• 제목/요약/키워드: Mixed-effect model

Search Result 568, Processing Time 0.031 seconds

Meta-analysis of the effects on family life education for couples in Korea (한국 부부교육 프로그램의 효과에 대한 메타분석)

  • Lee, Eun-yeong;Jang, Jin-Kyung
    • Journal of Family Relations
    • /
    • v.22 no.4
    • /
    • pp.181-204
    • /
    • 2018
  • Objectives: The aim of this study is to integrate the results of the previous studies from 1900 to 2016 according to the types of dependent variables individually and statistically to obtain the results of the overall level of the marital education program I need to figure it out. In other words, the general and valid study on the overall effectiveness of the marriage education program will lead to more concluded conclusions and draw up an integrated and holistic conclusion about the effectiveness of the marriage education program. Method: The purpose of this study was to investigate the effect of married couples' education program on married couples' education program. The results of this study are as follows. First, Comprehensive Meta-Analysis. In other words, funnel plot, forest plot, and trim & fill were used to analyze all the variables related to the education of the couple, and homogeneity test After choosing an analytical model for the analysis, we calculated the 'standardized mean difference' effect size (d) that can compare different individual studies through the analytical model. The results of this study are as follows. Results: The purpose of this study was to investigate the overall effect size of domestic couples education programs after 1990, and to investigate the effect sizes of dependent variable types and program - related variables. First, the total effect size of the domestic marriage education program was close to the level of the large effect size and had a substantial and preventive effect. Self-esteem, communication, marital adjustment, emotion, and self control have a substantial and prophylactically significant change depending on the type of subordinate variables related to the marital education program But there was no change in origin family and life satisfaction. Third, as a result of the categorization of the dependent variable categorization of the Korean couple education program, it was found that the marital relations of the participant in the individual inner and the marital relations The effect was significant enough to change. Fourth, Korean couple education program was most effective when mixed age couples were participated in various family life cycle. Conclusions: Based on the results of this study, it is necessary to study more deeply about marital education program effect of marriage education for various special groups such as married couples who are in a crisis of divorce, . It also means that the results of the research for the last 30 years from 1900 to 2016 were comprehensively and systematically summarized through meta - analysis. The results of this study provide information on how to provide the most effective couples education programs for practitioners in the field. The result of this study will be the data of judgment about how to organize the marital education program for people of any ages and characteristics in the future.

Potential of the Quantitative Trait Loci Mapping Using Crossbred Population

  • Yang, Shulin;Zhu, Zhengmao;Li, Kui
    • Asian-Australasian Journal of Animal Sciences
    • /
    • v.18 no.12
    • /
    • pp.1675-1683
    • /
    • 2005
  • In the process of crossbreeding, the linkage disequilibria between the quantitative trait loci (QTL) and their linked markers were reduced gradually with increasing generations. To study the potential of QTL mapping using the crossbred population, we presented a mixed effect model that treated the mean allelic value of the different founder populations as the fixed effect and the allelic deviation from the population mean as random effect. It was assumed that there were fifty QTLs having effect on the trait variation, the population mean and variance were divided to each QTL in founder generation in our model. Only the additive effect was considered in this model for simulation. Six schemes (S1-S6) of crossbreeding were studied. The selection index was used to evaluate the synthetic breeding value of two traits of the individual in the scheme of S2, S4 and S6, and the individuals with high selection index were chosen as the parents of the next generation. Random selection was used in the scheme of S1, S3 and S5. In this study, we premised a QTL explained 40% of the genetic variance was located in a region of 20 cM by the linkage analysis previously. The log likelihood ratio (log LR) was calculated to determine the presence of a QTL at the particular chromosomal position in each of the generations from the fourth to twentieth. The profiles of log LR and the number of the highest log LR located in the region of 5, 10 and 20 cM were compared between different generations and schemes. The profiles and the correct number reduced gradually with the generations increasing in the schemes of S2, S4 and S6, but both of them increased in the schemes of S1, S3 and S5. From the results, we concluded that the crossbreeding population undergoing random selection was suitable for improving the resolution of QTL mapping. Even experiencing index selection, there was still enough variation existing within the crossbred population before the fourteenth generation that could be used to refine the location of QTL in the chromosome region.

