• International Journal of Advanced Culture Technology
• /
• v.12 no.1
• /
• pp.43-50
• /
• 2024

Patients with acute respiratory diseases, such as Middle East Respiratory Syndrome (MERS) due to COVID-19, must wear masks, protective clothing, face shields, and gloves to prevent infection during treatment and performance. Even if it is applied to disabled people, families who protect them are severely mentally tired from severe physical fatigue and stress from exposure to high-risk infectious diseases. As such, the spread of infectious diseases such as respiratory diseases has not only caused difficulties in using existing welfare and medical services but also caused various problems throughout the daily life of disabled people due to the prolonged infectious disease, and its scope is gradually expanding. Therefore, it should not be overlooked that disabled people may experience various difficulties, from the spread of infectious diseases such as respiratory diseases to isolation, diagnosis, and treatment, and it is time to actively assess the life changes felt by families caring for disabled people and consider and research to provide adequate services. According to the survey of disabled people is being conducted in the context of the spread of infectious diseases such as respiratory diseases, while research on the spread of infectious diseases such as respiratory diseases is rare for parents with disabilities. There is a need for additional investigation into the characteristics in other areas of everyday life, including the health field, which is deteriorating through prior research. Therefore, through this survey, the purpose of this study is to investigate the life changes of parents with disabilities in the context of the spread of infectious diseases such as respiratory diseases and to compare and analyze them to find out how parents were affected by each type of disability. It will be used as evidence to identify more necessary needs and problems for parents with disabilities in the spread of infectious diseases such as respiratory diseases and to provide more appropriate health care and welfare services in the future.

• Journal of the Korean Data and Information Science Society
• /
• v.28 no.2
• /
• pp.297-307
• /
• 2017

The epidemic model is used to model the spread of disease and to control the disease. In this research, we utilize SEIR model which is one of applications the SIR model that incorporates Exposed step to the model. The SEIR model assumes that a people in the susceptible contacted infected moves to the exposed period. After staying in the period, the infectee tends to sequentially proceed to the status of infected, recovered, and removed. This type of infection can be used for research in cases where there is a latency period after infectious disease. In this research, we collected respiratory infectious disease data for the Middle East Respiratory Syndrome Coronavirus (MERSCoV). Assuming that the spread of disease follows a stochastic process rather than a deterministic one, we utilized the Poisson process for the variation of infection and applied epidemic model to the stochastic chemical reaction model. Using observed pandemic data, we estimated three parameters in the SIER model; exposed rate, transmission rate, and recovery rate. After estimating the model, we applied the fitted model to the explanation of spread disease. Additionally, we include a process for generating the Exposed trajectory during the model estimation process due to the lack of the information of exact trajectory of Exposed.

• Research in Community and Public Health Nursing
• /
• v.29 no.1
• /
• pp.65-75
• /
• 2018

Purpose: This study aims to examine how elementary, middle and high school health teachers in Gyeonggi province react to infectious disease like MERS. Methods: This is a descriptive study using a convenience sample of 1,267 school health teachers. Results: When MERS was an epidemic, school health teachers who took the 'leading' role were 92.4%. A school heath teacher's countermeasures against infectious diseases showed a high score during MERS outbreak (3.81) compared to regular days (3.59). Conclusion: Based on such results, it has been determined that schools need to keep two types of procedures manual, such as 'countermeasures on a regular basis' and 'countermeasures in the event of a pandemic disease outbreak' manual in the staff offices so that anyone can view them at any time. It is necessary to prepare regulations to strengthen their authority so that school health teachers can take the role of control tower, in a professional capacity, when communicable disease is spreading. In order to prevent any confusion and chaos, there should be a unitary reporting system at each school when dealing with an epidemic. School health teachers need to get continuous training to reinforce their abilities to react to communicable diseases.

