• 대한한의학원전학회지
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• 제27권4호
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• pp.133-151
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• 2014

Objectives : In this study, the changes of concept of Bianzheng(辨證)[syndrome differentiation] in the traditional medical history are investigated for the purpose of understanding conditions of Korean Medicine in modern times. Methods : The concepts of Zheng(證)[syndrome] and Bianzheng[syndrome differentiation] in Sanghanron(傷寒論) and many important medical literatures were selected and analyzed to overview the historical changes of those. Results : To the modern ages, the concept of Zheng had included the two kinds of concepts, that is, symptom/sing and syndrome with slight changes of meaning. As a abstract meaning of syndrome, Zheng(證) has been systematized and complicated with the times, that means changes of syndrome differentiation. The concept of Zheng has been recognized as the symbol that expresses the characteristics of Traditional Medicine since the modern age that concepts of sign and symptom have flowed from Western Medicine into Traditional Medicine. Conclusions : One of the main key of studies about Bianzheng(辨證) in future would have been harmonizing the balance between the two trends of modern Traditional Medicine, ideation and objectification.

• 한국의사학회지
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• 제24권1호
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• pp.97-110
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• 2011

Rhinitis, inflammation of the nasal cavity caused by the disease in our country that a recent trend is the rapidly increasing number of patients. It causes multiple complications and interfere with daily life and social life in case of being viewed as a mild cold. The rhinitis treatment for symptomatic therapy in modern medicine is staying because the situation is exposing the limitations. so traditional medicine is trying to find a solution but that is not easy. In modern medicine, rhinitis is defined as a set of histological lesions and clinical symptoms, but traditional medicine has developed in dealing with each symptoms in disease. The treatment that doesn't distinguish any treatment in growing numbers of patients does not seem to validate, because doctors treat without considering the difference of recognition. Looking at the symptoms for each, I found that each symptoms and causes are varied according to doctors and era. In spite of considering all of that in treatment, it was ignored or underestimated in modern medicine. Furthermore, in traditional medicine, they just conjugated certain period theory and only had limited treatment by a lack of integrated awareness about definition and mechanism. In addition, in case of mentioning about the causes of prescription in each medical books, there were not enough explain about pathological states. Therefore, these causes should be made to further the research about the validity, pathogenesis and treatment. We can see that theory could be established and modified by the accumulation of clinical experience, observations through classification by each of the causes, prescription and treatment. In traditional medicine simply does not pay attention only to nasal inflammation, such as the impact of Meridian and organs considered to have focused on the fundamental treatment. This increased immune resistance to the modern rhinitis patients may offer new therapeutic approaches. I hope this paper would be helpful to find the treatment with uncovered theory in modern medicine.

• 사상체질의학회지
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• 제30권1호
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• pp.7-13
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• 2018

Objectives On the point of modern preventive medicine, Sasang Constitutional Meidicine(SCM) has the thoughts of preventive medicine. Modern preventive medicine has the three dimensional prevention; primary, secondary and tertiary prevention. The preventive thoughts of SCM concerning three dimensional prevention have been investigated in this article. Method Materials and references were collected about the prevention of SCM. Lee Jema's books such as Donguisusebowon, Gyeokchigo and Donguisusebowon Chobonguen were included. Result and Conclusions As the primary prevention of SCM, Regimen according to ages, explanation according to health index as Myeongmaeksilsu(命脈實數), moderation of four ruinous causes such as intoxication, seduction, opulence and authority, adequate social life and control of 4 kinds of emotions(sorrow, anger, joy and pleasure) are included. As the secondary prevention of SCM, explanation according to disease index, fragile Organs and frequently acquired diseases according to constitutions are included. As the tertiary prevention of SCM, rehabilitation for the stroke patients according to constitutions is included. In conclusion, SCM has all of 3 dimensional prevention methods although that might be applied with modern considerate modification.

