• The Korean Journal of Physiology
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• 제30권1호
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• pp.117-124
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• 1996

This study evaluated the hypothesis that motoneuron collaterals modulate the excitability of ventral spinocerebellar tract neurons. In acute cats, 128 ventral cerebellar tract cells were studied extracellularly to determine the effects of ventral root stimuli. The majority of the cells responded to ventral root stimulation with either short or long latency increases in spike discharge. In many cells with sufficient spontaneous activity ventral root stimulation also evoked a long lasting reduction in activity. In preparations with the dorsal root ganglion removed VSCT neurons had similar response properties. In some cells contralateral ventral root stimulation also evoked excitatory responses. These findings indicate the VSCT can provide the cerebellum with information regarding activity in the final output neurons of the motor system, the alpha motoneurons.

• Biomolecules & Therapeutics
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• 제10권4호
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• pp.258-267
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• 2002

In this study the general pharmacological profiles of AS6 on the central nervous system, cardiovascular and the other organs were investigated. The dosages given were 0, 250, 500 and 1000 mg/kg and drugs were orally administered. The animals used for this study were mice, rats and guinea pigs. Significant increases (p<0.01) in the charcoal transport capacity were observed at the high dose of 1000 mg/kg and significant increases in retardation of pain threshold were observed in the test using acetic acid in all dosed animals. However, AS6 showed no noticeable effects on general behavior, motor coordination, spontaneous locomotor activity, hexobarbital-induced sleep time, body temperature, analgesic activity in the test using hot plate method and anticonvulsant activity. Furthermore no noticeable effects were observed in cardiovascular functions in the isolated rat heart, contraction and relaxation of the smooth muscle in the isolated guinea ileum, gastric secretion and renal function.

• Journal of Preventive Medicine and Public Health
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• 제46권sup1호
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• pp.12-21
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• 2013

Several epidemiological studies have shown that exercise (EX) and physical activity (PA) can prevent or delay the onset of different mental disorders, and have therapeutic benefits when used as sole or adjunct treatment in mental disorders. This review summarizes studies that used EX interventions in patients with anxiety, affective, eating, and substance use disorders, as well as schizophrenia and dementia/mild cognitive impairment. Despite several decades of clinical evidence with EX interventions, controlled studies are sparse in most disorder groups. Preliminary evidence suggests that PA/EX can induce improvements in physical, subjective and disorder-specific clinical outcomes. Potential mechanisms of action are discussed, as well as implications for psychiatric research and practice.

• 한국정밀공학회지
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• 제28권9호
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• pp.1110-1118
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• 2011

The recent power add-on drive wheelchairs (PADWs) provide greater physical activity and easier transportability and may be an excellent alternative for the typical manual and powered wheelchairs. The driving system consists of a motor and a motor driver is the most important component of the PADW In this paper, design, implementation, and testing of a driving system for a PADW are presented. To design the output power and torque for the driving system, the equation of motion has been investigated. The motor and driver were fabricated with precise machining and assembled to implement our prototype driving system. The dynamometer test has been carried out using the prototype in order to examine the torque of the system. The experimental results demonstrates that the designed driving system can provide enough output power and efficiency for utilization in a PADW.

• 한국수소및신에너지학회논문집
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• 제26권4호
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• pp.318-323
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• 2015

For commercialization of fuel cell electric vehicles, one of the key objectives is to improve durability of MEA and electrocatalysts. Regarding electrocatalysts, the major issue is to reduce carbon corrosion and dissolution of Pt caused by harsh conditions, for example, SU/SD (Start-up/Shut-down). In this research, OER (Oxygen Evolution Reaction) catalyst has been developed improvement of durability. A modified polyol process is developed by controlling the pH of the solvent to synthesize the PtIr nanocatalysts on carbon supports. Each performance of the MEAs applying PtIr and Pt are equivalent because PtIrnanocatalysts have both ORR and OER activity. Breadboard test for catalyst durability in harsh conditions and high potentialsis found that the MEA applying PtIrnanocatalysts durability is improved more than the MEA applying Pt nanocatalysts.

• 대한전기학회논문지:전기물성ㆍ응용부문C
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• 제55권4호
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• pp.178-182
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• 2006

Five model coils of 6.6 kV motor were manufactured with several defects. These stator coils have artificial defects such as void of groundwall insulation, removal of semi-conductive coating and damage of strand insulation. Epoxy-mica coupler(80 pF) was connected to five model coil terminals. The voltage applied to the coils was 3.81 kV, 4.76 kV, 6.0 kV and 6.6 kV, respectively. Partial discharge(PD) tests performed in the laboratory and shield room. Digital PD detector(PDD) and turbine generator analyzer(TGA) were used to measure PD activity. TGA summarizes each plot with two quantities such as the normalized quantity number(NQN) and the peak PD magnitude(Qm). The PD levels in pC were measured with PDD. PD patterns of model coils were indicated the internal and slot discharges. PD patterns are consistent with the result of measurement using PDD and TGA instruments. AC breakdown test was performed on five model coils in order to confirm the result of PD measurements. All the failures were located in a line-end coil at the exit from the core slot.

