• 대한예방의학회:학술대회논문집
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• 1994.02b
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• pp.336-341
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• 1994

Multicenter controlled clinical trials require It synthesis of the scientific method and the precepts of modern management. The management tasks associated with these studies are akin to those found in other kinds of complex corporate endeavors. It is recommended that clinical investigators become more knowledgeable about management concepts and methods and management specialists be given a major role in the planning and conduct of large-scale clinical trials.

• Korean Journal of Pharmacognosy
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• v.3 no.4
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• pp.187-197
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• 1972

In spite of the fact that the system of oriental medicine still remains in the realm of 'unproven-method of treatment', no one can deny that the oriental medicine is a rich source of idea and motivation for the discovery of new drug from natural sources. However, non-scientific, mystic hypothetical system of oriental medicine refuses to be revealed scientifically. For the purpose of drawing useful parameters for inductive reasoning of the system, a new approach which comprises statistical analyses of prescription was attempted in this study. One hundred and thirty two ginseng-compounds prescription in 'Bang-Yak-Hap-Pyon', one of the most popular formularies of oriental medicine in Korea, were analysed by multivariate analysis technique. The results revealed ginseng from many points of view, e.g., therapeutic indications, dose, and compatibility, etc. Among these, the most striking coincidence with scientific achievements of modern pharmacology, is the fact that the oriental medicine has characterized ginseng already from remote ancient times as neither a specific curative nor an aphrodisiac, but a non-specific adaptogenic drug for general infirmity.

• Journal of Korean Medical classics
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• v.26 no.4
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• pp.89-94
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• 2013

Objective : To collect cosmetology text in Shang Han Za Bing Lun(伤寒杂病论), to analyze theory and prescription about cosmetology before HAN(漢) dynasty, so to allow records for modern cosmetology of Traditional Chinese Medicine. Method : Through the systematize for all terms about cosmetology, to reveal the regularity about cosmetology before HAN(漢) dynasty. Result : There were damage-appearance disease in HAN(漢) dynasty, there are lots of ideas about cosmetology in Shang Han Za Bing Lun(伤寒杂病论). Conclusion : Shang Han Za Bing Lun(伤寒杂病论) is a monograph about pattern identification and treatment, and is an important ancient book for research of cosmetology of Traditional Chinese Medicine. In the further, we will research in knowledge discovery about cosmetology of Traditional Chinese Medicine. to strengthen the guidance of the theory of Zhang Zhongjing(张仲景) for clinical practice of cosmetology of Traditional Chinese Medicine.

• Korean Journal of Oriental Medicine
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• v.10 no.1
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• pp.81-95
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• 2004

The discussion of intellectual property protection with TK, GR in WIPO begin Herbal medicines get a important basis in a development of modern new medicine. For the protection of intellectual property, we set up this study. For the protection of intellectual property with herbal medicines, We analyze as follows. First, we analyze the specific theory and character of traditional herbal medicines. Second, we analyze the existing system on protecting them in Korea. The intellectual property protection with herbal medicines must maintain the specific character of that. We must select the basic traditional herbal medicines. The next, we must protect from intellectual property on add and subtract, combine, create of the traditional herbal medicines. In order that we must construct database on the Herbal medicines.

• Journal of Physiology & Pathology in Korean Medicine
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• v.17 no.5
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• pp.1147-1150
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• 2003

Modern Objectification of Pulse Diagnosis, One of the Four Diagnosis Method of Oriental Medicine, is necessarily project to improving Oriental medical clinic status and quality by standardization of diagnosis database. At that, accurate measurement equipment or devices(sensor, system and instruments, etc,) to exactly detect MacSang(脈診 : the parameter and subject of pulse diagnosis) have not developed yet. Existing Pulse diagnosis devices are not satisfy clinical needs and medical equipments quality. We study for pulse diagnosis system, that CD is satisfying oriental medical clinic needs, is ensuring accuracy and reappearance to support in clinical diagnosis and treatment, is guaranteeing the quality of medical equipments. theoretical base and convenience.

• Korean Journal of Acupuncture
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• v.25 no.4
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• pp.31-47
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• 2008

Objectives : The objective of this study is to apply the contents of "WaHyul(訛穴 : The errors of acupoint locations"of "ChimGuKyungHumBang" to modern acupoint locations. Methods : The text of "WaHyul" was closely examined and analyzed. "WHO standard acupuncture point locations in the western pacific region" was reviewed based on its contents. Results : According to the analysis, the correct 少商(LU11) was mentioned as a spot appropriately distanced from the corner of the nail root under the skin. This is the most accurate and reasonable synthesis of other related texts. Furthermore, the necessity of defining the locations of all the well points was also emphasized and their locations were mentioned that could be located by the same method. There is no further discussion of other acupoints apart from descriptions of their locations from other texts. Some parts that were pointed out as common errors included not only commonly made mistakes, but errors made in acupuncture texts as were true for 神門(HT7) and 肩井(GB21). The standards of 少商(LU11), 合谷(LI4) and 足三里(ST36) presented in the WHO Standardization are not only similar to what 「WaHyul」 indicated as errors in acupoint locations, but also deviate other acupuncture texts; appropriate corrections must be made. The standard of 肩井(GB21) presents a new acupoint locating method never mentioned before in received classic acupuncture texts and so a rediscussion is in need. Other standards, such as the 絶骨(GB39), had some points of controversy, yet somewhat incomplete while HT7 did not go beyond the bounds of "WaHyul". Conclusions : "WaHyul" can be used to revise WHO standards, and has practical value in modern acupoint locating.

