• 대한수의학회지
• /
• 제33권2호
• /
• pp.189-198
• /
• 1993

The present study was undertaken to provide basic data on endochondral ossification for the axis in developing Miniature Schnauzers. This study was determined to the morphological features and development of growth plast in the axis of this experimental animals by histological and histochemical methods. The axis from 2 healthy Miniature Schnauzers(postnatal 6hr, 5week) was used. The obtained results were as follows : 1. In 5-week-old Miniature Schnauzer, the axis consisted of 4 separate ossification centers : centrum l, intercentrum 2, centrum 2 and epiphysis. Intercentrum 2 was intercalated between centrum 1 cranially, centrum 2 caudally. 2. The space of centrum 1 was more broader than the other ossification centers. 3. The zone of reserved chondrocytes was more extensive than the zone of proliferative chondrocytes, trabeculation was weakly observed, however, the proximal epiphyseal plate of axis was actively trabeculation observed in the zone of calcified chondrocytes. 4. Eighteen columns of chondrocytes were observed in the centrum 1 and five to seven columns of chondrocytes were observed in the centrum 2 of Miniature Schnauzer(postnatal 5 week) 5. A positive reaction to alcianophility was observed in all the territorial matrix at the zone of hypertrophic chondrocytes in this experimental animals.

• International Journal of Fluid Machinery and Systems
• /
• 제4권1호
• /
• pp.191-198
• /
• 2011

Based on the consideration that the cavitation would affect the operation stability of miniature pumps, the 3-D turbulent cavitating flow in a test pump was simulated by using a mixed cavitation model and k-${\omega}$ SST turbulence model. In order to investigate the influence of inlet geometry parameters on the cavitation performance of the miniature pump, two more impellers are designed for comparison. Based on the results, the following conclusions are drawn: 1) Cavitation performance of the double suction shaft-less miniature pump having different impeller is equivalent to the centrifugal pump having ordinary size, though the flow passage at impeller inlet is small; 2) The miniature pump having radial impeller can produce much higher pump head, but lower cavitation performance than that having the impeller based on the conventional design method; 3) It is believed that by applying the double suction design, the miniature pump achieved relatively uniform flow pattern upstream the impeller inlet, which is favorable for improving cavitation performance.

• Reproductive and Developmental Biology
• /
• 제35권3호
• /
• pp.385-390
• /
• 2011

The purpose of this study was undertaken to evaluate of cryopreservation efficiency in ${\alpha}$ 1,3-galactosyltransferase knock-out(GalT KO) cloned miniature pig sperm. To compare ability of frozen-thawed sperm characteristics, three different pig strains (GalT KO) cloned miniature pig, PWG miniature pig and Duroc were used. The ejaculated semen from the three pig species was diluted with same volume extender and added to LEY solution for freezing. The diluted semen was placed in 0.5 ml straws, and freezing was initiated by exposing the straws to liquid nitrogen ($LN_2$) vapours for 10 min before placing them into $LN_2$ for cryopreservation. After thawing, the sperm ability were assessed for viability (SYBR-14/PI staining), abnormality (Rose Bengal staining), and acrosome status (intactness, intensity and capacitation) (chlorotetracycline, CTC staining). The viability of frozen-thawed GalT KO pig sperm had no significant difference as compared with Duroc and PWG miniature pig sperm. However, The CTC pattern of frozen-thawed GalT KO cloned miniature pig spermatozoa showed significantly lower rates in F pattern and AR pattern (p<0.05) and significantly higher rates in B pattern than Duroc and PWG miniature pig (p<0.05). The abnormality of GalT KO cloned miniature pig sperm was significantly lower as compared to Duroc and PWG miniature pig sperm (p<0.05). In conclusion, GalT KO cloned miniature pig semen can be cryopreserved successfully and used for artificial insemination reasonably.

• 한국임상수의학회지
• /
• 제24권4호
• /
• pp.593-596
• /
• 2007

The purpose of this study is to investigate normal hepatobiliary functions in healthy miniature pigs. $^{99m}Tc-DISIDA$ hepatobiliary scintigraphy(HBS) was used for it. Five mCi dose of $^{99m}Tc-DISIDA$ was injected intravenously into 3 healthy adult miniature pigs, and dynamic images were obtained during 1 hour. $^{99m}Tc-DISIDA$ HBS in a miniature pig was evaluated for 6 variables. A cardiac washout occurred within 1 min in all miniature pigs and radioactivities in the gallbladder were not detected in two miniature pigs. Thus, the initial radioactivity and Tmax of the gallbladder were non-available to identify. Mean Tmax of liver was $8.67{\pm}2.08$ min and initial small intestinal radioactivity was seen at $9.67{\pm}2.52$ min after $^{99m}Tc-DISIDA$ injection. Mean hepatic washout time was not detected in 60 min dynamic images. Therefore, $^{99m}Tc-DISIDA$ HBS is the effective diagnostic method to evaluate the function of hepatocyte and bile flow rate. However, it was not a proper method to evaluate the function of gallbladder, which indicates that an additional study is needed to further specify the reasons for the absence of radioactivities in gallbladder of two miniature pigs.

