• Title/Summary/Keyword: Morphological Damage

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Morphological change of Mongolian gerbil testis and DNA damage of spermatocytes by irradiation (방사선 조사에 의한 몽고리안 저빌 고환의 형태 및 정모세포의 DNA 손상 변화)

  • 김진규;송치원;김무강;김봉희;천기정
    • Proceedings of the Korea Society of Environmental Toocicology Conference
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    • 2001.05a
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    • pp.120-120
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    • 2001
  • 방사선 조사는 생물체의 여러 장기에 큰 손상을 일으키며 생식기에도 큰 영향을 미치는 것으로 알려져 있다. 이중 숫컷의 고환내의 분화중인 정모세포는 매우 민감함을 나타내며 그 결과 방사선 조사 정도에 따라 정자의 이상 형태 및 정자수의 감소를 나타내어 무정자증까지 초래할 가능성이 있는 것으로 알려져 있다. 본 실험에는 8주된 Mongolian gerbil 숫컷을 사용하여 5Gy 및 10 Gy(선량률 : 1 Gy/분)를 조사하였으며 방사선 조사 바로 직후 및 7일에 고환을 채취하였다. (중략)

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Morphological Changes of Bones and Joints with Rheumatoid Arthritis and Osteoarthritis

  • Hong, Yun-Kyung;Javaregowda, Palaksha Kanive;Lee, Sang-Kil;Lee, Sang-Rae;Chang, Kyu-Tae;Hong, Yong-Geun
    • Reproductive and Developmental Biology
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    • v.35 no.2
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    • pp.143-149
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    • 2011
  • Arthritis is a common disease in aged people, and is clinically divided into rheumatoid arthritis (RA) and osteoarthritis (OA). Although common symptoms such as pain are present, the underlying pathological mechanisms are slightly different. Therefore, the objectives of the present study were to compare joint damage induced by RA and OA by analyzing the major morphological and molecular differences, and to propose a suitable therapeutic intervention based on the pathophysiological conditions of bones and joints. For the RA animal model, 8-week-old DBA1/J mice were immunized with bovine type II collagen emulsified in complete Freund's adjuvant (CFA). Normal C57BL/6 mice (over 2 years of age) were used for OA. The clinical arthritis score was calculated using a subjective scoring system, and paw thicknesses were measured using calipers. The serum TNF ${\alpha}$ level was analyzed using an ELISA kit. Micro-CT was used to identify pathological characteristics and morphological changes. In collagen-induced RA mice, there were increased ankle joint volumes and clinical scores (p<0.01). The concentration of TNF ${\alpha}$ was significantly increased from 3 to 7 weeks after immunization. Micro-CT images showed trabecular bone destruction, pannus formation, and subchondral region destruction in RA mice. OA among aged mice showed narrowed joint spaces and breakdown of articular cartilage. This study suggests that a careful therapeutic intervention between RA and OA is required, and it should be based on morphological alteration of bone and joint.

Nano-Scale Surface Observation of Cyclically Deformed Copper and Cu-Al Single Crystals (반복변형된 동 및 동알루미늄 단결정 표면형상의 나노-스케일 관찰)

  • ;;Hitoshii ISHII
    • Proceedings of the Korean Society of Tribologists and Lubrication Engineers Conference
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    • 1999.06a
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    • pp.67-72
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    • 1999
  • Scanning probe Microscope(SPM) such as Scanning Tunneling Microscope(STM) and Atomic Force Microscope(AFM) was shown to be the powerful tool for nano-scale characterization of material surfaces Using this technique, surface morphology of the cyclically deformed Cu or Cu-Al single crystal was observed. The surface became proportionately rough as the number of cycles increased, but after some number of cycles no further change was observed. Slip steps with the heights of 100 to 200 nm and the widths of 1000 to 2000 nm were prevailing at the stage. The slipped distance of one slip system at the surface was not uniform. and formation of the extrusions or intrusions was assumed to occur such place. By comparing the morphological change caused by crystallographic orientation, strain amplitude, number of cycles or stacking fault energy, some interesting results which help to clarify the basic mechanism of fatigue damage were obtained. Furthermore, applicability of the scanning tunneling microscopy to fatigue damage is discussed.

