• Asian Pacific Journal of Cancer Prevention
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• 제14권8호
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• pp.4693-4697
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• 2013

Background: Malignant transformation arising in mature cystic teratoma (MCT) is one of the most serious complications of MCT. Squamous cell carcinoma is the most common malignant change. Some clinical findings such as advanced age group and large tumor size are significant risk factors of malignant transformation. This study was conducted in order to evaluate characteristics, cell types, treatment and outcome of malignant transformation arising from dermoid cysts in our institution. Materials and Methods: A retrospective chart review was performed. General characteristics, operative data, procedure, operative finding and operative outcome were analyzed. Statistical assessment was performed with SPSS version 17.0, using mean, mode, median and percentage to describe those data. Results: During the 10 years period, 11 cases of malignant transformation from a total of 753 cases (1.46% incidence) of MCT were reviewed. Mean age of the patients was 41.2 years (SD 4.34, range 24-70). The most common presenting symptom was a palpable mass (8 cases; 72.7%). Primary surgical staging was performed in 4 patients (36.4%). Re-staging was conducted in the other 4. Complete cytoreduction was obtained in 45.5% (5 cases) and optimal surgical resection was obtained in 36.4% (4 cases). Mean tumor size was 14.1 cm. (SD 1.55, range 6-20). Squamous cell carcinoma was found in 36.4% (4 cases) and mucinous cancer in the other 4. More than half of them were stage Ia (54.5%, 6 cases). All patients whose stage more than Ia received chemotherapy (45.5%). Mean disease free survival was 5.53 years (1.32, 0.3-10). Conclusion: According to our study, the incidence of malignant transformation was consistent with previous studies. The common malignant transformation histologic types are both squamous and mucinous carcinoma which differed from previous reports. Early detection for early stage disease and optimal surgery are important for long term survival.

• 대한인간공학회지
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• 제36권1호
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• pp.9-21
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• 2017

Objective: The objective of this study is to understand the effect of angle and curvature of push-return switches, which are external factors in the operation environment inside the cars, on the feel of operation and to propose optimum alternatives. Background: Customers' needs for products are changing from functional and performance aspects to customer-led type where customers can reflect on their needs on the products. The operation inside cars is executed by HMI. The push-return switch is utilized as the most intuitive mode of HMI; therefore, this push-return switch, which is widely used, has to be developed by assessing the preference and satisfaction of the customer. Method: The angle and curvatures, which are external factors that affect the feel of operation, are drawn through surveying the preceding research literatures. The stages to construct alternatives in experiments are as follows: (1) the tactile switch is replaced after dismantling the switch assembly to evaluate the internal characteristics proposed by preceding researches, (2) a drawing is prepared by using a design software, is printed using 3D printer, and then it is attached on the switch assembly, and (3) evaluation for satisfaction of operation is carried out by using a driving simulator. Results: Both the angle and curvature that are external factors of switch significantly affect the feel of operation. However, interaction between the two factors is found insignificant. Therefore, an optimum alternative is proposed considering the experimental outcomes. Conclusion: This study evaluates the satisfaction in operation that affects the feel of operation environment inside the cars. Based on the study results, a guideline for switch design in the center fascia is proposed. Application: This study is expected to be used as basic data for designing automotive switches, as well as switches in the industries similar with the operation environments of cars.

• 대한가정학회지
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• 제34권4호
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• pp.327-343
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• 1996

