• Archives of Pharmacal Research
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• v.22 no.1
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• pp.9-12
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• 1999

A new glycoprotein was purified from the aqueous methanolic extract of the root bark of Morus alba which has been used as a component of antidiabetic remedy in Oriental Medicine. SDS-PAGE result shows that the molecular weight of the glycoprotein was approximately 20 kDa. This new glycoprotein was named as Moran 20K. The protein lowered blood glucose level in streptozotocin-induced hyperglycemic mice model and it also increased the glucose transport in cultured epididymis fat cells. The amino acid composition of the protein was analyzed, and the protein contained above 20% serine and cysteine such as insulin. The actual molecular weight of the protein was determined as 21.858 Da by MALDI-TOF mass spectroscopy.

• Journal of Life Science
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• v.24 no.8
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• pp.813-819
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• 2014

The spatial distribution of geographical distances at five natural populations of Camellia japonica in Busan, Korea was studied. The four plots (Mollundae, Gadeok-do, Du-do, and Jwiseum) of C. japonica were uniformly distributed in the forest community and only one plot (Amnam-dong) was aggregately distributed in the forest community. Morisita index is related to the patchiness index showed that the plot $20m{\times}50m$ had an overly steep slope when the area was larger than $20m{\times}20m$, which indicated that the degree of aggregation increased significantly with increasing quadrat sizes, while the patchiness indices did not change from the plot $5m{\times}10m$ to $10m{\times}10m$. The spatial structure was quantified by Moran's I, a coefficient of spatial autocorrelation. Ten of the significant values (76.9%) were positive, indicating similarity among individuals in the first 4 distance classes (80 m), i.e., pairs of individuals with dissimilarity characteristics can separate by more than 100 m.

• Journal of Korean Society of Forest Science
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• v.106 no.3
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• pp.310-319
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• 2017

This study categorized the damaged trees by Supervised Classification using time-series-aerial photographs of Bukhan, Cheonggae and Suri mountains because oak wilt disease seemed to be concentrated in the metropolitan regions. In order to analyze the spatial characteristics of the damaged areas, the geographical characteristics such as elevation and slope were statistically analyzed to confirm their strong correlation. Based on the results from the statistical analysis of Moran's I, we have retrieved the following: (i) the value of Moran's I in Bukhan mountain is estimated to be 0.25, 0.32, and 0.24 in 2009, 2010 and 2012, respectively. (ii) the value of Moran's I in Cheonggye mountain estimated to be 0.26, 0.32 and 0.22 in 2010, 2012 and 2014, respectively and (iii) the value of Moran's I in Suri mountain estimated to be 0.42 and 0.42 in 2012 and 2014. respectively. These numbers suggest that the damaged trees are distributed in clusters. In addition, we conducted hotspot analysis to identify how the damaged tree clusters shift over time and we were able to verify that hotspots move in time series. According to our research outcome from the analysis of the entire hotspot areas (z-score>1.65), there were 80 percent probability of oak wilt disease occurring in the broadleaf or mixed-stand forests with elevation of 200~400 m and slope of 20~40 degrees. This result indicates that oak wilt disease hotspots can occur or shift into areas with the above geographical features or forest conditions. Therefore, this research outcome can be used as a basic resource when predicting the oak wilt disease spread-patterns, and it can also prevent disease and insect pest related harms to assist the policy makers to better implement the necessary solutions.

• Journal of Korean Home Economics Education Association
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• v.17 no.2
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• pp.129-143
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• 2005

The purpose of this study was to verify the validity of Ohio State Teacher Efficacy Scale(OSTES: Tschannen-Moran, 2000) when used with Korean home economics teachers. To achieve this purposes, the surveys with 263 secondary school home economics teachers was conducted by the prime investigator. Statistical procedures included descriptive statistics, factor analysis, internal consistency. Cronbach's a was calculated to test the reliability of items and their internal consistency and Exploratory Factor Analysis(EFA) was conducted to test the structure of each factors with principal analysis and varimax rotation. Confirmatory Factor Analysis(CFA) was conducted to test the factor validity of this scale with AMOS program. The reliability test result of 20 items appeared Cronbach's a=.86. The factor analysis on teacher efficacy with 263 survey of secondary school home economics teachers produced 5 factors including efficacy in classroom management. efficacy in needs assistance, efficacy in instructional strategies, efficacy in environmental assistance and efficacy in teaming assistance. The validity of teacher efficacy scale was moderately verified by the confirmatory factor analyses(GFI=.87, AGFI=.84. CFI=.86. PNFI=.72, RMR=.05. RMSEA=.07). The results lend a support to the teacher efficacy scale as a valid instrument.