Effect of cyclic loading on axial displacement of abutment into implant with internal tapered connection: a pilot study (내측연결형 임플란트에 체결한 지대주의 수직침하에 대하여 반복하중이 미치는 영향)

  • Seol, Hyon-Woo;Heo, Seong-Joo;Koak, Jai-Young;Kim, Seong-Kyun;Han, Chong-Hyun
    • The Journal of Korean Academy of Prosthodontics
    • /
    • v.51 no.4
    • /
    • pp.315-322
    • /
    • 2013
  • Purpose: To evaluate the axial displacement of implant-abutment assembly after cyclic loading in internal tapered connection system. Materials and methods: External butt-joint connection implant and internal tapered connection implant were connected with three types of abutment for cement-retained prostheses, i.e. external type abutment (Ext group), internal tapered 1-piece abutment (Int-1 group), and internal tapered 2-piece abutment (Int-2 group). For each group, 7 implants and abutments were used. The implantabutments assemblies were clamped into the implant holder for vertical loads. A dynamic cyclic loading was applied for $150{\pm}10N$ at a frequency of 4 Hz. The amount of axial displacement of the abutment into the implant was calculated at each cycle of 0, 5, 10, 50, 100, 1,000, 5,000, and 10,000. A repeated measures analysis of variance (ANOVA) for the overall effect of cyclic loading and the pattern analysis by linear mixed model were used for statistical analysis. Differences at P<.05 were considered statistically significant. Results: The mean axial displacement after 10,000 cycles were $0.714{\pm}0.488{\mu}m$ in Ext group, $5.286{\pm}1.604{\mu}m$ in Int-1 group, and $11.429{\pm}1.902{\mu}m$ in Int-2 group. In the pattern analysis, Int-1 and Int-2 group showed continuous axial displacement at 10,000 cycles. There was no declining pattern of axial displacement in the Ext group. Conclusion: The pattern of linear mixed model in Ext group showed no axial displacement. There were continuous axial displacements in abutment-implant assemblies in the Int-1 and Int-2 group at 10,000 cycles. More axial displacement was found in Int-2 group than in Int-1 group.

Genome-wide association study of carcass weight in commercial Hanwoo cattle

  • Edea, Zewdu;Jeoung, Yeong Ho;Shin, Sung-Sub;Ku, Jaeul;Seo, Sungbo;Kim, Il-Hoi;Kim, Sang-Wook;Kim, Kwan-Suk
    • Asian-Australasian Journal of Animal Sciences
    • /
    • v.31 no.3
    • /
    • pp.327-334
    • /
    • 2018
  • Objective: The objective of the present study was to validate genes and genomic regions associated with carcass weight using a low-density single nucleotide polymorphism (SNP) Chip in Hanwoo cattle breed. Methods: Commercial Hanwoo steers (n = 220) were genotyped with 20K GeneSeek genomic profiler BeadChip. After applying the quality control of criteria of a call rate ${\geq}90%$ and minor allele frequency (MAF) ${\geq}0.01$, a total of 15,235 autosomal SNPs were left for genome-wide association (GWA) analysis. The GWA tests were performed using single-locus mixed linear model. Age at slaughter was fitted as fixed effect and sire included as a covariate. The level of genome-wide significance was set at $3.28{\times}10^{-6}$ (0.05/15,235), corresponding to Bonferroni correction for 15,235 multiple independent tests. Results: By employing EMMAX approach which is based on a mixed linear model and accounts for population stratification and relatedness, we identified 17 and 16 loci significantly (p<0.001) associated with carcass weight for the additive and dominant models, respectively. The second most significant (p = 0.000049) SNP (ARS-BFGL-NGS-28234) on bovine chromosome 4 (BTA4) at 21 Mb had an allele substitution effect of 43.45 kg. Some of the identified regions on BTA2, 6, 14, 22, and 24 were previously reported to be associated with quantitative trait loci for carcass weight in several beef cattle breeds. Conclusion: This is the first genome-wide association study using SNP chips on commercial Hanwoo steers, and some of the loci newly identified in this study may help to better DNA markers that determine increased beef production in commercial Hanwoo cattle. Further studies using a larger sample size will allow confirmation of the candidates identified in this study.

Understanding Complex Design Features via Design Effect Models (설계효과모형을 통한 설계요소의 유용성 이해)

  • Park, Inho
    • The Korean Journal of Applied Statistics
    • /
    • v.28 no.6
    • /
    • pp.1217-1225
    • /
    • 2015
  • Survey research, data is commonly collected through a sample design with complex design features that allow the relative efficiency on the precision of an estimator to be measured using the concept of the design effect compared to simple random sampling as a reference design. This concept is most useful when the design effect can be expressed as a function of various design features. We propose a design effect formula suitable under a stratified multistage sampling by generalizing Gabler et al. (1999, 2006)'s approaches for multistage sampling. Its use can either guide improvement in the design efficiency when in design stage or enable the evaluation of the adopted design features afterwards.

