• 한국산학기술학회논문지
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• 제17권11호
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• pp.114-127
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• 2016

최근 들어 글로벌 경제는 국가 간 경쟁에서 지역 기반 경쟁으로 변모하고 있다. 이 같은 변화 속에 지역공간에 기반한 지식생산과 활용이 강조되고 있다. 우리나라도 고급 과학기술인재를 양성하고 지역산업을 육성한다는 목적 하에 KAIST를 비롯한 5개 과학기술특성화대학을 대전, 대구, 광주, 포항, 울산 지역에 설립한 바 있다. 이들 과학기술특성화대학은 국내 최고 수준의 연구역량과 교육여건을 보유하고 있으며 일반대학과 비교해 우수한 연구성과를 창출하고 있다고 평가된다. 하지만 이들이 설립의 목적과는 달리 우수 연구거점으로서의 역할에 중점을 두었고, 지역혁신 거점으로서 역할은 미흡하다는 지적도 있다. 이 같은 문제의식을 바탕으로 본 연구에서는 과학기술특성화대학의 성과를 Mode 1 성과와 Mode 2 성과로 구분하고 일반대학과 비교함으로써 이들 특성화대학이 설립목적에 부합하며 동시에 지역혁신에 기여하고 있는지를 실증분석 하고자 하였다. 분석결과, 특성화대학은 Mode 1 성과에 있어 일반대학에 비해 높게 나타났으나 Mode 2 성과는 이들에 비해 오히려 낮은 것으로 나타났다. 또한 학과의 구성이나 연구 분야에 있어서도 대학별 차별성이 적고, 지역 특화산업과의 연계 정도도 낮음을 확인할 수 있었다. 결론적으로 Mode 2 관점의 지역과 연계성에 있어 분석의 대상으로 삼은 특성화대학이 일반대학에 오히려 못 미치는 성과를 보였고, 그 특성화 정도에 있어 차이점을 확인하기 어려웠다.

• Asia pacific journal of information systems
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• 제9권2호
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• pp.151-168
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• 1999

The objective of this study is to investigate the effects of different meeting modes and task types on the outcomes of group decision making. The hypotheses postulate the potential effects of different meeting modes on appropriation process; different meeting modes on group outcomes; and the appropriation process on group outcomes. A laboratory experiment was conducted. A GSS was developed using Lotus Notes for this experiment. The results provide partial support for the hypotheses derived from the theoretical model. The interaction effects between meeting modes and tasks are not always observed in the analyses. However, groups using a face-to-face meeting mode in negotiation task reach significantly higher levels of perceived outcome quality, of satisfaction with the outcome, and of satisfaction with the process than groups using a dispersed-synchronous meeting mode. It suggests that a face-to-face meeting mode can enhance the effectiveness of groups working on a negotiation task such as stakeholder analysis. Furthermore, the manner in which groups appropriate the technology significantly influence the group performance. The results support the validity and usefulness of the IRT and the AST as a GSS research framework.

• 한국의류학회지
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• 제30권6호
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• pp.916-927
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• 2006

The purpose of this study was to identify psychological and behavioral outcomes of commitment to apparel brand community by test structural equation model. Subjects of 317 members for 9 selected apparel communities responded the questionnaire in the home-page or in the attached file. The results were as follows: 1) The suggested structural equation mode was accepted by data from apparel brand communities with hish brand strength(${\chi}^2=97.42$, d.f.=89, p=0.25, GFI=0.92, AGFI=0.88, RMR=0.05, NFI=0.94). However, this model wasn't accepted by data kom apparel brand communities with low brand strength. 2) Three types of commitment to brand community(emotional, continuous and normative commitments) influenced brand identification positively and brand identification positively influenced three types of behavioral outcomes(favorable word-of-mouth, co-production and repurchase of brand). Therefore, managements need to develop marketing programs to promote each type of commitment to their's own brand community.

• 성인간호학회지
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• 제26권1호
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• pp.107-116
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• 2014

Purpose: The purpose of this study was to identify the effects of multi-mode simulation learning on critical thinking disposition, on the problem solving process and on clinical competence of nursing students. Methods: A non-equivalent control group with pre-posttest was designed. The participants in this study were 65 students who were enrolled in an emergency and critical nursing course at N university. The treatment group consisted of 33 juniors in 2010 and the control group 32 juniors in 2011. Collected data were analyzed using chi-square, independent t-test, and ANCOVA with the SPSS/WIN 18.0 for Window Program. Results: There were significant increases in problem solving process and clinical competence in the treatment group who participated in the multi-mode simulation learning compared to the control group who did not (t=-2.39, p=.020; F=12.76, p=.001). However, there were no significant differences in critical thinking disposition between the treatment and control group (t=0.40, p=.692). Conclusion: Multi-mode simulation is an effective teaching and learning method to enhance the problem solving process and clinical competence of nursing students. Further exploration is needed to develop and utilize multi-mode simulation for diverse scenarios, depending on emergency nursing educational goals and environments and to develop a universal method to measure outcomes.