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Effects of bleaching time and hydrogen peroxide concentration on hair damage (탈색시간과 과산화수소 농도에 의한 모발의 손상)

  • Kim, Chung-Wun;Chun, Hong-Sung
    • Korean Journal of Human Ecology
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    • v.14 no.3
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    • pp.433-439
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    • 2005
  • In this study, we investigated the morphological and physical changes of hair after bleaching treatments with different concentration of hydrogen peroxide in bleaching agent (3, 6, 9, or 12%) and various treatment time (10, 30, or 60 minutes). Tresses of virgin black hair were bleached using a commercial ammonium persulfate-hydrogen peroxide solution. The tensile strength of virgin hair treated with a bleaching agent depended on the concentration of hydrogen peroxide and the treatment time. As the concentration of hydrogen peroxide in bleaching agent went high and the treatment time increased, the tensile strength of the hair increased but the extension degree decreased. The virgin hairs which were not treated by bleaching agent showed morphologically healthy cuticle, whereas the bleached hairs showed swelled and damaged cuticle patterns. The swelling of the hair and the breaks of the cuticles increased positively by the concentration of hydrogen peroxide and the treatment time. These results suggest that exposure to more concentrated hydrogen peroxide with other bleaching components may lead to more severe hair damage.

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A study on Histologically Change of the Skin and Liver in Skin Burn (피부화상에 의한 피부 및 간의 조직학적 변화에 관한 연구)

  • Kim, Han-Soo;Kim, Sang-Soo;Kim, Yong-Kwon
    • Journal of Korean Physical Therapy Science
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    • v.8 no.1
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    • pp.923-934
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    • 2001
  • In order to investigate a pathogenesis of liver damage induced by skin burn, thermal injury was induced by scald burn on entirely dorsal surface in rats (total body surface area 30%) except for inhalated injury. At 5 and 24 h after scald bum, biochemical assay and morphological changes in skin tissue, serum and liver tissue were examined. The effects of bum injury on the levels of glutathione, lipid peroxide and on the activities of oxygen free radical generating and scavenging enzymes have been determined in association with observing of histologic and ultrastructural changes, measuring the protein concentration in plasma, and counting the number of intravascular polymorphonuclear leukocytes. The activity of xanthine oxidase, an enzyme of oxygen free radical generating system. was elevated (p<0.01) in serum, but not in skin and in liver tissue. Futhermore, thermal injury decreased not only the protein concentration in plasma but also the number of leukocytes, that indicates induction of edema formation with protein exudation and inflammation by neutrophil infiltration into the internal organs. These data suggest that acute dermal scald burn injury leads to liver damage, that is related to elevation of xanthine oxidase activity in serum. Xanthine oxidase may be a key role in the pathogenesis of liver damage induced by skin burn.

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Effect of Root Amount on Wind Damage in Rice

  • Chang, Jae-Ki;Yeo, Un-Sang;Oh, Byong-Geun;Kang, Jung-Hoon;Yang, Sae-Jun;Kim, Soon-Chul
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.48 no.2
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    • pp.108-112
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    • 2003
  • Foehn damage on rice plant is one of the important abiotic stresses in eastern costal area of Korea. To know the relationship between foehn impact and morphological traits of rice, wind tunnel method was used with 106 rice cultivars. Less influencing traits on foehn were short panicle, large panicle number per hill, thin panicle neck, and the flag leaf of narrow, short and thick. Leaf pubescence reduced the impact on foehn. 'Naepungbyeo' belong-ed to foehn tolerant varietal group, while 'Ansanbyeo' belonged to the opposite group. Three levels of root cutting treatment with two rice cultivars were conducted to evaluate the foehn impact using wind tunnel. The severity of wind damages was followed the sigmoidal curve duration of wind tunnel treatment were prolonged. Different responses of root cutting to wind tunnel treatment could be used to evaluate the severity of the foehn impact. 'Naepungbyeo' was one of the less implausible cultivars on foehn. 'Nae-pungbyeo' showed tolerant response to wind under 21% root removing treat-ment (20㎝ root cutting), however 'Ansanbyeo' was wilted under the same treatment. In case of 35 % root removing treatment(10㎝ root cutting), both rice cultivars failed to alive against foehn wind.

