• Proceedings of the Korean Society of Computer Information Conference
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• 2021.01a
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• pp.265-267
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• 2021

본 논문에서는 코로나바이러스(COVID-19)와 같은 응급상황에서 필요한 환자의 이동 및 검사 경로 등을 MCMF(Min-cost Max-flow, 최소-비용 최대-유량) 알고리즘 기반의 에이전트 이동을 활용하여 효율적으로 푸는 방법에 대해 살펴본다. 환자의 수가 유동적으로 변화하기 때문에 고정된 경로가 아닌 매번 최적화시킬 수 있는 경로는 요즘 같은 COVID-19 시대에 필요한 기술이며, 이와 같은 응급상황에서는 이른 시일 내에 대처하고 조치하는 것이 피해를 최소화할 수 있다. 이러한 상황에서는 응급상황에 대처하기 위한 정보들을 어떻게 사용하는지에 따라 상황에 대한 처리 시간이 달라질 수 있다. 본 논문에서는 응급상황에 대한 처리 시간을 최소한으로 하기 위해 MCMF 알고리즘을 적용하고 지도 API와 실제 병원 위치 등을 이용하여 실제로 시간을 단축할 수 있는지 연구하고 분석한다.

• The Korean Journal of Nuclear Medicine Technology
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• v.14 no.1
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• pp.3-7
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• 2010

Purpose: The usefulness of Positron Emission Tomography (PET) images in diagnosis, staging, recurrent and treatment response evaluation has already been known. However, tumors which are small size, located in lower lobe of lung or upper lobe of liver are shown misalignment, distortion and different Standard Uptake Value (SUV) by respiration in PET images. Therefore, if radiotherapy based on normal respiration, it may cause low treatment response or more side effects because targets which had to treat, out of treat range or over dose to normal tissue. The purpose of this study is to evaluate attenuation-correction with Average CT (ACT) for more accuracy SUV measurement and minimize artifact by respiration. Materials and Methods: 13 patients, who had tumors which are around the diaphragm, underwent ACT scan after Helical CT (HCT) scan with PET/CT (Discovery DSTE 8; GE Healthcare). We quantified the differences between attenuation corrected image with HCT and attenuation corrected image with ACT in artifact size and maximum SUV ($SUV_{max}$). Artifacts were evaluated by measurement of the curved photogenic area in the lower thorax of the PET images for all patients. $SUV_{max}$ was measured separately at the primary tumors. Analysis program was Advantage Workstation v4.3 (GE Healthcare). Patients were injected with 7.4 MBq (0.2 $mC_i$) per kg of $^{18}F$-FDG and scanned 1 hour after injection. The PET acquisition was 3 minute per bed. Results: Significantly lower artifact were observed in PET/ACT images than in PET/HCT images (below-thoracic artifacts caused by under corrected $1.5{\pm}3.5$ cm vs. $13.4{\pm}4.2$ cm). Significantly higher $SUV_{max}$ were noted in PET/ACT images than in PET/HCT images in the primary tumor. Compared with PET/HCT images, $SUV_{max}$ in PET/ACT images were higher by $5.3{\pm}3.9%$ (mean value) tumor. The highest difference was observed in Lower lobe of lung (7.7 to 8.7; 13%). Conclusion: Due to its significantly reduced artifacts in lower thoracic, attenuation corrected image with ACT images provided more reliable $SUV_{max}$ and may be helpful in monitoring treatment response. Moreover, ACT can separate upper lobe of liver and lower lobe of lung, it may be helpful in interpretation. ACT will be clinically useful, considering increased dose caused by ACT scan and adapt.