• 한국정밀공학회지
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• 제27권6호
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• pp.75-81
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• 2010

The purpose of this study was to investigate the short-term effects of electrical massager on stress-related parameters including heart rate variability (HRV), heart rate (HR) using the photoplethysmogram (PPG) signal with motion artifact correction. Twenty healthy subjects were randomly allocated to receive a 15-min section of three types ((1) resting mode (control group), (2) light massage mode, (3) strong massage mode). Results indicated that self-report, VAS (Visual Analog Scale) significantly decreased for two massage modes after massage except control group. In strong massage mode, it was associated with significant increases in HF, but significant decreases in LF and LH/HF ratio compared with the light massage mode. For all outcomes, similar changes were not observed in the control group. Also, the result founded that mean HR of all groups decrease. We conclude that electrical massager reduces perceived stress and improves adaptive autonomic response to stress in healthy adults.

• Journal of Chest Surgery
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• 제54권5호
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• pp.348-355
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• 2021

Background: Congenital diaphragmatic hernia (CDH) is a rare disease often requiring mechanical ventilation after birth. In severe cases, extracorporeal membrane oxygenation (ECMO) may be needed. This study analyzed the outcomes of patients with CDH treated with ECMO and investigated factors related to in-hospital mortality. Methods: Among 254 newborns diagnosed with CDH between 2008 and 2020, 51 patients needed ECMO support. At Asan Medical Center, a multidisciplinary team approach has been applied for managing newborns with CDH since 2018. Outcomes were compared between hospital survivors and nonsurvivors. Results: ECMO was established at a median of 17 hours after birth. The mean birth weight was 3.1±0.5 kg. Twenty-three patients (23/51, 45.1%) were weaned from ECMO, and 16 patients (16/51, 31.4%) survived to discharge. The ECMO mode was veno-venous in 24 patients (47.1%) and veno-arterial in 27 patients (52.9%). Most cannulations (50/51, 98%) were accomplished through a transverse cervical incision. No significant between-group differences in baseline characteristics and prenatal indices were observed. The oxygenation index (1 hour before: 90.0 vs. 51.0, p=0.005) and blood lactate level (peak: 7.9 vs. 5.2 mmol/L, p=0.023) before ECMO were higher in nonsurvivors. Major bleeding during ECMO more frequently occurred in nonsurvivors (57.1% vs. 12.5%, p=0.007). In the multivariate analysis, the oxygenation index measured at 1 hour before ECMO initiation was identified as a significant risk factor for in-hospital mortality (odds ratio, 1.02; 95% confidence interval, 1.01-1.04; p=0.05). Conclusion: The survival of neonates after ECMO for CDH is suboptimal. Timely application of ECMO is crucial for better survival outcomes.

• Journal of Chest Surgery
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• 제55권3호
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• pp.225-232
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• 2022

Background: Pulmonary lobectomy is the standard of care for the treatment of early-stage non-small cell lung cancer. This study investigated the rate of utilization of supplemental anesthesia in patients undergoing video-assisted thoracoscopic surgery (VATS) or open lobectomy using a national database and assessed the effect of regional block (RB) on postoperative outcomes. Methods: Patients who underwent lobectomy for lung cancer between 2014-2019 were identified in the American College of Surgeons National Surgical Quality Improvement Program. The patients' primary mode of anesthesia and supplemental anesthesia were recorded. Preoperative characteristics and postoperative outcomes were compared between 2 surgical groups: those who underwent general anesthesia (GA) alone versus GA with RB. Multivariable regression analyses were performed on the outcomes of interest. Results: In total, 13,578 patients met the study criteria, with 87% undergoing GA and the remaining 13% receiving GA and RB. The use of neuraxial anesthesia decreased over the years, while RB use increased up to 20% in 2019. Age, body mass index, and preoperative comorbidities were comparable between groups. Patients who underwent VATS were more likely to receive RB than those who underwent thoracotomy. RB was most often utilized by thoracic surgeons. An adjusted analysis showed that RB use was associated with shorter hospital stays and a reduced likelihood of prolonged length of stay, but a higher rate of surgical site infections (SSIs). Conclusion: In a large surgical database, there was underutilization of supplemental anesthesia in patients undergoing lobectomy for lung cancer. RB utilization was associated with a shorter length of hospital stay and an increase in SSI incidence.

