• Title/Summary/Keyword: Mixed Compound

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Solubility of Nifedipine in Mixed Solvents and Antisolvent Crystallization (혼합용매에 대한 니페디핀의 용해도와 반용매 결정화)

  • Kang, Mi-Young;Yeo, Sang-Do
    • Korean Chemical Engineering Research
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    • v.58 no.1
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    • pp.92-97
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    • 2020
  • In this study, the solubilities of a pharmaceutical compound, nifedipine, in three mixed solvents were determined. In addition, the nifedipine, that was dissolved in solvents (acetone, DMF, methylene chloride), was recrystallized using antisolvents (water, hexane, carbon dioxide) The external shape, size, and melting point of the crystallized nifedipine were measured. As the mixed solvents, acetone+water, DMF+water, and methylene chloride+hexane were used, and the solubility of nifedipine decreased with increasing antisolvent concentrations in the mixtures. In case of acetone+water, the solubility maximum was observed due to the density anomaly of the mixture, and this phenomenon was not observed in other systems. The crystallized nifedipine particles exhibited the bladed, equant, and prismatic habits, and the particles size was significantly reduced compared to the raw material. The average particle size of raw nifedipine was 337 ㎛, and the size of crystallized particles was in the range of 11.6~69.8 ㎛. All the crystallized nifedipine particles had the same thermal behavior and this result was not influenced by the change of solvent and antisolvent.

A Study on Efficiency of Mixed Model (BTO+BTL) for Public-Private Partnership Projects (민간투자사업 혼합방식(BTO+BTL)의 효율성에 관한 연구)

  • Kim, Do-Il;Jin, Run-Zhi;Hyun, Chang-Taek
    • Korean Journal of Construction Engineering and Management
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    • v.13 no.5
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    • pp.53-63
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    • 2012
  • Korean Public-Private Partnership, mainly implemented using BTO (Build-Transfer-Operate) and BTL (Build-Transfer-Lease) methods, has contributed in increasing benefits of the people by providing the needed public services in a timely and efficient manner. It has also induced flexible national fiscal management. However, in addition to the repeal of the Minimum Revenue Guarantee (MRG) program in 2009, changes in business environment including recent financial crisis aggravated financial situation in pursing PPPs, resulting in significant contraction of BTO projects. Therefore, the new methods are to be suggested and applied to overcome this situation. This paper seeks to find ways to apply "Mixed Model," characterized as the compound of BTO and BTL, two different implementation methods of PPPs, as an enhanced burden-sharing mechanism.

Characteristics of Concrete Using Ready-Mixed Concrete Recycled Water Mixed with Industrial By-Product Desulfurization Gypsum (산업부산물 탈황석고 혼입 레디믹스트콘크리트 회수수를 이용한 콘크리트의 특성)

  • Kim, Young-Yeop;Lee, Han-Seung
    • Journal of the Korean Recycled Construction Resources Institute
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    • v.8 no.4
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    • pp.395-403
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    • 2020
  • CaO-based by-product, which consist of CaO, SO3, Al2O3 and so on, has being used to raw materials of CaO compound. When It was applied to recycling water of remicon, concrete performance can be enhanced because hydration reaction of powder material is accelerated. In this study, activated-sludge, which was putted desulfurization gypsum of CaO-based in recycling water, was manufactured to verify effect of them, and then they was investigated by characteristics of redy-mixde concrete. As a result of concrete tests, it was confirmed that there is no problem of strength or drying shrinkage while ensuring workability. Therefore, the possibility of specific application using activated sludge was confirmed.

