• Biomolecules & Therapeutics
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• v.23 no.4
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• pp.379-385
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• 2015

The eye irritation potential of drug candidates or pharmaceutical ingredients should be evaluated if there is a possibility of ocular exposure. Traditionally, the ocular irritation has been evaluated by the rabbit Draize test. However, rabbit eyes are more sensitive to irritants than human eyes, therefore substantial level of false positives are unavoidable. To resolve this species difference, several three-dimensional human corneal epithelial (HCE) models have been developed as alternative eye irritation test methods. Recently, we introduced a new HCE model, MCTT HCE$^{TM}$ which is reconstructed with non-transformed human corneal cells from limbal tissues. Here, we examined if MCTT HCE$^{TM}$ can be employed to evaluate eye irritation potential of solid substances. Through optimization of washing method and exposure time, treatment time was established as 10 min and washing procedure was set up as 4 times of washing with 10 mL of PBS and shaking in 30 mL of PBS in a beaker. With the established eye irritation test protocol, 11 solid substances (5 non-irritants, 6 irritants) were evaluated which demonstrated an excellent predictive capacity (100% accuracy, 100% specificity and 100% sensitivity). We also compared the performance of our test method with rabbit Draize test results and in vitro cytotoxicity test with 2D human corneal epithelial cell lines.

• International Journal of Computer Science & Network Security
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• v.22 no.10
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• pp.340-346
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• 2022

Construction industry is considered as one of the oldest industries in the world since human came into being and the need of their own space is realized. All this led to make the world a space of many beautiful constructive ventures. As per the requirements of today's world, every industry is recognizing the need for use and adoption of modern as well as innovative technologies due to their benefits and timely production. Now construction industry has also started adopting the use of modern and innovative technologies during their projects but still the rate of adoption is so slow. From design to completion, construction projects take a lot to manage for which technology based solutions have continuously been proposed. These include Computer Aided Design (CAD), building information modeling (BIM) and cloud computing have been proved to be much successful until now. The construction projects are high budgeted, and direly require timely and successful completion with quality, resource and other constraints. So, the researchers observe the need of more clear and technology based communication between the construction projects and its constructors and other stakeholders is required before and during the construction to take timely precautions for expected issues. This study has analyzed the use of Augmented Reality (AR) technology adopting GammaAR, and ARki applications in construction industry. It has been found that both applications are light-weighted, upgradable, provide offline availability and collaborative environment as well as fulfil most of the requirements of the construction industry except the cost. These applications also support different screen size for better visualization and deep understanding. Both applications are analyzed, based on construction's application requirements, usability of AR and ratings of applications user collected from application's platform. The purpose of this research is to provide a detail insight of construction applications which are using AR to facilitate both the future developers and consumers.

• International Journal of Computer Science & Network Security
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• v.23 no.1
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• pp.64-70
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• 2023

Maritime transport is dominant in the overall volume of all international transportation. Existence and overcoming of problems, which cause pressure on shipping safety, remain actual and fully concern both maritime and inland transport. Increasing speed and cargo capacity of the ships along with the reduction of crew members lead to the automation of a growing number of work processes, which indicates the need to actively introduce appropriate measures in the security system of sea-going ships and commercial ports and to develop modern approaches to minimize negative events and incidents in the process of ship operation. Advantages in use of modern methods of monitoring the safety of ship operations, management of possible events and incidents, including investigation of accidents, first, aimed at prevention of negative occurrences and ways of prevention on this basis. Considering statistics on incidents increase, this work presents analysis of general ship accident rate, study of major accidental events growth annually, and investigation of causes of incidents, which most frequently occur in port waters and at open sea. A survey of current approaches to ensuring the safety of shipping by implementing effective tools, such as event and incident management, has been conducted.

