• The monthly packaging world
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• s.75
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• pp.188-190
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• 1999

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.9
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• pp.4039-4044
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• 2014

Background: The aim of this study was to investigate the anti-cancer effects and mechanisms of immunochemotherapy of 5-fluorouracil (5-FU) and interleukin-2 (IL-2) on non-small cell lung cancer (NSCLC) A549 cells. Materials and Methods: In order to detect whether 5-FU+IL-2 could effectively inhibit tumor growth in vivo, we established an A549-bearing nude mouse model. The cytotoxicity of natural killer (NK) cells was evaluated using a standard chromium release assay. To evaluate the relevance of NK cells in 5-FU+IL-2-mediated tumor inhibitory effects, we depleted NK cells in A549-bearing mice by injecting anti-asialo-GM-1 antibodies. Effects of 5-FU+IL-2 on the expression and promoter activity of NKG2D ligands (MICA/MICB) in A549 cells in vitro were also assessed. Results: In A549-bearing nude mice, combination therapy significantly inhibited tumor growth in comparison with monotherapy with 5-FU or IL-2 and enhanced the recognition and lysis of tumor cells by NK cells. Further study of mechanisms showed that NK cells played a vital role in the anticancer immune response of 5-FU+IL-2 immunochemotherapy. In addition, the combination therapy synergistically stimulated the expression and promoter activity of MICA/MICB. Conclusions: 5-FU and IL-2 immunochemotherapy significantly inhibited tumor growth and activated NK cytotoxicity in vivo, and these effects were partly impaired after depleting NK cells in tumor-bearing mice. Combination treatment of 5-FU and IL-2 upregulated the expression and the promoter activity of MICA/MICB in A549 cells, which enhanced the recognition of A549 cells by NK cells. All of the data indicated that immunochemotherapy of 5-FU and IL-2 may provide a new treatment option for patients with lung cancer.

• Journal of the Mineralogical Society of Korea
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• v.24 no.4
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• pp.313-320
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• 2011

Mica-type phyllosilicate particles in the shales of the Manhang formation at the Taeback area in the Kangwon Province were studied using electron probe microanalysis (EPMA) and transmission electron microscopy (TEM). The average chemical formula of the mica-type phyllosilicate mineral analysed by EPMA is $K_{1.35}(Fe_{0.18}Mg_{0.03}Al_{3.86})(Si_{6.55}Al_{1.45})O_{20}(OH)_4$. Low K contents compared to the ideal chemistry of muscovite indicate the presence of illite in the mica-type phyllosilicate particle. X-ray diffraction study showed that pyrophyllite commonly coexists with muscovite in the shales from the Manhang Formation. TEM observations showed both the interlayer and intralayer mixing of $9.3-{\AA}$ pyrophyllite and $10-{\AA}$ muscovite layers. The low K content of the mica-type phyllosilicates apparently come from the close mixing of pyrophyllite and muscovite.

• Journal of the East Asian Society of Dietary Life
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• v.14 no.5
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• pp.513-518
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• 2004

The effect of polyethylene film(PE) packaging of golden mushroom wrapped with Korean paper containing 20% mica powder on the changes in weight, color, texture, PPO activity, number of total microbe(TM) and sensory quality during storage at 10℃ were investigated. The experiments were divided to 3 groups(control; only PE packaging, KP; PE packaging wrapped with Korean paper up and down of the sample, KPM; PE packaging with Korean paper containing 20% mica powder up and down of the sample). The weight of the mushroom in the KPM was the lowest until 9 days-storage, but the weight was the highest at 15 days-storage, showing 12.5% higher against the initial weight. L* values of the mushrooms in the control and KP treatment were decreased, but the value in the KPM treatment was maintained as the same of the initial value during storage. The increasing rate of a* and b* values in the all plots during storage was the lowest in KPM and in order of KPM

• Journal of Korea Foundry Society
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• v.17 no.6
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• pp.569-576
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• 1997

Coating materials for Evaporative Pattern Casting (EPC) process have been developed to investigate the effect of refractories on coating material properties. Three types of developed and one foreign coating materials were used. The former designated as A, B, C and the latter named S.K. The refractory of coating material A is spherical shape of zirconia, and the ones of B, C and S.K. is flake shape of mica. Strength, permeability at room and elevated temperature, anti-sand attachability and carbon residuary were evaluated at each coating materials. Permeability measurement device for elevated temperature was also designed. The zirconia type of coating material had excellent permeability, on the other hand the mica type had good strength and anti-sand attachability. It was found that the refractories were not broken during casting, so permeability indicated same trend at both room and elevated temperature. Based on results, coating material contained small size of mica which is designated as B has the best combination for cast iron.

• Economic and Environmental Geology
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• v.14 no.3
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• pp.123-142
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• 1981

Granitic complex in the Woosanbong area is composed of schistose granite, two-mica granite, biotite granite, porphyritic granite and pink feldspar granite in order of intrusion. In their boundary aspects, the gradational change between porphyritic granite and pink feldspar granite is observed in field relations. All the granites of the complex are classified to quartz monzonite by the modal compositions following Bateman's classification (1961) with the exception of pink feldspar granite which belongs to granite according to the petrographical classification. The first three granites are characterized by highly development of vein and/or lens-like pegmatites in their bodies, and two others contain green hornblende uniquely. These leucocratic two-mica granite shows an unusual character in ratio of muscovite to biotite 1: 0.7 to 1:13, and contains dominantly microcline. The content of muscovite varies in places in the field. Under the polarizing microscope it is revealed that the muscovite flakes occur as the products altered from biotite partly or completely, and it usually associates with chlorite flakes nearby. These features, therefore, suggests that biotite probably has been altered to muscovite and chlorite by hydration during deuteric processes. At the same stage, sericitization of plagioclase by the hydrolytic decomposition, and transformation of orthoclase to microcline may be taken place. Accordingly, it is obviously permissible to consider the two-mica granite as a kind of 'apo-granite' by deuteric alterations during the consolidation of magma.