Studies on Application of Organic-Compound Fertilizer on Hilly Mixed Sward Ⅰ. Effect of organic-compound fertilizer application on dry matter yield and botanical composition of grass-clover mixtures (山地草地에 對한 有機質 複合肥料의 施用에 關한 硏究 Ⅰ. 有機質 複合肥料의 施用이 混燔牧草의 乾物收量과 植生變化에 미치는 影響)

  • Park, Geun-Je;Lee, Hyuk-Ho;Shin, Jae-Soon;Lee, Jong-Yeol
    • Journal of The Korean Society of Grassland and Forage Science
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    • v.8 no.2
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    • pp.92-98
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    • 1988
  • With a purpose of finding out the effects of magnesium and boron enriched organic-compound fertilizer application on the dry matter yield, yield components and changes in the botanical composition on the hilly pasture, a field experiment was arranged with five different treatments as a randomized block desigh and lasted from September, 1984 to the end of growing season in 1986. The results obtained are summarized as follows: 1. As a early plant growth and development, winter hardiness, growth vigour and coverate of grasses at the plots with organic-compound fertilizer application were better comparing to single dressing. 2. Average dry matter yields for two years were shown significantly high due to increasing amount of fertilizer. This trend was same both single and organic-compound fertilizer. And dry matter yields with organic-compound fertilizer application of low (8,693.1 kg/ha) and conventional level (12,758.7 kg/ha) were appeared to increase by 10 and 15% than those of single dressing of Low (7,930.6 kg/ha) and conventional level (11,122.6 kg/ha), respectively. But it was not significant difference. 3. Dry matter yield of grasses was significantly gained by increasing amount of fertilizer. The yield of legumes at the plots with organic-compound fertilizer application the yields of grasses were a litle more increased by 8-14%, and legumes were much more gained by 26-29% than those of the same species groups with single dressing, but it was not significant between the differnet kinds of fertilizer in the same fertilizing level. 4. At the grassland management, the rate of legumes tended to dominate at the plot without fertilization gradually. On the other hand, the botanical compositions and the rates of grasses were much better maintained at the plots with fertilization. But the rates of legumes with organic-compound fertilizer application tended to increase a little more than those of single dressing gradually. 5. All of the soil chemical properties after the experiment were much more improved comparing to before the experiment. But the average contents of soil organic matter and available $P_2O_5$ were slightly higher at the plot with organic-compound fertilization, on the other hand, pH and exchangeable cations tended to a little less than those of single dressing.

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Three Dimensionally Ordered Microstructure of Polycrystalline Zirconia Ceramics with Micro-Porosity

  • Chang, Myung Chul
    • Journal of the Korean Ceramic Society
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    • v.53 no.1
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    • pp.50-55
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    • 2016
  • In order to make a highly ordered three-dimensionally macro-porous structure of zirconia ceramics, porogen precursors PMMA beads were prepared by emulsion polymerization using acrylic monomer. The monodisperse PMMA latex beads were closely packed by centrifugation as a porogen template for the infiltration of zirconium acetate solution. The mixed compound of PMMA and zirconium acetate was dried. According to the firing schedule, dry compacts of PMMA and zirconium acetate were calcined at $475^{\circ}C$ to obtain micro-, macro-, and meso- structures of polycrystalline zirconia with monodispersed porosity. Inorganic frameworks composed of $ZrO_2$ were formed and showed a three Dimensionally Ordered Microstructure [3DOM] of $ZrO_2$ ceramics. The obtained $ZrO_2$ skeleton was calcined at $710^{\circ}C$. The 3DOM $ZrO_2$ skeleton showed color tuning in solutions such as deionized [DI] $H_2O$ and/or methanol. The monodispersed crystalline micro-structure with micro/meso porosity was observed by FE-SEM.

A Study on Plastic Injection Molding of a Metallic Resin Pigment using a Rapid Heating and Cooling System (급속가열냉각장치에 의한 금속성 안료 사출성형)

  • Lee, Gyu-Sang;Jin, Dong-Hyun;Kwak, Jae-Seob
    • Journal of the Korean Society of Manufacturing Process Engineers
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    • v.14 no.2
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    • pp.87-92
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    • 2015
  • The injection molding process is widely used in the production of most plastic products. In order to make metal-colored plastic products like those found in modern luxury home alliances, metallic pigments are mixed with a basic resin material for injection molding. However, process control for metal-colored plastic products is extremely difficult due to the non-uniform melt flow of the metallic resin pigments. In this study, the effect of process parameters on the quality of a metal-colored plastic product is evaluated. A rapid mold cooling method using a compressed cryogenic fluid is also proposed to decrease the content of undesired compounds within the plastic product.