• Journal of Contemporary Eastern Asia
• /
• v.16 no.1
• /
• pp.69-81
• /
• 2017

This study examines how South Korean governments responded to the outbreak of Middle East Respiratory Syndrome Coronavirus (MERS) using the adaptive governance framework. As of November 24, 2015, the MERS outbreak in South Korea resulted in the quarantine of about 17,000 people, 186 cases confirmed, and a death of 38. Although the national government had overall responsibility for MERS response, there is no clear understanding of how the ministries, agencies, and subnational governments take an adaptive response to the public health crisis. The paper uses the adaptive governance framework to understand how South Korean governments respond to the unexpected event regarding the following aspects: responsiveness, public learning, scientific learning, and representativeness of the decision mechanisms. The framework helps understand how joint efforts of the national and subnational governments were coordinated to the unexpected conditions. The study highlights the importance of adaptive governance for an effective response to a public-health related extreme event.

• Biomolecules & Therapeutics
• /
• v.31 no.4
• /
• pp.370-387
• /
• 2023

The COVID-19 pandemic has increased demand for safe and effective vaccines. Research to develop vaccines against diseases including Middle East respiratory syndrome, Ebolavirus, human immunodeficiency virus, and various cancers would also contribute to global well-being. For successful vaccine development, the advancement of technologies such as antigen (Ag) screening, Ag delivery systems and adjuvants, and manufacturing processes is essential. Ag delivery systems are required not only to deliver a sufficient amount of Ag for vaccination, but also to enhance immune response. In addition, Ag types and their delivery systems determine the manufacturing processes of the vaccine product. Here, we analyze the characteristics of various Ag delivery systems: plasmids, viral vectors, bacterial vectors, nanoparticles, self-assembled particles, natural and artificial cells, and extracellular vesicles. This review provides insight into the current vaccine landscape and highlights promising avenues of research for the development and improvement of Ag delivery systems.

• Biomolecules & Therapeutics
• /
• v.32 no.2
• /
• pp.262-265
• /
• 2024

• The Korean Society of Law and Medicine
• /
• v.16 no.2
• /
• pp.263-291
• /
• 2015

In May, 2015, a 68 years old man, who has been Middle East Saudi Arabia and the United Arab Emirates, had high fever, muscle aches, cough and shortness of breath. he went two local hospital near his house and the S Medical Center emergency center. He was diagnosed MERS(Middle East respiratory syndrome) and the diseases had put South Korea the fear of epidemics for three months. Especially, this disease has firstly reported in Middle East Asia in September 2012 and spreaded to twenty-six countries. In 21, July, 2015, European Center for disease prevention and control reported 533 people were died and in South Korea, 186 people were infected, 36 people were died and 16,693 people were isolated from MERS. South Korea government were faced into epidemic control and blamed from public. Especially, hospital acquired infection, disease control chain, opening of information, ventilation, lack of isolation bed, the problem of function of local health center, the issue of reparation for hospital and insurance cover rate, the classification of disease, the role of Korea Centers for disease control and prevention, the culture of visiting hospital to see sick people, the issue of hospital multiple room and other related social support policy. it is time to study and discuss to solve these problems. South Korea citizens felt fear and fright from MERS. What is wore, they thought the dieses were out of their government control. It was unusual case for word except Middle East Asia. numerous tourists canceled visiting korea. South korea economic were severly damaged especially, tourism industry. South korea government should admit that they had failed initial action against MERS and take full reasonability from any damages. The government have to open information to public in terms of epidemic diseases and try to prevent any other epidemic diseases and try to work with local governments.