• 대한전기학회:학술대회논문집
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• 대한전기학회 2003년도 하계학술대회 논문집 C
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• pp.1828-1830
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• 2003

Partial discharge(PD) tests are used to evaluate the insulation condition of stator windings in two 4.16kV and three 6.6kV motors. These tests were conducted using a conventional partial discharge detector(PDD) and turbine generator analyzer(TGA). Off-line PD measurements were performed on five high voltage motors. PD magnitudes ranged from 1000 pC to 5400 pC at the normal line-to-ground voltage. Five high voltage motors have been equipped with 80pF epoxy-mica coupler on the motor terminal box. The PD pulse from sensors were measured with the TGA instrument. TGA summarizes each plot with two Quantities such as the peak PD magnitude(Qm) and the total PD activity(NQN). The defect mechanisms of high voltage motor can be associated with PD patterns such as internal, slot and conductor surface discharges. The PDD and TGA test results of No. 4 motor showed that internal discharge was detected in voids of the groundwall insulation.

• 대한물리의학회지
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• 제5권2호
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• pp.265-272
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• 2010

Purpose : This study was investigated the effect of electroacupuncture stimulation on the change of blood biochemical components in the rat spinal cord injury(SCI) damaged by the 6-hydroxydopamine. Methods : SCI model rats were damaged in L1-L2 injected with 6-hydroxydopamine. The thirty Sprague-Dawley adult male rats were randomly divided into normal group, control group and electroacupuncture group. Experimental groups were applied as electroacupuncture(Es-160, ITO, Japan) for 15minutes during the low frequency(2 Hz) stimulation to zusanli. The enzyme concentration levels analysis of the hematological changes were measured of Glutamate Oxaloacetate Transaminase(GOT), Glutamate Pyruvate Transaminase(GPT), Lactate dehydrogenase(LDH) and motor function recovery change was evaluated by the rota-rod test. Results : This study were as follow : The concentration of GOT, LDH in experimental group was lower than control group(p<.05). The experimental group showed increase of motor function recovery more in compared to control group(p<.05). Conclusion : The results of this study showed that electroacupuncture to zusanli point have an effect on functional recovery after the 6-hydroxydopamine induced SCI in rats.

• 재활복지
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• 제20권4호
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• pp.177-201
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• 2016

본 연구는 재활체육프로그램의 구성요인과 요소를 탐색하여 도출하고 각 요소 간의 상대적 중요도를 분석함으로써 재활체육프로그램의 체계적인 구성과 효율적 시행을 위한 토대를 마련함에 그 목적이 있다. 재활체육프로그램의 구성 요인과 요소를 도출하기 위하여 장애인을 대상으로 재활체육 및 장애인체육 관련 프로그램을 운영한 기관 단체 병원에 2년 이상 종사한 경험이 있는 지도자, 특수체육교사, 특수체육학계 전문가 20명을 대상으로 델파이기법(Delphi Technique)을 활용하여 3차에 걸쳐 설문을 진행하였다. 도출된 재활체육프로그램 구성요인들 간의 상대적 중요도를 도출하기 위해 의사결정 방식의 과학적 방법 중 하나 인 계층분석(Analytic Hierarchy Process: AHP)을 실시하였다. 연구결과 재활체육프로그램의 구성 요인으로 체력운동, 심리운동, 수중운동, 감각 지각운동, 보행운동, 운동기술 6개 요인과 21개의 하위요소로 도출되었다. 도출된 재활체육프로그램의 구성요인의 우선순위를 분석한 결과, 체력운동(33.2%), 수중운동(20.6%), 심리운동(15.1%), 감각 지각운동(11.7%), 보행운동( 10.8%), 운동기술(8.6%) 순으로 중요도가 나타났다. 또한 재활체육프로그램 구성 요인의 가중치가 부여된 상태에서 전체 요소 간 우선순위를 분석한 결과, 근력 및 근지구력운동이 23.4%의 가중치를 나타내어 가장 중요한 요소인 것으로 나타났으며, '명상'은 0.3%의 가중치를 나타내어 가장 낮은 중요 요소인 것으로 나타났다.

• Biomolecules & Therapeutics
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• 제12권2호
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• pp.114-121
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• 2004

This study was undertaken to evaluate the general pharmacological properties of CJ-11828, an amlodipine adipate, in experimental animals and in vitro system. CJ-11828 had no effects on general behavior, motor coordination, writhing syndromes, pentetrazol-induced chemoshock and electric shock in mice at dose levels of 3,10, anti 30 mg/kg, po. But there were decrease of body temperature, prolongation of sleeping time, and inhibition of intestinal activity in mice treated with CJ-11828 at doses of 10 and 30 mg/kg, po. CJ-11828 decreased the blood pressure in coscuous fog at the dose level of 2mg/kg, po, but it was expected as a result of pharmacological activity of CJ-11828. Any effect on respiratory system was not observed in conscious rat at doses of 3,10, and 30 mg/kg, po. The slight decrease in spontaneous motor activity was observed in mice treated with CJ-11828 at high dose, 30 mg/kg. In vitro experiments, CJ-11828 had no effect on agonists-induced contraction of isolated guinea pig ileum at 0.1, 1, and 10 ${\mu}$M. Based on these results, it was concluded that CJ-11828 had no pharmacological effect ill these studies even up to the 36-fold anticipated clinical dose, 3 mg/kg.