• Animal Bioscience
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• v.35 no.5
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• pp.648-658
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• 2022

Objective: The identification of nonlinear mixed models that describe the growth trajectory of New Zealand rabbits was performed based on weight records and carcass measures obtained using ultrasonography. Methods: Phenotypic records of body weight (BW) and loin eye area (LEA) were collected from 66 animals raised in a didactic-productive module of cuniculture located in the southern Piaui state, Brazil. The following nonlinear models were tested considering fixed parameters: Brody, Gompertz, Logistic, Richards, Meloun 1, modified Michaelis-Menten, Santana, and von Bertalanffy. The coefficient of determination (R²), mean squared error, percentage of convergence of each model (%C), mean absolute deviation of residuals, Akaike information criterion (AIC), and Bayesian information criterion (BIC) were used to determine the best model. The model that best described the growth trajectory for each trait was also used under the context of mixed models, considering two parameters that admit biological interpretation (A and k) with random effects. Results: The von Bertalanffy model was the best fitting model for BW according to the highest value of R² (0.98) and lowest values of AIC (6,675.30) and BIC (6,691.90). For LEA, the Logistic model was the most appropriate due to the results of R² (0.52), AIC (783.90), and BIC (798.40) obtained using this model. The absolute growth rates estimated using the von Bertalanffy and Logistic models for BW and LEA were 21.51g/d and 3.16 cm², respectively. The relative growth rates at the inflection point were 0.028 for BW (von Bertalanffy) and 0.014 for LEA (Logistic). Conclusion: The von Bertalanffy and Logistic models with random effect at the asymptotic weight are recommended for analysis of ponderal and carcass growth trajectories in New Zealand rabbits. The inclusion of random effects in the asymptotic weight and maturity rate improves the quality of fit in comparison to fixed models.

• Asian-Australasian Journal of Animal Sciences
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• v.13 no.5
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• pp.575-579
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• 2000

First lactation records of 683 Murrah buffaloes maintained at NDRI, Karnal which were progeny of 84 sires used for comparing the heritability estimates of age at first calving, first lactation milk yield and first service period under single and multiple trait models using restricted maximum likelihood (REML) method of estimation under an individual animal model. The results indicated that the heritability estimates may vary under single and multiple trait models depending upon the magnitude of genetic and environmental correlation among the traits being considered. Therefore, a single or multiple trait model is recommended for estimation of variance components depending upon the goal of breeding programme. However, there may not be any advantage of considering a trait with zero or near zero heritability and having no or very low genetic correlation with other traits in the model. Lower heritability estimates of part lactation yield (120-day milk yield) implied that there may not be any advantage of considering this trait in place of actual 305-day milk yield, whereas, comparable heritability estimates of predicted 305-day milk yield suggested that it could be used for sire evaluation to reduce the cost of milk recording under field conditions.

• Journal of Animal Science and Technology
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• v.63 no.3
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• pp.603-613
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• 2021

This research improved the growth potential of Bifidobacterium animalis subsp lactis strain JNU306, a commercial medium that is appropriate for large-scale production, in yeast extract, soy peptone, glucose, L-cysteine, and ferrous sulfate. Response surface methodology (RSM) was used to optimize the components of this medium, using a central composite design and subsequent analyses. A second-order polynomial regression model, which was fitted to the data at first, significantly lacked fitness. Thus, through further analyses, the model with linear and quadratic terms plus two-way, three-way, and four-way interactions was selected as the final model. Through this model, the optimized medium composition was found as 2.8791% yeast extract, 2.8030% peptone soy, 0.6196% glucose, 0.2823% L-cysteine, and 0.0055% ferrous sulfate, w/v. This optimized medium ensured that the maximum biomass was no lower than the biomass from the commonly used blood-liver (BL) medium. The application of RSM improved the biomass production of this strain in a more cost-effective way by creating an optimum medium. This result shows that B. animalis subsp lactis JNU306 may be used as a commercial starter culture in manufacturing probiotics, including dairy products.