• Korean Journal of Clinical Pharmacy
• /
• v.27 no.1
• /
• pp.9-14
• /
• 2017

Background: Pharmacy curriculum change was made from a 4-year program to a 2+4 year program in year 2009 in Korea. The change has resulted in more educational exposures on patient-centered practice environments for about 1,400 hours in the last year of the professional pharmacy program. When the Middle East Respiratory Syndrome (MERS) outbreak hit Seoul and suburban areas and propagated to other provinces in Korea, emergency response to avoid student infection in the pharmacy practice sites became an urgent issue. While other health professional programs such as medicine and nursing had activated emergency preparedness manuals, timely and clear guidelines were not disseminated to all pharmacy programs and protective measures largely relied on individual pharmacy program. Methods: A survey was developed by the Committee on Pharmacy Practice Experience Programs in the Korean College of Clinical Pharmacy to document the status of pharmacy programs during the Korea MERS outbreak in 2015. The 10-question survey was distributed to the pharmacy practice experience coordinators to 34 out of 35 pharmacy schools in Korea by emails. Results: Our findings showed that 82.4% of the program coordinators (28/34) responded to the survey, 96.4% of the programs did not have emergency preparedness manuals, administrative meetings were held in 89.3% of the pharmacy programs, the rotation schedules were modified or withheld in 53.6% of schools, and the changes were mostly observed from the programs classified as MERS outbreak regions. Conclusion: Further needs in establishing the emergency preparedness manual should be explored for pharmacy education stakeholders.

• Journal of the Korea Academia-Industrial cooperation Society
• /
• v.19 no.9
• /
• pp.174-185
• /
• 2018

This study was conducted to explore the levels of Middle East Respiratory Syndrome (MERS)-related knowledge, attitudes and preventive behaviors performance and to identify predictors of MERS-related preventive behaviors performance among clinical practice students in a tertiary hospital. The participants were 480 nursing and medical clinical practice students. Data collection was conducted using self-reported questionnaires in June of 2015 and were analyzed using descriptive statistics, independent t-tests, one-way ANOVA, and hierarchical regression using the SPSSWIN 24.0 program. The MERS-related knowledge (9.56 out of 13 points) was high, attitudes towards MERS, such as severity cognition and prevention about MERS was positive (4.15 out of 5 points), and MERS-related preventive behaviors performance level was moderate (3.02 out of 5 points). Female students, having education experience regarding MERS, taking vaccination for influenza H1N1 infection in the last year, having the intention of taking influenza H1N1 in the current year, having fear of MERS infection, higher knowledge and more positive attitudes about MERS were predictors of better MERS-related preventive behaviors performance. These results show that general characteristics associated with MERS-related preventive behaviors performance should be considered to improve preventive behaviors of clinical practice students. Furthermore, this study highlights the need to develop effective and useful MERS education programs that provide essential knowledge and attitude about MERS that clinical practice students must acquire to promote the MERS-related preventive behaviors performance.

• IMMUNE NETWORK
• /
• v.21 no.1
• /
• pp.11.1-11.10
• /
• 2021

Coronavirus causes an infectious disease in various species and crosses the species barriers leading to the outbreak of zoonotic diseases. Due to the respiratory diseases are mainly caused in humans and viruses are replicated and excreted through the respiratory tract, the nasal fluid and sputum are mainly used for diagnosis. Early diagnosis of coronavirus plays an important role in preventing its spread and is essential for quarantine policies. For rapid decision and prompt triage of infected host, the immunochromatographic assay (ICA) has been widely used for point of care testing. However, when the ICA is applied to an expectorated sputum in which antigens are present, the viscosity of sputum interferes with the migration of the antigens on the test strip. To overcome this limitation, it is necessary to use a mucolytic agent without affecting the antigens. In this study, we combined known mucolytic agents to lower the viscosity of sputum and applied that to alpha and beta coronavirus, porcine epidemic diarrhea virus (PEDV) and Middle East respiratory syndrome coronavirus (MERS-CoV), respectively, spiked in sputum to find optimal pretreatment conditions. The pretreatment method using tris(2-carboxyethyl)phosphine (TCEP) and BSA was suitable for ICA diagnosis of sputum samples spiked with PEDV and MERS-CoV. This sensitive assay for the detection of coronavirus in sputum provides an useful information for the diagnosis of pathogen in low respiratory tract.