• Archives of Plastic Surgery
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• 제51권5호
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• pp.504-509
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• 2024

The treatment of breast cancer has seen great success in the recent decade. With longer survivorship, more attention is paid to function and aesthetics as integral treatment components. However, breast cancer-related lymphedema (BCRL) remains a significant complication. Immediate lymphatic reconstruction is an emerging technique to reduce the risk of BCRL, the Lymphatic Microsurgical Preventive Healing Approach (LYMPHA) being the most widely used approach. Despite promising results, it is often difficult to find suitably sized recipient venules and perform the micro-anastomoses between mismatched vessels deep in the axilla. Moreover, high axillary venous pressure gradients and potential damage from radiotherapy may affect the long-term patency of the anastomoses. From an ergonomic point of view, performing lymphaticovenular anastomosis in the deep axilla may be challenging for the microsurgeon. In response to these limitations, we modified the technique by moving the lymphatic reconstruction distally-terming it distally based LYMPHA (dLYMPHA). A total of 113 patients underwent mastectomy with axillary clearance in our institution from 2018 to 2021. Of these, 26 underwent subsequent dLYMPHA (Group 2), whereas 87 did not (Group 1). In total, 17.2% (15 patients) and 3.84% (1 patient) developed BCRL in Groups 1 and 2, respectively (p = 0.018). Lymphatics and recipient venules suitable for anastomoses can be reliably found in the distal upper limb with better size match. A distal modification achieves a more favorable lymphaticovenular pressure gradient, vessel match, and ergonomics while ensuring a comparably low BCRL rate.

• Archives of Plastic Surgery
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• 제51권5호
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• pp.474-479
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• 2024

The introduction of nonabsorbable barbed sutures in plastic surgery has allowed the achievement of significant results in terms of efficacy and short- and long-term outcomes. However, a nonabsorbable material with no antibacterial coating could act as a substrate for subclinical bacterial colonization and thereby determine recurrent subacute and chronic infective-inflammatory processes. The authors report a clinical experience of subacute infectious complications after two cases of diastasis recti surgical correction. The authors present a two-case series in which a nonabsorbable barbed suture was used for the repair of diastasis recti. The postoperative course was complicated by surgical site infection. The origin of the infectious process was clearly localized in the fascial suture used for diastasis correction. The suture was colonized by bacteria resulting in the formation of multiple granulomas of the abdominal wall a few months postoperatively. In both the reported cases, the patients partially responded to the antibiotic targeted therapy and reoperation was required. The microbiological analyses confirmed the colonization of sutures by Staphylococcus aureus. Barbed nonabsorbable sutures should be avoided for diastasis recti surgical correction to minimize the risk of infectious suture-related complications. The paper's main novel aspect is that this is the first clinical report describing infectious complications after surgical correction of diastasis recti with barbed polypropylene sutures. The risk of microbiological subclinical colonization of polypropylene suture untreated with antibacterial coating, therefore, should be taken into account.

• Journal of Cerebrovascular and Endovascular Neurosurgery
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• 제25권4호
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• pp.462-467
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• 2023

Thrombectomy procedures following intra-aneurysmatic lesions are extremely rare, and few cases have been reported. This article describes a microsurgical intra-aneurysmatic thrombectomy (MIaT) for a distal anterior cerebral artery (DACA) aneurysm. We present the case of a 48-year-old female that was admitted to the emergency room, showing neurologic deterioration with focal deficits. A computed tomography angiography (CTA) scan revealed an aneurysm located in the distal segment of the left anterior cerebral artery. During the surgical procedure, after clipping, a well-formed clot was visualized through the aneurysm's wall obstructing the left DACA flow. We proceeded to open the aneurysm's dome to remove the thrombus and clip the aneurysm neck, re-establishing the flow of the left DACA. Intra-aneurysmatic thrombosis can occur as a complication during clipping, obstructing the distal flow of vital arteries and causing fatal results in the patient's postoperative status. MIaT is a good technique for restoring the flow of the affected vessel and allows a secure aneurysm clipping after thrombus removal.