• Journal of Radiation Protection and Research
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• v.44 no.1
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• pp.26-31
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• 2019

Background: Stereotactic ablative radiotherapy (SABR) plans in prostate cancer are compared and analyzed to investigate the low magnetic effect (0.35 T) on the dose distribution, with various dosimetric parameters according to low magnetic field. Materials and Methods: Twenty patients who received a 36.25 Gy in five fractions using the MR-IGRT system (ViewRay) were studied. For planning target volume (PTV), the point mean dose ($D_{mean}$), maximum dose ($D_{max}$), minimum dose ($D_{min}$) and volumes receiving 100% ($V_{100%}$), 95% ($V_{95%}$), and 90% ($V_{90%}$) of the total dose. For organs-at-risk (OARs), the differences compared using $D_{max}$, $V_{50%}$, $V_{80%}$, $V_{90%}$, and $V_{100%}$ of the rectum; $D_{max}$, $V_{50%}$, $V_{30Gy}$, $V_{100%}$ of the bladder; and $V_{30Gy}$ of both left and right femoral heads. For both the outer and inner shells near the skin, $D_{mean}$, $D_{min}$, and $D_{max}$ were compared. Results and Discussion: In PTV analysis, the maximum difference in volumes ($V_{100%}$, $V_{95%}$, and $V_{90%}$) according to low magnetic field was $0.54{\pm}0.63%$ in $V_{100%}$. For OAR, there was no significant difference of dose distribution on account of the low magnetic field. In results of the shells, although there were no noticeable differences in dose distribution, the average difference of dose distribution for the outer shell was $1.28{\pm}1.08Gy$ for $D_{max}$. Conclusion: In the PTV and OARs for prostate cancer, there are no statistically-significant differences between the plan calculated with and without a magnetic field. However, we confirm that the dose distribution significantly increases near the body shell when a magnetic field is applied.

• Korean Journal of Exercise Nutrition
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• v.16 no.2
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• pp.101-111
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• 2012

The purpose of this thesis is to investigate whether taurine supplementation in combination with fructose improves both energy metabolism and exercise capacity. Eight collegiate female subjects were recruited for the study. Each subject went through threecross-over designs: control(fluid), fructose, and taurine plus fructose supplementation trials. Subjects received taurine supplementation 100 mg/kg a day for two weeks. After the supplementation, all subjects take 10% fructose at 15 min prior to exercise, immediately before exercise, and every 15 min during exercise. Subjects received 150 ml fluid as placebo during the same procedure. The subjects performed submaximal exercise at the exercise intensity of 60% for 45 min and then 80% of maximal oxygen uptake (VO_2max) until exhaustion time. A 10ml blood sample was taken for measuring the level of glucose, ammonia, lactate, free fatty acids, and insulin every 15 min during exercise at 60% of VO_2max. The blood glucose levels was significantly higher at 45 min and 50 min exercise after supplementation of fructose, and immediately before exercise and 50 min exercise after taurine plus fructose compared to the placebo trial. However, the values tended to be lower in taurine plus fructose supplementation compared to the fructose trial. The levels of both lactate and ammonia were significantly lower compared to the placebo, while the exhaustion time was significantly increased. The level of free-fatty acids was significantly lower at 30, 45, and 50 min after fructoseand fructose plus taurine supplementation compared to the placebo trial. The level of glucagon was significantly lower at 15, 30, 45, and 50 min after fructose and fructose plus taurine supplementation compared to the placebo trial. There was no differences in insulin concentration among three treatments. This thesis concludes that combined taurine and fructose supplementation prior to exercise may improve exercise tolerance time and energy metabolism, lowering the muscle fatigue factors such as lactate and ammonia.

• Journal of Life Science
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• v.25 no.7
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• pp.819-825
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• 2015

The use of fructose-containing sports beverage drinks has increased in recent years, especially at sport events, because of their reported ergogenic effects. However, the ingestion of low to moderate doses of caffeinated energy drinks has been associated with adverse side effects such as insomnia or increased nervousness. The purpose of this study was to investigate the effects of fructose beverage supplementation on cardiopulmonary function, blood lactate levels, and inflammatory reactions. We recruited 8 young adult subjects from D university and measured their cardiopulmonary functions before and after supplementation with sports beverage drinks. We also measured blood lactate and inflammatory reactions after a 20 min recovery period. Exercise time, maximal oxygen uptake (V0₂max), and AT HRmax were significantly increased (p<0.05) in the period of before and after sports beverage supplementation. However, no significant differences were observed in RPE, AT RER, V0₂max RER, AT V0₂max, and maximum heart rate (HRmax). Lactate levels also significantly decreased after 20 min recovery with sports beverage supplementation. Sports beverage supplementation therefore may enhance maximal V0₂max and increase the exercise duration time. These drinks may also be helpful in promoting rapid recovery of fatigue variables and increasing exercise performance time.

