• 동의신경정신과학회지
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• 제31권3호
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• pp.169-186
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• 2020

Objectives: The purpose of this study was to provide clinical evidence to support the use of acupuncture combined herbal medicine for post-stroke depression. Methods: Studies were identified by searching Pubmed, EMBASE, Cochrane Library, NDSL, RISS, KMbase, KISS, and CNKI. Randomized controlled trials that verified effects of the acupuncture combined with the herbal medicine for PSD were included in this study. Literature searches of English, Chinese, and Korean databases were performed. Two authors independently extracted the data and assembled the study quality. Results: Of 698 RCTs screened, 17 RCTs were selected. Most of the studies had unclear risk of bias. Among the 17 RCTs, 10 were meta-analyzed. As for the outcome measurement, the effective rate and the HAMD were most commonly used. The meta-analysis of the studies revealed that the PSD cure effective rate in the acupuncture combined with herbal medicine group was higher than that in the Western medicine group (RR: 1.23, 95% CI: 1.14 to 1.33, p<0.00001, I²=0%). Also, the HAMD in the acupuncture combined with herbal medicine group was significantly different compared to the Western medicine group (MD -5.54, 95% CI -9.80 to -1.29, p=0.01, I²=99%). The quality of the selected RCTs was low. Conclusions: Acupuncture combined with herbal medicine is effective for treating post-stroke depression. However, It is worth noting that the included studies were of relatively poor quality. The sample sizes were also small. Based on the findings of this study, further investigations into the diagnosis and treatment of PSD are warranted.

• 공업화학
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• 제7권3호
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• pp.573-579
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• 1996

공업적 기포탑 반응기의 설계, scale-up, 조절, 개발 및 운전에 매우 긴요한 기초자료들을 얻기 위하여 실험 실적 규모의 기포탑 반응기에서 각 실험변수들이 ortho 붕산으로부터 meta 붕산의 생성 반응전환율에 미치는 영향을 연구하였다. 반응시간 및 압력, 반응물의 입자크기 및 기체 유속 등을 실험변수로 선택하였으며, 이들 실험변수들이 기포탑 반응기내의 기체 체류량에 미치는 영향들을 반응의 전환율과 연계하여 또한 검토하였다. 연구의 결과, 다음과 같은 최적 반응조건을 얻을 수 있었다 : 반응시간 ; 35~40(분), 반응압력 ; 92~95(kPa), 반응입자의 크기 ; $0.6{\times}10^{-3}(m)$ 이하, 기체 유속 ; 0.07~0.08(m/s).

• 대한한의학방제학회지
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• 제28권2호
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• pp.199-209
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• 2020

Objectives : The purpose of this systematic review is to confirm whether Gwibitang is beneficial in chronic fatigue syndrome (CFS). Methods : Clinical trials were searched from databases including Pubmed, Embase, Central Cochrane, CNKI, Wanfang, CQVIP, CiNii, OASIS, Koreamed, and NDSL. The eligible study design was limited into randomized controlled trial, quasi-randomized controlled trial and controlled clinical trial. The outcomes included general effectiveness as nominal scale, and fatigue severity, insomnia severity and quality of life as interval or ratio scale. The meta-analysis and assessment of risk of bias was performed based on the data extracted from the selected trials. Results : The results of eight randomized controlled trials (n=596) were included in the meta-analysis. The results of the synthesis showed Gwibitang is beneficial substantially for relieving and managing the general symptoms, and its heterogeneity was not in important level (RR 0.26 [95% CI 0.17, 0.39], Z=6.47, P<0.00001, I²=0%). Gwibitang was beneficial for alleviating fatigue (SMD -0.78 [95% CI -1.27, -0.30], Z=3.17, P=0.002), but its certainty was low. In case of insomnia, too few trials had been found and their risk of bias was substantial, so no conclusions had been brought to. Conclusions : We found an evidence that Gwibitang could be beneficial for managing and alleviating main symptoms in CFS patients.

• 한국문헌정보학회지
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• 제38권2호
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• pp.189-212
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• 2004

본 연구는 청소년을 대상으로 한 과학분야 메타검색시스템 및 교과별 디렉토리시스템을 구축하고 사용성을 비교$\cdot$평가하여 효율성을 입증하려 하였다. 이를 위해 청소년 대상 과학분야 메타검색시스템과 개별검색시스템 및 교과별 디렉토리시스템을 각각 개발하였으며, 주제별 디렉토리시스템은 개발하지 않고 국내의 대표적인 과학기관에서 운영하고 있는 시스템을 선정하여 비교하였다. 사용성 분석을 위하여 정량적 연구방법과 정성적 연구방법을 병행하였으며, 데이터 수집을 위한 조사도구로 설문조사와 면접조사, 관찰법, 생각을 소리내어 말하기 방법을 사용하였다. 본 연구에서 비교$\cdot$평가한 청소년 대상의 과학분야 정보시스템에 있어서는 메타정색시스템의 사용성이 개별검색시스템보다 높은 것으로 나타났으며, 수업과 연계된 일관된 접근점을 제공하는 교과별 디렉토리시스템이 주제별 디렉토리시스템보다 사용성이 더 높은 것으로 나타났다.