• Journal of Cerebrovascular and Endovascular Neurosurgery
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• 제25권2호
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• pp.150-159
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• 2023

Objective: The aim of this study was to investigate the efficacy of intraoperative indocyanine green videoangiography (ICG-VA) and intraoperative neuromonitoring (IONM) to prevent postoperative ischemic complications during microsurgical clipping of unruptured anterior choroidal artery (AChA) aneurysms. Methods: We retrospectively reviewed the clinical and radiological records of all patients who had undergone microsurgical clipping for unruptured AChA aneurysms at our institution between April 2001 and December 2019. We compared the postoperative complication rate of the group for which intraoperative ICG-VA and IONM were utilized (group B; n=324) with that of the group for which intraoperative ICG-VA and IONM were not utilized (group A; n=72). Results: There were no statistically significant differences in demographic data between the two groups. Statistically significant differences were observed in the rate of overall complications (p=0.014) and postoperative ischemic complications related to AChA territory (p=0.039). All the cases (n=4) in group B who had postoperative infarctions related to AChA territory showed false-negative results of intraoperative ICG-VA and IONM. Conclusions: Preserving the patency of the AChA is essential to minimize postoperative complications. Intraoperative monitoring tools including ICG-VA and IONM can greatly contribute to lowering complication rates. However, their pitfalls and false-negative results should always be considered.

• Journal of Cerebrovascular and Endovascular Neurosurgery
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• 제25권4호
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• pp.475-484
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• 2023

Objective: This study aimed to develop microsurgical strategies based on the anatomical relationship between dorsal internal carotid artery (ICA) aneurysms, the falciform ligament (FL), and the anterior clinoid process (ACP). Methods: Between 2017 and 2022, 25 patients with unruptured dorsal ICA aneurysms (less than 4 mm in diameter) underwent microsurgical direct clipping. These cases involved the left ICA (n=17) and the right ICA (n=8), with a mean aneurysm size of 3.3 mm (range, 2.5 to 4 mm). We used computed tomography angiography (CTA) and digital subtraction angiography to elucidate the anatomical relationship between dorsal ICA aneurysms and other structures. All procedures involved an ipsilateral pterional approach with securement of the ipsilateral cervical ICA for proximal control. Results: Among the 25 dorsal ICA aneurysms, 8 (32%) were clipped without the FL being incised. Another 5 (20%) were clipped solely after the FL was cut. For the remaining 12 cases, the aneurysms were successfully clipped following FL incision and partial ACP removal. Patients exhibited favorable postoperative recoveries with good outcomes, and postoperative CTA revealed complete aneurysm clipping without any residual remnants. Conclusions: We were able to perform clipping without removing the ACP in 13 patients (52%), and in 8 of these (32%), the clipping was carried out directly without cutting the FL. Microsurgery, coupled with proximal control of the cervical ICA, can serve as a viable alternative for patients with small dorsal ICA aneurysms, especially when endovascular treatment options are limited, and 3D CTA confirms a clear anatomical relationship with the ACP.

• Journal of Cerebrovascular and Endovascular Neurosurgery
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• 제26권2호
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• pp.216-222
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• 2024

Dissecting posterior inferior cerebellar artery (PICA) aneurysms are uncommon lesions. Their anatomy and the location of the dissection are variable, however, they usually occurs at the origin of the PICA. Dissecting PICA aneurysms generally have non-vascular morphology involving an entire segment of the artery and cannot be cut. Nevertheless, the detection of these vascular lesions has increased latterly, so it is necessary to recognize it and take the appropriate management modalities for these injuries. In this report, we describe a case of a 73-year-old male patient, who presented a history of severe headache, associated with neck stiffness, nausea, vomiting, dizziness, hypoactivity, mental confusion, and walking difficulty. Radiographic investigation with brain computed tomography (CT) showed mild bleeding in a pre-medullary and pre-pontine cistern, and cerebral angiogram showed a dissecting PICA aneurysm. Despite being a challenging treatment, microsurgery management was the chosen modality. It was performed an end-to-end anastomosis between the p2/p3 segments, showing to be effective with good clinical and radiographic outcomes. We discussed an unusual case, reviewing the current literature on clinical presentations, the angiographic characteristics of the dissecting aneurysms of PICA, and evaluating the clinical and angiographic results of patients undergoing microsurgical treatment.

