• Title/Summary/Keyword: Mixed Sensitivity Problem

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A Clinical Study of Surgically Managed Thyroid Nodule (외과적으로 처치한 갑상선 결절)

  • Hong Kwan-Uye;Lee Myung-Bok;Moon Chul;Kim Ik-Soo
    • Korean Journal of Head & Neck Oncology
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    • v.10 no.2
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    • pp.91-101
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    • 1994
  • Nodular thyroid disease is a common clinical problem. The problem in clinical practice is to distinguish malignant or potentially malignant tumor from harmless nodules. The cases of thyroid nodule surgically managed at Department of General Surgery, Soon Chun Hyang Univ. Hospital during the period Jan. 1985 to July. 1992 were reviewed retrospectively. To assess method of distinguishing malignant from benign lesions of the thyroid gland, we reviewed 162 patients with thyroid nodule. There were 61(37.7%) malignant nodules and 101(62.3%) benign nodules. According to the review, distinguishing the benign from the malignant nodule with history, physical examination, clinical manifestation, and duration of illness was not suggested sufficiently. In ultrasonogram of 73 cases, 57.5% of nodules were solid, 20.6% were cystic, 21.9% were mixed solid and cystic. Of these, 28.5% of the operated solid lesions, 12.5% of the mixed lesions, and only 6.7% of the cystic lesions were malignant. Thyroid scanning of 82 cases revealed cold nodules in 60 patients(73.2%), of which 26 cases were malignant(36.6%) 137 patients underwent fine needle aspiration cytology(FNAC), and these results were as follow: sensitiviey was 70.6%, specificity was 93.0%, false-positive rate was 14.3%, and false-negative rate was 15.8%. 41 patients underwent frozen biopsy, and the results as follow: sensitivity was 80.0%, specificity was 89.7%. Neither scintigraphy nor ultrasonogram has sufficient specificity to distinguish benign from malignant nodule. But FNAC and frozen biopsy have sufficient accuracy to differentiate benign from malignant nodule. In the benign nodules, the most common type of operation was total lobectomy (60.4%). Of the malignant nodules, total thyroidectomy with or without modified radical neck dissection was performed in 30 cases(49.2%). We conclude that the single technique used to determine the differential diagnosis of a thyroid nodule are unrealiable. It is therefore essential to combine all avaiable clinical and laboratory information.

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An Adaptive Feedback Canceller for Fully Implantable Hearing Device Using Tympanic Membrane Installed Microphone (고막이식형 마이크로폰을 위한 이식형 인공중이 적응 피드백 제거기 구현)

  • Kim, Tae Yun;Kim, Myoung Nam;Cho, Jin-Ho
    • Journal of Korea Multimedia Society
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    • v.19 no.2
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    • pp.189-199
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    • 2016
  • Many implantable hearing aids are being developed as alternatives to conventional hearing aids which has inconveniences for use and social stigma that make hearing-impaired people avoid to wear it. Particularly, the fully-implantable middle ear hearing devices (F-IMEHD) are being actively studied for mixed or sensorineural hearing impaired people. In development of F-IMEHD, the most difficult problem is improving the performance of implantable microphone. Recently, Cho et al. have studied the tympanic membrane installed microphone which has better sensitivity and is easier to operate on patient than the microphone implanted under the skin. But, it may cause howling problem due to the feedback signal via oval window and ossicle chain from the transducer on round window in the middle ear cavity, therefore, a feedback canceller is necessary. In this paper, we designed NLMS (normalized least mean square) adaptive feedback canceller for F-IMEHD with tympanic membrane installed microphone and a transducer implemented at round window, and computer simulation was performed to verify its operation. The designed adaptive feedback canceller has a delay filter, a 64 point FIR fixed filter and a 8-tap adaptive FIR filter. Computer simulation of the feedback path is modeled by using the data obtained through human cadaver experiment.

Regional Science and Technology Resource Allocation Optimization Based on Improved Genetic Algorithm

  • Xu, Hao;Xing, Lining;Huang, Lan
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • v.11 no.4
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    • pp.1972-1986
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    • 2017
  • With the advent of the knowledge economy, science and technology resources have played an important role in economic competition, and their optimal allocation has been regarded as very important across the world. Thus, allocation optimization research for regional science and technology resources is significant for accelerating the reform of regional science and technology systems. Regional science and technology resource allocation optimization is modeled as a double-layer optimization model: the entire system is characterized by top-layer optimization, whereas the subsystems are characterized by bottom-layer optimization. To efficaciously solve this optimization problem, we propose a mixed search method based on the orthogonal genetic algorithm and sensitivity analysis. This novel method adopts the integrated modeling concept with a combination of the knowledge model and heuristic search model, on the basis of the heuristic search model, and simultaneously highlights the effect of the knowledge model. To compare the performance of different methods, five methods and two channels were used to address an application example. Both the optimized results and simulation time of the proposed method outperformed those of the other methods. The application of the proposed method to solve the problem of entire system optimization is feasible, correct, and effective.

