• 대한치과보철학회:학술대회논문집
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• 대한치과보철학회 2001년도 추계학술대회
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• pp.70-70
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• 2001

• 대한치과교정학회지
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• 제49권4호
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• pp.235-245
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• 2019

Objective: This study examined bone microstructure restoration after rapid maxillary expansion (RME) with and without corticotomy over multiple retention periods. Methods: Eighteen male Dorper sheep were randomly distributed into three groups (n = 6 each group): group 1, RME with corticotomy on the buccal and palatal sides; group 2, conventional RME treatment; and group 3, no treatment. Post-RME, trabecular bone microstructure and new bone formation were evaluated by using microcomputed tomography (microCT) and histomorphometry after a 4- or 12-week retention period. Intergroup differences in bone quality and bone remodeling were analyzed by using two-way analysis of variance with Bonferroni post-hoc test. Results: The bone volume fraction (bone volume [BV]/total volume [TV]) values relative to the control in groups 1 and 2 were 54.40% to 69.88% after the 4-week retention period and returned to approximately 80% after the 12-week retention period. The pooled BV/TV values of the banded teeth in groups 1 and 2 were significantly lower than those of the control after the 4-week retention period (p < 0.05). However, after the 12-week retention period, the pooled BV/TV values in group 2 were significantly lower than those in groups 1 and 3 (p < 0.05). Histomorphological analysis showed that the new bone formation area in group 1 was approximately two to three times of those in group 2 and control. Conclusions: Corticotomy significantly enhanced the restoration of bone quality after the retention periods for banded teeth. This benefit might result from the increased new bone formation after corticotomy.

• 한국정밀공학회지
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• 제23권2호
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• pp.154-163
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• 2006

Tooth morphology is the most important scientific aspect of dental medicine in regards to the treatment and study of teeth attrition relating to the absence of teeth due to dental caries or the occlusion of teeth due to external force. Most of the studies have focused on the external morphology in cutting teeth regardless of sex and age. However, the importance of internal morphology in the treatment of damaged teeth has been increased. Therefore, this study established the measurement criteria for the morphology of the mandibular first premolar which had never been presented, in order to investigate the external and internal morphologies of mandibular first premolars, and introduced a non-destructive method such as a microcomputed tomogrphy. Mandibular first premolars in superlative state were taken from molars of middle aged males and females and used as specimens for this study. Criteria relating to the internal and external morphology measurements were established to quantify the length of the teeth in identical state. Two dimensional image data for the selected mandibular first premolar were obtained by taking the image of each O.022mm section, which is perpendicular to the vertical direction using the microcomputed tomography. The Vworks program was applied to measure the length of each morphological part according to the set measurement criteria. These measured data were compared with the data presented by G. V. Black and the internal and external morphologies of the teeth of middle aged Koreans were also compared according to gender. In addition, the methodology for measurement of the mandibular first premolar was presented and according to this, the standardized mandibular first premolars of middle aged Korean males and females were made by using a rapid prototyping system.

• 대한치과보존학회:학술대회논문집
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• 대한치과보존학회 2003년도 제120회 추계학술대회 제 5차 한ㆍ일 치과보존학회 공동학술대회
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• pp.577-577
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• 2003

Microcomputed tomography (MCT) made it possible to investigate the morphology of root canals more accurate. The aim of this study was to compare the effects of four root canal shaping methods, the profile system, the ProTaper system, a combination of these, and stainless steel K-files, in the shaping of the mesial root canals of extracted human mandibular first molars, three-dimensionally using MCT. Eight extracted mandibular first molars were scannde using MTC before and after the root cannals were instrumented. Two specimens were prepared using the Profile system and another two specimens were prepared using MCT before and after the root cannals were instrumented. Two specimens were prepared using the Profile system and another two specimens were prepared using the ProTaper system according to manufactures recommendation.(omitted)

• 비파괴검사학회지
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• 제25권4호
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• pp.254-261
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• 2005