• The Journal of Korea Institute of Information, Electronics, and Communication Technology
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• v.10 no.1
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• pp.85-94
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• 2017

In this paper, I proposed a sound model generation and a most frequent model search algorithm for recognizing animal vocalization. The sound model generation algorithm generates a optimal set of models through repeating processes such as the training process, the Viterbi Search process, and the most frequent model search process while adjusting HMM(Hidden Markov Model) structure to improve global recognition rate. The most frequent model search algorithm searches the list of models produced by Viterbi Search Algorithm for the most frequent model and makes it be the final decision of recognition process. It is implemented using MFCC(Mel Frequency Cepstral Coefficient) for the sound feature, HMM for the model, and C# programming language. To evaluate the algorithm, a set of animal sounds for 27 species were prepared and the experiment showed that the sound model generation algorithm generates 27 HMM models with 97.29 percent of recognition rate.

• Animal Bioscience
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• v.36 no.6
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• pp.879-890
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• 2023

Objective: This study was conducted to evaluate the use of Megasphaera elsdenii (M. elsdenii) as a probiotic on rumen fermentation, production performance, carcass traits and health of ruminants by integrating data from various related studies using meta-analysis. Methods: A total of 32 studies (consisted of 136 data points) were obtained and integrated into a database. The parameters integrated were fermentation products, rumen microbes, production performance, carcass quality, animal health, blood and urine metabolites. Statistical analysis of the compiled database used a mixed model methodology. Different studies were considered random effects, while M. elsdenii supplementation doses were considered fixed effects. p-values and the Akaike information criterion were employed as model statistics. The model was deemed significant at p<0.05 or had a tendency to be significant when p-value between 0.05<p<0.10. Results: Supplementation with M. elsdenii increased (p<0.05) some proportion of fermented rumen products such as propionate, butyrate, isobutyrate, and valerate, and significantly reduced (p<0.05) lactic acid concentration, acetate proportion, total bacterial population and methane emission. Furthermore, the probiotic supplementation enhanced (p<0.05) livestock production performance, especially in the average daily gain and body condition score. Regarding the carcass quality, hot carcass weight and carcass gain were elevated (p< 0.05) due to the M. elsdenii supplementation. Animal health also showed improvement as indicated by the lower (p<0.05) diarrhoea and bloat incidences as well as the liver abscess. However, M. elsdenii supplementation had negligible effects on blood and urine metabolites of ruminants. Conclusion: Supplementation of M. elsdenii is capable of decreasing ruminal lactic acid concentration, enhancing rumen health, elevating some favourable rumen fermentation products, and in turn, increasing production performance of ruminants.

• Development and Reproduction
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• v.19 no.2
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• pp.79-84
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• 2015

The Korean native pig (KNP) have been considered as animal models for animal biotechnology research because of their relatively small body size and their presumably highly inbred status due to the closed breeding program. However, little is reported about the use of KNP for animal biotechnology researches. This study was performed to establish the somatic cell nuclear transfer (SCNT) protocol for the production of swine leukocyte antigens (SLA) homotype-defined SCNT KNP. The ear fibroblast cells originated from KNP were cultured and used as donor cell. After thawing, the donor cells were cultured for 1 hour with 15 ${\mu}M$ roscovitine prior to the nuclear transfer. The numbers of reconstructed and parthenogenetic embryos transferred were $98{\pm}35.2$ and $145{\pm}11.2$, respectively. The pregnancy and delivery rate were 3/5 (60%) and 2/5 (40%). One healthy SLA homotype-defined SCNT KNP was successfully generated. The recipient-based individual cloning efficiency ranged from 0.65 to 1.08%. Taken together, it can be postulated that the methodological establishment of the production of SLA homotype-defined cloned KNP can be applied to the generation of transgenic cloned KNP as model animals for human disease and xenotransplantation researches.

