• 부모자녀건강학회지
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• 제21권1호
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• pp.50-60
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• 2018

Purpose: This study is a systematic literature review and meta-analysis study conducted to identify the effects of breastfeeding intervention program on premature infants by integrating and analyzing the results of randomized controlled trials and non-randomized trials. Methods: The literature review process was based on the PRISMA (Preference Reporting Items for Systematic Reviews and Meta-Analyzes) guideline. Data retrieval and collection were conducted from May 25 to May 30, 2018, and the articles analyzed were all domestic papers retrieved from the database. Two reviewers independently select the studies and assessed methodological risk of bias of studies using the Cochrane criteria. The topics of breastfeeding interventions were analyzed using descriptive analysis and the effects of intervention were meta-analyzed using the R program. Results: Finally, eight papers were included in the systematic review and meta-analysis. The breastfeeding intervention program for premature infants showed a significant increase in the self-efficacy and the amount of pumping and baby's hight. Conclusion: This study has some limitations due to the few randomized controlled trials and non-randomized trials comparing breastfeeding for premature babies in Korea. Therefore, it needs to be integrated with the research conducted in other countries.

• Asian Pacific Journal of Cancer Prevention
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• 제13권8호
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• pp.3717-3721
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• 2012

Purpose: Any association between the CYP1A1 Ile462Val polymorphism and endometrial cancer risk remains inconclusive. For a more precise estimate, we performed the present meta-analysis. Methods: PUBMED, OVID and EMBASE were searched for the studies which met inclusion criteria. Data in all eligible studies were evaluated and extracted by two authors independently. The meta-analysis estimated pooled odds ratio (OR) with 95% confidence interval (CI) for endometrial cancer risk attributable to the CYP1A1 Ile462Val polymorphism. Results: A total of 7 studies were included in this meta-analysis. The results indicated no association between endometrial cancer risk and the CYP1A1 Ile462Val polymorphism (for Val vs Ile allele model [OR 1.09, 95% CI 0.73-1.62]; for Val.Val vs Ile.Ile genotype model [OR 1.54, 95% CI 0.56-4.23]; for (Ile.Val + Val.Val) vs Ile.Ile genotpye model [OR 1.08, 95% CI 0.71-1.63]; for Val.Val vs (Ile.Ile + Ile.Val) genotype model [OR 1.46, 95% CI 0.53-4.04]). Conclusions: This meta-analysis suggests that there is no association between endometrial cancer risk and the CYP1A1 Ile462Val polymorphism.

• Asian Pacific Journal of Cancer Prevention
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• 제13권7호
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• pp.3109-3112
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• 2012

Background: Many studies have focused on possible associations between the glutathione S-transferase M 1 (GSTM1) null genotype and risk of renal cell carcinoma (RCC), but the impact remains unclear owing to obvious inconsistencies among the findings. The present study aimed to quantify the strength of any association in a meta-analysis. Methods: We searched the PubMed, Embase and CBM databases for studies concerning the association between the GSTM1 null genotype and risk of RCC. We estimated the summary odds ratio (OR) with its 95% confidence intervals (95% CI) to assess the association. Results: The meta-analysis showed the GSTM1 null genotype was not associated with risk of RCC overall (OR = 1.04, 95% CI 0.92-1.18, P = 0.501). For Caucasians, the GSTM1 null genotype was also not associated with risk of RCC (OR=1.02, 95% CI 0.90-1.16, P = 0.761). The cumulative meta-analyses showed a trend of no obvious association between GSTM1 null genotype and risk of RCC as information accumulated. Sensitivity analyses by omitting those studies also did not materially alter the overall combined ORs. No evidence of publication bias was observed. Conclusion: Meta-analyses of available data show that the GSTM1 null genotype is not significantly associated with risk of renal cell carcinoma.

