• 성인간호학회지
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• 제20권5호
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• pp.675-684
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• 2008

Purpose: The purpose of this study was to examine the relationship among cognitive function, depression, social support, and self-care in elderly with hypertension. Methods: The subjects were 132 elderly with hypertension living in Seoul, Korea. Data were collected through face-to-face interviews using the Korean version of Mini-Mental State Examination(MMSE-K), Short form geriatric depression scale, social support questionnaire 6, and hypertension self-care scale. Results: Thirty-four percent of the subjects had questionable dementia and forty-two percent of the subjects were depressed. Means for social support were 2.40 for network size and 4.07 for satisfaction. The mean score of hypertension self-care was 60.34, indicating that the subjects took care of themselves moderately well. Cognitive function was negatively related to depression. Social support network and satisfaction were negatively related to depression. Self-care was negatively related to social support network. Conclusion: Programs are needed for elderly with hypertension to improve their cognitive function, depression, and social support. Also further studies are needed to confirm the factors related to self-care in the elderly with hypertension.

• 한국화재소방학회논문지
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• 제32권1호
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• pp.116-121
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• 2018

본 연구는 소방공무원의 임파워먼트와 가족기능 수준이 우울에 미치는 영향을 알아봄으로써 소방공무원의 우울에 관한 예방 차원의 실천 방안을 마련하는데 도움을 주고자 하였다. 이를 위하여 경기지역 소방공무원 351명을 대상으로 유의표집 방식으로 조사하였다. 조사결과, 소방공무원의 우울에 임파워먼트와 가족기능이 모두 유의미한 영향을 미치는 것으로 나타났다. 본 연구결과를 토대로, 소방공무원의 정신건강 예방을 위해 내적 대처자원으로서 각 개인의 임파워먼트를 적용해 볼 수 있는 가능성을 보여주었다는 점과 소방공무원 가정의 가족기능을 강화하기 위한 다양한 대안이 필요하며, 가족의 건강성 회복을 이끌어내기 위해 예방차원의 효과적인 '일과 삶의 균형' 정책의 적극적 도입과 지원을 제안하였다.

• 한국수자원학회:학술대회논문집
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• 한국수자원학회 2010년도 학술발표회
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• pp.132-139
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• 2010

The river technology of Japan was highly developed and achieved much result in flood protection, water use and the environment. Nowadays, the function which is requested to the river is changes because the society changes from growth to maturity. In this study, we suggest the functions of the river in the maturity society about future welfare, medical care and education based on field research of case study. In this research, we pay attention to the functions related with culture, one) function of healing, mental stress improvement and life, two) function of landscape, education and recreation. And this paper proposed the usage of the river where adopt to the times, a function and the value of "the river as the space". We made a questionnaire to 187 river managers, and 90% of answers wear positive for use the river as the medical aspect, health and the welfare. Furthermore, based on research result of hospitals and welfare facilities which used a river for their activities, we suggest to develop and use the river walk, to design a city and rivers as one, and to use many facilities which are located on river front more active, those are improve the new river functions.

• 한국초등과학교육학회지:초등과학교육
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• 제37권4호
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• pp.416-429
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• 2018

In social constructivist teaching, knowledge construction is achieved through learners' collective social interaction. Vygotsky argued that this process is mediated with language use, and the development of higher order thinking is realized through the transition from inter-personal psychological functions to intra-personal psychological functions. In so doing scientific concepts are internalized to learners. This study examined the third grade elementary students' inter/intra-personal psychological functions and their internalization processes during social constructivist teaching plan about strata and fossils. The lessons were designed along with Wells' dialogic inquiry and Leach and Scott's social constructivist teaching-learning sequences. Results showed that a teacher's utterances of talking with questioning to switch attention, creating cognitive disequilibrium, and expanding the width of students' opinions could make effective inter-personal psychological function. In addition, a learner's inner speech expressed into social discourse through talking about personal experiences, comparing epistemic idea with visual representation, or applying to different situation showed his/her intra-personal psychological function. Some cases of learners' internalization through language use could be at the stage of knowledge building and understanding of the spiral of knowing, but not all. Thus it is argued that a teacher's deeper insight into Vygotskian social constructivist teaching can make elementary science classroom teaching more effective in their inter/intra-psychological functions.