Influence of Specimen Geometries on the Compressive Strength of Lightweight Aggregate Concrete (경량골재 콘크리트의 압축강도에 대한 시험체 기하학적 특성의 영향)

  • Sim, Jae-Il;Yang, Keun-Hyeok
    • Journal of the Korea Concrete Institute
    • /
    • v.24 no.3
    • /
    • pp.333-340
    • /
    • 2012
  • The current study prepared 9 laboratorial concrete mixes and 3 ready-mixed concrete batches to examine the size and shape effects in compression failure of lightweight aggregate concrete (LWC). The concrete mixes were classified into three groups: normal-weight, all-lightweight and sand-lightweight concrete groups. For each concrete mix, the aspect ratio of circular or square specimens was 1.0 and 2.0. The lateral dimension of specimens varied between 50 and 150 mm for each laboratorial concrete mix, whereas it ranged from 50 to 400 mm with an incremental variation of 50 mm for each ready-mixed concrete batch. Test observations revealed that the crack propagation and width of the localized failure zone developed in lightweight concrete specimens were considerably different than those of normal-weight concrete (NWC). In LWC specimens, the cracks mainly passed through the coarse aggregate particles and the crack distribution performance was very poor. As a result, a stronger size effect was developed in LWC than in NWC. Especially, this trend was more notable in specimens with aspect ratio of 2.0 than in specimens with that of 1.0. The prediction model derived by Kim et al. overestimated the size effect of LWC when lateral dimension of specimen is above 150 mm. On the other hand, the modification factors specified in ASTM and CEB-FIP provisions, which are used to compensate for the shape effect of specimen on compressive strength, were still conservative in LWC.

Relationship between Expandability, MacEwan Crystallite Thickness, and Fundamental Particle Thickness in Illite-Smectite Mixed Layers (일라이트-스멕타이트 혼합층광물의 팽창성과 MacEwan 결정자 및 기본입자두께에 관한 연구)

  • 강일모;문희수;김재곤;송윤구
    • Journal of the Mineralogical Society of Korea
    • /
    • v.15 no.2
    • /
    • pp.95-103
    • /
    • 2002
  • The object of this study was to interpret the ralationship between expandability (% $S_{XRD}$), MacEwan crystallite thickness ( $N_{CSD}$), and mean fundamental particle thickness ( $N_{F}$ ) in illite-semctite mixed layer (I-S), quantitatively. This interpretation was extracted from comparison of two structural models (MacEwan crystallite model and fundamental particle model) of I-S mixed layers. In I-S structure, % $S_{XRD}$, $N_{CSD}$, and $N_{F}$ are not independent parameters but are related to each others by particular geometric relations. % $S_{XRD}$ is dependent on $N_{CSD}$ by short-stack effect, whereas, % $S_{XRD}$ and $N_{F}$ have relation to smectite interlayer number (Ns)=( $N_{F-}$1)/(100%/% $S_{XRD-}$ $N_{F}$ . Therefore, % $S_{XRD}$ and $N_{F}$ should satisfy a specific physical condition, 1< $N_{F}$ <100%/% $S_{XRD}$, because $N_{s}$ is positive. Based on this condition, this study suggested % $S_{XRD}$ vs $N_{F}$ diagram which can be used to interpret % $S_{XRD}$, $N_{F}$ , $N_{S}$ , and ordering, quantitatively. The diagram was examined by XRD data for I-S samples from Ceumseongsan volcanic complex, Korea. I-S samples showed that $N_{F}$ departs from the physical upper-limit ( $N_{F}$ =100%/% $S_{XRD}$) with decrease in % $S_{XRD}$. This phenomenon may happen due to decrease of stacking-capability of fundamental particles with their thickening.g.s with their thickening.g.

