• International Journal of Contents
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• 제5권4호
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• pp.13-18
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• 2009

The existence of Korean schools is one of the salient characteristics of Overseas Koreans. How do such schools for Korean immigrants' children try to construct Korean ethnic identity? Also, how is immigrant children's ethnic identity developed and reinforced by the education at those schools? This paper explores these questions based on an ethnographic research at a Korean school in Paris from September 2005 to December 2007. The cultural education for immigrant children at the Korean school has a tendency to emphasize the most exotic traits of Korean culture. And this emphasis on the unfamiliar elements of Korean culture doesn't seem to help to form the ethnic identity of Korean immigrants' children. Instead, the students appear to get the sense of being a member of Koreans more from the education outside of classroom such as scholastic events than in a classroom of a Korean school. That's because scholastic events allow them to play out some of the Korean culture in more inter-ethnic settings. Therefore, it can be concluded that ethnicity of immigrant children is rather developed in inter-ethnic social contexts than born with or taught in class.

• 한국식품조리과학회지
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• 제7권1호
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• pp.1-9
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• 1991

The purpose of this study is to investigate the management of Indigenous fermented foods during the period of economic development starting from 1960 until now, and to specify their correlation, while paying special concern to the variables of social change such as the increase of people's income, ceaseless migration of population, change in the family structure, heightening up of the educational level of women and the resulting increase of chances for getting employment, all of which may affect the management of Indigenous fermerted foods in korean families. The result is as follows. Basic seasonings and dishes such as soy bean sauce, red pepper paste, pickled seafoods, and Kimchi, are inclined to be bought as readymade products or provided by relatives in case of many nuclear families rather than made at home, which is a traditional way of home life. However, Kimchi and basic sauces or redpepper paste still show high rate of being made at home. Social variables which affect such tendency are the number of family members, the age and educational level of housewife, and the type of residence.

• Bulletin of the Korean Chemical Society
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• 제29권5호
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• pp.1013-1017
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• 2008

Syndecan-3 is a cell-surface heparan sulfate proteoglycan, which performs a variety of functions during cell adhension process. It is also a coreceptor for growth factor, mediating cell-cell and cell-matrix interaction. Syndecan-3 contains a cytoplasmic domain potentially associated with the cytoskeleton. Syndecan-3 is specifically expressed in neuron cell and has related to neuron cell differentiation and development of actin filament in cell migration. Syndecans each have a unique, central, and variable (V) region in their cytoplasmic domains. And that region of syndecan-3 may modulate the interactions of the conserved C1 regions of the cytoplasmic domains by tyrosine phosphorylation. Cytoplasmic domain of syndecan-3 has been synthesized for NMR structural studies. The solution structure of syndecan-3 cytoplasmic domain has been determined by two-dimensional NMR spectroscopy and simulated-annealing calculation. The cytoplasmic domain of the syndecan proteins has a tendency to form a dimmer conformation with a central cavity, however, that of syndecan-3 demonstrated a monomer conformation with a flexible region near C-terminus. The structural information might add knowledge about the structure-function relationships among syndecan proteins.

• E2M - 전기 전자와 첨단 소재
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• 제10권7호
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• pp.659-667
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• 1997

The influence of SiO$_2$on the microstructure and electrical properties of zinc oxide varistor was investigated. Zn$_2$SiO$_4$third phase in the sintered body was found at grain boundaries, multiple grain junctions, and occasionally within ZnO grains. This phase acted as a grain growth inhibitor, which retard the grain growth of the ZnO matrix by impeding migration on the grain boundaries. As SiO$_2$ addition increases, average grain size decreased from 40.6${\mu}{\textrm}{m}$ to 26.9${\mu}{\textrm}{m}$ due to the pinning effect by Zn$_2$SiO$_4$ and drag effect by Si segregation at grain boundaries, the breakdown voltage consequently increased. When SiO$_2$ addition is increased, interface state density decreased, however, the barrier height increased by decrease of donor concentration, as a result, the nonlinear exponent increased and leakage current decreased. While, as SiO$_2$ addition increase, it was found that the apparent dielectric loss factor shows a tendency of decrease. Wholly, electrical properties of zinc oxide varistor can be said to be improved by SiO$_2$addition.

