• Title/Summary/Keyword: Micro mixer

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Microfluidic Device for Bio Analytical Systems

  • Junhong Min;Kim, Joon-Ho;Kim, Sanghyo
    • Biotechnology and Bioprocess Engineering:BBE
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    • v.9 no.2
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    • pp.100-106
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    • 2004
  • Micro-fluidics is one of the major technologies used in developing micro-total analytical systems (${\mu}$-TAS), also known as “lab-on-a-chip”. With this technology, the analytical capabilities of room-size laboratories can be put on one small chip. In this paper, we will briefly introduce materials that can be used in micro-fluidic systems and a few modules (mixer, chamber, and sample prep. modules) for lab-on-a-chip to analyze biological samples. This is because a variety of fields have to be combined with micro-fluidic technologies in order to realize lab-on-a-chip.

Development of A New Device for Controlling Infinitesimal Flows inside a Lab-On-A-Chip and Its Practical Application (랩온어칩 내부 미세유동 제어를 위한 새로운 장치의 개발 및 적용)

  • Kim, Bo-Ram;Kim, Guk-Bae;Lee, Sang-Joon
    • 유체기계공업학회:학술대회논문집
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    • 2006.08a
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    • pp.305-308
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    • 2006
  • For controlling micro-flows inside a LOC (lab-on-a-chip) a syringe pump or an electronic device for EOF(electro-osmotic flow) have been used in general. However, these devices are so large and heavy that they are burdensome in the development of a portable micro-TAS (total analysis system). In this study, a new flow control system employing pressure chambers, digital switches and speed controllers was developed. This system could effectively control the micro-scale flows inside a LOC without any mechanical actuators or electronic devices We also checked the feasibility of this new control system by applying it to a LOC of micro-mixer type. Performance tests show that the developed control system has very good performance. Because the flow rate in LOC is controlled easily by throttling the speed controller, the flows in complicate microchannels network can be also controlled precisely.

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Micro-PIV Measurement of Water/Oil Two Phase Flow in a Y-Junction Microchannel (Y형 마이크로채널에서의 물/기름 2상 유동에 대한 Micro-PIV 측정)

  • Yoon,Sang-Youl;Ko, Choon-Sik;Kim, Kyung-Chun
    • Transactions of the Korean Society of Mechanical Engineers B
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    • v.28 no.6
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    • pp.682-687
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    • 2004
  • Y-junction microchannels are widely used as a flew mixer. Fluids are entered from two branch channels and merged together at a combined channel. In this study, we suggest a simple method to create the fluid digitization using flow instability phenomena. Two immiscible liquids (water/oil) are infused continuously to each Y-junction inlets. Because of the differences in fluid and flow properties at the interface, oil droplet is formed automatically followed by flow instability. In order to clarify the hydrodynamic aspects involved in oil droplet formation, a quantitative flow visualization study has performed. Highly resolved velocity vector fields are obtained by a micro-PIV technique, so that detail flow structures around the droplet are illustrated. In this study, fluorescent particles were mixed with water only for visualization of oil droplet and velocity field measurement in water flow.

Evaluation of Lumen-loaded Fiber with Micro Metal Particles (미세금속입자의 루멘충전 특성평가)

  • Sung, Yong-Joo;Jung, Woong-Ki;Lee, Ji-Young
    • Journal of Korea Technical Association of The Pulp and Paper Industry
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    • v.44 no.4
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    • pp.99-107
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    • 2012
  • In this study, the lumen loading technology for preparing magnetic papers were evaluated. The rice husk fiber, softwood kraft pulp, hardwood kraft pulp were applied and the morphological properties of pits on the those fibers were investigated with SEM. The softwood kraft pulp had the bigger size of pits, $3{\sim}5{\mu}m$ in diameter, which resulted in higher loading amount. The comparison of two methods for lumen loading such as the low concentration method with the disintegrator and the high concentration method with the Hobart mixer showed the Hobart mixer could resulted in the higher efficiency. The conditions of lumen loading process such loading time, addition amount of metal particles and addition of PEI were also evaluated. The magnetic hysteresis loop of handsheet samples made of lumen loaded fiber with $Fe_3O_4$ and $Fe_2O_3$ were examined. The differences in magnetic properties could be found according to the ferrite types.

A NUMERICAL STUDY ON FLOW AND STIRRING CHARACTERISTICS IN A MICROCHANNEL WITH PERIODIC ARRAY OF CROSS BAFFLES (엇갈림 배플 구조의 마이크로 채널 내 유동 및 혼합 특성에 관한 수치해석적 연구)

  • Heo, S.G.;Heo, Y.G.;Heo, H.S.;Suh, Y.K.
    • 한국전산유체공학회:학술대회논문집
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    • 2006.10a
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    • pp.159-162
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    • 2006
  • In the microfluidics devices the most important thing is mixing efficiency of various fluids. In this study a newly designed mixer is proposed to enhance the mixing effect with the purpose to apply it to microchannel mixing in a short future. This design is composed of a channel with cross baffles periodically arranged on the both bottom and top surfaces of the channel. To obtain the flow patterns, the numerical computation was performed by using a commercial code, ANSYS CFX 10.0. To evaluate the mixing performance, we computed Lyapunov exponent and obtained Poincare sections.