• 한국전문물리치료학회지
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• 제16권3호
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• pp.50-59
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• 2009

The aim of the study was to evaluate the effectiveness of exercise therapy on physical function of patients with anklyosing spondylitis (AS) through the systemic review and meta-analysis. The 54 studies were identified from computerized search of published researches on PubMed, Embase, CINAHL, PEDro, KISS, KERIS database until February, 2008 and review of reference lists. The main search terms were the combination "ankylosing spondylitis", "exercise", "spondyloarthropathy and exercise", "ankylosing spondylitis and physical therapy". The subgroup analysis was performed by the publication year, quality score, type of disease, content of intervention, intervention provider, type of intervention, method of intervention, intervention period and the point of outcome measured. Two reviewers independently selected trials for inclusion, assessed the quality and extracted the data. The result was as follows: The 10 trials were eligible for inclusion criteria, then the systematic review and meta-analysis was assessed on effectiveness of exercise therapy. The meta-analysis of 10 studies based on the random effect model showed that the exercise therapy was beneficial in treating the diseases (effect size .55; 95% confidence interval -.3.75~.61). The findings suggest that the exercise therapy would be appropriate to manage the physical function of AS with evidence based on Meta-analysis. Therefore, the exercise therapy supervised by physical therapist should be recognized as the essential approach to manage the AS and necessarily recommended to improve physical function.

• 한국국방경영분석학회지
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• 제33권1호
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• pp.59-74
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• 2007

컴퓨터 시뮬레이션 모델은 일반적으로 복잡할 뿐더러 운용 시 많은 시간이 소요된다. 따라서 분석의 편의를 위해 좀 더 간단한 메타모델을 수립할 필요가 있다. 본 논문에서는 워게임 모델 JANUS를 사용하여 전차 전투 상황을 묘사하고 이에 대한 메타모델을 수립하였다. 메타모델을 수립하기 위해, 데이터 수집방법으로는 8가지의 실험계획법을, 모델링 방법으로는 2차 반응표면분석과 인공신경망을 고려하였다. 수립된 메타모델의 상대적 성능은 예측치의 평균제곱오차를 기준으로 비교하였다. 본 논문에서 고려한 전투상황에 대해서는 대체적으로 2차 반응표면 모형이 인공신경망 모형보다 더 높은 정확도를 보였으며, 실험계획법으로는 직교배열이나 최대최소거리 기준을 적용한 라틴 하이퍼큐브 계획법이 우수한 성능을 보였다.

• International Journal of Knowledge Content Development & Technology
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• 제10권1호
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• pp.7-20
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• 2020

For research data to be shared without legal, financial and technical barriers in the Open Science era, data repositories must have the functional requirements asked by DMP and CoreTrustSeal. In order to derive functional requirements for the data repository, this study analyzed the Data Management Plan (DMP) and CoreTrustSeal, the criteria for certification of research data repositories. Deposit, Ethics, License, Discovery, Identification, Reuse, Security, Preservation, Accessibility, Availability, and (Meta) Data Quality, commonly required by DMP and CoreTrustSeal, were derived as functional requirements that should be implemented first in implementing data repositories. Confidentiality, Integrity, Reliability, Archiving, Technical Infrastructure, Documented Storage Procedure, Organizational Infrastructure, (Meta) Data Evaluation, and Policy functions were further derived from CoreTrustSeal. The functional requirements of the data repository derived from this study may be required as a key function when developing the repository. It is also believed that it could be used as a key item to introduce repository functions to researchers for depositing data.

• 한국전자거래학회지
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• 제7권1호
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• pp.141-152
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• 2002

Data dictionary is a collection of meta-data, which describes data produced and consumed while performing business processes. Data dictionary is an essential element for business process standardization and automation, and has a fundamental role in ERP application management and customization. Also, data dictionary facilitates B2B processes by enabling painless integration of business processes between various enterprises. We implemented data dictionary support in SEA＋, a component- based scalable ERP system developed in ETRI, and found out that it's a plausible feature of business information system. We discovered that data dictionary promotes semantic, not syntactic, data management, which can make it possible to leverage viability of the tool in the coming age of more meta-data oriented computing world. We envision that business data dictionary is a firm foundation of adapting business knowledge, applications and processes into the semantic web based enterprise infra-structure.