• Journal of The Korean Society of Agricultural Engineers
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• v.63 no.5
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• pp.63-71
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• 2021

Windbreak forests, which have a windproof effect against strong winds, are known to be effective in reducing the spread of odors and dust emitted from livestock farms. The effect of reducing the spread of odors and dust can be estimated through numerical models such as computational fluid dynamics, which require aerodynamic coefficients of the windbreaks for accurate prediction of their performance. In this study, we aimed to evaluate the aerodynamic coefficients, Co, C₁, C₂, and α, of two windbreaks, Thuja occidentalis and a mesh net, through wind tunnel experiments. The aerodynamic coefficients were derived by the relation between the incoming wind speed and the pressure loss due to the windbreaks which was measured by differential pressure sensors. In order to estimate the change in the aerodynamic coefficient concerning various leaf density, the experiments were conducted repeatedly by removing the leaves gradually in various stages. The results showed that the power law regression model more suitable for coefficient evaluation compared to the Darcy-Forchheimer model.

• Korean Journal of Agricultural Science
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• v.49 no.3
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• pp.431-440
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• 2022

Hanwoo cattle are a unique and historical breed in Korea that have been genetically improved and maintained by the national evaluation and selection system. The aim of this study was to provide information that can help improve the accuracy of the estimated breeding values in Hanwoo cattle by showing the difference between the imputation reference chip platforms of genomic data and the scaling factor of the genetic relationship matrix (GRM). In this study, nine sets of data were compared that consisted of 3 reference platforms each with 3 different scaling factors (-0.5, 0 and 0.5). The evaluation was performed using MTG2.0 with nine different GRMs for the same number of genotyped animals, pedigree, and phenotype data. A five multi-trait model was used for the evaluation in this study which is the same model used in the national evaluation system. Our results show that the Hanwoo custom v1 platform is the best option for all traits, providing a mean accuracy improvement by 0.1 - 0.3%. In the case of the scaling factor, regardless of the imputation chip platform, a setting of -1 resulted in a better accuracy increased by 0.5 to 1.6% compared to the other scaling factors. In conclusion, this study revealed that Hanwoo custom v1 used as the imputation reference chip platform and a scaling factor of -0.5 can improve the accuracy of the estimated breeding value in the Hanwoo population. This information could help to improve the current evaluation system.

• Korean Journal of Poultry Science
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• v.43 no.1
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• pp.1-14
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• 2016

Prediction of growth patterns of commercial chicken strains is important. It can provide visual assessment of growth as function of time and prediction body weight (BW) at a specific age. The aim of current study is to compare the three nonlinear functions (i.e., Logistic, Gompertz, and von Betalanffy) for modeling the growth of twenty five commercial Korean native chicken (KNC) strains reared under a battery cage system until 32 weeks of age and to evaluate the three models with regard to their ability to describe the relationship between BW and age. A clear difference in growth pattern among 25 strains were observed and classified in to the groups according to their growth patterns. The highest and lowest estimated values for asymptotic body weight (C) for 3H and 5W were given by von Bertalanffy and Logistic model 4629.7 g for 2197.8 g respectively. The highest estimated parameter for maturating rate (b) was given by Logistic model 0.249 corresponds to the 2F and lowest in von Bertalanffy model 0.094 for 4Y. According to the coefficient of determination ($R^2$) and mean square of error (MSE), Gompertz and von Bertalanffy models were suitable to describe the growth of Korean native chicken. Moreover, von Bertalannfy model was well described the most of KNC growth with biologically meaningful parameter compared to Gompertz model.

• Journal of Korean Medicine Rehabilitation
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• v.26 no.2
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• pp.75-83
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• 2016

Objectives This study is to review the effect of pharmacopuncture on treatment of osteoporosis in animal models reported in korean domestic journals. Methods The databases (Koreantk, KISS, NDSL) were searched with term as osteoporosis, and animal study reports on osteoporosis with pharmacopuncture were reviewed. Animal model, intervention, and osteoporosis indicator were extracted. Results 22 articles were reviewed. 11 studies used ddy mouse and 9 studies used SD rat. 20 studies used ovariectomy to induce osteoporosis. 21 studies used simple pharmacopuncture. Cervi pantotrichum cornu was most frequently used pharmacopuncture and Umgok (KI10) was most frequently used acupuncture point. Each study shows significant changes of osteoporosis indicators. Conclusions Pharmacopuncture is expected to be a positive effect on osteoporosis.