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Experimental Study on Cement Cohesion Reduction Effect of Grout Mixer with Vibration Filter (진동필터가 설치된 그라우트 믹서의 시멘트 응집 저감 효과에 대한 실험적 연구)

  • Hwang, Sung-Pil;Jeoung, Jae-Hyeung;Kim, Chang-Yong;Lee, Woo-Je
    • The Journal of Engineering Geology
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    • v.28 no.1
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    • pp.61-67
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    • 2018
  • Grouting is reinforcement or cutoff method which uses the hardening agent which is typically represented by portland cement and injected into the ground or the structure. When mixing the cement in powder form with water, the particles tend to cohere each other. Once they cohered, the particle size tends to become larger while injection efficiency becomes lower. This study, in a bid to reduce the cohesion of cement, the screen was set inside the grout mixer so that the cement particles are separated while vibrating them. To validate the effect of vibration screen, comparison test was conducted by using ordinary portland cement, slag cement and micro cement. Viscosity test, bleeding test and grain-size analysis indicated that the characteristics varied significantly after passing through the vibration filter. It is expected that the vibration filter installed inside the grout mixer will reduce the cement cohesion when mixing with water.

Development of Micro Mixing Device with Using Ultrasonic Wave (초음파를 이용한 마이크로 혼합기 제작)

  • Jeon, Yongho;Choi, Byung-Joo;Kang, Seung-Joon;Kim, Dong-Kwon;Kim, Hyun-Jung;Lee, Moon Gu
    • Journal of the Korean Society of Manufacturing Technology Engineers
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    • v.22 no.3
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    • pp.459-464
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    • 2013
  • The purpose of a micro-mixing device is to enhance the mixing by increasing the diffusion effect between different types of flows. There have been many attempts to actively or passively increase mixing. However, those studies were limited to lab-scale experiments because the production of devices requires a series of processes, time, cost, and the mixing quality itself. For this reason, this study attempted to develop a quick and simple process for micro-mixing device fabrication by using conventional machining and bonding processes and applying ultrasonic waves from the outside of the mixing device. The mixing quality was quantified by using the mixing index, and the results showed that the proposed system increases the mixing from ~33% to ~10% with respect to the flow rates.

A Study on Characteristics of Aerobic Liquid-Composting using a Micro Air Diffusion and a Mixer System (미세기포와 교반을 이용한 호기성 액비특성에 관한 연구)

  • Gu, Bon-Woo;Oh, Dae-Min;Lee, Young-Shin
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.11 no.4
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    • pp.1354-1360
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    • 2010
  • The purpose of this study is to analyze the behavior of swine slurry wastewater from bogen, in the treatment of Aerobic Liquid-Composting treatment by Aerobic Liquid-Composting using a mixer and Micro Air Diffusion pH level was at the beginning and its rise was seemingly related to VFA. It appears that removal of BOD and COD are more effective by Aerobic than by Anaerobic. In terms of removal efficiency, it shows 70.9% of BOD and 39% of COD in M.A+Mix and 67.8% of BOD and 19% of COD in M.A. $NH_3-N$ decreases in all conditions, which is caused by both the characteristic of nitrogen and the rise of pH. $NO_3-N$ increases in all conditions. It is judged that the accumulation of $NO_3-N$ affects the reduction of the ratio of denitrification. In the result of the analysis of Manure in swine slurry of liquified fertilizer ingredients, content of Manure in swine slurry of liquified fertilizer ingredients in aerobic conditions (M.A+Mix) is higher than anaerobic conditions.

The Effect of Karman Vortex for Mixing in a Micro-channel with an Oscillating Micro-stirrer (진동 교반기가 있는 미소채널에서 혼합에 대한 Karman 와의 영향)

  • An, Sang-Joon;Maeng, Joo-Sung;Kim, Yong-Dae
    • Transactions of the Korean Society of Mechanical Engineers B
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    • v.30 no.2 s.245
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    • pp.144-152
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    • 2006
  • In order to consider the effect of Karman vortex for mixing, mixing indices are calculated for 4 models of micro channel flows driven from the combinations of a circular cylinder and a oscillating stirrer. And their results are compared to that of a simple straight micro channel flow(model I). The mixing rate is improved 5.5 times by Karman vortex (model II) and 11.0 times by the stirrer(model III) respectively. In case of successive mixing by the cylinder and the stirrer(model IV), $27\%$ of shortening the channel length for the complete mixing as well as 1.37 times improvement of mixing efficiency then model III. And then, variation of mixing indices are much stable comparing with the others. Thus, it is found that the Karman vortex plays a good role as a pre-mixing method. The D2Q9 Lattice Boltzmann methods are used.