A Study on the Control of Parallel-Type Inverted Pendulum by $H_\infty$ Control ($H_\infty$제어에 의한 병렬형 도립진자의 제어에 관한 연구)

  • Yang, Joo-Ho;Byun, Jung-Hoan
    • Journal of the Korean Society of Fisheries and Ocean Technology
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    • v.31 no.2
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    • pp.178-189
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    • 1995
  • In this pater, authors derive the state - space equiation about the patallel - type inverted pendulum which is adopted as control object, and constitute the control system by $H_\infty$control theory. The modeling error is unavoidably existed by linearization error, and so on. We regard this modeling error which is determined from the identification through frequency response as unstructured model uncertainty. An augmented state - space equiation with frequency weighting function is constructed for application of the $H_\infty$theory, and the mixed sensitivity problem is considered. The weighting functions are determined in consideration of the model uncertainty and the response of system in frequency region. The $H_\infty$controller is designed by using software package for controller design. From results of response simulation, the control system designed with $H_\infty$theory guarantees low sensitivity for disturbance as well as robustness against the model uncertainties.

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A New Approach for Detection of Gear Defects using a Discrete Wavelet Transform and Fast Empirical Mode Decomposition

  • TAYACHI, Hana;GABZILI, Hanen;LACHIRI, Zied
    • International Journal of Computer Science & Network Security
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    • v.22 no.2
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    • pp.123-130
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    • 2022
  • During the past decades, detection of gear defects remains as a major problem, especially when the gears are subject to non-stationary phenomena. The idea of this paper is to mixture a multilevel wavelet transform with a fast EMD decomposition in order to early detect gear defects. The sensitivity of a kurtosis is used as an indicator of gears defect burn. When the gear is damaged, the appearance of a crack on the gear tooth disrupts the signal. This is due to the presence of periodic pulses. Nevertheless, the existence of background noise induced by the random excitation can have an impact on the values of these temporal indicators. The denoising of these signals by multilevel wavelet transform improves the sensitivity of these indicators and increases the reliability of the investigation. Finally, a defect diagnosis result can be obtained after the fast transformation of the EMD. The proposed approach consists in applying a multi-resolution wavelet analysis with variable decomposition levels related to the severity of gear faults, then a fast EMD is used to early detect faults. The proposed mixed methods are evaluated on vibratory signals from the test bench, CETIM. The obtained results have shown the occurrence of a teeth defect on gear on the 5th and 8th day. This result agrees with the report of the appraisal made on this gear system.

The flexible routing with flex for the fast delivery

  • Park, TaeJoon;Chung, Yerim
    • Journal of the Korea Society of Computer and Information
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    • v.26 no.9
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    • pp.143-153
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    • 2021
  • In this paper, we propose "flexible routing with flex" to provide fast delivery by using the flexible routing for the delivery vehicle and crowd-shipper named flex. To this end, we have introduced an algorithm that can build the delivery plan for delivery vehicles and flexes. The introduced algorithm uses the 2-opt algorithm to construct routes with low complexity and acceptable quality, and the revised saving algorithm to assign customer orders to the flex. The algorithm allows the vehicle and the flex to function complement each other without separating the delivery vehicle from the flex. The experiments consider the 3 different instances named Random, Mixed, Cluster, and show that "the flexible routing with flex" has a better result than "vehicle only". The sensitivity analysis of the flex cost and time penalty shows "the flexible routing with flex" can provide better service not only to the customers who are serviced by flex but also to the customers who are serviced by the delivery vehicle.