• Archives of Reconstructive Microsurgery
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• 제5권1호
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• pp.137-146
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• 1996

서울대학교 의과대학 정형외과학 교실에서는 1985년 1월부터 1994년 12월까지 치험하였던 103명의 환자를 대상으로 최소한 8개월간 보존적 치료를 시행하며 자연 회복을 기다렸고, 수상 후 8개월에서 10개월까지 3개월마다 반복된 근전도 검사상 회복이 없거나 경미한 31명에 대하여 신경 복원술을 시행하여 다음과 같은 결과를 얻었다. 1) 자연 회복은 상완 신경총 손상 환자의 47명(46%)에서 일어났으며, 자연 회복된 환자의 3분의 2(31명)에서 근전도 검사상의 변화가 3개월에서 9개월 사이에 처음 발견되었고, 나머지 3분의 1(16명)의 환자에서 9개월에서 16개월 사이에 발견되어, 평균 7.8개월에 시작됨을 보여주었다. 수정된 AMA score상 내원 당시 14.8점에서 최종 추시 관찰시 39.8점으로 개선되었다. 2) 신경 복원술을 실시한 31명 중 52%가 기능적 호전을 보여주었고 수정된 AMA score상 술전 21.5점에서 술후 36.3점으로 14.8점이 개선되었다. 3) 양군에서 기능적 호전을 보인 비율은 유의한 수준이 아니지만, 기능적 호전의 정도는 25점과 14.8점으로 자연 회복군이 신경 복원술을 실시한 군보다 통계적으로 더 우수한 기능적 호전을 보임을 알 수 있었다(p<0.05). 4) 결국 저자들은 현재까지 손상의 부위와 정도를 정확하게 진단할 수 있는 방법이 부족한 상태에서 이론적으로 많은 문제점을 가지고, 기껏해야 근력 3 내지 4등급의 회복을 위해 환자에게 큰 부담을 주는, 결과가 확실하지도 않은 수술을 하는 것보다 복잡한 해부학적 구조 및 이에 따른 많은 변종을 가진 상완신경총 손상 환자에게 일단 회복이 되면 더 많은 기능 회복을 줄 수 있는 보존적 요법을 시행하며 자연 회복을 기다리는 것이 났다고 생각한다. 그러므로 저자들은 자연 회복이 수상 후 평균 7.8개월에 시작됨으로 자연 회복을 기대하며 1년간 기다려 본 후 1년이 경과하여도 자연회복이 되지 않는 경우에서 수술적 치료를 시행할 것을 제안한다.

• Archives of Reconstructive Microsurgery
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• 제5권1호
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• pp.24-34
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• 1996

There are many kinds of free flaps for management of extensive soft tissue defect of extremities in orthopaedic field. Free vascularized scapular flap is one of the most useful and relatively easy to application. This flap has been utilize clinically from early eighties by many microsurgical pioneers. Authors performed 102 cases of this flap from 1984 to 1995. We have to consider about the surgical anatomy of the flap, technique of the donor harvesting procedures, vascular varieties and anatomical abnormalities and success rate and the weak points of the procedure. This flap nourished by cutaneous branches from circumflex scapular vessels emerges from the lateral aspect of the subscapular artery 2.5-5cm from its lateral origin passing through the triangular space(bounded by subscapularis, teres minor, teres major, long head of triceps). The terminal cutaneous branch runs posteriorly around the lateral border of the scapular and divided into two major branches, those transeverse horizontally and obliquely to the fascial plane of overlying skin of the scapular body. We can utilize these arteries for scapular and parascapular flap. The vascular pedicle ranged from 5 to 10 cm long depends on the dissection, usually two venae comitantes accompanied circumflex scapular artery and its major branches. The diameter of the circumflex scapular artery is more than 1mm in adult, rare vascular variation. Surgical techniques : The scapular flap can be dissected conveniently with prone or lateral decubitus position, prone position is more easier in my experience. There are two kinds of surgical approaches, most of the surgeon prefer elevation of the flap from its outer border towards its base which known easier and quicker, but I prefer elevation of the flap from its outer border because of the lowering the possibilities of damage to vasculature in the flap itself which runs just underneath the subcutaneous tissue of the flap and provide more quicker elevation of the flap with blunt finger dissection after secure pedicle dissection and confirmed the course from the base of the pedicle. There are minimal donor site morbidity with direct skin closure if the flap size is not so larger than 10cm width. This flap has versatility in the design of the flap shape and size, if we need more longer and larger one, we can use parascapular flap or both. Even more, the flap can be used with latissimus dorsi musculocutaneous flap and serratus anterior flap which have common vascular pedicle from subscapular artery, some instance can combined with osteocutaneous flap if we include the lateral border of the scapular bone or parts of the ribs with serratus anterior. The most important shortcoming of the scapular free flap is non sensating, there are no reasonable sensory nerves to the flap to anastomose with recipient site nerve. Results : Among our 102 cases, overall success rate was 89%, most of the causes of the failure was recipient site vascular problems such as damaged recipient arterial conditions, and there were two cases of vascular anomalies in our series. Patients ages from 3 years old to 62 years old. Six cases of combined flap with latissimus dorsi, 4 cases of osteocutaneous flap for bone reconstruction, 62 parascapular flap was performed - we prefer parascapular flap to scapular. Statistical analysis of the size of the flap has less meaningful because of the flap has great versatility in size. In the length of the pedicle depends on the recipient site condition, we can adjust the pedicle length. The longest vascular pedicle was 14 cm in length from the axillary artery to the enter point cutaneous tissue. In conclusion, scapular free flap is one of the most useful modalities to manage the large intractable soft tissue defect. It has almost constant vascular pedicle with rare anatomical variation, easy to dissect great versatility in size and shape, low donor morbidity, thin and hairless skin.

