• 보존과학연구
• /
• 통권30호
• /
• pp.103-124
• /
• 2009

Major and trace elements and cross section textures of the large-sized jar-coffins excavated in the Young San river area have been analyzed for categorization according to geochemical characteristics of the raw materials. As results, we have found out that the jar-coffins of the Oryang-dong and Ungok-dong have very similar characteristics, and those of Songwol-dong and Jangdeung show distinguishable characteristics from the others. In addition, similar characteristics have been detected in some U-shape jar-coffins from several sites such as Oryang-dong, Ungok-dong, Sinchon-ri, Mansu-ri and Yeon-ri posess on trace elements and cross section texture. These results indicate that there was active physical migration although the detail route of the physical migration is unclear at current stage.

• Journal of Korean Neurosurgical Society
• /
• 제59권1호
• /
• pp.17-25
• /
• 2016

Objective : Treatment of intracranial dural arteriovenous fistulas (dAVFs) remains a challenge. However, after introduction of Onyx, transarterial approach is the preferred treatment option in many centers. We report our experience of dAVFs embolization with special emphasis on transarterial approach. Methods : Seventeen embolization procedures were performed in 13 patients with dAVFs between Jan 2009 and Oct 2014. Clinical symptoms, location and type of fistulas, embolization methods, complications, radiological and clinical outcomes were evaluated using charts and PACS images. Results : All 13 patients had symptomatic lesions. The locations of fistulas were transverse-sigmoid sinus in 6, middle fossa dura in 4, cavernous sinus in 2, and superior sagittal sinus in 1 patient. Cognard types were as follows : I in 4, IIa in 2, IIa+IIb in 5, and IV in 2. Embolization procedures were performed ${\geq}2$ times in 3 patients. Nine patients were treated with transarterial Onyx embolization alone. One of these required direct surgical puncture of middle meningeal artery. Complete obliteration of fistulas was achieved in 11/13 (85%) patients. There were no complications except for 1 case of Onyx migration in cavernous dAVF. Modified Rankin scale score at post-operative 3 months were 0 in 11, and 3 in 2 patients. Conclusion : Transarterial Onyx embolization can be a first line therapeutic option in patients with dAVFs. However, transvenous approach should be tried first in cavernous sinus dAVF because of the risk of intracranial migration of liquid embolic materials. Furthermore, combined surgical endovascular approach can be considered as a useful option in inaccessible route.

• 한국해양환경ㆍ에너지학회지
• /
• 제17권3호
• /
• pp.247-256
• /
• 2014

최근, 조류 관측을 위하여 카메라나 레이더 등이 도입되어 보다 정확하고 효율적인 관측이 가능해지게 되었다. 특히, 레이더를 활용하여 조류를 관측하는 방법에 관한 연구가 활발하게 진행되고 있으며, 레이더 조류학이라는 분야가 생겨나게 되었다. 기상 레이더, 공항 탐색 레이더, 추적 레이더 등 여러 종류의 레이더가 조류 관측에 활용되고 있지만, 접근성을 비롯하여 경제성 및 이동성에 많은 제약을 가지고 있어 선박용 레이더가 널리 사용되고 있는 실정이다. 본 논문에서는 선박용 FMCW 레이더를 이용하여 원격 조류 관측 및 통계 분석 기능을 제공하는 시스템 개발에 관한 내용을 다룬다. 이를 위해 널리 알려져 있는 물표 인식을 위한 이미지 처리 기법을 적용하였다. 또한 개발한 시스템을 이용하여 두 차례 실험을 실시하였고, 움직이는 조류가 관측됨을 확인하였다. 그 결과, 각종 레이더 수치 값 조정 등의 개선점을 파악하고 이를 수정하였으며, 조류 관측 분야에 시스템의 적용가능성을 확인하였다. 개발한 시스템은 조류 관측에 관한 연구 뿐 아니라 환경 평가 등의 분야에 도입될 수 있을 것이며, 향후에는 조류 관측을 보다 정확하게 분석하여 통계내고, 조류의 이동 경로를 추적하는 것에 관한 연구가 필요하다.