• Archives of Pharmacal Research
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• v.21 no.6
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• pp.677-682
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• 1998

The present study was designed to examine the metabolism of 1-anilino-8-naphthalene sulfonate (ANS), an anionic compound which is transported into liver via "multispecific organ ic anion transporter", with rat hepatic microsomes. TLC analysis indicated that the fluorescent metabolites were not produced to a measurable extent, which made it possible to assess the ANS metabolism by measuring the fluorescence disappearance. The metabolism of ANS was remarkably inhibited by the presence of SKF-525A as well as by the substitution of 02 by CO gas. ANS metabolism by microsomes also required NADPH as a cofactor. These results indicated that the microsomal monooxygenase system might be mainly responsible for the ANS metabolism. The maximum velocity ($V_{max}$) and Michaelis constant ($K_m$) were calculated to be $4.3{\pm}0.2$ nmol/min/mg protein and $42.1{\pm}2.0\;{\mu}M$, respectively. Assuming that 1g of liver contains 32mg of microsomal protein, the $V_{max}$ value was extrapolated to that per g of liver ($V_{max}^I$). The intrinsic metabolic clearance ($CL_{int}$) under linear conditions calculated from this in vitro metabolic study was 3.3ml/min/g liver, being comparable with that (3.0ml/min/g liver) calculated by analyzing the in vivo plasma disappearance curve in a previous study. Furthermore, the effects of other organic anions on the metabolism of ANS were examined. Bromophenolblue (BPB) and rose bengal (RB) competitively inhibited the metabolism of ANS, while BSP inhibited it only slightly. The inhibition constant ($K_i$) of BPB ($6\;{\mu}M$) was much smaller than that of RB ($200\;{\mu}M$). In conclusion, the microsomal monooxygenase system plays a major role in the metabolism of ANS, and other unmetabolizable organic anions (BPB and RB) compete for this metabolism.

• Journal of Biosystems Engineering
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• v.23 no.5
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• pp.445-456
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• 1998

This study was carried out to evaluate the performance of a medium scale rice polisher of 2.5 t/h and to improve its performance for producing the clean rice with high quality. The maximum internal pressure, broken rice ratio. whiteness in the rice polisher were investigated, and the effects of outlet resistance, water spraying rate, shaft revolution speed and rice moisture content on the polishing performance were analyzed to find out proper operating conditions. The conclusions of this study were as follows: 1. In the performance evaluation of the polisher, the broken rice ratio increment of 0.1%, the max. internal pressure of about 11 N/${cm}^2$, and whiteness increment of 2.2~3.7 resulted at the conditions of 20 PS driving power, 950 rpm, 150 cc/min water spraying rate, 44.1 Nㆍcm outlet resistance and about 15% rice moisture content. 2. Though max. internal pressure and whiteness at the 17% rice moisture content were higher than those at the 15% moisture content under the same operating conditions of the polisher, but the broken rice rate at the 17% moisture content was absolutely low compared with that at 15% moisture content. The water spraying effect to reduce broken rice and to increase whiteness was much significant at the 15% moisture content not significant at 17% moisture content. 3. The main parameter of the performance was outlet resistance, and low resistance of about 44.1 Nㆍcm was recommended at the polisher. 4. The proper water spraying rate in the polisher was about 150 cc/min. 5. As the shaft revolution speed decreased from 950 rpm and 800 rpm to 650 rpm, the broken rice ratio increased and whiteness decreased. 6. As the driving power of the polisher increased from 20 PS to 30 PS, the max. internal pressure decreased by about 1~2.5 N/${cm}^2$ and whiteness increased by about 1~2, but the broken rice rate was not changed. 7. The proper operating conditions of the polisher seemed to be the revolution speed of 800-950 rpm, the water spraying rate of about 150 cc/min, the oulet resistance of about 44.1 N.cm and 30 PS driving power.

