• Title/Summary/Keyword: Molecular characterization

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Enhancement of Dissolution from Pharmaceutical Preparation of Hydrophobic Drugs ( I ) -Characteristics of Sulpiride-Polyethylene Glycol Coprecipitates-

  • Ku, Young-Soon
    • Journal of Pharmaceutical Investigation
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    • v.12 no.4
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    • pp.145-152
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    • 1982
  • Data from IR spectroscopy and X-ray diffractometry were used for the characterization of sulpiride polyethylene glycol coprecipitates related with polymorphism of sulpiride. Sulpiride Form II transformed to Form I during coprecipitating with polyethylene glycol and the transformation rate is increased in proportion to molecular size of polyethylene glycol and the content of polyethylene glycol in coprecipitate.

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