지금까지 한국인의 치아 통계는 매우 부족한 상태이고, 대부분 치아형태의 정보를 얻기 위해 방사선학적 방법을 이용하거나, 치아를 절단하는 등의 방법으로 연구를 해왔다. 이와 같은 방법은 오랜 시험 기간을 필요로 하고 정밀도가 낮고 파괴적인 방법을 주로 이용한 것이므로, 이제는 한국인의 표준 치아에 대한 정밀한 데이터를 얻기 위해 새로운 비파괴적인 시험이 필요하다. 이를 위하여 각각의 하악 제1소구치를 미세단층촬영기(Micro-CT, SkyScan, Belgium)를 이용하여 $21.31{\mu}m$의 해상도로 교합면에 대한 수평면으로 0.022mm 로 Scan을 하였다. 이를 통하여 내 외부 형태학적 중요부위를 측정하였으며, 영구 치아의 평균 치수표로 사용했었던 G. V. Black(1836-1915)에 의해 제시된 수치와 비교하였다.

• Journal of Korean Neurosurgical Society
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• 제60권3호
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• pp.348-354
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• 2017

Objective : To identify and investigate differences in spinal fusion between the normal and osteopenic spine in a rat model. Methods : Female Sprague Dawley rats underwent either an ovariectomy (OVX) or sham operation and were randomized into two groups: non-OVX group and OVX group. Eight weeks after OVX, unilateral lumbar spinal fusion was performed using autologous iliac bone. Bone density (BD) was measured 2 days and 8 weeks after fusion surgery. Microcomputed tomography was used to evaluate the process of bone fusion every two weeks for 8 weeks after fusion surgery. The fusion rate, fusion process, and bone volume parameters of fusion bed were compared between the two groups. Results : BD was significantly higher in the non-OVX group than in the OVX group 2 days and 8 weeks after fusion surgery. The fusion rate in the non-OVX group was higher than that in the OVX group 8 weeks after surgery (p=0.044). The bony connection of bone fragments with transverse processes and bone formation between transverse processes in non-OVX group were significantly superior to those of OVX group from 6 weeks after fusion surgery. The compactness and bone maturation of fusion bed in non-OVX were prominent compared with the non-OVX group. Conclusion : The fusion rate in OVX group was inferior to non-OVX group at late stage after fusion surgery. Bone maturation of fusion bed in the OVX group was inferior compared with the non-OVX group. Fusion enhancement strategies at early stage may be needed to patients with osteoporosis who need spine fusion surgery.

• Journal of Biomedical and Translational Research
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• 제19권4호
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• pp.73-78
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• 2018

Osteoporosis is a major worldwide public health problem that poses a great economic burden to society. Puerariae Radix, the dried root of Pueraria lobata (Wild.) Ohwi, has been widely used in Asia. This study investigated the effects of Puerariae Radix (PR) on bone loss in ovariectomized (OVX) mice. C3H/HeN mice (10 weeks old) were divided into sham and OVX groups. The OVX mice were treated with vehicle, $17{\beta}-estradiol$ ($E_2$), PR (oral administration, 250 mg/kg/day) or PR (intraperitoneal administration, 50 mg/kg/every other day) for 6 weeks. Grip strength, uterus weight, serum alkaline phosphatase (ALP), estradiol concentration and osteoclast surface levels were measured. Tibiae were analyzed using microcomputed tomography. There were no significant differences in the degree of grip strength, body weight and uterine weight between OVX group and PR-treated group. As compared with the OVX group, the serum estradiol levels were significantly increased in the PR-treated group. PR (i.p.) significantly preserved trabecular bone volume, trabecular bone number, structure model index and bone mineral density of proximal tibiae metaphysic. The administration of PR lowered serum ALP and osteoclast surface levels in OVX mice, suggesting that PR can reduce the bone turnover rate in mice. The results indicate that the supply of PR can prevent OVX-induced bone loss in mice.