• The Korean Journal of Physiology and Pharmacology
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• 제26권3호
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• pp.145-155
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• 2022

Multidrug resistance of tumors has been a severe obstacle to the success of cancer chemotherapy. The study wants to investigate the reversal effects of imperatorin (IMP) on doxorubicin (DOX) resistance in K562/DOX leukemia cells, A2780/Taxol cells and in NOD/SCID mice, to explore the possible molecular mechanisms. K562/DOX and A2780/Taxol cells were treated with various concentrations of DOX and Taol with or without different concentrations of IMP, respectively. K562/DOX xenograft model was used to assess anti-tumor effect of IMP combined with DOX. MTT assay, Rhodamine 123 efflux assay, RT-PCR, and Western blot analysis were determined in vivo and in vitro. Results showed that IMP significantly enhanced the cytotoxicity of DOX and Taxol toward corresponding resistance cells. In vivo results illustrated both the tumor volume and tumor weight were significantly decreased after 2-week treatment with IMP combined with DOX compared to the DOX alone group. Western blotting and RT-PCR analyses indicated that IMP downregulated the expression of P-gp in K562/DOX xenograft tumors in NOD/SCID mice. We also evaluated glycolysis and glutamine metabolism in K562/DOX cells by measuring glucose consumption and lactate production. The results revealed that IMP could significantly reduce the glucose consumption and lactate production of K562/DOX cells. Furthermore, IMP could also remarkably repress the glutamine consumption, α-KG and ATP production of K562/DOX cells. Thus, IMP may sensitize K562/DOX cells to DOX and enhance the antitumor effect of DOX in K562/DOX xenograft tumors in NOD/SCID mice. IMP may be an adjuvant therapy to mitigate the multidrug resistance in leukemia chemotherapy.

• 대한예방한의학회지
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• 제27권2호
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• pp.73-84
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• 2023

Objectives : We tried to propose the direction of Korean medicine education through the consideration of 'professionalism as a competency beyond knowledge-skill' that modern medicine should take and therefore the perspectives of the competency-based curriculum in Korean medicine education. Methods : Competency-based curriculum, professionalism education phase and competency at medical school, student demand survey, Korean medicine education Accreditation Standards, and related research articles were used. Results : Proposed development measures to cultivate students' professionalism in Korean medicine education are as follows. self-care and emotional stability programs, communications between patient and doctor and among the colleagues, career exploration programs based on global medical trends and government policy, standardized professional training programs, and the evaluation of teaching experiences and achievements. Conclusions : The main purpose of the reorganization of the competency-based curriculum should be for improving Korean medicine education. The contents of phase performance, process performance, and course performance should be carefully organized so that the core contents and spirit of traditional Korean medicine can be achieved. In modern medicine, education of professionalism has been used to cover the problems that arise from taking achievement goals only from a biomedical perspectives. Accordingly the education of professionalism is also important in Korean medicine education as the modern Korean medicine follows the aspect of modern medicine,

• 동의생리병리학회지
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• 제27권5호
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• pp.487-496
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• 2013

This article is a study on to which categories of modern diseases qi deficiency pattern types are assigned by reference to modern clinical papers to analyze and understand modern diseases with the perspective of Korean Medicine. Clinical papers were searched in China Academic Journals(CAJ) of China National Knowledge Infrastructure(CNKI) from 1994 to 2013. Conclusions are as follows. First, qi deficiency pattern types are roughly classified as qi deficiency pattern, qi-yin dual deficiency pattern and qi deficiency pattern related with viscera and bowels. Second, there are many patterns combined with static blood, qi stagnation, phlegm, dampness, heat, toxin, water or fluid deficiency and the level of pattern designation is more specific than pattern types in Korean Standard Classification of Diseases(KCD), which makes the pattern types more useful to clinical application. Third, static blood due to qi deficiency is the most frequent combined pattern and diseases related with blood circulation such as angina, atherosclerosis, hyperlipidemia and chronic obstructive pulmonary disease(COPD) were reported on that pattern. The detailed relation between modern diseases and pattern types can be an another topic.

• 한방재활의학과학회지
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• 제26권1호
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• pp.63-77
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• 2016