Update on Irritable Bowel Syndrome Program of Research

  • Heitkemper, Margaret;Jarrett, Monica;Jun, Sang-Eun
    • Journal of Korean Academy of Nursing
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    • v.43 no.5
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    • pp.579-586
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    • 2013
  • Purpose: This article provides an update and overview of a nursing research program focused on understanding the pathophysiology and management of irritable bowel syndrome (IBS). Methods: This review includes English language papers from the United States, Europe, and Asia (e.g., South Korea) from 1999 to 2013. We addressed IBS as a health problem, emerging etiologies, diagnostic and treatment approaches and the importance of a biopsychosocial model. Results: IBS is a chronic, functional gastrointestinal disorder characterized by recurrent episodes of abdominal pain and alterations in bowel habit (diarrhea, constipation, mixed). It is a condition for which adults, particularly women ages 20-45, seek health care services in both the United States and South Korea. Clinically, nurses play key roles in symptom prevention and management including designing and implementing approaches to enhance the patients' self-management strategies. Multiple mechanisms are believed to participate in the development and maintenance of IBS symptoms including autonomic nervous system dysregulation, intestinal inflammation, intestinal dysbiosis, dietary intolerances, alterations in emotion regulation, heightened visceral pain sensitivity, hypothalamic-pituitary-adrenal dysregulation, and dysmotility. Because IBS tends to occur in families, genetic factors may also contribute to the pathophysiology. Patients with IBS often report a number of co-morbid disorders and/or symptoms including poor sleep. Conclusion: The key to planning effective management strategies is to understand the heterogeneity of this disorder. Interventions for IBS include non-pharmacological strategies such as cognitive behavior therapy, relaxation strategies, and exclusion diets.

Humanitarian Relief Logistics with Time Restriction: Thai Flooding Case Study

  • Manopiniwes, Wapee;Nagasawa, Keisuke;Irohara, Takashi
    • Industrial Engineering and Management Systems
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    • v.13 no.4
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    • pp.398-407
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    • 2014
  • Shortages and delays in a humanitarian logistics system can contribute to the pain and suffering of survivors or other affected people. Humanitarian logistics budgets should be sufficient to prevent such shortages or delays. Unlike commercial supply chain systems, the budgets for relief supply chain systems should be able to satisfy demand. This study describes a comprehensive model in an effort to satisfy the total relief demand by minimizing logistics operations costs. We herein propose a strategic model which determines the locations of distribution centers and the total inventory to be stocked for each distribution center where a flood or other catastrophe may occur. The proposed model is formulated and solved as a mixed-integer programming problem that integrates facility location and inventory decisions by considering capacity constraints and time restrictions in order to minimize the total cost of relief operations. The proposed model is then applied to a real flood case involving 47 disaster areas and 13 distribution centers in Thailand. Finally, we discuss the sensitivity analysis of the model and the managerial implications of this research.

Implementation of the robust speed control system for DC servo motor using TDF compensator method (2자유도 보상법에 의한 직류서보전동기의 강인한 속도제어시스템 구현)

  • Kim, Dong-Wan
    • The Transactions of the Korean Institute of Electrical Engineers P
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    • v.52 no.2
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    • pp.74-80
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    • 2003
  • In this paper, a robust two-degree-of-freedom(TDF) the speed control system using $H_{\infty}$ optimization method and real genetic algorithm is proposed for the robust stability and the robust performance in dc servo motor system. This control system composed of feedback and feedforward controller. The feedback(FB) controller with $H_{\infty}$ optimization method is designed for real genetic algorithm that is model matching problem using mixed sensitivity function. The feedforward(FF) controller with $H_{\infty}$optimization method is minimized the error between transfer function of the optimal model and the overall transfer function. The proposed robust two-degree-of-freedom speed control system is simulated to the dc servo motor. By the simulation, feedback controller can obtain the robust stability property and feedforward controller can obtain the robust performance property under modelling error. The performance of the dc servo motor is analyzed by the experiment setting. The validity of the proposed method is verified through being compared with pid(proportional integrated differential)control system design method for the dc servo motor.

Damping of Low Frequency Oscillation in Power System using Robust Control of Superconductor Flywheel Energy Storage System (초전도 플라이휠 에너지 저장장치의 강인제어를 이용한 전력계통의 저주파진동 억제)

  • Lee, J.P.;Kim, H.G.
    • Progress in Superconductivity
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    • v.14 no.1
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    • pp.52-59
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    • 2012
  • In this paper, the robust superconductor flywheel energy storage system(SFESS) controller using $H_{\infty}$ control theory was designed to damp low frequency oscillation of power system. The main advantage of the $H_{\infty}$ controller is that uncertainties of power system can be included at the stage of controller design. Both disturbance attenuation and robust stability for the power system were treated simultaneously by using mixed sensitivity $H_{\infty}$ problem. The robust stability and the performance for uncertainties of power system were represented by frequency weighted transfer function. To verify control performance of proposed SFESS controller using $H_{\infty}$ control, the closed loop eigenvalue and the damping ratio in dominant oscillation mode of power system were analyzed and nonlinear simulation for one-machine infinite bus system was performed under disturbance for various operating conditions. The results showed that the proposed $H_{\infty}$ SFESS controller was more robust than conventional power system stabilizer (PSS).