• BMB Reports
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• 제52권5호
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• pp.304-311
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• 2019

The cytoplasmic FMR1-interacting protein family (CYFIP1 and CYFIP2) are evolutionarily conserved proteins originally identified as binding partners of the fragile X mental retardation protein (FMRP), a messenger RNA (mRNA)-binding protein whose loss causes the fragile X syndrome. Moreover, CYFIP is a key component of the heteropentameric WAVE regulatory complex (WRC), a critical regulator of neuronal actin dynamics. Therefore, CYFIP may play key roles in regulating both mRNA translation and actin polymerization, which are critically involved in proper neuronal development and function. Nevertheless, compared to CYFIP1, neuronal function and dysfunction of CYFIP2 remain largely unknown, possibly due to the relatively less well established association between CYFIP2 and brain disorders. Despite high amino acid sequence homology between CYFIP1 and CYFIP2, several in vitro and animal model studies have suggested that CYFIP2 has some unique neuronal functions distinct from those of CYFIP1. Furthermore, recent whole-exome sequencing studies identified de novo hot spot variants of CYFIP2 in patients with early infantile epileptic encephalopathy (EIEE), clearly implicating CYFIP2 dysfunction in neurological disorders. In this review, we highlight these recent investigations into the neuronal function and dysfunction of CYFIP2, and also discuss several key questions remaining about this intriguing neuronal protein.

• 한국콘텐츠학회논문지
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• 제9권7호
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• pp.202-210
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• 2009

본 연구는 뇌졸중 후 상지기능의 관련 요인과 각 요인의 상대적 영향력을 알아보기 위해 시행되었다. MMSE-K(Mini Mental State Examination Korean version) 24점 이상인 100명의 뇌졸중 환자를 대상으로 하였다. 상지기능은 성별, 우세손, 뇌손상 원인, 뇌반구 손상부위, 신체마비 부위, 언어장애 유무와는 유의한 차이가 없었으나(p>0.05), 아탈구 유무는 상지기능에 유의한 차이를 보였다(p<0.05). 상지기능은 상지근력(Manual Muscle Testing), 고유수용성감각(Proprioception), 근 긴장도 (Modified Ashworth Scale), 장악력(Grip strength), 통증(Visual Analog Scale)과 상관관계를 보였다(p<0.05). 위의 변수를 모두 포함하여 분석하면 77.6%의 상지기능 설명력을 보였고 이 중 상지근력이 가장 높은 설명력을 보였다. 뇌졸중 환자의 상지기능 재활을 위해서는 특히 상지근력 강화와 더불어 고유수용성감각, 근 긴장도, 장악력, 통증 그리고 아탈구 유무의 관련 요인들을 포괄적으로 중재에 포함시켜야 할 것으로 사료된다.

• 한국콘텐츠학회논문지
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• 제9권10호
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• pp.227-237
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• 2009

본 연구는 지역사회 노인의 신체활동 참여에 따른 우울과 신체 기능을 알아봄으로서, 신체 활동을 노인의 지속적인 우울 경감 및 신체기능 증진을 위한 중재 방안으로 고려하기 위해 기초 자료를 제공하고자 하였다. 65세 이상 노인 79명이 참여 하였으며, 한국형 노인 우울 척도(KGDS), 한국형 간이 정신 상태 검사(MMSE-K), 젭슨 손 기능 검사(Jebsen hand function test), 악력계(Dynamometer), 5회 일어서기 검사(Five time sit-up test)를 이용하여 노인의 우울과 인지 및 신체 기능(손 기능, 장악력, 하지 근력)을 측정하였다. 연구 결과 노인의 우울감이 높을수록 장악력은 낮았고, 신체 활동에 참여한 노인은 참여하지 않은 노인에 비해 더 높은 신체 기능과 더 낮은 우울감을 보였다. 이는 신체 활동이 노인의 우울 경감 및 신체기능 증진과 관련을 나타내므로 신체 활동을 노인의 우울 상태 및 신체 기능의 예측과 관리의 전략으로 고려할 것을 제안하는 바이다.

• 한국보건간호학회지
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• 제20권2호
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• pp.119-129
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• 2006

Purpose: This study was conducted to investigate the status of depression and the cognitive function among the elderly over 65 years of age who use the welfare facilities for the aged in the community. Methods: For this study the data were collected from March 27, 2006 to April 14, 2006. Subjects were 92 elderly over 65 years old. The level of depression was estimated with the Beck Depression Inventory, and the cognitive function with the modified Mental Status Questionnaire (MSQ). The Data were analyzed using frequencies, t-test, and Pearson's correlation coefficient with the SPSS/PC program. Results: The results of this study are summarized as follows. 1. The mean score was 13.09 for depression and 8.27 for cognitive function. 2. Analysis according to the demographic characteristics confirmed a statistically significant difference on the level of cognitive function between the elderly who live alone and those who live together(f=4.293, p<0.01) 3. The percentage of the severely and mildly impaired in cognitive function was 7.6% and 6.5%, respectively. 4. The variables of age(f=11.17, p<0.01), educational level(f=15.23, p<0.01), martial status(f=4.084, p<0.01), and economic activity(t=4.41, p<0.01) showed a significant effect on cognitive function. 5. There was no relationship between depression and cognitive function. Conclusion: Social support and a variety of programs at welfare facilities in the community were recommended in order to reduce depression and cognitive impairment in the elderly.