The objective of this study were 1) to determine the stages of concern of HE teachers about the practical problem-based curriculum approach, as illustrated by the Ohio's Work and Family Life Curriculum (W&FLC); 2) to determine the relationships between home economics (HE) teacher's stages of concern about W&FLC and personal and professional characteristics of HE teachers; and 3) to determine aspects of interest about the practical problem-based curriculum approach, such as the Ohio W&FLC. Respondents in this study were 225 HE teachers. The data were collected during the in-service teacher training sessions after presentation about W&FLC. Concerns Based Adoption Model (CBAM) was modified to provide a conceptual framework for this study. Frequencies, SD, mean, mode, range were used to determine the stages of concern of HE teachers. To determine the relationships between stages of concerns and personal and professional characteristics of HE teachers, coefficient of Chi-Square contingency tables was used. Content analysis was used to determine aspects of interest about the practical problem-bsed curriculum approach, such as W&FLC. The median of the stages of HE teachers' concerns about W&FLC was Stage 1, Information Stage. About 60% of HE teachers were interested in learning more details about W&FLC. Chi-square revealed no statistically significant relationships between stages of concerns about W&FLC and characteristics of HE teachers. Content analysis was used to determine aspects of interest about W&FLC of HE teachers. Nine categories were found: content, teaching strategies, implementation of the curriculum, philosophical framework, how to adopt W&FLC, resource materials, students' outcomes, in-service teacher training, and HE teacher organization. The majority of HE teachers were interested in relationships with family and others, resource management, family relationships, personal development, communication skill, family life, creating a self-identity, life planning, roles of family members, homemaking management, child care, and parenting.

• Journal of Power Electronics
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• 제19권1호
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• pp.265-277
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• 2019

The application of shunt active power filters (S-APFs) is considered to be the most popular approach for harmonic compensation due to its high simplicity, ease of installation and efficient control. Its functionality mainly depends upon the rapidness and precision of its internally built control algorithms. A S-APF is generally operated in the current controlled mode (CCM) with the detection of harmonic load current. Its operation may not be appropriate for the distributed power generation system (DPGS) due to the wide dispersion of nonlinear loads. Despite the fact that the voltage detection based resistive-APF (R-APF) appears to be more appropriate for use in the DPGS, the R-APF experiences poor performance in terms of mitigating harmonics and parameter tuning. Therefore, this paper introduces a direct harmonic voltage detection based control approach for the S-APF that does not need a remote harmonic load current since it only requires a local point of common coupling (PCC) voltage for the detection of harmonics. The complete design procedure of the proposed control approach is presented. In addition, experimental results are given in detail to validate the performance and superiority of the proposed method over the conventional R-APF control. Thus, the outcomes of this study approve the predominance of the discussed strategy.

• Advances in nano research
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• 제14권4호
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• pp.363-373
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• 2023

A novel type of steel fiber with a rounded-end shape is presented to improve the bonding behavior of fibers with Carbon Nanotubes (CNT)-reinforced Ultra-High Performance Concrete (UHPC) matrix. For this purpose, by performing a parametric study and using the nonlinear finite element method, the impact of geometric characteristics of the fiber end on its bonding behavior with UHPC has been studied. The cohesive zone model investigates the interface between the fibers and the cement matrix. The mechanical properties of the cohesive zone model are determined by calibrating the finite element results and the experimental fiber pull-out test. Also, the results are evaluated with the straight steel fibers outcomes. Using the novel presented fibers, the bond strength has significantly improved compared to the straight steel fibers. The new proposed fibers increase bond strength by 1.1 times for the same diameter of fibers. By creating fillet at the contact area between the rounded end and the fiber, bond strength is significantly improved, the maximum fiber capacity is reachable, and the pull-out occurs in the form of fracture and tearing of the fibers, which is the most desirable bonding mode for fibers. This also improves the energy absorbed by the fibers and is 4.4 times more than the corresponding straight fibers.

• Clinical Nutrition Research
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• 제12권2호
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• pp.91-98
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• 2023