• 대한후두음성언어의학회지
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• 제10권2호
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• pp.164-169
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• 1999

본 교실에서 시행했던 후두미세수술 1900례중에서 술후 성대낭종으로 확진된 83례를 대상으로 다음과 같은 결과를 얻었다. 1) 전체 후두미세수술 1900례 중 성대낭종이 차지하는 비율은 83례로 4.4%였다. 2) 성대낭종 83례중 유표피낭종은 27례로 32.5%. 저류낭종은 56례로 67.5%를 차지하였다. 3) 성별분포는 83례의 성대낭종중 여성이 55례(66.3%). 남성이 28례 (33.7%)로 여성에서 호발하였고 저류 낭종에서는 남녀비가 17 : 39. 유표피낭종에서는 11 : 16으로 나타났다. 4) 이학적검사 소견으로서 유표피낭종은 보다 진단이 용이하여 술전 이학적 검사상 63%에서 낭종을 의심할 수 있었으나 저류낭종은 성대 폴립이나 결절 등으로 오인되는 경우가 많았고 술전 진단과 술후 진단이 일치하는 경우는 34%에 지나지 않았다. 5) 병리 조직학적 검사상 유표피낭종은 중층 평편상피로 구성된 막을 가지고 있고 내부는 대개 PAS 음성인 케라틴과 콜레스테롤양(cholesterol-like)물질을 포함하고 있고 저류낭종은 원주 또는 입방세포로 구성되어있는 막을 가지고 있으며 주로 PAS양성인 점액 분비물을 내부에 포함하고 있다. 6) 애성 발생과 관련된 유발 요인으로는 성대과용후 33례, 상기도감염후 16례로 성대과용과 상기도감염이 주요한 유발 요인으로 나타났고 성대낭종의 발생에 수다스러움(talkativeness)이 관련성 있게 나타났고 저류낭종에서 관련성이 더욱 높게 나타났다. 7) 발병부위는 대부분에서 막성대유리연의 중간부 및 전방부 1/3에 발생하였고 수술결과는 저류낭종 50례 중 12례에서만 낭종의 파열없이 완전제거가 가능하였으며 유표피낭종은 24례 중 16례에서 낭종의 파열없이 완전제거가 이루어져 저류낭종이 유표피낭종에 비해 파열없이 완전제거가 매우 어려움을 알 수 있었다. 8) 수술전후의 음성만족도는 전체적으로 59%를 나타내어 성대폴립에서의 만족도와의 유사한 결과를 보였다.m)은 각각 0.60, 0.44, 0.40%로 시험초기와 비슷한 수준이었다.의성있게 최대발성지속시간은 감소하고, 평균호기류율은 증가하였으며, 발성기류량과 성문하압은 여자환자에서만 의미 있게 각각 감소하거나 증가하였다. 이상의 결과는 정상인과 성대용종 환자에 있어서 객관적인 공기역학적 검사결과를 보여주며 이는 성대용종 환자의 음성이상에 대한 상태판정이나 치료 후 효과 판정에 기본자료로 이용할 수 있을 것으로 생각된다.야 할 것으로 생각된다. 발생과 피해정도를 예측하여 벼멸구 방제에 중요한 자료로 활용될 수 있을 것으로 생각한다.5) 실험 3에서는 zygote의 VS1 에 노출시간에 따른 생존율을 조사한 결과 융해후 2-cell (91.6, 88.5 및 88.9%) 및 배반포기 (83.3, 74.3 및 69.4%) 까지 배발달율은 1,2 및 3분간의 노출시간에 따른 유의적인 차이를 보이지 않았다. 또한 융해후 노출시간에 따른 할구수에서도 유의적인 차이를 보이지 않았다 (36.4$\pm$4.76, 32.4$\pm$4.67 및 27.6$\pm$4.52). 이상의 결과에서 OPP vitrification 방법은 EFS 또는 EDS 동결보존액에 따른 유의적인 차이 없이 이용될 수 있는 것으로 판단된다. 배발달단계에 따른 생존율은 zygote 의 초기배는 2, 4, 8, 상실배 및 배반포기보다 유의적으로 저조한 생존율을 보였다. Zygote의 VS1에 노출시간에 따른 생존율도 1 분간의 노풀시간에서 높은 배발달율을 보였다. OPP vitrification 동결보존방법으로 생쥐수정란의 동결보존에 유용하게 이용가능한 것으로 판단된다.l the training process, the subject, and area of research, can be pointed out one of the flimsy in our researches of science education.