$Ag(Ta_{0.5}Nb_{0.5})O_3$ ceramic의 전기적, 유전적 특성 연구

  • Lee, Gyeong-Su;Lee, Gyu-Tak;Ham, Yong-Su;Go, Jong-Hyeok
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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    • 2009.11a
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    • pp.89-89
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    • 2009
  • In this study, the structural characteristics and the electrical properties of $Ag(Ta,Nb)O_3$ ceramics were investigated. Compound ceramics were fabricated by the mixed oxide method. The sintering temperature was 1200 $^{\circ}C$. The dielectric properties of $Ag(Ta,Nb)O_3$ ceramics were measured from 1 kHZ to 1 MHz. The electrical properties of $Ag(Ta,Nb)O_3$ ceramics were investigated at the various temperature ranges.

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Mechanical Properties Evaluation of Composites for Electromagnetic Waves Absorption (전자기파 흡수용 복합재료의 기계적 강도평가)

  • 오정훈;김천곤;홍창선
    • Proceedings of the Korean Society For Composite Materials Conference
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    • 2002.05a
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    • pp.105-108
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    • 2002
  • Materials, matrices mixed with various kinds of conductive or magnetic powder, such as ferrite, have been used as the electromagnetic wave absorbing ones, so called RAM(radar absorbing material). The structure that does not only have electromagnetic waves absorbing property like RAM but also supports loads is called RAS(radar absorbing structure). One of the existing manufacturing process of RAS is to compound with conductive powders the glass fiber-reinforced composite with good permeability and the ability to support loads. The process, however, causes a number of problems, such as the degradation in the mechanical properties of the composite, especially, interlamina shear strength. In this study, mechanical properties of glass fabric/epoxy composite containing 7wt% carbon black powders were measured and compared with pure glass fabric/epoxy composites.

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The Effect of Lignin Compound on Dispersibility of Concrete (Lignin 화합물의 Concrete 분산성에 대한 연구)

  • 문정연;한기성
    • Journal of the Korean Ceramic Society
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    • v.13 no.3
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    • pp.37-42
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    • 1976
  • Although the water mixed into the concrete plays the role of hydration and acquiring the necessary workability, the more portion of water acts to obtain the substantial workability rather than to complete the hydration. However, the excess amount of water causes the poor quality of concrete, therefore it is useful to add the minimum amount of water as required as to acquire the proper workability. There have been the considerable numbers of investigations in which the dispersion phenomena of strong eletrolytic high polymer compounds such as lignosulfate and some of surface activation agents were studied to utilize as the dispersion agent of concrete. In the present study, Na-lignate, dispersion properties of which has not been studied yet, were investigated with the purpose of utilizing as a dispersion agent of concrete. The microscopic observations showed a great improvement in the dispersion of cement particles, also the fluidity and compressive strength of concrete were remarkably increased with the addition of Na-lignate: The addition of Na-lignate by 0.02% showed the increase of 1.76 times and 1.27 times of slump value and flow value respectively, and the compressive strength was increased by 1.07 times.

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Hydrophobic Interaction Between the Acyl Moiety of Choline Esters and the Active Site of Acetylcholinesterase

  • Myung, Pyung-Keun;Sok, Dai-Eun
    • BMB Reports
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    • v.28 no.4
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    • pp.290-292
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    • 1995
  • Existence of a binding site for choline esters with an acyl chain of various sizes was examined by comparing the inhibitory potency of the respective compound. In contrast to acetylcholine, which showed a pure competitive pattern of inhibition, choline esters with an acyl chain of a long size ($C{\geq}5$) expressed a mixed type of inhibition. Binding of choline esters containing a long chain ($C_7-C_{12}$) to the hydrophobic region in the active site is deduced from a linear relationship between the $K_{iE}$ value and the size of acyl moiety, and a good hydrophobicity relationship. In addition, the non-competitive component in the inhibition of acetylcholinesterase seems to be due to the interaction of choline esters with both the hydrophobic site and the trimethylammonium-binding site in the active center of the acetylated acetylcholinesterase.

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