• Proceedings of the Korean Society of Precision Engineering Conference
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• 2003.06a
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• pp.589-592
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• 2003

In the machining process of micros shape by using high-precision machining system and micro end-mill, it is important for machining characters of tools to be grasped in order to stably use tools of micro end-mill. In this study. we carried out an analytical experiment of basic machining features by using end-mill tools for the purpose of damage prevention and manufacture of high quality when the tools of micro end-mill are used. This experiment used a micro machining system with high precision and a variety of end-mill tools commercialized from tens to hundreds microns in diameter. To establish an optimal machining condition without tool damage, cutting force was analyzed according to the changes of tool diameter and cutting conditions such as cutting speed. feed rate, depth of cut. And an examination was performed for the shape and surface illumination of machining surface according to the changes of machining conditions. Based on these micro machining conditions, micro square pillar, cylinder shaft. thin wall with high aspect ratio, and micro 3-D structures such as micro gear and fan were manufactured.

• 한국정보디스플레이학회:학술대회논문집
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• 2008.10a
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• pp.1293-1296
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• 2008

As Flat Panel Display become large in format, the data and gate lines turn into longer, parasitic capacitance and resistance increase, and the display signal is delayed. Three dimensional architecture of multiplexing data registration integrated circuit method is used that divides the data line into several blocks and provides the advantages of high accuracy, rapid selection, and reasonable switching speed.

• Journal of Biosystems Engineering
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• v.15 no.2
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• pp.134-142
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• 1990

This study was carried out for the development of greenhouse temperature control system by modifying an APPLE-II microcomputer attached with several interface systems. The interface systems are composed of 12 bit A/D converter, output port, multiplexer, time clock, etc. Under the operation of developed system, the greenhouse temperature was to be manipulated within the setting temperatures assumed to be appropriate for certain plant growth. The temperature control equimpents installed in the greenhouse are one-speed propeller type fan and two-phase electric heater, which are selectively started or stopped according to the control logic programmed in the control system. The results are summarized as follows : 1. The difference between two temperatures measured by the developed system and the self-recording thermometer calibrated with standard thermometer was less than $1^{\circ}C$. 2. When the temperature were measurd by 12 bit A/D converter and both electric heater and ventilation fan were controlled by developed ON/OFF logic, greenhouse temperature showed narrow fluctuation bands of less than $1^{\circ}C$ near the setting temperatures. 3. The temperature acquisition and control system developed in this study is expected to be applicable to environment control system such as greenhouse only by modifying the logic based on long term experimental data. 4. In order to reduce the measurement error and to increase the system control efficiency, it is recommended that continuous study should be carried out in the aspect of eliminating various systematic noises and improving the environmental control logic.

• Journal of the Korean association of regional geographers
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• v.2 no.2
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• pp.197-204
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• 1996

We attempt to classifing method of micro-landform on the alluvial plain, such as natural-levee, backmarsh and alluvial fan, using false color composite of Landsat Thematic Mapper image. The study area is Kumho River Basin on the southeastern part of Korea peninsula. The most effective image for micro-landform classification is the false color composite of band 2, 3 and 4 with blue, green and red filtering. The most favorable time is the middle third of November, because of the density differentiation of green vegetation in most great. In this time the paddy field on the back-marsh is bare by rice harvesting. But on the natural levee the green vegetation, such as vegetables and lower herbs under fruit tree, remain relatively more. On the alluvial fan, the green vegetation condition is medium. For the verification of the micro-landform classification, we employed the field survey and grain size analysis of the deposition of each micro-landform on the sample area. It is clarified that the classification method of micro-landform on the alluvial plain using the Landsat TM image is relatively useful.

• Journal of the Speleological Society of Korea
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• no.68
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• pp.75-98
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• 2005

Korea physiographic province is divided into two provinces which is northern Chugaryung graben zone and southern Chugraryung graben zone. Northern Chugraryung is also divided in to Gema block and Kohan block, and southern Chugraryung dividedinto Han block, Yongnam basin and Honam plain. The above mentioned macro geomorophic units is divided, mainly on the geotectonics. The meso geomorphic units is divided, based upon the regional distribution of topographic characteristic that is plateaus, mountains, mountain range, basins and great plain etc. Micro geomorphic units id into a mountain, a hill, a plain, and a lowland, and then it is formed by selfreliant topographic unit. And micro topographic (fan, peneplain, delta, etc) dealt with a characteristics unit. In this article has a disregarded amallest scale that is included flood plait natural levee, back marsh and oxbow lake etc. Accordingly, it shows macro units are meso units are 5, meso units are 53, micro units are 299. A study method of physiographic provincs prefered to aufsteigende and abstergands methoy. How to organically combine topographic factors can be seen in regional distribution of the peculiar topographic characteristics, for charage teristic of topographic makes a study on the topographic of micro unit such understanding as aufsteigende method. At the same time, since it can be studied systematically from marco unit to micro unit like the absteigende methods, I used both methods. And this establishment of physiographic province based on the scientific method depend on the base map of climate classification. Geology, Soil, Biology. I feel confident that it will be used the basic map for land use map, land classification map, study of geomorphology of Korea. And will be used for study of a topographic standard data.

