• 한국정밀공학회지
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• 제21권10호
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• pp.188-195
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• 2004

In this paper, we fabricated fluidic devices like micro-channel, pump, mixer and particular gas separator with the technology of stereolithouaphy using RP(rapid-prototyping). The fabricated fluidic devices are expected to be applied to develop Lab-on-a chip type liquid analyzer. Stereolithography technology seems effective for fabricating MEMS(Micro Electro Mechanical System) with complicated structure because it makes three dimensional fabrication possible but, exclusive devices are needed to be developed fur fabricating even more microscopic MEMS structure.

• 한국반도체및디스플레이장비학회:학술대회논문집
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• 한국반도체및디스플레이장비학회 2004년도 International Symposium
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• pp.1-15
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• 2004

o Various microfluidic components including mixromixers and micropumps have been developed for disposable biochip applications. o Single cell capturing, positioning and nanoliter drug injection chip has been demostrated. o Multi-channel, two-dimensional micro-well array has been fabricated and cell capturing and specific reagent injection have been performed.

• Design & Manufacturing
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• 제2권1호
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• pp.45-50
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• 2008

Micro channel is to fabricate desired pattern on the polymer substrate by pressing the patterned mold against the substrate which is heated above the glass transition temperature, and it is a high throughput fabrication method for bio chip, optical microstructure, etc. due to the simultaneous large area patterning. However, the bad pattern fidelity in large area patterning is one of the obstacles to applying the hot embossing technology for mass production. In the present study, stamper of cross channel with width $100{\mu}m$ and height $50{\mu}m$ was manufactured using UV-LiGA process. Micro channel was manufactured using stamper manufactured in this study. Also replicability appliance was evaluated for micro channel and factors affected replicability were investigated using Taguchi method.

• 한국정밀공학회:학술대회논문집
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• 한국정밀공학회 2010년도 춘계학술대회 논문집
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• pp.637-638
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• 2010

• 한국가시화정보학회:학술대회논문집
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• 한국가시화정보학회 2004년도 Proceedings of 2004 Korea-Japan Joint Seminar on Particle Image Velocimetry
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• pp.65-74
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• 2004

Measurement of concentration distributions of suspended particles in a micro-channel is out of the most crucial necessities in the area of Lab-on-a-chip to be used for various bio-chemical applications. One most feasible way to measure the concentration field in the micro-channel is using micro-LIF(Laser Induced Fluorescence) method. However, an accurate concentration field at a given cross plane in a micro-channel has not been successfully achieved so far due to various limitations in the light illumination and fluorescence signal detection. The present study demonstrates a novel method to provide an ultra thin laser sheet beam having five(5) microns thickness by use of a micro focus laser line generator. The laser sheet beam illuminates an exact plane of concentration measurement field to increase the signal to noise ratio and considerably reduce the depth uncertainty. Nile Blue A was used as fluorescent dye for the present LIF measurement. The enhancement of the fluorescent intensity signals was performed by a solvent mixture of water $(95\%)$ and ethanol (EtOH)/methanol (MeOH) $(5\%)$ mixture. To reduce the rms errors resulted from the CCD electronic noise and other sources, an expansion of grid size was attempted from $1\times1\;to\;3\times3\;or\;5\times5$ pixel data windows and the pertinent signal-to-noise level has been noticeably increased accordingly.

• 한국전기전자재료학회:학술대회논문집
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• 한국전기전자재료학회 2006년도 영호남 합동 학술대회 및 춘계학술대회 논문집 센서 박막 기술교육
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• pp.71-73
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• 2006

This research aims to develop a multiple channel electrochemical DNA chip using micro- fabrication technology. At first, we fabricated a high integrated type DNA chip array by lithography technology. Several probe DNAs consisting of thiol group at their 5-end were immobilized on the gold electrodes. Then target DNAs were hybridized by an electrical force. Redox peak of cyclic-voltammogram showed a difference between target DNA and mismatched DNA in the anodic peak current. Therefore. it is able to detect a various genes electrochemically after immobilization of a various probe DNA and hybridization of label-free DNA on the electrodes simultaneously. It suggested that this DNA chip could recognize the sequence specific genes.