• Journal of Korean Neurosurgical Society
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• v.60 no.3
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• pp.335-347
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• 2017

Intravenous recombinant tissue plasminogen activator had been the only approved treatment for acute ischemic stroke since its approval in 1995. However, the restrictive time window, numerous contraindications, and its low recanalization rate were all limitations of this modality. Under those circumstances, endovascular stroke therapy went through a great evolution during the past two decades of intravenous thrombolysis. The results of the 2013 randomized trials for endovascular stroke therapy were neutral, although they were limited by insufficient imaging screening at enrollment, early-generation devices with less efficacy, and treatment delays. Huge progress was made in 2015, as there were five randomized clinical trials which all demonstrated the safety and efficacy of endovascular stroke treatment. Despite differences in detail patient enrollment criteria, all 5 trials employed key factors for good functional recovery; (1) screening with non-invasive imaging to identify the proximal occlusion and exclude a large infarct core, (2) using highly effective modern thrombectomy devices mainly with stent retriever, and (3) establishment of a fast workflow to achieve effective reperfusion. The results of those trials indicate that modern thrombectomy devices can allow for faster and more effective reperfusion, which can lead to improved clinical outcomes compared to intravenous thrombolysis alone. These advances in mechanical thrombectomy are promising in the global fight against ischemic stroke-related disability and mortality. Two current mainstreams among such mechanical thrombectomy techniques, "stent retriever thrombectomy" and "direct clot aspiration", are the topic of this review. Stent retriever thrombectomy using Solitaire and Trevo retriever will be firstly discussed. And, the commonalities and the differences between two major clot aspiration thrombectomy techniques; a direct aspiration first pass technique (ADAPT) and forced arterial suction thrombectomy (FAST), will be additionally explained. Finally, details regarding the combination of direct clot aspiration and stent retriever thrombectomy, the switching strategy and the Solumbra technique, will be described.

• Journal of Korean Medical classics
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• v.29 no.2
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• pp.1-12
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• 2016

Objectives : This study selected the food ingredients mainly appearing in the stomach-disease-related articles from Eumsunjungyo Singnyojaebyeong and Singnyochanyo, and investigated their effects to turn these data into references for modern people, use the food therapy of ancestors for modern life, and prevent and cure stomach diseases of modern people due to unhealthy lifestyle. Methods : This study selected the stomach-related food therapies from Eumsunjungyo and Singnyochanyo, and organized the therapies by chief virtue, effect, ingredient, and recipe. Also, this study analyzed and investigated characteristics, tastes, and target organs of the food ingredients in the recipes. Results : There are 8 stomach-related recipes among 61 recipes in Eumsunjungyo Singnyojaebyeong, and there are total 34 types of stomach-related recipes in Singnyochanyo including 27 types of BiwiBuBanui Five and 7 types of GutoBuHaeyeokByeonggyeonBiwi fifteen. Both Eumsunjungyo Singnyojaebyeong and Singnyochanyo contains food therapies for diseases due to week stomach. Most recipes in Singnyochanyo uses only food ingredients, whereas most recipes in Eumsunjungyo Singnyojaebyeong uses ingredients which can be used as medicine. Conclusions : The food therapies in Eumsunjungyo Singnyojaebyeong and Singnyochanyo proves that people in all regions have used food to cure diseases from old times. On the other words, people have clinically used the characteristics, tastes, and cooking forms of food ingredients for a long time. Thus, this study can be a reference for creating another food therapy.

• Korean Institute of Interior Design Journal
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• v.26 no.6
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• pp.42-52
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• 2017

In this modern world of drastic change, folding architecture was an alternative that offered a novel architectural insight. Today, the folding technique is being used above and beyond architecture, spreading to fashion, lighting, medicine, etc. Especially in the interior space design field, the folding technique is in the limelight as an alternative to create an original space for modern society. However, research and experiments into folding mainly remains at philosophical interpretation or architectural examples, and even these were mostly before the 2000s. Therefore, the present study determined it necessary to look deeply into the post-2000s folding technique focusing on interior space. In this paper, 33 cases of indoor space where folding technique appears are derived, and classified them again by use. The folding technique which was the first step of Sophia Vyzoviti's experiment on her book, "Folding Architecture" was extracted and used as the framework. We summarizes the range of application of folding techniques (interior space in general, floor, wall, ceiling, etc.) and major folding techniques by combining photographs, drawings, and descriptions of the works of the architects. This paper summarizes the characteristics of the space described comprehensively, and draws out the spatial characteristics of the modern interior space where the folding technique appears.

• Journal of Sasang Constitutional Medicine
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• v.30 no.1
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• pp.66-73
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• 2018

Objectives The purpose of this study was to develop mobile a application that evaluate the Mibyeong(deterioration of the health) in daily life and provide optimal Yangseng(養生) interventions according to the Korean medicine types. Methods The evaluation of Mibyeong utilized questionnaire or objective informations including Facial photographs and hemodynamic information. The Korean medicine type classification was reconstructed based on the concept of Sasang constitution and cold-heat pattern identification. Yangseng interventions were recommended based on Mibyeong symptoms, Korean medicine types, and demographic information. And we have developed tracking and ranking functions for user motivations. We used a Korean medicine database that focused on healthy people as a reference data, and used Yangseng interventions database that reinterpreted classical Yangseng in a modern way. Results and Conclusions We have developed a mobile application that evaluates the user's Mibyeong state and provides optimal Yangseng interventions based on Korean medicine types. This study are expected to improve the quality of health and contribute to the prevention of diseases.