• Maxillofacial Plastic and Reconstructive Surgery
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• 제33권5호
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• pp.375-384
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• 2011

Purpose: The advent of microsurgical technique and instruments, particularly in the field of perforator flap and supermicrosurgery, which have expanded the scope of microsurgery. However, supermicroanastomosis without any compression, tension, or distortions must be achieved to reach successful outcomes. Small-caliber vessels, such as those with an internal diameter less than 0.2 mm, are susceptible to inadvertent twisting of the anastomosis. In this study, using the superficial inferior epigastric artery (SIEA)-based flap model in Sprague-Dawley (SD) rats, we evaluated the acceptable limits of twisting effects on supermicroanastomotic sites. Methods: A total of 20 supermicroanastomoses were performed using the SIEA-based flap model in 10 male SD rats, 10-weeks-of-age, weighing 300~350 g. Rats were divided into five groups of two with four flaps as follows: 1) sham, 2) control group with end to end SIEA arterial supermicroanastomosis, 3) experimental I (EA1) with $90^{\circ}$ twisting, 4) experimental II (EA2) with $180^{\circ}$ twisting, and 5) experimental III (EA3) with $270^{\circ}$ twisting of the supermicroanastomosis. Each SIEA was anastomosed using six 11-0 $Ethilon^{(R)}$ (Ethicon Inc. Co., NJ, USA) stitches except in the sham group where the SIEA was only clamped with Supermicro vascular $clamps^{(R)}$ (S&T, Neuhausen, Switzerland) for 20 minutes. Results: The anastomosed arterial patency showed no remarkable changes according to doppler waveforms measured with a Smardop 45 Doppler System (Hadeco Inc., Kawasaki, Japan). The pulsatility index (PI) was increased at postoperative day 10 in the EA2 and EA3 groups, and the resistance index (RI) showed no statistically significant difference between preoperative and postoperative values at 10 days. Histologic specimens from the EA3 group showed increased tunica media necrosis, convolution of the internal elastic lamina, densely packed platelets, fibrin, and erythrocytes. Flap viability and anastomosed vessel patency were not significantly affected by the degree of arterial twisting in this study, other than in the EA3 group where minor effects on arterial patency of the microanastomoses were encountered. Conclusion: It appears that minor twisting on small caliber arteries, used in supermicroanastomoses, can be tolerated. However, twisting should be avoided as much as possible, and more than $180^{\circ}$ twisting must be prevented in clinical practice.