• Title/Summary/Keyword: Methanol Synthesis

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Inhibitory Effect of Methanol Extract of Doenjang on Growth and DNA Synthesis of Human Cancer Cells (된장 메탄올 추출물의 인체 암세포 성장 억제 효과 및 DNA 합성 저해 효과)

  • 임선영;이숙희;박건영
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.33 no.6
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    • pp.936-940
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    • 2004
  • Doenjang (Korean soy paste) is one of the popular soybean based fermented foods in Korea. This study investigated the growth and DNA synthesis inhibitory effect of doenjang methanol extracts on AGS human gastric adenocarcinoma cells, Hep 3B human hepatocellular carcinoma cells and HT-29 human colon cancer cells. In order to determine an anticancer effect of doenjang methanol extracts, other soybean fermented foods and original materials were compared. The treatment of doenjang methanol extracts (200 $\mu\textrm{g}$/mL) to the AGS, Hep 3B and HT-29 cancer cells inhibited the growth of cancer cells by 80%, 77% and 86%, respectively. Compared to other soybean fermented foods and original materials, doenjang methanol extracts showed the highest growth inhibitory effect on different cancer cells. In addition, doenjang methanol extracts (200 $\mu\textrm{g}$/mL) significantly inhibited DNA synthesis of AGS and Hep 3B cancer cells by 76% and 59%, respectively. These results suggested that this anticancer effect of doenjang may be due to specific active compounds, which will be newly produced during soybean fermented process and not contained in soybean.

Direct Methanol Synthesis by Partial Oxidation of Methane (메탄의 부분산화에 의한 메탄올 직접 합성)

  • Kim, Young-Kook;Lee, Kwang-Hyeok;Hahm, Hyun-Sik
    • Journal of the Korean Applied Science and Technology
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    • v.30 no.4
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    • pp.649-655
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    • 2013
  • Methanol was directly produced by the partial oxidation of methane with perovskite and mixed oxide catalysts. Perovskite ($ABO_3$) catalysts were prepared by the malic acid method with changing A and B site components. Three-component mixed oxide catalysts that have Mo and Bi as a main component were prepared by the co-precipitation method. Among the perovskite catalysts, $SrCrO_3$ showed the highest methanol selectivity of 11% at $400^{\circ}C$. For the three-component mixed oxide catalysts, there were no remarkable changes in methane conversion. Among the mixed oxide catalysts, Mo-Bi-Cr mixed oxide catalyst showed the highest methanol selectivity of 15.3% at $400^{\circ}C$. The catalytic activity and methanol selectivity of the three-component mixed oxide catalysts were directly proportional to the surface area of the catalysts.

Study on Synthesis of Dimethyl Ether Using Silica Membrane Reactor (Silica막 반응기를 이용한 Dimethyl Ether 합성에 관한 연구)

  • Sea Bongkuk;Youn Min-Young;Lee Kew-Ho
    • Membrane Journal
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    • v.15 no.4
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    • pp.330-337
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    • 2005
  • Water selective silica membranes were prepared fur use as membrane reactor for synthesis of dimethyl ether (DME) by methanol dehydration. Silica membranes formed on a Porous SUS tube by ultrasonic spray Pyrolysis (USP) and chemical vapor deposition (CVD) using tetraethoxysilane (TEOS) as precursor. The CVD-derived membranes formed higher level of trade-off line between water permeance and water/methanol selectivity than that of the USP-derived membranes. The membrane reactor possessing water permeance of $1.2\times10^{-7}\;mol\;{\cdot}\;m^{-2}\;{\cdot}\;S^{-1}\;{\cdot}\;Pa^{-1}$ and water/methanol selectivity of 10 exhibited increase in methanol conversion of about $20\%$ comparing to conventional reactor system. These findings led us to conclude that the dehydration membrane reactor simultaneously separating the water vapour produced in the reaction zone was effective in increasing the reaction conversion.

Inhibitory Effect of Melanogenesis and Anti-inflammatory Effect of Elsholtzia ciliata Extract and Its Application as a Cosmeceutical Ingredient (향유의 멜라닌 생성 억제효과 및 항염효과와 화장품 원료로서의 특성)

  • Lee, Dae-Woo;Kim, Young-Jin;Kim, Young-Sil;Eom, Sang-Yong;Kim, Jong-Heon
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.32 no.4 s.59
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    • pp.219-225
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    • 2006
  • In this study, we evaluated anti-oxidation, whitening and anti-inflammatory effects of Elsholtzia ciliata extract for use as the cosmeceuticals. Elsholtzia ciliata extracts (30, 70 and 100% methanol extract) exhibited a significant tree radical scavenging effect (up to 80% over 0.025% concentration of 30 and 70% methanol extract, over 0.01% concentration of 100% methanol extract) against DPPH radical generation and showed a significant inhibitory effect (up to 80% over 0.1% concentration) on melanin synthesis in B-16 Melanoma cells. We separated 4 fractions from Elsholtzia ciliata extract (70% methanol extract) by MPLC. The 1st, 2nd, and 3rd fractions showed anti-oxidation (DPPH radical scavenging activity and suppressive effect on Mn-SOD), whitening(inhibitory effect on melanin synthesis) and anti-inflammatory (suppressive effects on $IL-1{\alpha}$, IL-6, COX-2, and total NO synthesis) effects.

Effect of Metal Oxide Catalysts and Ionic Liquids on the Synthesis of Methyl Carbamate and Dimethyl Carbonate from Urea and Methanol under High Pressure Reaction System (고압반응 하에서 요소와 메탄올을 사용한 메틸카바메이트와 디메틸카보네이트 제조에 관한 금속산화물 촉매 및 이온성액체의 영향)

  • Kim, Yun-Min;Kim, Chul-Ung;Koh, Jae-Cheon;Park, Dae-Won;Koo, Kee-Kahb
    • Korean Chemical Engineering Research
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    • v.49 no.6
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    • pp.732-738
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    • 2011
  • Effect of metal oxide catalysts and ionic liquids on the synthesis of methyl carbamate(MC) and dimethyl carbonate (DMC) from urea and methanol was investigated in a high pressure reaction system. In closed system, MC yield from urea and methanol reached almost 100% at reaction temperature over $150^{\circ}C$ without catalyst, whereas DMC yield of 1.5% under was obtained irrespective of catalysts used. In DMC synthesis from MC and methanol, $ZnCl_{2}$ showed the highest catalytic activity and led to the DMC yield of 16.3% under optimal conditions. Furthermore, DMC yield can be enhanced by the simultaneous application of ionic liquids with nano-sized catalysts in semi-continuous reaction system.