• International Journal of Computer Science & Network Security
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• v.23 no.12
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• pp.137-144
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• 2023

The relevance of the research topic lies in the necessity to use social networks as innovative tools of marketing communications. A wide audience and the ability to segment the market for a specific consumer determine the construction of a corporate strategy, which will be based on using the social networking approach. The spread of the global coronavirus pandemic has led to the rapid development of remote communication channels between the company and the customer. The issue of using marketing tools in social networks acquires the most urgent importance in the modern world of the introduction and implementation of the company's marketing strategies. The purpose of the academic paper is to study the use of social networks as features of implementing the marketing campaign. Social networks are the result of the development of digital technologies and the processes of creating an information society involved in the digital space. The objectives of the research are to analyse the opportunity of using social networks as a tool for marketing communications and their implementation at the level of its widespread use by enterprises and establishments. It is significant to create an advertising campaign by defining the target audience and outlining the key aspects, on which the company is focused. The research methodology consists in determining the theoretical and methodological approaches to the essence of introducing social networks and their practical importance in the implementation of marketing activities of companies. The obtained results can significantly improve the quality of functioning of modern enterprises and organizations that plan to master a new market segment or gain competitive advantages in the existing one. The academic paper examines the essence of social networks as a tool of marketing communications. The key principles of the development of digital social platforms were revealed. The quality of implementing the advertising campaign in the social network was studied, and further prospects for the development of using social networks as a component of the marketing strategy were outlined. Therefore, the academic paper analyses the problems of using social networks as a marketing tool.

• The Research Journal of the Costume Culture
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• v.26 no.1
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• pp.73-81
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• 2018

Developments in the recent media era has made distortion possible in accordance with changes in the fashion industry as new clothing, technologies, and fusions have become available. Nevertheless, previous studies of specific types of clothing, and their classification for the purpose of research are lacking. Thus, this study examines the development of the Pomme de look and the form of modern variant that appears in fashion clothing and new technologies, and largely examines the clothing case to clean it up. The method employed is leading research that examines the transformation about the concept of the Pomme de look with regard to the fashion about the type of look in the 2000s and onwards. This is organized in accordance with the analytical and physical characteristics, and the esthetic aspects of the results are as follows. The conclusions reached as follows are based on this; first, the physical characteristic manner when based on previous looks, the two-dimensional deformation for making clothes, if there was a simple way, now has more dimensions. Clothes are made in a complex manner and variations emerge. Second, esthetic characteristics strive for beauty while also displaying the modified and more complex manners of clothing that are emerging. Third, the fusion clothing with machines effects to physical and psychological changes through the details about how the sensor is worn. The enemy, the appearance of distortion, and clothing are emerging. This is expected to grow further based on the rapid development of new technologies and the transformation of Pomme de look and design will appear in more varied ways to create a convergence.

• Animal Bioscience
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• v.34 no.3_spc
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• pp.354-362
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• 2021

Broiler chickens grow rapidly, and their nutrient requirements change daily. However, broilers are fed three to five diet phases, meaning nutrients are under or oversupplied throughout production. Increasing diet phases improves production efficiency as there is less time in the production cycle that nutrients are in under or over-supply. Nevertheless, the process of administering four or more diets is costly and often impractical. New technologies are now available to blend feed to match the daily nutrient requirements of broilers. Thus, the aim of this review is to evaluate previous studies measuring the impact of increasing feed phases on nutrient utilisation and growth performance, and review recent studies taking this concept to the extreme; precision nutrition - feeding a new diet for each day of the production cycle. This review will also discuss how modern precision feeding technologies have been utilised and the potential that new technologies may bring to the poultry industry. The development of a precision nutrition regime which targets daily requirements by blending dietary components on farm is anticipated to improve the efficiency of production, reduce production cost and therefore improve sustainability of the industry. There is also potential for precision feeding technology along with precision nutrition strategies to deliver a plethora of other management and economic benefits. These include increased fluidity to cope with sudden environmental or market changes, and the ability to alter diets on a farm by farm level in a large, integrated operation. Thus, the future possibilities and practical implications for such technologies to generate a paradigm shift in feed formulation within the poultry industry to meet the rising demand for animal protein is also discussed.

• International Journal of Computer Science & Network Security
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• v.22 no.8
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• pp.260-268
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• 2022

The article considers the training, competitiveness of specialists, professional mobility, professionalism and competence of specialists in the context of distance learning. The advantages of distance learning are shown. The characteristic features of distance learning in the preparation of students and in the implementation of these technologies in the educational process of higher educational institutions are determined. Competitiveness, professional mobility, professionalism and competence of a specialist are qualities that determine a person's life and work success. Professional mobility is interpreted as a systemic quality of a specialist's personality, which includes a whole range of knowledge, skills, abilities, personal qualities, value orientations, and so on. The vision of mobility of specialists by foreign scientists is presented. It is noted that the classification of professional mobility presented in the article makes it possible to organize various movements from a single position, to present them as separate manifestations of the general process of professional and pedagogical mobility, to determine which type of mobility ensures the performance of certain social functions. It was found that mobility can be differentiated into differentiated and intergeneration. According to the subject, individual and group mobility are distinguished; according to the direction - internal and external. The classification of employees according to their attitude to mobility is shown, which can be divided into the following groups: actually mobile; potentially mobile; actually stable; potentially stable.