• 제어로봇시스템학회:학술대회논문집
• /
• 제어로봇시스템학회 1996년도 Proceedings of the Korea Automatic Control Conference, 11th (KACC); Pohang, Korea; 24-26 Oct. 1996
• /
• pp.24.2-27
• /
• 1996

This paper is a study on the fuzzy force control of a miniature gripper driven by piezoelectric bimorph actuator. The system is composed of two flexible cantilevers, a stepping motor, a laser displacement transducer and two semiconductor force sensors attached to the beams. Obtained results show that the present artificial finger system works well as a miniature gripper, which produces approximately 0.06N force in the maximum. Further, the fuzzy position/force control algorithm is applied to the soft-handing gripper for stable grasping of a object. It revealed that the fuzzy rule-based controller be efficient controller for the stable drive of the flexible miniature gripper. It also showed that two semiconductor strain gauges located in the flexible beam play an important roles for force control, position control and vibration suppression control.

• 대한전기학회:학술대회논문집
• /
• 대한전기학회 2006년도 제37회 하계학술대회 논문집 B
• /
• pp.627-628
• /
• 2006

Miniature BLDC is widely used in industrial applications because of high driving efficiency and high torque characteristic. Otherwise the general BLDC, torque ripple of a high speed miniature BLDC is serous during conduction due to the very low electrical time constant. This paper present instant voltage and current control for torque ripple reduction of a high speed miniature BLDC. Computer simulation and experiment test for 40,000 rpm miniature BLDC show the verification of the proposed control method.

• 한국수정란이식학회지
• /
• 제29권2호
• /
• pp.119-125
• /
• 2014

Although the majority of surviving pigs cloned by somatic cell nuclear transfer (SCNT) appear to be physiologically normal, there is a general lack of detailed hemato-physiologic studies for the period of early adulthood to substantiate this claim. In the present study, we investigated variation in blood chemistry and endocrinological parameters between mesenchymal stem cells (MSCs) derived from cloned and normal age-matched female and male miniature pigs. Cloned females and males showed normal ranges for complete blood count assessments. Biochemical assessments showed that ${\gamma}$-GGT, ALT and cholesterol levels of male and female clones were significantly (P<0.05 or P<0.01, respectively) higher than that of age-matched control miniature pigs. Variations in insulin and IGF-1 were higher in female clones than in male clones and controls. Thus, although female and male cloned miniature pigs may be physiologically similar to normal animals, or at least within normal ranges, a greater degree of physiological and endocrinological variation was found in cloned pigs. The above variation must be taken into account before considering cloned female or male miniature pigs for various biomedical applications.

• Nuclear Engineering and Technology
• /
• 제48권3호
• /
• pp.799-804
• /
• 2016

A miniature X-ray tube based on a carbon-nanotube electron emitter has been employed for the application to a dental radiography. The miniature X-ray tube has an outer diameter of 7 mm and a length of 47 mm. The miniature X-ray tube is operated in a negative high-voltage mode in which the X-ray target is electrically grounded. In addition, X-rays are generated only to the teeth directions using a collimator while X-rays generated to other directions are shielded. Hence, the X-ray tube can be safely inserted into a human mouth. Using the intra-oral X-ray tube, a dental radiography is demonstrated where the positions of an X-ray source and a sensor are reversed compared with a conventional dental radiography system. X-ray images of five neighboring teeth are obtained and, furthermore, both left and right molar images are achieved by a single X-ray shot of the miniature X-ray tube.

• Reproductive and Developmental Biology
• /
• 제33권4호
• /
• pp.249-255
• /
• 2009

The miniature pig is considered to be a better organ donor breed for xenotransplantation than other pig breeds because the size of the organs of the miniature pig is similar to that of humans. In this study, we aimed at identifying differentially expressed genes in the miniature pig ovary during pregnancy. For this, we used the miniature pig ovary model, annealing control primer-based reverse transcription polymerase chain reaction (PCR), quantitative real-time PCR (qRT-PCR), and northern blotting analysis. We identified 13 genes showing differential expression on the based of pregnancy status and validated 8 genes using qRT-PCR. We also sequenced the full-length cDNA of ephrin receptor A4 (EphA4), which had a significant difference in expression level, and validated it by northern blotting. These genes may provide a better understanding of the cellular and molecular mechanisms during pregnancy in miniature pig ovary.

• 한국항공우주학회지
• /
• 제43권3호
• /
• pp.272-281
• /
• 2015

초소형 스마트탄은 탄도를 수정하여 손쉽게 목표물을 타격할 수 있도록 고안된 개인 휴대용 유도미사일이다. 초소형 스마트탄은 유도미사일에 준하는 기능을 수행하는데 반하여 그 크기가 일반 병사들이 쉽게 휴대할 수 있도록 축소됨으로써 아군의 전력과 생존율을 크게 높일 수 있을 것으로 기대된다. 본 논문에서는 초소형 스마트탄의 탄도수정을 위해 사용된 구동장치를 중심으로 해외에서 선행된 기술개발 사례와 특허들을 수집해 보았다. 이를 바탕으로 초소형 스마트탄의 개발을 위한 소요기술들을 분석해 보고, 추후 개념설계를 위한 초석을 마련하였다.