• 한국환경과학회지
• /
• 제29권6호
• /
• pp.633-641
• /
• 2020

Water temperature is one of the most important factors of fish survival, affecting the habitat, migration route, development, and reproduction. This experiment studied the induction level of heat shock protein (HSP70) mRNA and protein in a walleye pollock (Gadus chalcogrammus) primary hepatocyte culture based on different temperatures. Hepatocytes were attached at 7.5℃ for 24 hours. Hsp70 induction levels were then measured for 48 hours at 5, 8, 11, 14, and 17℃. The induction level was lowest at 5℃ and generally increased with temperature until 14℃. The induction level was reduced at 17℃, indicating that 14℃ is the highest tolerable temperature for hepatocytes. These data indicate that primary hepatocyte cell culture is under no stress at 5 and 8℃. Temperatures greater than 11℃ induce stress, showing similar induction patterns in both mRNA and protein in hepatocytes. The results suggest that 14℃ is the maximum internal defense temperature of walleye pollock survival.

• BMB Reports
• /
• 제45권4호
• /
• pp.233-238
• /
• 2012

We present a top down separation platform for yeast ribosomal proteins using affinity chromatography and capillary electrophoresis which is designed to allow deposition of proteins onto a substrate. FLAG tagged ribosomes were affinity purified, and rRNA acid precipitation was performed on the ribosomes followed by capillary electrophoresis to separate the ribosomal proteins. Over 26 peaks were detected with excellent reproducibility (<0.5% RSD migration time). This is the first reported separation of eukaryotic ribosomal proteins using capillary electrophoresis. The two stages in this workflow, affinity chromatography and capillary electrophoresis, share the advantages that they are fast, flexible and have small sample requirements in comparison to more commonly used techniques. This method is a remarkably quick route from cell to separation that has the potential to be coupled to high throughput readout platforms for studies of the ribosomal proteome.

• Interdisciplinary Bio Central
• /
• 제4권2호
• /
• pp.3.1-3.7
• /
• 2012

Epidermal growth factor receptor (EGFR) is a member of the ErbB family (ErbB1-4) of receptor tyrosine kinases (RTKs). EGFR controls numerous physiological functions, including cell proliferation, migration, differentiation and survival. Importantly, aberrant signaling by EGFR has been linked to human cancers in which EGFR and its various ligands are frequently overexpressed or mutated. EGFR coordinates activation of multiple downstream factors and is subject of various regulatory processes as it mediates biology of the cell it resides in. Therefore, many studies have been devoted to understanding EGFR biology and targeting the protein for the goal of controlling tumor in clinical settings. Endocytic regulation of EGFR offers a promising area for targeting EGFR activity. Upon ligand binding, the activated receptor undergoes endocytosis and becomes degraded in lysosome, thereby terminating the signal. En route to lysosome, the receptor becomes engaged in activating various signaling pathways including PI-3K, MAPK and Src, and endocytosis may offer both spatial and temporal regulation of downstream target activation. Therefore, endocytosis is an important regulator of EGFR signaling, and increasing emphasis is being placed on endocytosis in terms of cancer treatment and understanding of the disease. In this review, EGFR signaling pathway and its intricate regulation by endocytosis will be discussed.

• The Korean Journal of Ecology
• /
• 제24권4호
• /
• pp.219-222
• /
• 2001

The study was conducted to get the basic information for proper protection and management of black-faced spoonbill and their habitats in western coast of South Korea. The species was observed in 8 sites of western coast of South Korea in spring 2000. We confirmed breeding of this species at least 4 pairs in Seokdo island. This island is considered likely to be an imortant breeding site together with Yodo island, Hambakdo island and Yokdo island. Also, we observed breeding of herring gull in Seokdo island and small island nearby Boleumdo island for the first time in South Korea. Chilsando island, Cheonsuman bay and Gyeokyeolbiyeoldo island were considered as stopovers located on the Korean Peninsula route. The other sites were considered as summering sites of the black-faced spoonbill. Especially the birds were constantly observed from breeding season to postbreeding season in Seonduri and Yeochari of Ganghwado island. We have counted maximum 88 individuals gathered at Gaksiyeo in Seonduri and Yeochari on September 3, 2000. The species seemed to gather at these sites after breeding for migration to wintering ground in September. We also surveyed changes of the number of individuals as time of the ebb and flow on September 3 and 6, 2000, their time budgets were affected by the ebb and flow in these sites.