• Journal of Mushroom
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• v.15 no.1
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• pp.14-20
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• 2017

The oyster mushroom cultivation house typically has multiple layers of growing shelves that cause the disturbance of air circulation inside the mushroom house. Due to this instability in the internal environment, growth distinction occurs according to the area of the growing shelves. It is known that minimal air circulation around the mushroom cap facilitates the metabolism of mushrooms and improves their quality. For the purpose of this study, a CFD analysis FLUENT R16 has been carried out to improve the internal environment uniformity of the oyster mushroom cultivation house. It is found that installing a section of the working passage towards the ceiling is to maintain the internal environment uniformity of the oyster mushroom cultivation house. When all the environment control equipment - including a unit cooler, an inlet fan, an outlet fan, an air circulation fan, and a humidifier - were operated simultaneously, the reported Root Mean Square (RMS) valuation the growing shelves were as follows: velocity 23.86%, temperature 6.08%, and humidity 2.72%. However, when only a unit cooler and an air circulation fan operated, improved RMS values on the growing shelves were reported as follows: velocity 23.54%, temperature 0.51%, and humidity 0.41%. Therefore, in order to maintain the internal environment uniformity of the mushroom cultivation house, it is essential to reduce the overall operating time of the inlet fan, outlet fan, and humidifier, while simultaneously appropriately manage the internal environment by using a unit cooler and an air circulation fan.

• 한국정보디스플레이학회:학술대회논문집
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• 2008.10a
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• pp.1405-1408
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• 2008

Synchronization signal circuit system for low cross-talk stereoscopic display. We proposed the employment of the scanning beams of any adjacent scanning regions gradually scan from upper to down direction of the LED backlight panel.

• 한국정보디스플레이학회:학술대회논문집
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• 2008.10a
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• pp.710-713
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• 2008

LED Scanning Backlight Stereoscopic Display with Shutter Glasses is provided to realize stereoscopic image viewing even in a liquid crystal display. The eye shutter signal is alternately switched from the left eye to the right eye with 120Hz of LCD Vertical synchronization (V-sync).

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.8
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• pp.3471-3476
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• 2014

Background: Aberrant expression of the microRNA-29 family is associated with tumorigenesis and cancer progression. As transport carriers, tumor-derived exosomes are released into the extracellular space and regulate multiple functions of target cells. Thus, we assessed the possibility that exosomes could transport microRNA-29c as a carrier and correlations between microRNA-29c and apoptosis of bladder cancer cells. Materials and Methods: A total of 28 cancer and adjacent tissues were examined by immunohistochemistry to detect BCL-2 and MCL-1 expression. Disease was Ta-T1 in 12 patients, T2-T4 in 16, grade 1 in 8, 2 in 8 and 3 in 12. The expression of microRNA-29c in cancer tissues was detected by quantitative reverse transcriptase PCR (QRT-PCR). An adenovirus containing microRNA-29c was used to infect the BIU-87 human bladder cancer cell line. MicroRNA-29c in exosomes was measured by QRT-PCR. After BIU-87 cells were induced by exosomes-derived microRNA-29c, QRT-PCR was used to detect the level of microRNA-29c. Apoptosis was examined by flow cytometry and BCL-2 and MCL-1 mRNA expressions were assessed by reverse transcription-polymerase chain reaction. Western blotting was used to determine the protein expression of BCL-2 and MCL-1. Results: The expressions of BCL-2 and MCL-1 protein were remarkably increased in bladder carcinoma (p<0.05), but was found mainly in the basal and suprabasal layers in adjacent tissues. The expression of microRNA-29c in cancer tissues was negatively correlated with the BCL-2 and MCL-1. The expression level of microRNA-29c in exosomes and BIU-87 cells from the experiment group was higher than that in control groups (p<0.05). Exosome-derived microRNA-29c induced apoptosis (p<0.01). Although only BCL-2 was reduced at the mRNA level, both BCL-2 and MCL-1 were reduced at the protein level. Conclusions: Human bladder cancer cells infected by microRNA-29c adenovirus can transport microRNA-29c via exosomes. Moreover, exosome-derived microRNA29c induces apoptosis in bladder cancer cells by down-regulating BCL-2 and MCL-1.

• The Korean Journal of Physiology and Pharmacology
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• v.27 no.2
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• pp.131-141
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• 2023

Compelling evidence has demonstrated the critical role of circular RNAs (circRNAs) during lung adenocarcinoma (LUAD) progression. Herein, we explored a novel circRNA, circ_0129047, and detailed its mechanism of action. The expression of circ 0129047, microRNA-665 (miR-665), and protein tyrosine phosphatase receptor type B (PTPRB) in LUAD tissues and cells was determined using reverse transcription quantitative polymerase chain reaction and Western blotting. Cell Counting Kit8 and colony formation assays were conducted to detect LUAD cell proliferation, and western blotting was performed to quantify apoptosis-related proteins (Bcl2 and Bax). Luciferase reporter and RNA immunoprecipitation assays were used to validate the predicted interaction between miR-665 and circ_0129047 or PTPRB. A xenograft assay was used for the in vivo experiments. Circ_0129047 and PTPRB were downregulated in LUAD tissues and cells, whereas miR-665 expression was upregulated. Overexpression of circ_0129047 suppresses LUAD growth in vivo and in vitro. Circ_0129047 is the target of miR-665, and the miR-665 mimic ablated the antiproliferative and pro-apoptotic phenotypes of LUAD cells by circ_0129047 augmentation. MiR-665 targets the 3'UTR of PTPRB and downregulates PTPRB expression. PTPRB overexpression offsets the pro-proliferative potential of miR-665 in LUAD cells. Circ_0129047 sequestered miR-665 and upregulated PTPRB expression, thereby reducing LUAD progression, suggesting a promising approach for preventing LUAD.