision. In this paper, we define roles of emotion in intrinsic decision using Dynamic Cognitive Maps(DCMs). The emotion is evaluated by outside information then intrinsic decision performed as how much emotion variated. The dynamic cognitive maps take part in emotion evaluating process.

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Partial Least Squares-discriminant Analysis for the Prediction of Hemodynamic Changes Using Near Infrared Spectroscopy

  • Seo, Youngwook;Lee, Seungduk;Koh, Dalkwon;Kim, Beop-Min
    • Journal of the Optical Society of Korea
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    • 제16권1호
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    • pp.57-62
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    • 2012
  • Using continuous wave near-infrared spectroscopy, we measured time-resolved concentration changes of oxy-hemoglobin and deoxy-hemoglobin from the primary motor cortex following finger tapping tasks. These data were processed using partial least squares-discriminant analysis (PLS-DA) to develop a prediction model for a brain-computer interface. The tasks were composed of a series of finger tapping for 15 sec and relaxation for 45 sec. The location of the motor cortex was confirmed by the anti-phasic behavior of the oxy- and deoxy-hemoglobin changes. The results were compared with those obtained using the hidden Markov model (HMM) which has been known to produce the best prediction model. Our data imply that PLS-DA makes better judgments in determining the onset of the events than HMM.

뇌-기계접속 된 동물과 사람사이의 실시간 인터넷게임 (A Real time Internet Game Played with a Brain-Computer Interfaced Animal)

  • 이현주;김대환;랑이란;한승훈;김용범;이근수;이은주;송창근;신형철
    • 한국HCI학회:학술대회논문집
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    • 한국HCI학회 2007년도 학술대회 1부
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    • pp.780-783
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    • 2007
  • A Many studies have been made on the prediction of human voluntary movement intention in real-time based on invasive or non-invasive methods to help severely motor-disabled persons by offering some abilities of motor controls and communications. In the present study, we have developed an internet game driven by and/or linked to a brain-computer interface (BCI) system. Activities of two single neuronal units recorded from either hippocampus or prefrontal cortex of SD rats were used in real time to control two-dimensional movements of a robot, or a game object.

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