• Journal of Chest Surgery
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• 제57권2호
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• pp.195-204
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• 2024

Background: Extracorporeal membrane oxygenation (ECMO) is an intervention for severe heart and lung failure; however, it poses the risk of complications, including gastrointestinal bleeding (GIB). Comprehensive analyses of GIB in patients undergoing ECMO are limited, and its impact on clinical outcomes remains unclear. Methods: This retrospective study included 484 patients who received venovenous and venoarterial ECMO between January 2015 and December 2022. Data collected included patient characteristics, laboratory results, GIB details, and interventions. Statistical analyses were performed to identify risk factors and assess the outcomes. Results: GIB occurred in 44 of 484 patients (9.1%) who received ECMO. Multivariable analysis revealed that older age (odds ratio [OR], 1.04; 95% confidence interval [CI], 1.01-1.06; p=0.0130) and need to change the ECMO mode (OR, 3.74; 95% CI, 1.75-7.96; p=0.0006) were significant risk factors for GIB, whereas no association was found with antiplatelet or systemic anticoagulation therapies during ECMO management. Half of the patients with GIB (22/44, 50%) underwent intervention, with endoscopy as the primary modality (19/22, 86.4%). Patients who underwent ECMO and developed GIB had higher rates of mortality (40/44 [90.9%] vs. 262/440 [59.5%]) and ECMO weaning failure (38/44 [86.4%] vs. 208/440 [47.3%]). Conclusion: GIB in patients undergoing ECMO is associated with adverse outcomes, including increased risks of mortality and weaning failure. Even in seemingly uncomplicated cases, it is crucial to avoid underestimating the significance of GIB.

• Journal of Yeungnam Medical Science
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• 제35권2호
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• pp.156-164
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• 2018

Environmental contaminants are one of the important causal factors for development of various human diseases. In particular, the perinatal period is highly vulnerable to environmental toxicants and resultant dysregulation of fetal development can cause detrimental health outcomes potentially affecting life-long health. Perfluoroalkyl compounds (PFCs), emerging environmental pollutants, are man-made organic molecules, which are widely used in diverse industries and consumer products. PFCs are non-degradable and bioaccumulate in the environment. Importantly, PFCs can be found in cord blood and breast milk as well as in the general population. Due to their physicochemical properties and potential toxicity, many studies have evaluated the health effects of PFCs. This review summarizes the epidemiological and experimental studies addressing the association of PFCs with neurotoxicity and immunotoxicity. While the relationships between PFC levels and changes in neural and immune health are not yet conclusive, accumulative studies provide evidence for positive associations between PFC levels and the incidence of attention deficit hyperactivity disorder and reduced immune response to vaccination both in children and adults. In conclusion, PFCs have the potential to affect human health linked with neurological disorders and immunosuppressive responses. However, our understanding of the molecular mechanism of the effects of PFCs on human health is still in its infancy. Therefore, along with efforts to develop methods to reduce exposure to PFCs, studies on the mode of action of these chemicals are required in the near future.

• 여성건강간호학회지
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• 제18권3호
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• pp.209-222
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• 2012

Purpose: The purpose of this study was to determine whether upright position is effective in labor through systematic review in randomized controlled trials. Methods: We established the PICO (Patient-Intervention-Comparator-Outcome) strategy, and reviewed 282 literatures from national and international electronic databases, and finally selected 9 references based on inclusion and exclusion criteria. We evaluated the quality of references and carried out a meta-analysis. Results: The maternal outcomes showed that the duration of their second-stage labor was 2.29 minutes shorter than that of the women in the recumbent position, and were less likely to have episiotomy. The other outcomes, including the mode of delivery, blood loss, hemoglobin level, use of oxytocin, use of analgesics, and perineal laceration, did not differ between the groups. The fetal heart rate abnormality occurred less than in the control group. The Apgar scores of the groups did not differ. Conclusion: There is evidence that an upright position in the second stage of labor reduces the duration of the second stage of labor, the incidence of episiotomy, and an abnormal fetal heart rate.