DCT and DWT based Damaged Weather Radar Image Retrieval (DCT 및 DWT 기반의 손상된 기상레이더 영상 복원 기법)

  • Jang, Bong-Joo;Lim, Sanghun;Kim, Won;Noh, Huiseong
    • Journal of Korea Multimedia Society
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    • v.20 no.2
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    • pp.153-162
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    • 2017
  • Today, weather radar is used as a key tool for modern high-tech weather observations and forecasts, along with a wide variety of ground gauges and weather satellites. In this paper, we propose a frequency transform based weather radar image processing technique to improve the weather radar image damaged by beam blocking and clutter removal in order to minimize the uncertainty of the weather radar observation. In the proposed method, DCT based mean energy correction is performed to improve damage caused by beam shielding, and DWT based morphological image processing and high frequency cancellation are performed to improve damage caused by clutter removal. Experimental results show that the application of the proposed method to the damaged original weather radar image improves the quality of weather radar image adaptively to the weather echo feature around the damaged area. In addition, radar QPE calculated from the improved weather radar image was also qualitatively confirmed to be improved by the damage. In the future, we will develop quantitative evaluation scales through continuous research and develop an improved algorithm of the proposed method through numerical comparison.

A Study of Effects of Fermented Green Tea Extract-based Treatment on Hair (발효녹차액을 이용한 모발의 트리트먼트 효과)

  • Park, Kwi Hee;Lim, Sun Nye
    • Textile Coloration and Finishing
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    • v.26 no.4
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    • pp.353-362
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    • 2014
  • This study attempted to determine the effects of fermented green tea extracts on hair by using them in a perm. For this, hair is bleached, and then the fermented green tea extracts and water were supplied to the hair using a mist sprayer. Then the hair was permed, and hair damage was tested. Regarding hair moisture levels and wave formation, specifically, the morphological changes of hair were investigated with the Scanning Electron Microscope(SEM). The study results found the following. In terms of wave formation, the fermented green tea extract-based perm was much better than the general perm. In addition, hair bleaching was more serious in the latter. According to analysis on hair moisture using SEM, hair damage was more prevalent in the general perm as well. Therefore, it was confirmed that green tea extract-based perms cause less damage to the cuticle. In other words, the potential of fermented green tea extracts as a hair cosmetics material was discovered. Furthermore, it appears that the study results contribute to the development of low-irritating scalp and hair care products using the anti-inflammatory and antimicrobial properties of the fermented green tea extracts.

Spectroscopic Evaluation on the Chemical Damage of Hair by Hydrogen Peroxide (과산화수소에 의한 모발의 화학적 손상에 관한 분광학적 평가)

  • Ha, Byung-Jo
    • Applied Chemistry for Engineering
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    • v.22 no.5
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    • pp.579-581
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    • 2011
  • Spectroscopic evaluation of hair chemical damage was performed by SEM/EDS, CLSM, and FT-IR spectroscopy. In SEM/EDS, hydrogen peroxide treated hair showed the loose packing of surface scales, lower ratio of sulfur element and higher ratio of oxygen atom. In the optical single section by using CLSM, high fluorescent intensity appeared in untreated hair. However, in case of treated hair, low fluorescent intensity appeared. This results the aromatic amino acids which can be autofluorescent were more abundant than bleached hair. FT-IR spectra showed that cysteic acid band intensity was increased by performing the bleaching treatments. These results indicate that the oxidative damage cleaves the S-S bond and results in the lower working force of hair fiber.

Abusive Detection Using Bidirectional Long Short-Term Memory Networks (양방향 장단기 메모리 신경망을 이용한 욕설 검출)

  • Na, In-Seop;Lee, Sin-Woo;Lee, Jae-Hak;Koh, Jin-Gwang
    • The Journal of Bigdata
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    • v.4 no.2
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    • pp.35-45
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    • 2019
  • Recently, the damage with social cost of malicious comments is increasing. In addition to the news of talent committing suicide through the effects of malicious comments. The damage to malicious comments including abusive language and slang is increasing and spreading in various type and forms throughout society. In this paper, we propose a technique for detecting abusive language using a bi-directional long short-term memory neural network model. We collected comments on the web through the web crawler and processed the stopwords on unused words such as English Alphabet or special characters. For the stopwords processed comments, the bidirectional long short-term memory neural network model considering the front word and back word of sentences was used to determine and detect abusive language. In order to use the bi-directional long short-term memory neural network, the detected comments were subjected to morphological analysis and vectorization, and each word was labeled with abusive language. Experimental results showed a performance of 88.79% for a total of 9,288 comments screened and collected.

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