• Title/Summary/Keyword: Micro-water-nozzle

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Experiments of Micro Jet Injection for Bio-Medical Application (바이오 분야 적용을 위한 마이크로 젯 인젝션 실험)

  • Ham, Young-Bog;An, Byeung-Cheol;Trimzi, Mojiz Abbas;Kim, Jong-Dae;Lee, Gi-Tae;park, Jung-Ho;Yun, So-Nam
    • Transactions of the Korean Society of Mechanical Engineers B
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    • v.40 no.10
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    • pp.681-687
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    • 2016
  • It is essential for micro jet injectors in the biomedical sector to operate under high pressure. High pressure injection, however, is accompanied by high volumes. On/Off valves that can be operated at high speeds have been used to address this problem. In this research, piezoelectric actuators which have a response frequency of the order of hundreds of kilohertz were used as the On/Off valve and experiments were applied. Researchers developed a controller to precisely manipulate the piezoelectric valve with various waveforms. They also fabricated five types of nozzles to consider the effect of nozzle type on injection. This allowed researchers to manipulate and confirm factors that can affect the injection volume and force. Results of this experiment have shown how to decrease the injection volume and increase the injection force. and it is predicted that the optimized injection volume and force value can be determined depending on the skin type.

Comparison of the Gel Formation Ability and Stability of Encapsulated Microbial Inoculant Using Extractable Alginate from Sea Tangle (다시마 추출 Alginate를 이용한 미생물 캡슐화제의 겔 형성능 및 생균력 비교)

  • Choi, So-Young;Yoon, Min-Ho;Whang, Kyung-Sook
    • Applied Biological Chemistry
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    • v.49 no.3
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    • pp.170-174
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    • 2006
  • For the purpose of developing a high quality agricultural microbial inoculant, methods and materials for improving encapsulation were investigated. Preparation of capsule was conducted by improving extrusion system with micro-nozzle and peristaltic pump. The sodium alginate was selected because of its cheapness, stability of cells, and gel formation ability. The yields, physical properties and gel formation abilities of extractable alginate from sea tangle were investigated by hot water extractable and alkali soluble methods. The extraction yields of hot water extractable alginate (HWEA) and alkali soluble alginate (ASA) from sea tangle were 8 and 20%, respectively. The HWEA was almost not viscous even in 1.5% of the sample solution, whereas the ASA was very highly viscous in above 3% sample solution. The gel formation ability of each samples varied from 1.5% to 5% and the ASA showed a good gel formation ability at 3% solution as commercial alginate (CA). The soil microbial inoculant, Bacillus thuringiensis, Bacillus subtilis, Lactobacillus plantarum and Geotrichum candidum encapsulated sodium alginate with starch and zeolite for stabilizer. The survivability of encapsulated soil microbial inoculant using alginate without stabilizer appeared to be 66, 52, 70 and 50%, respectively. Inclusion of starch and zeolite with alginate bead increased viabilities in Bacillus sp. and Geotrichum candidum by 81-83% and 89%, respectively.