• International Journal of Computer Science & Network Security
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• v.22 no.10
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• pp.183-190
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• 2022

The article analyzes the features of the formation of a person's value attitude to the worldview by means of information technologies. The present considers it necessary to form a person's value attitude to the perception of the world by means of information technologies. The explosive development of information and telecommunications technologies has become a determining factor in the development of modern society, which is called the information or Global Information Society. It is not yet fully formed, and we are all participants in the development of the Global Information Society. The article considers the basics of a harmonious worldview of a person, which is the basis for the formation of outlook ideas, views, knowledge, beliefs about the surrounding world, which determine the place and role and motivate actions in relation to the surrounding reality through the prism of value orientations. Worldview is considered as an integrity of relatively stable schemes, behaviors, feelings, thinking, vision of the surrounding world, inherent in an individual child, ethno-cultural and socio-cultural groups. The concept of "worldview" as a component of the multi-level structure of the individual's outlook is defined. The features that characterize a person's perception of the world are revealed. The main educational value of information technologies in the formation of a person's value attitude to the perception of the world is highlighted, which consists in the fact that they allow you to create an immeasurable brighter multi-sensory interactive learning environment with almost unlimited potential opportunities that fall at the disposal of both the teacher and the student. The trend of forming a person's value attitude to the perception of the world is clearly developing in the direction of mixed learning as a process that creates a comfortable information educational environment, communication systems that provide all the necessary educational information. The approach to student development by means of the educational environment and the formation, while in the person of a value attitude to the perception of the world by means of Information Technologies, has many pedagogical advantages, which is considered in the article.

• Journal of Society of Preventive Korean Medicine
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• v.20 no.1
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• pp.99-110
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• 2016

In Korea and China, traditional medicine's holistic approaches, based on the views of whole-body and whole-person, have been applied to make the solution of health problem. However, these holistic approaches of traditional korea or chinese medicine have been limited in interpreting their theories in a view of modern scientific aspects of medicine. This limitation seems to be mainly due to the reductionism approaches of modern scientific medicine. Traditionally, science has taken a reductionism approach; dissecting biological systems into their constituent parts and studying them in isolation. However, systems biology based on omics technologies is providing a new thought and method for traditional medicine's research and interpretation. Systems biology uses integrity study as the characteristic and bioinformatic technology as the key method for connecting reductionism and holism. Therefore, it has much in common with the theory of traditional medicine. It was reviewed that how systems biology is applied to traditional medicine in Korea and China. Also it was suggested that more future researches on interpretation between traditional medicine and systems biology must be focused on personalized medicine since systems biology will have a major impact on future personalized therapeutic approaches.

• Korean Institute of Interior Design Journal
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• v.16 no.1 s.60
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• pp.48-55
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• 2007

Proceedings in a new field of sciences and technologies like genetic engineering challenge to conventional concepts. It demonstrates a certain disappearance in conventional concepts that dominants our perceptions, such as organic, mechanical, and dichotomic concept of informative materials, and that is to be extended as a potential possibility. Then, what is a new space where our bodies that feel and cherish in their mind should live in these days as well as it makes senses by itself and should affect the principle that makes worlds? In addition, this study proposes a frame in the analysis in order to understand a section of modern designs with the question of 'what is the change in the relationship between relative structures in spaces and objects from a design point of view according to new structural concepts of body?' The major point of this analysis can be realized based on the assumption of the extension of the characteristics in the change of structural relationship in the aspect of post structuralism that includes non-structuralized relationship represented in modern philosophy, arts, and architectural works. Then, it can be accomplished as positive ideas in the foundation of space designs in future including the understand of 'new structural relationship' that can't be expressed as rationality and causal sequence by considering how the experiment conducted using several topics on body can be projected onto spaces through the process applied in the experiment.