Objectives The objective of this study is to interpretate Yangsaeng-Doinbub presented in [Jebyungwonhuron Huhrobyungjehu] in a modern kinesiologic approach. Methods Based on the interpretation of [Jebyungwonhuron Huhrobyungjehu] and implementation of its kinesiology, this study presents similar kinesiologies and their purposed, with the reference to various documents on modern kinesiology. Results 1) Exercises in Yangsaeng-Doinbub presented in [Jebyungwonhuron Huhrobyungjehu], which are similar to resistance exercise, can be used for isometric exercise of knee joint extensor and cervical extensor. 2) Exercises in Yangsaeng-Doinbub presented in [Jebyungwonhuron Huhrobyungjehu], which are similar to stretching exercise, has its purpose to stretch semitendinosus m., semimembranous m., gastrocnemius m., quadriceps femoris m., upper trapezius m., levator scapulae m., serratus m., and splenius capitis m. 3) Exercises in Yangsaeng-Doinbub presented in [Jebyungwonhuron Huhrobyungjehu], which are similar to active exercise, can be used for strengthen quadriceps femoris m.. 4) Yangsaeng-Doinibub also describes breathing methods, which help normalization of breathing exercised and increase the efficiency of spine and joint exercises. Conclusions The modern interpretation on kinesiology of Yangsaeng-Doinbub presented in [Jebyungwonhuron Huhrobyungjehu] leads to a conclusion that Yangsaeng-Doinbub consists of various exercises for knee joint, neck and upper extremity.

• Journal of Acupuncture Research
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• 제35권3호
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• pp.101-103
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• 2018

Cupping therapy (CT) is used in Asia, Europe, and the Middle East and is prevalent in Muslim communities where it is recommended by the Prophet of Islam. The majority of modern, medical practitioners interested in CT, view it as a medical technique and distance themselves from the mechanisms proposed by traditional medicine. However, modern medicine does not offer a valid explanation for the mechanisms involved in CT. There is growing evidence of CT's effectiveness, specifically in chronic pain management when compared to an inactive control, but not against sham treatment. CT accompanied by religion and prayer, as it is in Muslim communities, cannot be considered to be equivalent to any procedures in modern medicine. "Whole System Research" may be the most appropriate trial design to test the ancient practice of CT efficacy whilst pending development of a novel placebo for assessing the connectivity of body and mind interventions.

• 한국콘텐츠학회논문지
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• 제22권6호
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• pp.428-438
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• 2022

본 연구는 약사여래 신앙의 현대적 의미와 신앙적 가치를 고찰하는 데 목적을 두었다. 이에 따라 약사여래에 관한 대표적 문헌인 『약사경』을 비롯해 여러 문헌 자료에 기초해 약사여래 신앙에 대한 이론적 배경에 대해 고찰을 하였고, 뒤이어 약사여래 신앙의 2가지 핵심 지향점인 질병의 치유와 횡사의 구제를 종류 및 유형, 방법으로 구분해 분석 틀을 설정한 뒤 내용 분석을 하였다. 본 연구의 결과로서 약사여래 신앙이 갖는 현대적 의미와 신앙적 가치를 다음과 같이 제시하였다. 먼저 약사여래 신앙이 갖는 현대적 의미이다. 약사여래 신앙은 첫째, 질병이 치료가 아닌 치유의 대상이라는 관점 전환을 촉진한다. 둘째, 약사여래 신앙은 질병을 의학적 질환뿐만 아니라 장애로까지 확대하여 치유의 대상으로 삼는다. 셋째, 약사여래 신앙은 마음의 긍정성을 강화하는 수행을 통해 치유를 도모한다. 다음 약사여래 신앙이 갖는 신앙적 가치이다. 약사여래 신앙은 첫째, 신앙적 수용성이 강력하다. 둘째, 약사여래 신앙은 종교와 종파를 뛰어넘어 현대인에게 수용되고 있다는 특징을 갖고 있다. 이러한 연구 결과를 토대로 본 연구는 질병과 횡사 등으로 일상생활 속에서 고통에 시달리고 있는 현대인들의 삶의 질 증진을 위한 제언을 하였다.

• Advances in Traditional Medicine
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• 제8권1호
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• pp.17-23
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• 2008

While full recognition of the practical value of Traditional Chinese Medicine is being endorsed, the current stand on the research methodology of this field should be worked out. Since modern medicine has already developed a logical system of research methodology basing on the principles of deduction, any research on any system of medicine need to take reference to what is most popularly used and commonly recommended. The best way to approach research on Chinese Medicine, therefore, would be one that would take full reference to the methodology being used in modern medicine, while at the same time respecting the traditional approach. This would enable traditional medicine to be elevated to the level of general modern recognition. Nevertheless, innate problems in traditional medicine are making its research difficult. The problems lie in difficulties to achieve uniform herb supply, principles of randomization and placebo arrangements, uncertain chemical structures and toxicology etc. A practical approach centered on carefully planned evidence-based clinical trials, with parallel studies on biological activities and herb authentication is being recommended.