• Parasites, Hosts and Diseases
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• 제22권2호
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• pp.181-189
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• 1984

우리나라산(전남 강진 및 경남 금해시)미꾸리에서 이전고무극구흡충(Echinostoma cinetorchis)의 피낭유충을 처음으로 검출하고 횐쥐에 감염시킨 후 성충을 얻어 종을 확인하였다. 또, 미꾸리의 피낭유충 감염상황과 횐쥐에서의 간단한 발육과정을 관찰하였다. 결과를 요약하면 다음과 같다. 1. 미꾸리 46마리중 5마리 (10.9%)에서 담낭유충이 검출되었고 감염된 미꾸리당 감염대은 평균 34.4개이었다. 피낭유충은 미꾸리의 후복벽에서만 발견되었다. 2. 실험감염 횐쥐에서 감염 6∼28일까지 총 충체회수률은 24.6%이었으며 감염기간이 길어짐에 따라 회수률은 감소되었다. 3. 충체는 두증과 두련(37∼38개)이 뚜렷하고 고환이 이전하거나 소실되는 점으로 보아 E. sinetorchis Ando et Ozaki, 1923로 동정되었다. 4. 충체의 발육은 감염6일부터 10일 사이에 가장현저하였으며 이 기간중 특히 생식기관의 발육이 비생식기관에 비해 빠르고 현저하였다. 이상의 결과로 볼 때 우리나라에서 미꾸리가 이전고구극구흡충의 제이중간숙주 역할을 하고 있음이 입증되었고 실험적으로 얻은 성충의 형태에서 고구의 이전 또는 소실이 종의 특성임이 재확인되었다.

• Molecules and Cells
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• 제39권12호
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• pp.898-908
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• 2016

Despite recent groundbreaking advances in multiple myeloma (MM) treatment, most MM patients ultimately experience relapse, and the relapse biology is not entirely understood. To define altered gene expression in MM relapse, gene expression profiles were examined and compared among 16 MM patients grouped by 12 months progression-free survival (PFS) after autologous stem cell transplantation. To maximize the difference between prognostic groups, patients at each end of the PFS spectrum (the four with the shortest PFS and four with the longest PFS) were chosen for additional analyses. We discovered that integrin-${\alpha}8$ (ITGA8) is highly expressed in MM patients with early relapse. The integrin family is well known to be involved in MM progression; however, the role of integrin-${\alpha}8$ is largely unknown. We functionally overexpressed integrin-${\alpha}8$ in MM cell lines, and surprisingly, stemness features including $HIF1{\alpha}$, VEGF, OCT4, and Nanog, as well as epithelial mesenchymal transition (EMT)-related phenotypes, including N-cadherin, Slug, Snail and CXCR4, were induced. These, consequently, enhanced migration and invasion abilities, which are crucial to MM pathogenesis. Moreover, the gain of integrin-${\alpha}8$ expression mediated drug resistance against melphalan and bortezomib, which are the main therapeutic agents in MM. The cBioPortal genomic database revealed that ITGA8 have significant tendency to co-occur with PDGFRA and PDGFRB and their mRNA expression were up-regulated in ITGA8 overexpressed MM cells. In summary, integrin-${\alpha}8$, which was up-regulated in MM of early relapse, mediates EMT-like phenotype, enhancing migration and invasion; therefore, it could serve as a potential marker of MM relapse and be a new therapeutic target.

• 한국수산과학회지
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• 제4권1호
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• pp.7-16
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• 1971

1970년 5월, 7월, 12월에 우리나라 동해안에서 어획된 꽁치에 대해서 척추골수, 새파수 및 상대성장을 조사한 결과를 요약하면 다음과 같다. 1. 척추골수는 65개를 mode로 하고 $64\~66$게가 전체의 $90\%$ 내외를 차지하고 있으며, 평균 척추골수는 64.80이다. 새파수는 12월에 있어서 $33\~44$개의 범위에 있으며 평균치는 37.08이다. 2. 중형군($26.0\~28.0cm$대)과 대형군($30.0\~31.0cm$대)으로 구분하여 척추골수라 새파수를 보면 북상기의 중형군은 남하기의 대형군과 그 수가 닮아 있고 남하기의 중형군은 북대기의 대형군과 그 수가 닮아 있다. 3. 척추골수와 새파수와의 사이에는 상관이 보이지 않는다. 그러나, 12월에 있어서 척수골수는 대형군이 중형군보다 많으나 새파수는 중형군이 대형군보다 많다. 4. 체장에 따른 두장비의 변화는 체장의 증가에 따라 감소되는 경향이다. 5. 체장과 두장과의 관계 및 체장과 체중과의 관계는 북상기와 남하기에 따라 그 경향이 다르다. 6. 7월의 중형군에서 12월의 대형군까지의 체중 증가량은 12월의 중형군에서 7월의 대형군까지의 체중 증가량의 약 2배 이상이 될 것이라 추정된다. 7. 체장에 따른 비만도(내장 제외한 체중으로 계산)는 12월에서는 거의 일정하나, 7월의 손 꽁치 어업에서 어획되는 산란중의 군중에서는 중형군과 대형군이 상이하다. 그리고, 12월의 비만도는 7경의 비만도보다 높다.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제35권2호
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• pp.112-119
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• 2009