Hypoglycemic Effect of Fermented Soybean Culture Mixed with Mulberry Leaves on Neonatal Streptozotocin-Induced Diabetic Rats (뽕잎 함유 대두발효물이 신생 당뇨유도쥐에 미치는 혈당강하효과)

  • Hwang, Kyo-Yeol;Kim, Young-Hoon;Cho, Yong-Seok;Park, Young-Shik;Lee, Jae-Yeon;Kang, Kyung-Don;Kim, Keun;Joo, Dong-Kwan;Ahn, Duk-Kyun;Seong, Su-Il
    • Journal of the Korean Society of Food Science and Nutrition
    • /
    • v.37 no.4
    • /
    • pp.452-458
    • /
    • 2008
  • The effect of fermented soybean culture of Bacillus subtilis MORI mixed with mulberry leaves on the lowering the levels of blood glucose and cholesterol was examined using neonatal streptozotocin-induced diabetic (n-STZ) rats. B. subtilis MORI produces 1-deoxynojirimycin (DNJ), an $\alpha$-glucosidase inhibitor. The content of DNJ of soybean fermented culture mixed with mulberry was higher (4.1$\pm$0.0 mg/g dry base) than that (1.5$\pm$0.0 mg/g) of mulberry. The concentration of 50% inhibition (IC50) against rat intestinal $\alpha$-glucosidase of soybean fermented culture mixed with mulberry was $5.6{\pm}0.1{\mu}g$/mL and that of mulberry was $17.0{\pm}0.5{\mu}g$/mL. Experimental groups of diabetic rats were randomly assigned to normal control group (NC group), diabetic control group (DC group) and three diabetic groups fed with DNJ food product. One of the three diabetic groups was M group (60 mg DNJ food product/kg) (DNJ food product containing 30% mulberry) and the other two were MM-60 group (60 mg/kg) and MM-120 group (120 mg/kg) (DNJ-fortified food product containing 30% fermented soybean culture mixed with mulberry leaves). The glucose in serum was significantly decreased in the MM-60 and MM-120 groups fed with DNJ-fortified food product for 4 weeks, compared with DC group. Total cholesterol and triglyceride in serum were also lower in MM-60 and MM-120 groups than the DC group. These results support that the fermented soybean culture of B. subtilis MORI mixed with mulberry leaves improved the metabolism of blood glucose and lipid in the n-STZ rat model.

Thermohydromechanical Behavior Study on the Joints in the Vicinity of an Underground Disposal Cavern (심부 처분공동 주변 절리에서의 열수리역학적 거동변화)

  • Jhin wung Kim;Dae-seok Bae
    • The Journal of Engineering Geology
    • /
    • v.13 no.2
    • /
    • pp.171-191
    • /
    • 2003
  • The objective of this present study is to understand long term(500 years) thermohydromechanical interaction behavior on joints adjacent to a repository cavern, when high level radioactive wastes are disposed of within discontinuous granitic rock masses, and then, to contribute this understanding to the development of a disposal concept. The model includes a saturated discontinuous granitic rock mass, PWR spent nuclear fuels in a disposal canister surrounded with compacted bentonite inside a deposition hole, and mixed bentonite backfilled in the rest of the space within a repository cavern. It is assumed that two joint sets exist within a model. Joint set 1 includes joints of $56^{\circ}$ dip angle, spaced 20m apart, and joint set 2 is in the perpendicular direction to joint set 1 and includes joints of $34^{\circ}$ dip angle, spaced 20m apart. The two dimensional distinct element code, UDEC is used for the analysis. To understand the joint behavior adjacent to the repository cavern, Barton-Bandis joint model is used. Effect of the decay heat from PWR spent fuels on the repository model has been analyzed, and a steady state flow algorithm is used for the hydraulic analysis.

A Study on the Subject Specialization System Model of University Libraries in the 21st Century (21세기 대학도서관의 주제별 자료실 조직모형 연구)

  • Chung, Jae-young;Nam, Tae-Woo
    • Journal of the Korean Society for Library and Information Science
    • /
    • v.38 no.1
    • /
    • pp.173-197
    • /
    • 2004
  • It is searched that 56 out of 185 university libraries(30.2%) has adopted 'subject specialization' organization. This 'subject specialization' emerged when university libraries began to care about their users and services for them more than other factors in planning and structuring their organization. The number of university libraries which try to adopt that organization has been continuously increasing. To settle 'subject specialization' in the university libraries under Korea's proper condition and to maximize its effect, each library should consider one's own conditions and step the reasonable procedure in adopting that system. Considering the similar condition which the university libraries in Korea face such as shortage of material support, 'Mixed Model of subject specialization" is reasonable, which means in whole structure of library function-oriented organization is adopted and in Reference Service, subject specialization is adopted. However, the ideal and final destination of Korea's university libraries is the adoption of 'Full subject specialized model": it can be reached when they are supported by sufficient human resources and good conditions.