• Title/Summary/Keyword: Micro-imaging

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Design of Two-way Image Acquisition System for 25\μm Tool Alignment in the Micro Hole Punching (25\μm 홀 펀칭 공구 정렬을 위한 광학 시스템 설계)

  • 주병윤;임성한;오수익
    • Transactions of Materials Processing
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    • v.13 no.3
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    • pp.190-204
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    • 2004
  • The objective of this study is to develop a highly accurate micro tool alignment system applicable to the micro machining technology. In a specific application such as micro hole punching, radial clearance between micro tools is order of a few micron. Under this micron scale tool clearance, accuracy of tool alignment is very important for ensuring hole quality. In the present study, a two-way image acquisition system was developed, which can produce overlapped image of both micro tools that face each other, and applied to the tool alignment in the micro punching. Also, to meet alignment accuracy of tools within $1\mu\textrm{m}$, the cross correlation image processing algorithm was employed. With this system, $25\mu\textrm{m}$ punching tools with $1\mu\textrm{m}$ radial clearance could be accurately aligned.

Terahertz Pulse Imaging of Micro-metastatic Lymph Nodes in Early-stage Cervical Cancer Patients

  • Jung, Eun-A;Lim, Mee-Hyun;Moon, Ki-Won;Do, Young-Woong;Lee, Soon-Sung;Han, Hae-Wook;Choi, Hyuck-Jae;Cho, Kyoung-Sik;Kim, Kyu-Rae
    • Journal of the Optical Society of Korea
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    • v.15 no.2
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    • pp.155-160
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    • 2011
  • Lymph node metastasis is an important prognostic factor in cervical cancer patients. We report THz imaging for detecting micro-metastatic foci in the lymph nodes of early-stage uterine cervical cancer patients. Five paraffin-embedded metastatic lymph nodes from two cervical cancer patients were imaged using a THz time-domain spectroscopy system in the reflection mode. The size and shape of the tumor regions were compared with those from histopathologic examinations. The metastatic portions of lymph nodes as small as 3 mm were well delineated by THz imaging. The reflected peak amplitudes were lower in metastatic portions than in the normal portions of lymph nodes, and the difference in their peak-to-peak amplitudes was ~5%.

A Pseudo-Self-Imaging Phenomenon in Multimode Waveguides

  • Hong Jong-Kyun;Lee Sang-Sun;Song Seok-Ho
    • Journal of the Optical Society of Korea
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    • v.10 no.2
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    • pp.81-85
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    • 2006
  • This study introduces an undefined self-imaging phenomenon, called here the pseudo-self-imaging phenomenon. The relative phases of the guided modes were used to discover how the pseudo-self-images are formed. The pseudo-self-image was found and measured experimentally. The experimental results showed that both the pseudo-self-image and the 0-dB self-image have similar intensity values and have opposite positions in the lateral direction.

Relationship Analysis of Break-up Mode and Heat Transfer of Micro-Speaker Diaphragm (마이크로 스피커 진동판에 대한 분할진동 모드와 열전달의 관계 분석)

  • Kim, Hyun-Kab;Kim, Hie-Sik
    • Transactions of the Korean Society of Mechanical Engineers A
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    • v.41 no.4
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    • pp.333-336
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    • 2017
  • A speaker diaphragm generates a divided vibration. The influence of the break-up mode is sufficient to cause a shape change in the diaphragm. In this paper, is widely used in ultra-thin multi-media devices, including smart phones is the advance guard of the IT sector, the micro-speakers and its target. Micro-speakers are different from general speakers. The plate has structural form and space constraints. In particular, they utilize a closed-type drive space. It is difficult to provide cooling for the auxiliary suspension structure because of the heat generated in the moving coil. The present study considered the relationship between the break-up mode and the heat transfer of the diaphragm. An experiment was conducted in two stages to compare the embodiment of the break-up mode and heat transfer in a certain frequency range. The changes in the heat were determined through measurements and thermal imaging of the break-up mode. The break-up mode tendency of the diaphragm could be rapidly predicted based on the imaging results using the thermal imaging camera. This will help in the optimal design of micro-speakers.

Optimal Flip Angle for T2-Weighted Effect in Micro 4.7T MRI SE Sequence (마이크로 4.7T MRI SE Sequence에서 T2강조효과를 위한 최적의 Flip Angle)