• Asian-Australasian Journal of Animal Sciences
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• v.24 no.10
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• pp.1372-1376
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• 2011

The content of Ca in milk exceeds the typical saturation level of Ca salts, which is necessary for neonate growth. This calcium is distributed between the casein micelles in the colloidal and aqueous phases. Information on the properties of calcium activity in the aqueous phase is limited compared with that on the properties of bound or sequestrated calcium. The objectives of this study were to evaluate the changes in calcium activity in fresh milk using an ion-selective electrode and to assess the relationship between calcium activity and milk production in hot season. Milk samples collected from 10 cows at the National Agricultural Research Center for Kyushu Okinawa Region in June to October (Min-Max: 7.2-$35.2^{\circ}C$, 24.3-100% RH) were analyzed on total calcium concentrations and calcium activity. We observed that the rectal temperature of the cows increased according to elevation of ambient temperature but that the pH of the collected milk ($6.61{\pm}0.01$ (Mean${\pm}$SEM)) was not significantly influenced by rectal and ambient temperature. Total calcium concentrations and calcium activity in fresh milk decreased in July (Min-Max: 21.1-$33.5^{\circ}C$, 48.9-100.0% RH) compared with the values after August (Min-Max: 18.1-$35.0^{\circ}C$, 26.5-96.2% RH) (p<0.05); however, there was no significant correlation between the two parameters. The ratio of calcium activity to total calcium concentration decreased after August compared with the values in June and July (p<0.05). The calcium activity in fresh milk was positively correlated with milk yield (r = 0.45, p<0.01) and negatively correlated with milk lactose content (r = -0.53, p<0.01). These results suggest that the calcium activity in milk could be affected by ambient temperature and might be associated with milking production in hot season.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.16 no.8
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• pp.1593-1598
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• 2012

In this paper, we propose an intelligent signal control method based on fuzzy logic applicable in real time. We design membership functions to model occupied time and the number of vehicles for each lane. A priority for each signal phase is computed by the popular Max-Min fuzzy inference based on control rules and membership degrees of prepared two functions at any given time. A tie breaking scheme is considering weighted sum of the rate of occupied time per number of vehicles in that block and the standard deviation of these blocks. Only a signal phase with the highest priority is opened and all others are closed and the duration of the phase opening is computed proportional to the rate of number of weighting vehicles in that signal per all weighted vehicles. The simulation result shows that the proposed method is more efficient than the static control in all simulation conditions in $2{\times}3$ experimental designs with the number of vehicles in intersection and congestion degrees that have all three levels.

• International journal of advanced smart convergence
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• v.5 no.3
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• pp.56-60
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• 2016

Body physical technique is to pursuit the dynamic motion by the physical index(PI) and sensory index(SI) on the physical body function. Function of the physical body by the motor condition is organized the dynamic physical system. For the physical motion of signal, we is defined a runout value of the body function by the physical index on the dynamic state. The concept of body physical index was identified the reference of physical index and sensory index by the body technique. As to detect a variation of the body physical technique-runout physical index(BPT-RPI) of the maximum and average and minimum in terms of physical motion, and the dynamic sensory value that was a runout function of the vision variation of the $Vi-{\xi}_{MAX-AVG-MIN}$ with $2.53{\pm}4.85$ units, that was a runout function of the vestibular variation of the $Ve-{\xi}_{MAX-AVG-MIN}$ with ($-0.69{\pm}2.32$)units, that was a runout function of the somatosensory variation of the $So-{\xi}_{MAX-AVG-MIN}$ with ($-1.43{\pm}-1.36$) units. The dynamic physical motion will be to confirm at the variable function of the runout motion for the body function values of dynamic physical index on the BPT-RPI that was identified an evaluation of the physical sensory function by the dynamic physical system. Runout body system was mentioned of a physical body situation by the mild moving and was refer a runout data of dynamic physical nervous index.