• Journal of Korean Society of Forest Science
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• v.97 no.2
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• pp.144-151
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• 2008

Using 8 isozyme polymorphic loci as gene markers, we studied the spatial distribution of genotypes in a naturally regenerated uneven-aged Eastern Siberian Fir (Abies nephrolepis Max.) stand (1ha, $100{\times}100m$) on Mt. Ohdae in northeastern South Korea. Gregorius' distograms and Moran's I correlograms revealed no evidence of significant genetic structure at three spatial classes of 5 m, 10 m, and 20 m. Extensive gene flow, due to the long distance dispersal of pollen and seeds in A. nephrolepis, may account for the lack of fine-scale spatial structure. Alternatives would be overlapping seed shadows caused by high densities of A. nephrolepis adult trees (160 trees/ha) and/or intraspecific competition resulting in extensive thinning within maternal half-sib groups.

• Journal of Chest Surgery
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• v.53 no.6
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• pp.381-386
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• 2020

Background: Behçet disease is a chronic inflammatory disorder with a varying etiology. Herein, we report the involvement of peripheral veins in Behçet disease and discuss the treatment thereof. Methods: Thirty-four patients with venous involvement in vasculo-Behçet disease were retrospectively analyzed over 15 years. We reviewed the clinical manifestations, treatment choices, and complications of these patients. Results: Deep vein thrombosis (DVT) was observed in 24 patients (70.59%) and varicose veins in 19 (52.94%). Immunosuppressive treatment was administered to all patients due to the pathological feature of vein wall inflammation. In patients with DVT, anticoagulation therapy was also used, but post-thrombotic syndrome was observed in all patients along with chronic luminal changes. Eleven patients with isolated varicose veins underwent surgery; although symptoms and lesions recurred in half of these patients, no cases of secondary DVT occurred. Conclusion: When DVT was diagnosed in patients with Behçet disease, there was no cure for the lesions. Ultrasonographic abnormalities were observed in all patients, and post-thrombotic syndrome remained to varying degrees. In cases of isolated varicose veins in patients with Behçet disease, DVT did not occur after surgical treatment. If the activity of Behçet disease is controlled, surgical correction of varicose veins is preferable.

• Asian-Australasian Journal of Animal Sciences
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• v.20 no.4
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• pp.461-465
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• 2007

Porcine Endogenous Retroviruses (PERVs) are a major concern in relation to xenotransplantation. Previous research indicated that PERVs are present at about 50 copies in the pig genome and their chromosomal insertion sites are different among pig breeds. We examined nine Korean native pigs and seven Asian Wild Boars for the presence of a PERV-A at SSC 1q2.4 and a PERV-B at SSC 7p1.1-2 previously reported in a Large White pig. The PERV-B at locus 7p1.1-2 displayed insertional variability in Korean native pigs and Asian Wild Boars. Using the primers for the PERV-A at 1q2.4 from Large White pig, we only can amplify an unclassified 798 bp sequence, which showed insertional variability only in Korean native pigs. This study indicates that there are differences within and between Asian and European pigs in PERV insertions and suggests that selection could generate PERV-free lines of pigs more suitable for xenotransplantation.

• Journal of the Korean Geographical Society
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• v.32 no.4
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• pp.527-540
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• 1997