Extracellular matrix(ECM) is known to function as a reservoir of endogenous growth factors, can be an effective delivery system of growth factor that easily lost bioactivity in solution. Fibrillar collagens like type I collagen, are the major constituent of the ECM and structural protein of bone. Also, it can be a scaffold for osteoblast migration. The purpose of this study was to compare the effects of absorbable Atelo-collagen Sponge($Teruplug^{(R)}$) insertion in tooth extraction sites on periodontal healing of the mandibular second molar after the extraction of the impacted third molar. The study population comprised 31 cases who had been scheduled for surgical removal of impacted mandibular third molars. All patients were in good general health and were not using any medication that would influence wound healing after surgery. In 15 cases control group, none was inserted into the tooth extraction site. In 16 cases experimental groups, $Teruplug^{(R)}$ was inserted into the tooth extraction site. We evaluated tooth mobility, pocket depth, gingival margin level preoperatively and 1 week, 2 weeks, 4 weeks, and 3 months postoperatively. The change was compared with two groups using Mann-Whitney test. The results were as follows. 1. There was no significant change of tooth mobility on both groups. 2. There was tendency of decreasing of previous pocket depth causing tooth extraction on both groups. 3. On gingival margin level, there was various change according to initial swelling and loss of attachment on both groups. 4. There was tendency of decreasing of gingival margin level on both groups because of removal of inflammation and decreasing of previous pocket depth. 5. There was large change of pocket depth on buccal middle, distal, lingual distal area because of tooth extraction and bone reduction. Compared with the control group and experimental group, we observed significant difference during some periods. The results of this study suggest that absorbable atelo-collagen sponge($Teruplug^{(R)}$) is relatively favorable bone void filler with prevention of tissue collapse, food packing and enhance periodontal healing.

• International Journal of Oral Biology
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• 제32권3호
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• pp.93-101
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• 2007

Cell behavior of the transformed cells is known to affect by interaction with extracellular matrix (ECM) proteins and integrin. To investigate the alterations of both integrin expression and cell-matrix interaction during neoplastic conversion of human oral kerationcytes, we studied expression levels of integrin subunits by flow cytometry and cellular responses to the ECM proteins in normal human oral keratinocytes (NHOKs), HPV-immortalized HOK-16B line, and three oral cancer cell lines established from HOK-16B line, CTHOK-16B-BaP, CTHOK-16B-DMBA, and CTHOK-16B-Dexa lines. The expression levels of ${\alpha}\;and\;{\beta}$ integrin subunits were shown decreased tendency in human oral keratinocytes undergoing immortalization and tumorigenic transformation except CTHOK-16B-DMBA line tested. Although ${\alpha}v{\beta}6$ integrin is known to be highly expressed in squamous cell carcinomas, and the altered integrin expression is suspected to be associated with cellular carcinogenesis, ${\alpha}v$ integrin subunit and ${\alpha}v{\beta}6$ integrin did not express in oral cancer cell lines tested. Cell behavior to the ECM proteins in HOK-16B line was generally similar to that of exponentially proliferating NHOKs. The adhesion activity profiles of type I collagen were very similar to that of its laminin counterparts, but fibronectin showed minimal adhesion activity under our conditions compared to the BSA control. The ability of the CTHOK-16B-BaP line to spread upon type I collagen and laminin markedly decreased, but migration was notably increased on type I collagen. In contrast, CTHOK-16B-DMBA and CTHOK-16B-Dexa lines spread less but migrated more upon type I collagen than immortalized HOK-16B line. These data indicate that downregulation of integrin subunits causes the changes of cellular responses to the ECM proteins during neoplastic conversion of human oral keratinocytes, and that cellular responses to the ECM proteins in oral cancer cell lines established by exposing different carcinogens are variable according to chemical carcinogens treatment.

• 한국건축시공학회지
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• 제9권6호
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• pp.71-78
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• 2009

하중을 고려한 염분침투성의 평가가 대단히 중요한 것으로 확인되었다. 본 연구에서는 압축응력하에서 Plain콘크리트에서는 47%정도, BFS콘크리트에서는 89%정도 증가 하는 것으로 나타났다. 무하중 상태에서 BFS를 혼입한 콘크리트의 확산계수가 BFS 무혼입 콘크리트에 비해 적은 것이 확인되었다. 이러한 영향은 압축응력이 발생하는 환경하에서도 같은 경향을 나타내었다. 압축응력이 작용하는 환경 하에서 BFS콘크리트는 Plain콘크리트와 같이 하중의 증가와 함께 확산계수가 증가하는 것으로 확인 되었다. 또한, Plain콘크리트에 비해 압축하중의 영향을 크게 받는 것으로 확인 되었다. BFS의 비표면적이 높을수록 확산 계수가 작은 것으로 확인되었고, 이러한 경향은 고응력 환경에서 현저히 나타나는 것이 확인되었다. BFS의 치환율이 증가할수록 확산계수가 작은 것이 확인되었다. 또한, 압축응력이 작용하는 환경 하에서 BFS의 치환에 의한 염분침투성의 억제 효과가 더욱 더 현저히 나타나는 것으로 확인되었다.