• 대한소아치과학회지
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• 제49권3호
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• pp.348-356
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• 2022

과잉치는 치판의 과도한 성장과 분화에 의해서 발생된다. 이로 인해 이소맹출, 맹출지연, 인접치의 치근 흡수, 그리고 치간이개 등의 문제가 발생할 수 있다. 영유아기에서의 과잉치는 드물며 국내에서는 거의 보고되지 않았다. 이 증례에서는 3개의 매복된 과잉치가 있는 생후 2일된 신생아에 대해 보고하고 있으며, 환자는 21개월간 추적 관찰되었다. 유치열기에 맹출된 하나의 과잉치는 14개월이 되었을 때 중등도 진정 하에 발치되었다. 발치된 과잉치에 대해 micro-computed tomography (CT) 분석을 진행하여 치근단 부위의 미세한 형태 이상을 확인하였다. 과잉치 발치 후 치간이개는 감소하였고 구강위생도 개선되었다. 조기 진단 및 치료를 통해 과잉치로 인한 합병증을 예방할 수 있다.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제42권2호
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• pp.90-98
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• 2016

Objectives: The aim of this study was to compare the osteogenic effects of demineralized dentin matrix (DDM) combined with recombinant human bone morphogenetic protein-2 (rhBMP-2) in rabbit calvarial defects with DDM and anorganic bovine bone (ABB) combined with rhBMP-2. Materials and Methods: Four round defects with 8-mm diameters were created in each rabbit calvaria. Each defect was treated with one of the following: 1) DDM, 2) ABB/rhBMP-2, or 3) DDM/rhBMP-2. The rhBMP-2 was combined with DDM and ABB according to a stepwise dry and dip lyophilizing protocol. Histological and microcomputed tomography (${\mu}CT$) analyses were performed to measure the amount of bone formation and bone volume after 2- and 8-week healing intervals. Results: Upon histological observation at two weeks, the DDM and ABB/rhBMP-2 groups showed osteoconductive bone formation, while the DDM/rhBMP-2 group showed osteoconductive and osteoinductive bone formation. New bone formation was higher in DDM/rhBMP-2, DDM and ABB decreasing order. The amounts of bone formation were very similar at two weeks; however, at eight weeks, the DDM/rhBMP-2 group showed a twofold greater amount of bone formation compared to the DDM and ABB/rhBMP-2 groups. The ${\mu}CT$ analysis showed markedly increased bone volume in the DDM/rhBMP-2 group at eight weeks compared with that of the DDM group. Notably, there was a slight decrease in bone volume in the ABB/rhBMP-2 group at eight weeks. There were no significant differences among the DDM, ABB/rhBMP-2, and DDM/rhBMP-2 groups at two or eight weeks. Conclusion: Within the limitations of this study, DDM appears to be a suitable carrier for rhBMP-2 in orthotopic sites.

• 대한소아치과학회지
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• 제30권3호
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• pp.406-414
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• 2003

건전 치질을 최대한 보존하고자 하는 노력의 일환으로 화학 기계적 우식 제거법이 개발되었다. 치아의 손상 없이 3차원 자료를 얻을 수 있는 미세 전산화단층촬영과 V works program을 사용하여 이 방법의 우식 제거 효능을 평가하였다. 1군은 건전 상아질, 우식 상아질, 화학 기계적 방법을 사용하여 형성된 와동벽의 밀도값을 구하여 분석하였다. 2군은 건전 상아질, 고속 회전 절삭 기구를 사용하여 형성된 와동벽, 여기에 추가로 화학 기계적 우식 제거 용액을 적용한 후의 와동벽의 밀도를 구하여 분석하였다. 결과는 다음과 같다. 1. $Carisolv^{TM}$로 우식을 제거한 후의 와동벽 상아질의 밀도값은 정상 상아질 밀도값의 81.8%이었다(p < 0.001). 2. Bur를 사용하여 우식을 제거한 경우에는 와동벽과 정상 상아질 밀도값에 통계적으로 유의한 차이가 없었다(p = 0.234).