• ESCO지
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• 통권13호
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• pp.50-55
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• 2001

최근의 계속된 칩(Chip)기술의 발전으로 전자부품의 고성능화가 가능해 졌지만, 그에 따라서 부수적으로 전자제품으로부터 발생되는 열로 인한 많은 열적인 문제도 야기되었다. 칩자체의 초소형화와 고성능화는 전자, 통신, 항공 우주, 각종 에너지 시스템들의 소형화가 더욱 가능해졌고, 또한 이러한 시스템들의 열적인 문제를 해결할 장치들도 초소형화하는 제품들이 필요하게 되었다. 따라서 본 기술에서는 초소형 전자기기시스템(Micro-Electro Mechanical System) 기술의 발전에 따라 가공이 가능하게 된 초소형 열교환기(Micro Heat Exhanger)에 관한 기술을 초소형 채널 열교환기(Micro Channel Heat Exchanger), 그리고 초소형 히트파이프 열교환기(Micro Heat Pipe Heat Exchanger)와 같이 세 가지로 분류하여 그 기술의 현재와 앞으로의 전망을 소개하고자 한다.

• 전자공학회논문지B
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• 제31B권10호
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• pp.21-31
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• 1994

This paper describes the multichannel combined R2MFC/DTMF/CCT reciver which provides a signaling service functions for call processing control in digital switching system. Using the TMS320C25 DSP chip, we have implemented multi-function receriver shich processes 8 channels of R2MFC, DTMF, and CCT signals simultaneously. In order to increase the channel multiplicity of the combined receiver. R2MFC and CCT receiver were employed by discrete Fourier transform(DFT) method using Goertzel algorithm, and DTMFreceiver was employ by infinite impulse reponse(IIR) filtering method using 4KHz subsampling technique. The combined receiver has 4 function modes for each channel such as R2MFC, DTMF, CCT, and Idle modes. The function mode of each channel may be selected at any time by single-chip micro-controller(.mu.C). Hence, the number of channels assigned for each function mode can be adjusted dynamically according to the signaling traffic variations. From the experimental test results using the test-bed, it has been proved that the combined receiver statisfies all receiver satisfies all receiver specifications, and provides good channel multiplicity and performance, Therefore, it may give a great improvement than existing receiver in cost, reliability, availability, and serviceability.

• 한국가시화정보학회:학술대회논문집
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• 한국가시화정보학회 2007년도 추계학술대회
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• pp.71-76
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• 2007

Flow visualization of a droplet passing through a straight channel and a diverging channel has been carried out using micro-PIV. Diverging channel is frequently used in lab-on-a-chip and microfluidic devices, where flow pattern inside the droplet passing is quite different from that through a straight channel. In the present study, we visualized the droplet flow in three different regions. The first region is where the droplet has a wide contact area with the channel wall, the second region is characterized with a narrow contact area and the third region is where droplet is detached from the channel wall. Visualization results show that the internal flow inside the droplet passing through the straight channel moves in the opposite direction to the droplet velocity in the near wall exhibiting complex flow patterns. But in the diverging channel the internal flow inside the droplet moves in the same direction as the droplet velocity due to the shear induced by oil phase flow exhibiting rather simple flow pattern.

• 한국정보통신학회논문지
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• 제13권7호
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• pp.1475-1482
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• 2009

본 논문에서는 최적의 Lab-on-a-Chip을 설계하기 위해 나선형 마이크로 채널에서 등속영동 프로틴 분리를 수행하는 컴퓨터 시뮬레이션을 이차원 유한 요소법을 이용하여 개발하였다. 개발한 이차원 ITP 모델은 다섯 가지 요소로 구성되며 Leader로서 염산을, Terminator로서 카르로산, 두 개의 프로틴 중 프로틴 A는 아세트산, 프로틴 B는 벤조산, 그리고 BE(Background Electrolyte)로서 히스티딘을 사용하였다. 컴퓨터 모델은 다섯 가지 구성 요소들에 대한 질량 보존 방정식과 전위에 대한 전하 보존 방정식, 그리고 pH 계산은 전기적 중성 조건식에 기반하고 있다. 제안된 이차원 공간 ITP 모델의 검증을 위해 제안한 모델의 결과와 Bohuslav Gas 그룹에서 개발한 Simu 5의 결과를 비교하였다. 시뮬레이션 결과 일차원 채널에서 두 모델이 매우 유사한 일치를 보임으로 제안한 모델의 정확성을 검증해 주었다. 이차원 프로틴 분리는 Lab-on-a-Chip 설계를 위한 이차원 곡선 채널에서 수행되어 채널 형상이 프로틴 포커싱분포(dispersions)의 변화를 초래함을 알 수 있었다.