• Maxillofacial Plastic and Reconstructive Surgery
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• 제18권4호
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• pp.652-672
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• 1996

Dysfunction of the inferior alveolar nerve may result from trauma, diseases or iatrogenic injury. The development and refinement of an objective method to evaluate this clinical problem is highly desirable and needed, especially concerning for an increasing medico-legal issue. Evoked potential techniques have attracted considerable attention as a means of assessing the function and integrity of nerve pathways. The purpose of this study was to characterize the Sensory Evoked Potentials(SEPs) and Somatosensory Evoked Potentials(SSEPs) elicited by electrical stimulation of mental nerve. SEPs and SSEPs were measured and analyzed statistically before and after needle injury on the inferior alveolar nerve of Sprague-Dawalye rats. Measuring SEPs was more sensitive in evaluation of the recovery of sensory function from inferior alveolar nerve injury then measuring SSEPs but we measured SSEPs in the hope of providing a safe, simple and objective test to check oral and facial sensibility, which is acceptable to the patient. We stimulated mental nerve after needle injury on the inferior alveolar nerve and SEPS on the level of mandibular foramen and SSEPs on the level of cerebral cortex were recorded. Threshold, amplitude, and latency of both of SEPs and SSEPs were analyzed. The results were as follows ; 1. Threshold of SEPs and SSEPs were $184{\pm}14{\mu}A$ and $164{\pm}14{\mu}A$ respectively. 2 SEPs were composed of 2 waves, i.e., N1 N2 in which N1 was conducted by II fibers and N2 was conducted by III fibers. 3. SSEPS were composed of 5 waves, of which N1 and N2 shower statistically significant changes(p<0.01, unpaired t-test). 4. SEPs and SSEPs were observed to be abolished immediately after local anesthesia and recovered 30 minutes later. 5. SEPs were abolished immediately after injury. N1 of SSEPs was abolished immediately and amplitued of N2 was decreased($20.7{\pm}12.2%$) immediately after 23G needle injury, but N3, N4 and N5 did not change significantly. Recovery of waveform delayed 30 minutes in SEPs and 45 minutes in SSEPs. 6. The degree of decrease in amplitude of SEPs and SSEPs, after 30G needle injury was smaller than those with 23G. SEPs recorded on the level of mandibular foramen were though to be reliable and useful in the assessment of the function of the inferior alveolar nerve after injury. Amplitude of SSEPs reflected the function and integrity of nerve and measuring them provided a safe, simple and abjective test to check oral and facial sensibility. These results suggest that measuring SEPs and SSEPs are meaningful methods for objective assessment in the diagnosis of nerve injury. N1 and N2 of SSEPs can be useful parameters for the evaluation of the nerve function following a needle injury.

• 생물정신의학
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• 제15권4호
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• pp.288-296
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• 2008

Objectives : We investigated the association of Val108/158Met polymorphism on catechol-O-methyl transferase(COMT) gene with smooth pursuit eye movement(SPEM) abnormality in Korean schizophrenia patients. Methods : We measured SPEM in 217 Korean schizophrenia patients(male 116, female 101) and divided them into two groups, one was a good SPEM function group and the other was a poor SPEM function group. Then we analyzed Val108/158Met polymorphism on COMT gene. We compared the differences of genotype and allele distributions of the polymorphism on COMT gene between the two groups. Results : The natural logarithm value of signal/noise ratio(Ln S/N ratio) of the good SPEM function group was $4.39{\pm}0.33$(mean${\pm}$s.d.) and that of poor SPEM function group was $3.17{\pm}0.71$. There were no statistically significant differences of age and male/female ratio between the two groups. There were no significant differences of genotype or allele distributions of the Val108/158Met polymorphism on COMT gene between the two schizophrenic groups. Conclusions : The results suggest that Val108/158Met polymorphism on COMT gene is not related to SPEM function abnormality in schizophrenia.