  • Lee, Sang-Ho
    • Journal of radiological science and technology
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    • v.42 no.2
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    • pp.113-117
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    • 2019
  • The purpose of this study was to investigate the FA value which can produce the best T2-weighted images by measuring the signal intensity and noise according to the FA value change in the brain image and the abdominal image of the mouse using micro-MRI. Brain imaging and abdominal imaging of BALB / C mice weighing 20g were performed using 4.7T (Bruker BioSpin MRI GmbH) micro-MRI equipment, Turbo RARE-T2 (spin echo-T2) images were scanned at TR 3500 msec and TE 36 msec. The changes of the FA values were $60^{\circ}$, $80^{\circ}$, $100^{\circ}$, $120^{\circ}$, $140^{\circ}$, $160^{\circ}$ and $180^{\circ}$. We measured signal intensity according to FA values of ventricle and thalamus in brain imaging, The signal intensity of kidney and muscle around the kidney was measured in abdominal images. To obtain SNR and CNR, we measured the background signals of two different parts, not the tissue. In the brain (thalamus) image, the signal intensity of FA $100^{\circ}$ was 7,433 and SNR (6.49) was the highest. In the abdominal (kidney) image, the signal intensity was highest at 16,523 when FA was $120^{\circ}$, and the highest SNR was 8.54 when FA was $140^{\circ}$. The CNR value of the brain image was 1.38 at FA $60^{\circ}$ and gradually increased to 8.29 at FA $180^{\circ}$. The CNR value of the muscle adjacent to the kidney gradually increased from 2.36 when the FA value was $60^{\circ}$ and the highest value was 4,57 at the FA value $180^{\circ}$.

Micro- PIV Measurements of Microchannel Flows and Related Problems (마이크로 채널 내부 유동의 Micro-PIV측정과 제반 문제점)

  • Lee Sang-Joon;Kim Guk-bae
    • 한국가시화정보학회:학술대회논문집
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    • 2002.04a
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    • pp.79-84
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    • 2002
  • Most microfluidic devices such as heat sinks for cooling micro-chips, DNA chip, Lab-On-Chip, and micro pumps etc. have microchannels of various size. Therefore, the design of practical microfluidics demands detail information on flow structure inside the microchannels. However, detail velocity field measurements are rare and difficult to carry out. In addition, as the microfluidics expands, accurate understanding of microscale transport phenomena becomes very important. In this research, micro-PIV system was employed to measure the velocity fields of flow inside a micro-channel. We carried out PIV measurements for several microchannels with varying channels width, inlet and outlet shape, filters, CCD camera and ICCD camera, etc. For effective composition of micro-PIV system, first of all, it is essential to understand optics related with micro-imaging of particles and the particle dynamics encountered in micro-scale channel flows. In addition, it is necessary to find the optimal condition for given experimental environment and? micro-scale flow to be investigated. The problems encountered in measuring velocity field of micro-channel flows are discussed in this paper.

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Pre-evaluation of Non-alcoholic Fatty Liver Disease Model Using Micro-MRI: For Big Data Application (비알콜성 간 질환 동물모델 영상 빅 데이터 구축을 위한 영상데이터 수집 및 사전평가)

  • Lee, Gi-Taek;Jun, Hong Young;Kim, Tae-Hoon;Jang, Mi Yeon;Kim, Dae Won;Yoon, Kwon-Ha
    • Proceedings of the Korea Information Processing Society Conference
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    • 2017.04a
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    • pp.982-983
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    • 2017
  • 본 연구는 최근 문제가 되고 있는 비알콜성 간 질환에 대한 빅 데이터의 사전 데이터를 만들기 위해 마우스에서 고지방 식이와 Streptozotocin ((STZ)로 모델을 제작하였고, 당뇨와 비만 정도를 측정하여 질환발생 정도를 확인하였다. 또한, MR영상의 지속적인 촬용으로 질환발생과정에 대해 3D분석 소프트웨어로 평가되었다.

Micro-CT System for Small Animal Imaging (소동물영상을 위한 마이크로 컴퓨터단층촬영장치)

  • Nam, Ki-Yong;Kim, Kyong-Woo;Kim, Jae-Hee;Son, Hyun-Hwa;Ryu, Jeong-Hyun;Kang, Seoung-Hoon;Chon, Kwon-Su;Park, Seong-Hoon;Yoon, Kwon-Ha
    • Progress in Medical Physics
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    • v.19 no.2
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    • pp.102-112
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    • 2008
  • We developed a high-resolution micro-CT system based on rotational gantry and flat-panel detector for live mouse imaging. This system is composed primarily of an x-ray source with micro-focal spot size, a CMOS (complementary metal oxide semiconductor) flat panel detector coupled with Csl (TI) (thallium-doped cesium iodide) scintillator, a linearly moving couch, a rotational gantry coupled with positioning encoder, and a parallel processing system for image data. This system was designed to be of the gantry-rotation type which has several advantages in obtaining CT images of live mice, namely, the relative ease of minimizing the motion artifact of the mice and the capability of administering respiratory anesthesia during scanning. We evaluated the spatial resolution, image contrast, and uniformity of the CT system using CT phantoms. As the results, the spatial resolution of the system was approximately the 11.3 cycles/mm at 10% of the MTF curve, and the radiation dose to the mice was 81.5 mGy. The minimal resolving contrast was found to be less than 46 CT numbers on low-contrast phantom imaging test. We found that the image non-uniformity was approximately 70 CT numbers at a voxel size of ${\sim}55{\times}55{\times}X100\;{\mu}^3$. We present the image test results of the skull and lung, and body of the live mice.

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