• 한국콘텐츠학회논문지
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• 제17권5호
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• pp.18-33
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• 2017

학교폭력의 연장선상에서 상시적으로 괴롭힘이 이루어지는 '사이버불링'이 심각한 사회적 문제로 대두되고 있다. 본 연구에서는 청소년 사이버불링에 관한 선행연구를 분석하여 사이버불링 가해행동에 미치는 개인, 가정, 또래, 학교, 사이버환경, 폭력경험 등과 관련된 변인들의 효과크기를 알아보았다. 국내학술논문 검색사이트(RISS)를 이용하여 2010년 1월 1일부터 2016년 10월 31일까지 학술지게제 논문 및 석 박사학위논문을 대상으로 '사이버불링', '사이버따돌림', '사이버폭력', '사이버괴롭힘', '온라인 및 SNS 또래괴롭힘' 이란 검색어로 선정된 총 43편의 논문을 대상으로 분석하였다. 그 결과 개인, 폭력경험 변인이 중간크기의 효과(0.28~0.29)를 나타냈고 또래, 가정, 사이버환경, 학교변수 순으로 작은 크기의 효과(0.08~0.13)를 나타냈다. 본 연구 결과는 청소년 사이버불링에 대한 교육적, 사회정책적 대응방안 마련과 직접적인 예방 및 개입을 위한 구체적 프로그램 개발의 기초자료로 활용될 것이다.

• 한국전문물리치료학회지
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• 제26권4호
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• pp.70-76
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• 2019

Background: An excessive pronated foot is defined as a flattening or complete loss of the medial longitudinal arch. Excessive foot pronation is considered to have high risk factors of overuse injuries in the lower limb. Various treatments have been investigated in attempts to control excessive pronation. Objects: This meta-analysis identifies the effects of an anti-pronation taping technique using different materials. Methods: The electronic databases used include MEDLINE, the Physiotherapy Evidence Database (PEDro), Science Direct, the Korean Studies Information Service System (KISS), the Research Information Sharing Service (RISS), the Korea National Library, and the Korean Medical Database (studies published up to July 31, 2019). The database search used the following keywords: "foot drop" OR "foot arch" OR "foot pronation" OR "flat foot (pes planus)" AND "taping" OR "support." Eight eligible studies were analyzed to determine the effectiveness of anti-pronation taping in study and control groups. Results: The overall random effect size (Hedges'g) of the anti-pronation taping technique was 0.147 (95% confidence interval [CI]: -.214 to .509). When the effect (Hedges' g) was compared by the type of tape material, rigid tape (RT; Lowdye taping) was .213 (95% CI: -.278 to .704) and kinesiotape (KT; arch support taping) was -.014 (95% CI: -.270 to .242). Based on this meta-analysis, it was not possible to identify the extent to which anti-pronation taping was effective in preventing navicular drop, improving balance, or changing foot pressure. Only three of the eight eligible studies applied KT on excessive pronated feet, and the outcome measure areas were different to those of the RT studies. The KT studies used EMG data, overall foot posture index (FPI) scores, and rear foot FPI scores. In contrast, the RT studies measured navicular heights, various foot angles, and foot pressure. Conclusion: This review could not find any conclusive evidence about the effectiveness of any taping method for patients with pronated feet. Future studies are needed to develop the anti-pronation taping technique based on the clinical scientific evidence.

• 대한한방내과학회지
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• 제42권4호
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• pp.605-621
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• 2021

Objectives: The purpose of this review is to assess the efficacy and safety of Hwangryunhaedok-tang for type 2 diabetes without complications by systemic review and meta-analysis of randomized controlled trials (RCTs). Methods: We searched the following up to March 31. 2021: PubMed, EMBASE, The Cochrane Library, CNKI, CiNii, KISS, KMBASE, OASIS, ScienceON. Data extraction and assessment of Cochrane's risk of bias (RoB) tool were performed by two independent authors, and if there was disagreement between two researchers, it was resolved through the intervention of a third researcher. Results: A total of seven trials are included in this systemic review. The treatment group (Hwangryunhaedok-tang plus conventional treatment) showed more statistically significant effects than did the control group (conventional treatment only) in fasting plasma glucose level, 2-hour postprandial plasma glucose level, glycated hemoglobin A1c, fasting insulin level, and HOMA-IR. There was no significant difference between the treatment group (Hwangryunhaedok-tang alone) and the control group (metformin alone). Conclusion: Hwangryunhaedok-tang might have efficacy and safety in controlling blood sugar level and improving insulin-resistance. However, the number of studies included in the meta-analysis was insufficient, and the Hwangryunhaedok-tang used in the included studies was not standardized. Also, the quality of the involved studies was generally low. Therefore, further studies are needed to determine the efficacy and safety of Hwangryunhaedok-tang treatment for type 2 diabetes mellitus.

