• Title/Summary/Keyword: Motif resource integration

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Implementation of Protein Motif Prediction System Using integrated Motif Resources (모티프 자원 통합을 이용한 단백질 모티프 예측 시스템 구현)

  • Lee, Bum-Ju;Choi, Eun-Sun;Ryu, Keun-Ho
    • The KIPS Transactions:PartD
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    • v.10D no.4
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    • pp.679-688
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    • 2003
  • Motif databases are used in the function and structure prediction of proteins which appear on new and rapid release of raw data from genome sequencing projects. Recently, the frequency of use about these databases increases continuously. However, existing motif databases were developed and extended independently and were integrated mainly by using a web-based cross-reference, thus these databases have a heterogeneous search result problem, a complex query process problem and a duplicate database entry handling problem. Therefore, in this paper, we suppose physical motif resource integration and describe the integrated search method about a family-based protein prediction for solving above these problems. Finally, we estimate our implementation of the motif integration database and prediction system for predicting protein motifs.

Implementation of Prototype for a Protein Motif Prediction and Update (단백질 모티프 예측 및 갱신 프로토 타입 구현)

  • Noh, Gi-Young;Kim, Wuon-Shik;Lee, Bum-Ju;Lee, Sang-Tae;Ryu, Keun-Ho
    • The KIPS Transactions:PartD
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    • v.11D no.4
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    • pp.845-854
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    • 2004
  • Motif databases are used in the function and structure prediction of proteins. The frequency of use about these databases increases continuously because of protein sequence data growth. Recently, many researches about motif resource integration are proceeding. However, existing motif databases were developed independently, thus these databases have a heterogeneous search result problem. Database intnegration for this problem resolution has a periodic update problem, a complex query process problem, a duplicate database entry handling problem and BML support problem. Therefore, in this paper, we suppose a database resource integration method for these problem resolution, describe periodically integrated database update method and XML transformation. finally, we estimate the implementation of our prototype and a case database.

Implementation of Integrated search method for Motif Resources (모티프 자원에 대한 통합 접근 검색 메소드 구현)

  • Trang Nguyen Thu;Lee Bum-Ju;Ryu Keun-Ho
    • Proceedings of the Korea Information Processing Society Conference
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    • 2006.05a
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    • pp.3-6
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    • 2006
  • Motif which is a recurrent feature shared by a significant segments from the proteins belonging to different families can be used to predict functional or structural properties of the protein, or to describe features common to biologically related proteins. Although there are many existed motif databases, they are unstandardized and built up by different methods. so it is difficult to get enough motif information when researches use motif databases for classification, prediction, etc. Using logical integration of biological based on cross-references between these databases is the common solution for information tracking through www. However, the problem such as the motif resource tracking method for making a united motif information page emerges from cross-reference. In this paper we propose the motif resource tracking method based on the existed motif databases for easy and comfortable interface better than in the case of using each motif database. The result which is given by this method is the review of necessary information about any motif in PROSITE database.

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