• Fisheries and Aquatic Sciences
• /
• 제27권2호
• /
• pp.76-86
• /
• 2024

The bio-logging method could be a valuable approach to studying the underwater movement of marine fish. We investigated the horizontal and vertical movement patterns of two yellowtails Seriola quinqueradiata weighing 8.7 kg and 9.5 kg with a popup satellite archival tag from October 2020 to January 2021 in the East Sea of Korea. Our results showed that a yellowtail migrated northward in October and November, and then shifted southward in mid-December. The average swimming depth and temperature of the fish monitored over 82 days were 24.9 ± 9.3 m (average ± SD) and 16.5 ± 1.9℃, respectively, and the total traveled distance was 1,172.4 km. The fish swam significantly deeper during the daytime (33.70 ± 14.80 m) than at nighttime (20.65 ± 8.44 m) from November to December (p < 0.05). These results suggest that the horizontal migratory route of yellowtails in accordance with the East Korea Warm Current which is the main branch of Tsushima Warm Current in the fall and early winter seasons, and showed significant diel vertical movement patterns from November to December.

• 한국환경생태학회지
• /
• 제32권5호
• /
• pp.478-485
• /
• 2018

저어새(Platalea minor)는 세계자연보전연맹(IUCN)에서 발표한 RedList에 Endangered(EN)로 지정되어 있으며, 2016년 기준으로 3,356개체가 생존하는 것으로 알려지고 있다. 또한 저어새 번식 개체군의 70% 이상은 한국 서해안에서 번식하며, 대만, 중국, 홍콩 등지에서 월동하는 것으로 알려져 있으나 한국을 비롯하여 동아시아 지역에서 저어새의 장거리 이동과 남하 시 서식지에 대한 연구는 현재까지 거의 이루어지지 않은 실정이다. 이 연구에서는 야생동물위치추적기(WT-200, GPS-Mobile phone based telemetry, KoEco)를 이용하여 저어새의 이동 경로와 분포, 중간기착지 및 월동지를 밝히고자 하였다. 위치추적기는 2014년 6월 말 한국의 번식지에서 저어새 유조를 포획하여 부착했다. 추적 결과, 저어새의 남하시기는 10월 말에서 11월 초로 나타났으며, 월동지까지의 이동 거리는 최소 746km, 최대 1,820 km로 평균 1,201 km이었다. 하루 최대 이동 거리는 1,479 km이었으며, 평균 782 km이었다. 월동지까지 이동소요 기간은 평균 10일이었으며, 가장 짧은 기간은 2일이었고 가장 긴 기간은 34일이었다. 대부분의 개체들은 2~3개의 중간기착지를 이용하였으며, 1~2일을 머물렀으며, 주요 중간기착지는 강, 하천, 저수지, 갯벌과 같은 습지였다. 월동지는 중국 해안 지역(5개체), 중국 내륙 지역(1개체), 대만(3개체), 일본(1개체)등 으로 나타났다. 결론적으로 저어새의 이동경로 상에 있는 국가 간의 협의와 보호정책을 통해 이들이 주로 이용하는 중간기착지 및 월동지역을 보전할 필요가 있으며, 향후 지속적인 모니터링과 추가연구를 통해 체계적인 보전대책 및 활동계획 등이 수립되어야 할 것으로 판단된다.

• 한국측량학회지
• /
• 제25권3호
• /
• pp.257-266
• /
• 2007

적조에 관한 조사는 육안과 샘플링에 의한 현지조사에 의해 일반적으로 진행되고 있다. 이와 같은 기존의 조사, 분석방법은 적조의 발생과 소멸까지의 경로를 정확하게 예측하기 곤란하였다. 이에 좀더 객관적이고 과학적인 방법으로 적조의 발생과 그 이동경로 등 시 공간적인 환경인자를 분석해 볼 필요성이 대두되고 있다. 본 연구에서는 지리정보시스템을 적용하여 적조의 공간특성을 분석하고자 Arc/Info를 활용하여 자료를 구축한 후 적조발생해역에서의 적조밀도분포를 추정하기 위해 IDW 보간법을 적용하였다. 그 후 GRID 모듈의 CON 및 SUM Function을 이용하여 밀도 1,000cells/ml이상 발생된 해역을 추출하였으며, 추출된 해역을 기준으로 날짜별로 밀도를 누적하였다. 본 연구를 통하여 적조가 발생되는 해역을 지리정보시스템에 의해 적조의 분포 현황을 시 공간적으로 판단할 수 있었으며, 적조발생지의 공간별 밀도와 누적빈도를 GIS를 적용하여 분석한 결과 최대밀도 발생해역과 최대 빈도 발생해역 모두 남해도 남면일대 해역으로서 최대 누적빈도는 49회임을 알 수 있었다. 이를 근거로 차 후 발생되는 적조발생해역에 대한 자료의 보완이 이뤄질 경우 적조 발생과 소멸까지의 이동경로를 예측 할 수 있으리라 판단된다.