• International Neurourology Journal
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• 제22권4호
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• pp.275-286
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• 2018

Purpose: OnabotulinumtoxinA (BoNT-A) is a promising therapy for treating neurogenic detrusor overactivity (NDO) in individuals with spinal cord injury (SCI). This systematic review and meta-analysis aimed to carry out an in-depth review and to make an objective estimation of the efficacy and safety of BoNT-A on NDO after SCI. Methods: The PubMed, Embase, and Cochrane databases were searched for all relevant articles published from 2001 to 2016 that referred to NDO, SCI, and BoNT-A or botulinum toxin A. All data were recorded in an Excel spreadsheet by 2 individual reviewers. Review Manager version 5.3 was used to carry out the meta-analysis. Results: This analysis included 17 studies involving 1,455 patients. Compared with placebo and baseline, BoNT-A was effective in increasing maximum cystometric capacity, volume at first involuntary detrusor contraction, cystometric bladder capacity (all P<0.00001), compliance (P=0.001), and the number of patients with complete dryness (P=0.0003), and decreasing detrusor pressure, the number of patients with no involuntary detrusor contractions, the maximum flow rate, the incidence of detrusor overactivity (all P<0.00001), and the number of urinary incontinence episodes (P=0.001). There were no statistically significant differences between doses of 200 U and 300 U or between injections into the detrusor and submucosa. There were no life-threatening adverse events. Conclusions: BoNT-A is effective and safe in treating NDO after SCI. There were no statistically significant differences between doses of 200 U and 300 U or between injecting into the detrusor and submucosa. However, more high-quality randomized controlled trials are still needed.

• 한국컴퓨터정보학회논문지
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• 제24권1호
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• pp.121-128
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• 2019

An Internet of Things(IoT) technology which provides intelligent services by combining context-awareness based intelligences, inter-communication is made of between things and things or between things and person through the network connected with intelligent things is spreading rapidly. Especially as this technology is converged into smart device, mobile, cloud, big data technologies, it is applied into various domains. Therefore, this is different from existing Web or Mobile Application. New types of IoT applications are emerging by adapting IoT into Web or mobile. Because IoT application is not only focused on software but also considering hardware or things aspect, there are limitations existing development process. Existing development processes don't consider analysis and design techniques considering both hardware and things. We propose not only a meta-model for development process which can support IoT application's development but also meta-models for main activities in this paper. Especially we define modeling elements by using UML's extension mechanisms, provide development process, and suggest design techniques how to apply those elements into IoT application's modeling phase. Because there are many types of IoT application's type, we propose an Android and Arduino-based on IoT application as a case study. We expect that proposed technique can be applied into many of various IoT application development and design with a form of flexible and extensible as well as main functionalities or elements are more concretely described. As a result, it brings IoT application's flexibility and the effect of quality improvement.

• 디지털융복합연구
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• 제17권11호
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• pp.149-156
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• 2019

정보기술의 활용이 보편화되면서 대중과 연구자 모두 정보 프라이버시 문제에 대한 관심이 높아지고 있다. 이러한 문제에 대한 연구가 기하급수적으로 증가하면서 연구결과에 대한 전반적인 이해가 어려워졌다. 이에 따라 과거연구에 대한 체계적인 검토가 요구된다. 본 연구는 정보 프라이버시 연구에 핵심적인 네 가지 연구개념을 두 가지 연구모형으로 설정하고 기존 연구에서 수집된 데이터를 이용하여 실증 분석하였다. TSSEM이라는 정량적 메타분석 기법이 적용되었는데, 이 기법은 MASEM의 한 가지로서 구조방정식모형과 메타분석 기법을 통합하여 분석하는 기능을 제공한다. 분석결과는 위험 중심적 모형이 염려 중심적 모형과 비교하여 보다 높은 모형 적합도를 나타내었다. 본 연구의 결과는 전통적인 염려 중심적 모형의 설명력에 의문을 제시하며, 사용자의 프라이버시 정보 제공의도를 설명하기 위하여 위험 중심적 모형을 고려할 필요가 있다는 점을 시사한다.