Adequate nutritional support is crucial in preventing complications and improving outcomes in critically ill patients. Extracorporeal membrane oxygenation (ECMO) is a mode of supportive care for patients with respiratory and/or cardiac failure. ECMO patients frequently exhibit a hypermetabolic state characterized by protein catabolism and insulin resistance, which can lead to malnutrition. Nutritional therapy is a vital component of intensive care, but its optimal administration for ECMO patients is unknown. This case report aims to provide insights into effective nutritional management for critically ill patients undergoing ECMO therapy. The patient was a 72-year-old male with a history of gastric and lung cancer who underwent a lobectomy complicated by bronchopleural fistula, postoperative bleeding, pneumonia, and acute respiratory distress syndrome (ARDS). The patient's nutritional status was assessed indicating a high risk of malnutrition, using the modified Nutrition Risk in the Critically Ill (mNUTRIC) Score. Nutritional support was administered based on the recommendations of European Society for Clinical Nutrition and Metabolism (ESPEN) and the American Society for Parenteral and Enteral Nutrition (ASPEN), with energy requirements set at 25-30 kcal/kg/d and protein requirements set at 1.2-2.0 g/kg/day. The patient received parenteral nutrition until the enteral nutrition target amount was reached, with zinc supplements for wound healing. The study highlights the need for further research on proactive and effective nutritional support for ECMO patients to improve compliance and prognosis.

• Journal of Korean Medical Science
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• 제33권43호
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• pp.277.1-277.10
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• 2018

Background: To examine survival rates and renal function after partial nephrectomy (PN) and radical nephrectomy (RN) in patients with chronic kidney disease (CKD). Methods: We studied 4,332 patients who underwent PN or RN for pathological T1a-T2N0M0 renal cell carcinoma from 1988 to 2014. Patients were divided into two subgroups of CKD stage I-II and stage III. Kidney function, and survival outcomes were compared between groups. Results: We included 1,756 patients with CKD I-II and 276 patients with CKD III in the final pair-matched analysis. Kidney function was significantly better preserved in the PN than in the RN group among all patients. However, the beneficial effect of PN on kidney function gradually disappeared over time in CKD III patients. The 5-year overall survival (OS) rates after PN and RN differed in patients with CKD I-II disease (99.4% vs. 96.5%, respectively, P = 0.015). The 5-year OS rates after surgery were not affected by mode of nephrectomy in CKD III patients (97.8% vs. 93.5%, P = 0.103). The 5-year cancer-specific survival rates did not differ between treatment groups in all CKD stage. Cox hazard analysis showed that the operative method was a significant factor for OS in CKD I-II patients (hazard ratio [HR], 0.320; confidence interval [CI], 0.122-0.840; P = 0.021). However, PN was not beneficial in terms of OS in CKD III patients (HR, 0.395; CI, 0.086-1.172; P = 0.117). Conclusion: PN is associated with a higher OS rate and better kidney function in patients with preoperative CKD stage I and II, but not in those with CKD stage III.

• Asian Pacific Journal of Cancer Prevention
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• 제14권7호
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• pp.4061-4066
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• 2013

The extranodal natural killer/T-cell lymphoma (ENKTL) shows high local or systemic failure rates when radiotherapy (RT) is taken as the primary treatment, suggesting a role for chemotherapy (CT) added to RT for this disease. However, the appropriate mode of combined modality therapy (CMT) has not been fully defined. A total of one hundred and twenty-one patients with ENKTL receiving sandwich CT with RT were reviewed between January 2003 and August 2012. The primary endpoints were the response rate, progression-free survival (PFS), overall survival (OS), and the relapse rate. After the initial CT, there were 84 (69.4%) patients in CR, 22 (18.2%) patients in PR, 9 (7.4%) patients in SD, and 6 (5%) patients in PD, respectively. At the end of RT, the CR, PR, SD, and PD rates for all patients were 90.9% (n=110), 1.7% (n=2), 4.1% (n=5), and 3.3% (n=4), respectively. After a median follow-up of 42.3 months (3.5~112.3 months), the 5-year PFS was 74.7% (95% CI 70.4%~79.0%), and 5-year OS was 77.3% (95% CI 67.9%~86.7%). Disease progression was documented in 25 (20.7%) patients. The rates of systemic failure, local failure, and regional failure were 18.2%, 5.8%, 1.7%, respectively. Twenty death events (16.5%) were observed for the entire group of patients (18 deaths related to PD). Furthermore, CR to the initial CT and low Korean Prognostic Index (KPI) can independently predict long PFS and OS. The sandwich CMT achieved an excellent outcome for localized ENKTL with acceptable toxicity. We recommend it can be applied as the optimal choice for localized ENKTL.