• KIEE International Transactions on Electrophysics and Applications
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• v.3C no.2
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• pp.59-65
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• 2003

Electrical properties such as permittivity and tan$\delta$ of unaged (control) and aged (72 h at 18$0^{\circ}C$) mica/epoxy composites of 130 ${\mu}{\textrm}{m}$ thickness were measured and their surface conditions were characterized using scanning electron microscopy (SEM), Fourier transform infrared (FTIR), electron spectroscopy for chemical analysis (ESCA), differential scanning calorimetry (DSC) and thermogravimetric analysis (TGA). Both permittivity and tan6 of control specimens were higher than those of short-time aged specimens. FTIR results show a new peak at 1710 $cm^{-1}$ / for short-time aged specimens, originating from carbonyl group formed by the oxidation reaction during the aging process. ESCA results show that the binding energy at 532.9 eV representing the singlet state of oxygen ( $O_{1s}$) decreases by 13.7%, whereas that at 534.6 eV increases by 13.7%. Glass transition temperatures of control and short-time aged specimens are observed to be 95.4$^{\circ}C$ and 113.4$^{\circ}C$, which increase with the increase of aging time. TGA results indicate that the control specimens contain a smaller amount of volatile components than the short-time aged specimens.s.

• Proceedings of the Korean Vacuum Society Conference
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• 2011.08a
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• pp.159-159
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• 2011

최근 여러 화학 반응에 대해서 일층(1L) 그래핀(graphene)이 복층(multi-layered) 그래핀보다 10 배 이상의 높은 반응성을 보인다는 사실이 알려졌다. 본 실험에서는 기판의 편평도와 기판-그래핀 간의 상호작용이 그래핀의 반응성에 미치는 영향을 이해하기 위해서, AFM(atomic force microscopy)과 라만 분광법을 이용하여 그래핀의 기체상 고온 산화반응을 연구하였다. 기계적 박리법을 통해 산화실리콘(SiO2/Si)과 마이카(mica) 기판 위에 고착된 그래핀 시료를 대조군으로 비교하였다. AFM 형상 분석으로부터 편평도가 낮은 산화실리콘 위에서는 그래핀의 두께가 작을수록 산화 속도가 크다는 사실을 확인하였다. 그러나 편평도가 높은 마이카 기판 위에서는 단일층 그래핀의 산화 속도가 산화실리콘 기판 위에서보다 현저하게 감소하고 두 겹 이상의 두께에서는 반응성의 차이가 없음을 발견하였다. 특히 마이카 위의 단일층 그래핀에서는 복층 그래핀과는 달리 산화에 의한 식각이 거의 일어나지 않아 화학적 안정성이 증대되었음을 알 수 있었다. 본 연구는 기판의 표면구조와 상호 작용을 통해 그래핀의 화학적 특성을 조절 할 수 있다는 가능성을 보여 준다.

• Electrical & Electronic Materials
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• v.10 no.4
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• pp.327-333
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• 1997

Experiments on mechanical fatigue were conducted using the specimens which were cut from hydrogen cooled generator(rated 22kV and 50OMW) stator windings. We have investigated the aged mechanism of mica/epoxy insulation systems under air or hydrogen by both the tensile and compressive loadings. The fracture of generator stator windings is generally affected by mechanical stress. Thus, the tensile strength test were conducted. In this case, the maximum strength and strain are quite different between sound and aged specimens. It is observed that low bonded interface parts of tapes generally have lower strength than those of normal tapes which causes stress. In order to estimate the effects of cyclic load by the electromagnetic forces while the generator starts/stops, the mechanical fatigue test was also conducted. It is confirmed that the equation of expected life depends on stress amplitude and number of cycles. Though the stress amplitude and number of cycles are very tiny, the tensile fatigue of aged specimens under hydrogen atmosphere is bigger than those under air. In the case of hydrogen atmosphere, the tensile stress gives bigger effect than the compressive one.

• Proceedings of the IEEK Conference
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• summer
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• pp.92-96
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• 2004

The researches of the emotions are currently great interest in speech processing as well as in human-machine interaction domain. In the recent years, more and more of researches relating to emotion synthesis or emotion recognition are developed for the different purposes. Each approach uses its methods and its various parameters measured on the speech signal. In this paper, we proposed using a short-time parameter: MFCC coefficients (Mel­Frequency Cepstrum Coefficients) and a simple but efficient classifying method: Vector Quantification (VQ) for speaker-dependent emotion recognition. Many other features: energy, pitch, zero crossing, phonetic rate, LPC... and their derivatives are also tested and combined with MFCC coefficients in order to find the best combination. The other models: GMM and HMM (Discrete and Continuous Hidden Markov Model) are studied as well in the hope that the usage of continuous distribution and the temporal behaviour of this set of features will improve the quality of emotion recognition. The maximum accuracy recognizing five different emotions exceeds $88\%$ by using only MFCC coefficients with VQ model. This is a simple but efficient approach, the result is even much better than those obtained with the same database in human evaluation by listening and judging without returning permission nor comparison between sentences [8]; And this result is positively comparable with the other approaches.