이 글에서는 해외지역연구에 있어 세계와와 관련한 여건 변화, 지리하계의 동향, 그리고 21세기의 새로운 지역연구에 지리학의 역할이 어떠하여야 할 것인가를 살피고자 한다. 해외지역연구는 2차대전 이후 미국을 중심으로 발달하였다. 냉전기에 세계적 우위를 유지하고 국익을 보호하기 위하여 외국 현지어 구사 능력을 포함한 해외 정보 수요가 늘어 지역연구의 발달을 보게 된 것이다. 이러한 배경 때문에 지역연구는 개성기술적(ideographic)성격을 띠게 되었다. 요즘에는, 지역연구가 주로 초국적기업, 국제 경영대학원 등을 중심으로 이루어 지고 있다. 새 지역연구는 해외시장정보 수집 등 경제적 동기로 이루어지고 있어, 경제적으로 편향되는 취약점이 있다. 세계화는 요즘 하계의 화두(話頭)로, 세계 경제와 사회에 일고 있는 이 변화를 바로 이해하는 것은 향후 지역연구의 방향을 정립하는데 매우 중요하다. 세계화는 세계 어디서나 똑같이 일어나는 동질적인 현상이 아니라, 매우 다양하고 여러 의미가 담긴 현상이다. 마치 동전에 양면이 있듯이, 세계화는 수렴과 분화를 동시에 일으키고 있는 것이다. 따라서, 국경을 개방하고 장애를 없애 하나의 동질적인 세계시장환경을 지향하는 신자유경제 논리에 바탕한 지역연구는 설득력이 약하다. 지리학이 지역연구에 기여하기 위해서는 다음과 같은 노력이 계속되어야 한다. 첫째, 해외지역을 이해하려면 공간(space)과 장소(place)연구가 필수적이라는 점을 인식하고, 둘째, 인간과 환경의 상호작용 관점에서 지리적 차이를 파악하려는 노력이 필요하다. 셋째, 지리학은 이론정립 노력을 계속해야 하며, 넷째, 그 이론들은 해외지역의 현장답사와 정보수집을 통하여 검증되어야 한다. 지리학은 일찍부터 도시, 농촌 등 미시적 수준의 연구를 수행해왔기 때문에 경험적 연구에 강하다. 다섯째, 정부와 기업 등 조직에 대한 지리학적 연구가 이루어져야 할 것이다. 경제활동 분포에 대한 조직의 역할, 소유권에 대한 정부의 규제, 생산 조직의 환경 영향 등의 연구가 그 예이다. 여섯째, 지리학의 발달을 위하여 국가, 국제적 학술 기구를 활용하는 전략이 필요하다. 국제지리학연합(IGU)에서 개발한 지리교육과정, 미국National Research Council에서 세계지리에 밝지 못한 국민을 대상으로 펴낸 지리서 등이 그 사례이다. 지역연구는 사회과학 이론과 문화연구가 서로 접목되도록 새롭게 방향이 설정되어야 하며, 지리학의 인간-환경 연구 전통이 여기에 기여할 수 있을 것이다. 그러나 지리학의 역할이 효율적이기 위해서는 지리학 자체의 담론을 다시 확립해야 한다. 지리학계에서 지난 20여년간 추구해왔듯이 일반적 법칙을 지향(nomothetic)하는 접근법을 활용해야 하며, 여타 사회과학 및 환경과학과도 긴밀한 관련을 유지할 필요가 있는 것이다.

• Journal of Preventive Medicine and Public Health
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• v.52 no.1
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• pp.14-20
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• 2019

One of the primary goals of epidemiology is to quantify various aspects of a population's health, illness, and death status and the determinants (or risk factors) thereof by calculating health indicators that measure the magnitudes of various conditions. There has been some confusion regarding health indicators, with discrepancies in usage among organizations such as the World Health Organization the, Centers for Disease Control and Prevention (CDC), and the CDC of other countries, and the usage of the relevant terminology may vary across papers. Therefore, in this review, we would like to propose appropriate terminological definitions for health indicators based on the most commonly used meanings and/or the terms used by official agencies, in order to bring clarity to this area of confusion. We have used appropriate examples to make each health indicator easy for the reader to understand. We have included practical exercises for some health indicators to help readers understand the underlying concepts.

• Pediatric Infection and Vaccine
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• v.4 no.2
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• pp.232-239
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• 1997

Purpose: The incidence of hepatitis A virus(HAV) infection has markedly decreased in the last 20 years due to industrialization and improvements in the standard of living and hygiene in Korea. The reduction in seroprevalence rates indicates infection potential for young adult population, and a need for vaccinations in high-risk adults and children groups has been suggested. In this study we evaluated the seroprevalence rates and natural infection rates of hepatitis A in children and adolescent to obtain the basic data for vaccination of hepatitis A. Methods: A total of 334 children and adolescent subjects below 20 years old in Kyonggi-do province were examined for HAV antibody and seroprevalence rates in each age group was investigated. In 584 elementary school students residing in Kyonggi-do province, serum samples collected in 1993 and 1996 from the same subjects for investigation of natural seroconversion rates. Method of testing antibody was enzyme immunoassay. Results: 1) The seropositive rate of HAV in 334 subjects aged below 20 years old was 5.4%. According to age, the seropositive rates were 27.3% in infant group, 0.0% in 1~4 year-old group, 0.0% in 5~9 year-old group, 2.9% in 10~14 year-old group and 15.0% in 15~19 year-old group. 2) In the study of 584 elementary school children, only one subject showed seropositive in 1993, and in 1996 three different subjects showed seropositive results(0.5%); the natural seroconversion rate during 3 years was 0.5%. 3) The seroprevalence rates of below 20 year-old subjects reported in previous studies were 63.8% in 1979 and 47.3% in 1989 while the present study showed the rate at 5.4%. Conclusion: Since natural antibody formation is rarely occurring, there is a high risk for apparent hepatitis A infection in adults. Therefore vaccination in high risk groups is essential at present, and in order to reduce the chance for hepatitis A infection in adults, vaccination in children may be needed.