• 한국ITS학회 논문지
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• 제13권3호
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• pp.10-24
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• 2014

최근 저탄소 녹색정책이 활발히 이루어지면서 자전거 이용자가 증가하고 있다. 효과적인 자전거교통 관련 제어 정보제공 계획수립을 위해서 모니터링은 필수적이며, 개별자전거의 주행 패턴을 미시적으로 수집하고 처리 가공하여 트래킹기반 자전거 모니터링 할 수 있는 기술이 요구된다. 따라서 본 연구에서는 GPS속도계 등 센서를 장착하여 개별 자전거의 주행자료 수집이 가능한 프로브자전거의 자료처리 및 활용 방안에 관한 내용을 제안하였다. 본 연구에서는 수집된 프로브자전거의 자료를 유용한 정보로 가공하기 위해 1차적으로 전처리 하는 과정을 제시하였으며, 수집된 원시자료의 품질을 평가하고, 1차 가공을 통해 향상된 품질의 자료를 센터에서 관리 할 수 있도록 하는 일련의 과정을 제시하였다. 자료가 수집되게 되면 첫 번째로 자료 활용의 목적에 맞게 보간 과정을 거치게 된다. 두 번째 단계에서는 수집된 다수의 자료를 이용하여 통계적인 방법을 통해 데이터의 사용가치 향상을 위한 품질을 평가하는 과정을 거치게 된다. 세 번째 단계에서는 두 번째 단계에서 산출된 품질 기준을 향상시키기 위한 방법으로 스무딩 과정을 거치게 된다. 스무딩 된 데이터는 교통정보 센터에 저장되며, 자전거 시스템 모니터링 및 정보 생성을 위한 기초 자료로 활용된다. 본 연구에서 제시한 프로브 자전거 자료처리 기법은 현장에서 수집된 원시자료의 품질을 평가하고 1차 가공하는 과정의 가이드라인으로 활용될 수 있으며, 향후 자전거 시스템 모니터링 기법 개발의 기초 연구가 될 것으로 판단된다.

• Korean Circulation Journal
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• 제54권2호
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• pp.63-75
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• 2024

Background and Objectives: Evidence regarding the efficacy and safety of intracardiac echocardiography (ICE) for guidance during transcatheter aortic valve replacement (TAVR) is limited. This study aimed to compare the clinical efficacy and safety of ICE versus transesophageal echocardiography (TEE) for guiding TAVR. Methods: This prospective cohort study included patients who underwent TAVR from August 18, 2015, to June 31, 2021. Eligible patients were stratified by echocardiographic modality (ICE or TEE) and anesthesia mode (monitored anesthesia care [MAC] or general anesthesia [GA]). Primary outcome was the 1-year composite of all-cause mortality, rehospitalization for cardiovascular cause, or stroke, according to the Valve Academic Research Consortium-3 (VARC-3) definition. Propensity score matching was performed, and study outcomes were analyzed for the matched cohorts. Results: Of the 359 eligible patients, 120 patients were matched for the ICE-MAC and TEEGA groups, respectively. The incidence of primary outcome was similar between matched groups (18.3% vs. 20.0%; adjusted hazard ratio, 0.94; 95% confidence interval [CI], 0.53-1.68; p=0.843). ICE-MAC and TEE-GA also had similar incidences of moderate-to-severe paravalvular regurgitation (PVR) (4.2% vs. 5.0%; adjusted odds ratio, 0.83; 95% CI, 0.23-2.82; p=0.758), new permanent pacemaker implantation, and VARC-3 types 2-4 bleeding. Conclusions: ICE was comparable to TEE for guidance during TAVR for the composite clinical efficacy outcome, with similar incidences of moderate-to-severe PVR, new permanent pacemaker implantation, and major bleeding. These results suggest that ICE could be a safe and effective alternative echocardiographic modality to TEE for guiding TAVR.