• Asian Pacific Journal of Cancer Prevention
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• 제14권4호
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• pp.2413-2419
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• 2013

Background: Use of epidermal growth factor receptor inhibitors (EGFR-TKIs ) is now standard for non-small-cell lung cancer (NSCLC). However, the effects of EGFR-TKIs in maintenance therapy for advanced NSCLC patients are still unclear. The preent meta-analysis was performed to examine pooled data of randomized control trials (RCT) where EGFR-TKIs were compared against placebo in maintenance regimens for patients with advanced NCSLC to quantify potential benefits and determine safety. Methods: Several data bases were searched, including PubMed, EMBASE and CENTRAL, and we performed an internet search of conference literature. The endpoints were objective response rates (ORR), progression-free survival (PFS) and overall survival (OS). We performed a meta-analysis of the published data, using Comprehensive Meta Analysis software (Version 2.0). with a fixed effects model and an additional random effects model, when applicable. The results of the meta-analysis are expressed as hazard ratios (HRs) or risk ratios (RRs), with their corresponding 95% confidence intervals (95%CIs). Results: The final analysis included six trials, covering 3,758 patients. Compared with placebo, EGFR-TKIs maintenance therapy improved ORR and PFS for patients with advanced NSCLC, the difference being statistically significant (P<0.05), but proved unable to prolong patients' OS. The main adverse reactions were diarrhea and rashes. Conclusion: EGFR-TKIs demonstrated encouraging efficacy, safety and survival when delivered as maintenance therapy for patients with advanced NSCLC after first-line chemotherapy, especially for the patients who had adenocarcinomas, were female, non-smokers and patients with EGFR gene mutations.

• Journal of Korean Neurosurgical Society
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• 제63권4호
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• pp.455-462
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• 2020

Objective : Recent studies have reported that arachnoid plasty (ARP) using gelatin sponges with fibrin glue reduced the occurrence of chronic subdural hematoma (CSDH) following clipping surgery for unruptured intracranial aneurysm (UIA). This meta-analysis was conducted to collate further evidence for the efficacy of ARP in preventing postoperative CSDH. Methods : Data of patients who underwent clipping surgery were extracted from PubMed, EMBASE, and Cochrane Central Register of Controlled Trials by two independent reviewers. A random effects model was used to investigate the efficacy of ARP by using odd ratios (ORs) and 95% confidence intervals (CIs). A meta-regression analysis for male sex was additionally preformed. Results : Data from six studies with 1715 patients were consecutively included. Meta-analysis revealed that ARP was significantly associated with lower rates of CSDH development after surgical clipping for UIA (ARP group vs. control group : 3.2% vs. 7.2%; OR, 0.40; 95% CI, 0.18-0.93; I²=44.3%; p=0.110). Meta-regression analysis did not highlight any modifying effect of the male sex on postoperative CSDH development (p=0.951). Conclusion : This meta-analysis indicated that ARP reduced the incidence rates of CSDH following clipping surgery for UIA. If feasible, ARP would be implemented as an additional surgical technique to prevent postoperative CSDH development during surgical clipping of UIA.

• 정보처리학회논문지A
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• 제13A권6호
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• pp.533-540
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• 2006

본 논문에서는 분산 환경 상에서 CFD(Computational Fluid Dynamics) 분석 프로그램을 편리하게 수행할 수 있도록 하는 그리드 시스템 META(Metacomputing Environment using Test-un of Application)의 설계 및 구현에 관하여 기술한다. 그리드 시스템 META는 CFD 프로그램 개발자들이 네트워크에 분산된 계산 자원들을 단일 시스템처럼 사용할 수 있도록 한다. 그리드 컴퓨팅과 관련하여 연구주제로는 고장허용, 자원 선택, 사용자 인터페이스 설계 등이 있다. 본 논문에서는 MPI(Message Passing Interface)로 작성된 SPMD(Single Program, Multiple Data) 구조의 병렬프로그램을 실행시키기 위한 자동 자원 선택방법을 활용하였다. 본 논문에서 제안한 자원 관리기법은 네트워크상의 전송지연 시간과 시험수행을 통해 얻어진 핵심루프의 경과시간을 이용한다. 전송지연시간은 병렬 프로그램이 복수의 시스템에 분산되어 수행될 때 수행 성능에 큰 영향을 주는 요인이다. CFD 프로그램들의 공통적인 특성 때문에 핵심루프 경과시간은 전체 수행시간을 예측할 수 있는 지표가 된다. 핵심루프는 CFD 프로그램의 전체 수행시간 중 90% 이상을 차지한다.